Microbiota in patients with cefuroxime resistance and anal fistula revealed by 16S ribosomal DNA

Figure 1 Comparison of alpha diversity between cefuroxime-sensitive group and cefuroxime-resistant group based on different methods. A: Observed species; B: Chao1; C: ACE: Abundance-based coverage estimator; D: Shannon; E: Simpson; F: Inverse Simpson. Cefur-S: Cefuroxime-sensitive; Cefur-NS: Cefuroxime-resistant.

Figure 2 Comparison of beta diversity between cefuroxime-sensitive group and cefuroxime-resistant group based on different methods. A: Bray-Crutis; B: Jaccard; C: Unweighted unifrac; D: Weighted unifrac. Cefur-S: Cefuroxime-sensitive; Cefur-NS: Cefuroxime-resistant.

Figure 3 Linear discriminant analysis effect size analysis between cefuroxime-resistant and cefuroxime-sensitive. A: The cladogram of the linear discriminant analysis effect size result; B: The barplot of linear discriminant analysis score in cefuroxime-sensitive group. Cefur-S: Cefuroxime-sensitive; LDA: Linear discriminant analysis.

Figure 4 Correlation analysis of the bacterial community. A: Heatmap depicting correlations at the genus level; B: Heatmap depicting correlations at the phylum level.