Copyright
©The Author(s) 2023.
World J Diabetes. Jul 15, 2023; 14(7): 1137-1145
Published online Jul 15, 2023. doi: 10.4239/wjd.v14.i7.1137
Published online Jul 15, 2023. doi: 10.4239/wjd.v14.i7.1137
Parameter | Values |
Age at onset (yr) | 42 |
Weight (kg) | 79.5 |
Height (cm) | 158 |
BMI (kg/m2) | 31.85 |
FBG (mmol/L) | 14.54 |
HbA1c (%) | 10.3 |
pH | 7.29 |
HCO3- (mmol/L) | 14.6 |
ABE | 16.6 |
SBE | 16.7 |
ICA (COI) | 45.20 |
GAD (IU/mL) | > 2000.00 |
IAA (COI) | 2.10 |
KET (mmol/L) | +- |
UA (µmol/L) | 484.7 |
TG (mmol/L) | 1.23 |
TC (mmol/L) | 4.22 |
HDL (mmol/L) | 1.01 |
LDL (mmol/L) | 2.89 |
ALT (U/L) | 44.8 |
AST (U/L) | 40.4 |
ALP (U/L) | 66.6 |
GGT (U/L) | 34.0 |
Ref. | Diagnosis | PAX4 variant | Ethnicity | Family history | Diagnostic age (yr) | Sex | BMI (kg/m2) | HbA1c, % | Insulin antibody, +/- | Treatment | HbA1c % at remission |
Sujjitjoon et al[22] | MODY9 | Heterozygous IVS7-1G>A | Thailand | Yes | 44 | Female | NA | NA | - | NA | NA |
Chapla et al[25] | MODY | Heterozygous c.92G>T | Asian-Indian | Yes | 14 | Male | 23 | NA | - | Glimepiride and insulin | NA |
Jo et al[19] | MODY | Heterozygous c.374-412 del 39 | Japanese | Yes | 15 | Male | 18.2 | 14.5 | - | Insulin | 7.4 |
Cho et al[20] | MODY | Homozygous c.575G>a | Korean | No | 22 | Male | 25.3 | 13.8 | NA | NA | NA |
Abreu et al[24] | MODY | Heterozygous c.491G>A | Brazilian | Yes | 32 | Female | 21.6 | NA | - | Insulin | NA |
Brazilian | Yes | 56 | Female | 29.48 | 11.3 | - | Metformin and gliclazide | NA | |||
Brazilian | Yes | 49 | Female | 23.61 | 6 | - | Metformin | NA | |||
Schmidt et al[21] | Ketosis-prone diabetes | Heterozygous c.109C>T | African | No | 38 | Male | 28.4 | > 14 | - | Insulin | 7.0 |
Mauvais-Jarvis et al[26] | Ketosis-prone diabetes | Homozygous R133W | West African | Yes | 47 | Male | 29.1 | 13.8 | - | Drugs | 6.6 |
West African | Yes | 22 | Male | 18.5 | 12.2 | - | Drugs | 5.1 | |||
West African | Yes | 38 | Male | 28.3 | 14.1 | - | Insulin | 6.2 | |||
West African | Yes | 20 | Male | 26.5 | 12.5 | - | Insulin | 7.3 | |||
Heterozygous R37W | West African | Yes | 39 | Male | 30.4 | 11.6 | - | Insulin | 8.2 | ||
Kanatsuka et al[27] | Late-onset diabetic | Homozygous R121W | Japanese | Yes | 37 | Male | 21.5 | 7.6 | - | Insulin | NA |
Japanese | No | 71 | Male | 22.8 | 7.1 | - | Insulin | NA | |||
Japanese | Yes | 71 | Female | 20.3 | 6.2 | + | Drugs | NA | |||
Shimajiri et al[23] | T2DM | Homozygous R121W | Japanese | No | 29 | Female | 22.2 | 12.6 | - | Insulin | 7.3 |
Present case | T1DM | Heterozygous c.314G>A | Chinese | No | 42 | Female | 31.85 | 10.3 | + | Lifestyle control | 7.3 |
- Citation: Zhou GH, Tao M, Wang Q, Chen XY, Liu J, Zhang LL. Maturity-onset diabetes of the young type 9 or latent autoimmune diabetes in adults: A case report and review of literature. World J Diabetes 2023; 14(7): 1137-1145
- URL: https://www.wjgnet.com/1948-9358/full/v14/i7/1137.htm
- DOI: https://dx.doi.org/10.4239/wjd.v14.i7.1137