Evaluating effectiveness and safety of combined percutaneous transhepatic gallbladder drainage and laparoscopic cholecystectomy in acute cholecystitis patients: Meta-analysis

Figure 1 Flow diagram depicting the screening and inclusion process of the studies. CNKI: China National Knowledge Infrastructure.

Figure 2 Forest plot depicting comparison between the percutaneous transhepatic gallbladder puncture drainage + laparoscopic cholecystectomy group and the laparoscopic cholecystectomy group. A: Forest plot depicting the operation time comparison between the percutaneous transhepatic gallbladder puncture drainage (PTGBD) + laparoscopic cholecystectomy (LC) group and the LC group; B: Forest plot illustrating the comparison of the conversion rate to open surgery between the PTGBD + LC group and the LC group; C: Forest plot illustrating the comparison of intraoperative bleeding between the PTGBD + LC group and the LC group; D: Forest plot depicting the comparison of overall hospital stay between the PTGBD + LC group and the LC group; E: Forest plot depicting the comparison of postoperative hospital stay between the PTGBD + LC group and the LC group; F: Forest plot illustrating the comparison of postoperative complications between the PTGBD + LC group and the LC group; G: Forest plot illustrating the comparison of bile leakage rates between the PTGBD + LC group and the LC group; H: Forest plot depicting the comparison of wound infection rates between the PTGBD + LC group and the LC group; I: Forest plot depicting intraperitoneal hemorrhage in the PTGBD + LC group compared to the LC group; J: Forest plot comparing bile duct injury incidence between the PTGBD + LC group and the LC group. PTGBD: Percutaneous transhepatic gallbladder puncture drainage; LC: Laparoscopic cholecystectomy.

Figure 3 Funnel plots of each outcome. A: Operative time; B: Conversion rate to open surgery; C: Intraoperative bleeding; D: Overall hospital stay; E: Postoperative hospital stay; F: Postoperative complications; G: Bile leakage; H: Wound infection; I: Intraperitoneal hemorrhage; J: Bile duct injury. MD: Mean difference; OR: Odds ratio.