Clinical features of acute esophageal mucosal lesions and reflux esophagitis Los Angeles classification grade D: A retrospective study

Figure 1 Visual definition of endoscopic findings regarding reflux esophagitis Los Angeles classification grade D. A: In the lower esophagus; fused; the circumferential mucosal injury; B: Oral mucosal injury radially tapered off toward the oral side.

Figure 2 Visual definition of the endoscopic findings regarding the acute esophageal mucosal lesion. A: In the lower esophagus; fused; the circumferential mucosal injury; B: Oral mucosal injury was not spiny-shaped.

Figure 3 Visual definition of endoscopic findings regarding black esophagus. A: In the acute esophageal mucosal lesions group, black esophagus was defined as circumferentially appearing black esophageal mucosa; B: Even with a small amount of black component, we diagnosed black esophagus.

Figure 4 Visual definition of a hiatal hernia. Esophageal hiatal hernia was defined as a widening of the hilum with two or more scopes in the retroflex view of the endoscope.

Figure 5 Flow diagram of patient inclusion and exclusion. AEML: Acute esophageal mucosal lesions; RE-D: Reflux esophagitis Los Angeles classification grade D.

Figure 6 A case of esophageal stenosis. A 75-year-old male patient developed non-black esophagus acute esophageal mucosal lesions during chemotherapy for colorectal cancer. The patient could not eat on the 27^th day of onset. Upper endoscopy and esophagography showed esophageal stenosis. Symptoms improved after five endoscopic balloon dilatations. A: Upper endoscopy; B: Esophagography.