Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway

Table 1 Name and weight of Chinese herbs in Kunkui Baoshen decoction

No.	Chinese name	Scientific name	Weight
1	Huangqi	Astmgali Radix	30 g
2	Huobahuagen	Tripterygium hypoglaucum	15 g
3	Jiuyurou	Fructus Ligustri Lucidi	10 g
4	Huangshukuihua	Corni Fructus Preparata	30 g

Table 2 Results of liquid chromatography-mass spectrometry/mass spectrometry analysis of Kunkui Baoshen decoction

Peak name	Retention time (minutes)	Mass-to-charge ratio (experiment)	Precursor type	Compound name	Pubchem number
1	2.990916667	389.1450240	M+H	Secologanin	161276
2	3.543550000	359.1343285	M+H	Sweroside	161036
3	4.055166667	447.1292902	M+H	Calycosin 7-O-beta-D-glucoside	5318267
4	4.055166667	465.1038809	M+H	Isoquercetin	5280804
5	4.055166667	303.0504691	M+H	Quercetin	5280343
6	4.076500000	301.0350797	M+H-H2O	Myricetin	5281672
7	4.319766667	287.0556821	M+H	Kaempferol	5280863
8	5.334866667	431.1343269	M+H	Ononin	442813
9	8.458666667	269.0813292	M+H	Formononetin	5280378