Peri-colonoscopy hypoglycaemia in type 2 diabetes: Temporal patterns and asymptomatic presentation

Figure 1 Temporal distribution of hypoglycaemic events and identification of dual high-risk windows during the peri-colonoscopy period. Blue bars indicate incidence rates (left Y-axis); orange bars indicate asymptomatic proportions (right Y-axis). The two Y-axes represent different metrics and should not be interpreted as implying a direct quantitative relationship. Two high-risk windows are highlighted: (1) Early bowel preparation window (20:00-06:00) (highest asymptomatic proportion, 70.5%); and (2) Immediate post-colonoscopy (highest incidence rate, 6.93). pt-h: Patient-hours.

Figure 2 Forest plot of multivariable generalised estimating equations analysis for factors associated with asymptomatic hypoglycaemia. Orange indicates risk factors (odds ratio > 1); blue indicates protective factors (odds ratio < 1). The model used an exchangeable working correlation structure. OR: Odds ratio.

Figure 3 Exploratory risk stratification for asymptomatic hypoglycaemia based on retinopathy status and timing of occurrence. Asymptomatic proportions across four exploratory risk strata based on retinopathy status and timing of occurrence. This stratification is hypothesis-generating and requires prospective external validation before clinical implementation. P for trend < 0.001 (generalised estimating equations logistic model with ordinal risk score).