Perioperative chemotherapy improves survival of patients with locally advanced diffuse gastric cancer

Figure 1 Kaplan-Meier survival curves for patients with diffuse gastric cancer receiving perioperative chemotherapy or surgery alone. A: The overall survival (OS) rates of patients who underwent perioperative chemotherapy or surgery alone; B: The cancer-specific survival (CSS) rates of patients who underwent perioperative chemotherapy or surgery alone; C: The OS rates of patients who underwent perioperative chemotherapy or surgery alone after inverse probability of treatment weighting (IPTW); D: The CSS rates of patients who underwent perioperative chemotherapy or surgery alone or surgery alone after IPTW. OS: Overall survival; CSS: Cancer-specific survival; IPTW: Inverse probability of treatment weighting.

Figure 2 Kaplan-Meier survival curves for patients with diffuse gastric cancer. A: Overall survival; B: Cancer-specific survival. N: Neoadjuvant chemotherapy, S: Surgery; A: Adjuvant chemotherapy.

Figure 3 Kaplan-Meier survival curves for patients with diffuse gastric cancer receiving neoadjuvant chemotherapy or adjuvant chemotherapy. A: The overall survival (OS) rates of patients who underwent perioperative chemotherapy; B: The cancer-specific survival (CSS) rates of patients who underwent perioperative chemotherapy; C: The OS rates of patients who underwent perioperative chemotherapy after inverse probability of treatment weighting (IPTW); D: The CSS rates of patients who underwent perioperative chemotherapy after IPTW. OS: Overall survival; CSS: Cancer-specific survival; IPTW: Inverse probability of treatment weighting.

Figure 4  Forest plot showing the subgroup analysis of the overall survival of patients receiving perioperative chemotherapy or surgery alone.

Figure 5  Forest plot showing the subgroup analysis of the overall survival of patients receiving neoadjuvant chemotherapy or adjuvant chemotherapy.