Targeting gut microbiota: Potential mechanisms in the pathogenesis of type 2 diabetes mellitus and emerging translational intervention strategies

doi:10.4239/wjd.122293

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World Journal of Diabetes

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1948-9358

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Sep 15, 2026; 17(9): 122293
Published online Sep 15, 2026. doi: 10.4239/wjd.122293

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Figure 1 Gut microbiota involvement in the regulation of type 2 diabetes mellitus. T2DM: Type 2 diabetes; LPS: Lipopolysaccharide; SCFA: Short-chain fatty acid; TCM: Traditional Chinese medicine; HbA1c: Glycated hemoglobin; FBG: Fasting blood glucose; NF-κB: Nuclear factor-kappa B; IL: Interleukin; TNF: Tumor necrosis factor; AMPK: Adenosine 5’-monophosphate-activated protein kinase; GLUT4: Glucose transporter 4.

Citation: Xie FJ, Zhang M, Li WT, Zhou WY, Ma HB, Xu Y, Bi LM. Targeting gut microbiota: Potential mechanisms in the pathogenesis of type 2 diabetes mellitus and emerging translational intervention strategies. World J Diabetes 2026; 17(9): 122293
URL: https://www.wjgnet.com/1948-9358/full/v17/i9/122293.htm
DOI: https://dx.doi.org/10.4239/wjd.122293

Xie FJ, Zhang M, Li WT, Zhou WY, Ma HB, Xu Y, Bi LM. Targeting gut microbiota: Potential mechanisms in the pathogenesis of type 2 diabetes mellitus and emerging translational intervention strategies. World J Diabetes 2026; 17(9): 122293 [DOI: 10.4239/wjd.122293]

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