Proximal gastrectomy with tubular stomach reconstruction vs total gastrectomy for proximal gastric cancer following neoadjuvant chemotherapy: A multicenter retrospective study

doi:10.4240/wjgs.v17.i5.107579

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May 27, 2025 (publication date) through May 23, 2025

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. May 27, 2025; 17(5): 107579
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.107579

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Figure 1 Flowchart of the enrollment and matching. NACT: Neoadjuvant chemotherapy; PG: Proximal gastrectomy; TG: Total gastrectomy; PSM: Propensity score matching.

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Figure 2 Kaplan-Meier estimates of survival stratified by surgical groups. A: With a median follow-up of 36.8 months, the 5-year overall survival rates were 52.7% for the proximal gastrectomy (PG) group and 45.5% for the total gastrectomy (TG) group; B: The 5-year recurrence-free survival rates were 54.3% and 47.6% for the PG and TG groups. PG: Proximal gastrectomy; TG: Total gastrectomy.

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Figure 3 Forest plot of multivariate Cox regression analysis for overall survival. NACT: Neoadjuvant chemotherapy.

Citation: Lu YM, Jin P, Wang HK, Shao XX, Hu HT, Jiang YJ, Li WY, Tian YT. Proximal gastrectomy with tubular stomach reconstruction vs total gastrectomy for proximal gastric cancer following neoadjuvant chemotherapy: A multicenter retrospective study. World J Gastrointest Surg 2025; 17(5): 107579
URL: https://www.wjgnet.com/1948-9366/full/v17/i5/107579.htm
DOI: https://dx.doi.org/10.4240/wjgs.v17.i5.107579