Copyright
©The Author(s) 2015.
World J Diabetes. Apr 15, 2015; 6(3): 508-516
Published online Apr 15, 2015. doi: 10.4239/wjd.v6.i3.508
Published online Apr 15, 2015. doi: 10.4239/wjd.v6.i3.508
Table 1 GTP-bound Rab27a effectors in pancreatic β-cells
| GTP-bound Rab27a effectors | Interacting proteins | Function |
| Exophillin8/Slac2-c/MyRIP | Myosin Va, Actin, PKA | Translocation |
| Slp4/Granuphilin | Munc18-1, Syntaxin1a,Myosin Va | Docking |
| Noc2 | Munc13-1 | - |
| Exophilin7/Slp1/JFC1 | - | Docking |
| Exophilin1/Rabphilin3A | Myosin Va | Translocation |
Table 2 GDP-bound Rab27a effectors in pancreatic β-cells
| GDP-bound Rab27a effectors | Interacting proteins | Function |
| Coronin 3/coronin 1c | F-actin | Actin bundling |
| Endocytosis | ||
| IQGAP1 | GTP-bound Cdc42 | Scaffold |
| GTP-bound Rac1 |
- Citation: Yamaoka M, Ishizaki T, Kimura T. Interplay between Rab27a effectors in pancreatic β-cells. World J Diabetes 2015; 6(3): 508-516
- URL: https://www.wjgnet.com/1948-9358/full/v6/i3/508.htm
- DOI: https://dx.doi.org/10.4239/wjd.v6.i3.508