Validity and reliability of the Polish version of the Michigan Neuropathy Screening Instrument

Table 1 General sample characteristics

Variable, n = 80	Sex	Descriptive statistics					Mann-Whitney U test
		Valid (n)	Mean	Minimum	Maximum	SD	Pvalue
Age (yr)	Female	39	69.00	45.00	80.00	6.27	0.151516
	Male	41	65.32	37.00	76.00	9.56
Weight (kg)	Female	39	77.36	54.00	108.00	12.24	2.55E-03
	Male	41	88.66	63.00	150.00	16.52
Height (cm)	Female	39	161.38	150.00	174.00	5.97	1.78E-11
	Male	41	175.15	164.00	190.00	6.90
BMI (kg/m2)	Female	39	29.68	21.90	40.20	4.52	2.64E-01
	Male	41	28.84	21.50	44.30	4.90
HbA1c (%)	Female	38	6.42	5.20	8.50	0.79	4.87E-01
	Male	40	6.58	5.00	8.80	0.97
DM1 duration (yr)	Female	39	12.10	0.00	37.00	8.13	2.90E-01

¹Diabetes mellitus duration for less than 6 mo = 0, between 6-12 mo = 1 year.

BMI: Body mass index; DM: Diabetes mellitus; HbA1c: Glycated hemoglobin; SD: Standard deviation.

Table 2 Reliability results for the patient and practitioner sections of the Michigan Neuropathy Screening Instrument-Polish version

Part A of MNSI			Part B of MNSI
n = 80	Cronbach alpha, full scale: 0.81790		Cronbach alpha, full scale: 0.87095
	Corr 1st & 2nd half: 0.745791		Corr 1st & 2nd half: 0.972206
	Split-half reliability: 0.854388		Split-half reliability: 0.985907
	Guttman split-half: 0.840785		Guttman split-half: 0.985838
	Summary for A1	Summary for A2	Summary for B1	Summary for B2
Mean	4.250000	4.150000	6.212500	6.175000
Sum	340.0000	332.0000	497.0000	494.0000
SD	3.403275	4.313946	3.925553	3.860790
Variance	11.58228	18.61013	15.40997	14.90570
Cronbach alpha	0.6499672	0.7060083	0.7337023	0.7346509

A1: Patient version; A2: Patient version (after 1-2 wk); B1: Patient examination; B2: Patient examination (after 1-2 wk); MNSI-PL: Michigan Neuropathy Screening Instrument-Polish version; SD: Standard deviation.

Table 3 Stability of the patient and practitioner sections of the Michigan Neuropathy Screening Instrument-Polish version

Part of MNSI	Mean (SD)		ICC for agreement		ICC for consistency
	Test score	Re-test score	ICCagreement	Pvalue	ICCconsistency	Pvalue
A	2.125 (1.70)	2.075 (2.16)	0.728	9.05E-15	0.725	9.47E-15
B	3.106 (1.96)	3.088 (1.93)	0.972	6.19E-52	0.972	8.53E-52

Part A: Patient version of Michigan Neuropathy Screening Instrument; Part B: Patient examination. ICC: Intraclass correlation coefficient; MNSI-PL: Michigan Neuropathy Screening Instrument-Polish version.

Table 4 The area under the curve values for Nerve Conduction Study and Michigan Neuropathy Screening Instrument Polish version (version A and B) at both time points

Variable	AUC	Pvalue
A1	0.749	0.0003
B1	0.796	0.0000
A2	0.617	0.2296
B2	0.770	0.0001

A1: Patient version; A2: Patient version (after 1-2 wk); AUC: Area under the curve; B1: Patient examination; B2: Patient examination (after 1-2 wk).

Table 5 The cut-off points for Michigan Neuropathy Screening Instrument Polish version at the two time points and their sensitivity and specificity, and their positive and negative predictive values based on receiver operating characteristic curves

Variable	True positives, n, %	False positives, n, %	False negatives, n, %	True negatives, n, %	Sensitivity	Specificity	Optimal cut-off point
A1	28/35	0/0	42/52.5	10/12.5	0.400	1.000	3
B1	57/71.25	3/3.75	13/16.25	7/8.75	0.814	0.700	2
A2	23/28.75	1/1.25	47/58.75	9/11.25	0.329	0.900	3
B2	59/73.75	4/5	11/13.75	6/7.5	0.843	0.600	2

A1: Patient version; A2: Patient version (after 1-2 wk); B1: Patient examination; B2: Patient examination (after 1-2 wk).