Assessment of tumor markers CA 19-9, CEA, CA 125, and CA 242 for the early diagnosis and prognosis prediction of gallbladder cancer

Figure 1  Stone size between patients with benign gallbladder disease and gall bladder cancer.

Figure 2 Receiver operating characteristic curve analysis showing diagnostic performance of carbohydrate antigen 19-9 (U/mL), carbohydrate antigen 125 (U/mL), carcinoembryonic antigen (µg/L), and carbohydrate antigen 242 (U/mL) in predicting gallbladder cancer vs benign gallbladder disease. ROC: Receiver operating characteristic curve.

Figure 3 Comparison of tumor marker levels of carbohydrate antigen 19-9, carbohydrate antigen 125, carcinoembryonic antigen, and carbohydrate antigen 242 before and after surgical management of gallbladder cancer. A: Carbohydrate antigen 19-9; B: Carbohydrate antigen 125; C: Carcinoembryonic antigen; D: Carbohydrate antigen 242.

Figure 4 Survival of patients with gallbladder cancer according to elevated vs normal marker levels of serum carbohydrate antigen 19-9 (U/mL), serum carbohydrate antigen 125 (U/mL), serum carcinoembryonic antigen (µg/L), and serum carbohydrate antigen 242 (U/mL) levels. A: Serum carbohydrate antigen 19-9 (U/mL); B: Serum carbohydrate antigen 125 (U/mL); C: Serum carcinoembryonic antigen (µg/L); D: Serum carbohydrate antigen 242 (U/mL).