Copyright
©The Author(s) 2025.
World J Diabetes. Jul 15, 2025; 16(7): 107344
Published online Jul 15, 2025. doi: 10.4239/wjd.v16.i7.107344
Published online Jul 15, 2025. doi: 10.4239/wjd.v16.i7.107344
Figure 1 Mechanisms of stem cell therapy for diabetes mellitus.
This figure outlines the mechanisms by which stem cell therapy addresses diabetes. It includes the differentiation of stem cells into insulin-producing β-cells, paracrine effects that promote β-cell regeneration, and immunomodulation that reduces autoimmune damage and inflammation. Collectively, these processes enhance glucose regulation and facilitate pancreatic repair. ESC: Embryonic stem cells; iPSC: Induced pluripotent stem cells; MSC: Mesenchymal stem cell; T1DM: Type 1 diabetes mellitus.
- Citation: Zuo DB, Wang CH, Sang M, Sun XD, Chen GP, Ji KK. Stem cell therapy for diabetes: Advances, prospects, and challenges. World J Diabetes 2025; 16(7): 107344
- URL: https://www.wjgnet.com/1948-9358/full/v16/i7/107344.htm
- DOI: https://dx.doi.org/10.4239/wjd.v16.i7.107344