Letter to the Editor: Enhancing the predictive value of body composition and adipokine assessment for gestational diabetes mellitus risk

doi:10.4239/wjd.118110

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Aug 15, 2026; 17(8): 118110
Published online Aug 15, 2026. doi: 10.4239/wjd.118110

Table 1 Proposed enhancements for gestational diabetes mellitus risk stratification

Dimension	Current metric[1]	Proposed enhancement	Clinical rationale	Refs
Adiposity	FMP	VFA	Stronger correlation with insulin resistance and cytokine release	Purnell[11], 2000
Kinetics	Pre-pregnancy BMI	Dynamic GWG trajectory	Reflects the body’s adaptive response to pregnancy demands	Hedderson et al[12], 2010
Behavioral	N/A	Validated lifestyle indices	Distinguishes between genetic predisposition and modifiable risk	Mijatovic-Vukas et al[13], 2018
Endocrine	Adiponectin/Leptin	Adiponectin-to-leptin ratio	Provides a more stable index of adipose health than individual markers	Davenport et al[14], 2018

FMP: Fat mass percentage; VFA: Visceral fat area; GWG: Gestational weight gain; BMI: Body mass index; N/A: Not available.

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Citation: Bhavthankar S, Gavkare AM, Nagoba BS. Letter to the Editor: Enhancing the predictive value of body composition and adipokine assessment for gestational diabetes mellitus risk. World J Diabetes 2026; 17(8): 118110
URL: https://www.wjgnet.com/1948-9358/full/v17/i8/118110.htm
DOI: https://dx.doi.org/10.4239/wjd.118110

Bhavthankar S, Gavkare AM, Nagoba BS. Letter to the Editor: Enhancing the predictive value of body composition and adipokine assessment for gestational diabetes mellitus risk. World J Diabetes 2026; 17(8): 118110 [DOI: 10.4239/wjd.118110]

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