Management of diabolical diabetes mellitus and periodontitis nexus: Are we doing enough?

Table 1 Meta-analyses depicting the effect of periodontal therapy on glycated hemoglobin in type 2 diabetes mellitus patients

Ref.	Year	Results	Conclusion
Janket et al[169]	2005	7 studies, n = 456	With SRP ↓HbA1c by 0.66% PT and antibiotics ↓HbA1c by 0.71%
Darré et al[170]	2008	9 studies, n = 485	PT ↓HbA1c by 0.79%
Garcia[171]	2009	9 studies, n = 485	PT ↓HbA1c by 0.79%
Teeuw et al[172]	2010	9 studies, n = 371	PT ↓HbA1c by 0.4% in 3 mo
Vergnes[173]	2010	7 studies, 3 studies results pooled	SRP (with/without antibiotics) ↓HbA1c by 0.4% in 3-4 mo
Simpson et al[174]	2010	7 studies, 3 studies results pooled	SRP (with/without antibiotics) ↓HbA1c by 0.4% in 3-4 mo
Sgolastra et al[175]	2013	5 studies	SRP ↓HbA1c by 0.65%
Liew et al[176]	2013	6 studies, n = 422	SRP without antibiotics ↓HbA1c by 0.64% in 3 mo
Corbella et al[177]	2013	15 studies	PT ↓HbA1c by 0.38% in 3-4 mo and 0.31% in 6 mo
Engebretson and Kocher[178]	2013	9 studies	PT ↓HbA1c by 0.36%
Wang et al[179]	2014	10 studies, n = 1135	PT ↓HbA1c by 0.36% in 3 mo and 0.30% in 6 mo
Sun et al[180]	2014	8 studies, n = 515	PT ↓HbA1c by 1.03% in 3 mo, 1.17% in 6 mo, 1.21% in 3, 6, 9 mo
Engebretson[181]	2014	7 studies, n = 678	PT ↓HbA1c by 0.38% in 3-4 mo and 0.31% in 6 mo
Li et al[182]	2015	9 studies, n = 1082	PT ↓HbA1c by 0.27% in 3 mo

PT: Periodontal treatment; T2DM: Type 2 diabetes mellitus; HbA1c: Glycated hemoglobin; SRP: Scaling and root planing; ↓: Reduced.