Post vitrectomy alterations of retinal microcirculation in complicated diabetic retinopathy with and without silicone oil

Figure 1 Participant flow diagram. This flowchart depicts the screening, eligibility assessment, and exclusion of eyes enrolled in this retrospective observational study. DR: Diabetic retinopathy; PPV: Pars plana vitrectomy; OCTA: Optical coherence tomography angiography; SO: Silicone oil; SOR: Silicone oil removal.

Figure 2 Representative optical coherence tomography angiography images illustrating the measurement of retinal microcirculatory parameters. A: Measurement of retinal thickness; B: Measurement of the foveal avascular zone area; C: Measurement of vascular density (VD) in the superficial capillary plexus (SCP); D: Measurement of VD in the deep capillary plexus (DCP); E and F: Representative B-scan images showing the segmentation boundaries of the SCP and DCP.

Figure 3 Longitudinal changes in optical coherence tomography angiography parameters before and after silicone oil removal. A: Longitudinal changes in retinal thickness in three regions at four consecutive time points, with no significant differences; B: Longitudinal changes in vascular density (VD) in the superficial capillary plexus in the three regions, with no significant differences; C: Longitudinal changes in VD in the deep capillary plexus in the three regions; D: Longitudinal changes in the foveal avascular zone area; E: Longitudinal changes in best-corrected visual acuity. ^aP < 0.05. VD: Vascular density; DCP: Deep capillary plexus; FAZ: Foveal avascular zone; SCP: Superficial capillary plexus; BCVA: Best-corrected visual acuity; RT: Retinal thickness; SO: Silicone oil; SOR: Silicone oil removal.