Effect of resveratrol in gestational diabetes mellitus and its complications

doi:10.4239/wjd.v14.i6.808

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Jun 15, 2023; 14(6): 808-819
Published online Jun 15, 2023. doi: 10.4239/wjd.v14.i6.808

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Figure 1 Chemical structures of trans-resveratrol (3,5,4'-trihydroxystilbene) and cis-resveratrol. A: Trans-resveratrol; B: Cis-resveratrol.

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Figure 2 Pathway and targets of resveratrol in gestational diabetes mellitus. AMPK: AMP-activated protein kinase; CK: Creatine kinase; CRP: C-reactive protein; CX3CL1: CX3C chemokine ligand 1; ERK: Extracellular signal-regulated kinase; GLUT1: Glucose transporter type 1; IL: Interleukin; JNK: C-Jun N-terminal kinase; LDH: Lactate dehydrogenase; MAPK: Mitogen-activated protein kinase; NOV: Nephroblastoma overexpressed; RAR: Retinoic acid receptor; RAX: RNA-dependent protein kinase-associated protein X; ROS: Reactive oxygen species; SIRT: Sirtuin; TNF-α: Tumor necrosis factor-alpha.

Citation: Ma HZ, Chen Y, Guo HH, Wang J, Xin XL, Li YC, Liu YF. Effect of resveratrol in gestational diabetes mellitus and its complications. World J Diabetes 2023; 14(6): 808-819
URL: https://www.wjgnet.com/1948-9358/full/v14/i6/808.htm
DOI: https://dx.doi.org/10.4239/wjd.v14.i6.808