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Cited by in CrossRef
For: He HJ, Wang GY, Gao Y, Ling WH, Yu ZW, Jin TR. Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice. World J Diabetes 2012; 3(5): 94-104 [PMID: 22645638 DOI: 10.4239/wjd.v3.i5.94]
URL: https://www.wjgnet.com/1948-9358/full/v3/i5/94.htm
Number Citing Articles
1
Joyce Trujillo, Luis Fernando Granados‐Castro, Cecilia Zazueta, Ana Cristina Andérica‐Romero, Yolanda Irasema Chirino, José Pedraza‐Chaverrí. Mitochondria as a Target in the Therapeutic Properties of CurcuminArchiv der Pharmazie 2014; 347(12) doi: 10.1002/ardp.201400266
2
Tanushree Karmakar, Rituparna Chaki, Nilanjan Ghosh. Evidence Based Validation of Traditional Medicines2021;  doi: 10.1007/978-981-15-8127-4_49
3
Lina Xu, Yue Li, Yan Dai, Jinyong Peng. Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanismsPharmacological Research 2018; 130 doi: 10.1016/j.phrs.2018.01.015
4
Kamila Kasprzak-Drozd, Tomasz Oniszczuk, Marek Gancarz, Adrianna Kondracka, Robert Rusinek, Anna Oniszczuk. Curcumin and Weight Loss: Does It Work?International Journal of Molecular Sciences 2022; 23(2) doi: 10.3390/ijms23020639
5
Isabella Savini, Maria Catani, Daniela Evangelista, Valeria Gasperi, Luciana Avigliano. Obesity-Associated Oxidative Stress: Strategies Finalized to Improve Redox StateInternational Journal of Molecular Sciences 2013; 14(5) doi: 10.3390/ijms140510497
6
Yildiz Öner-İyidoğan, Hikmet Koçak, Muhammed Seyidhanoğlu, Figen Gürdöl, Ahmet Gülçubuk, Funda Yildirim, Aydin Çevik, Müjdat Uysal. Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat dietJournal of Physiology and Biochemistry 2013; 69(4) doi: 10.1007/s13105-013-0244-9
7
Hahnbie Lee, Seung-Woo Kim, Hye-Kyung Lee, Lidan Luo, Il-Doo Kim, Ja-Kyeong Lee. Upregulation of Nrf2–p300 mediates anti-inflammatory effects of curcumin in microglia by downregulating p65–p300Animal Cells and Systems 2016; 20(5) doi: 10.1080/19768354.2016.1223169
8
Zeinab Vafaeipour, Bibi Marjan Razavi, Hossein Hosseinzadeh. Effects of turmeric (Curcuma longa) and its constituent (curcumin) on the metabolic syndrome: An updated reviewJournal of Integrative Medicine 2022; 20(3) doi: 10.1016/j.joim.2022.02.008
9
C. Sumathi Jones, V. Uma Maheshwari Nallal, M. Razia. Emerging Nanomaterials for Advanced TechnologiesNanotechnology in the Life Sciences 2022;  doi: 10.1007/978-3-030-80371-1_8
10
Fatemeh Pourhabibi‐Zarandi, Maryam Rafraf, Habib Zayeni, Mohammad Asghari‐Jafarabadi, Ali‐Asghar Ebrahimi. Effects of curcumin supplementation on metabolic parameters, inflammatory factors and obesity values in women with rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled clinical trialPhytotherapy Research 2022; 36(4) doi: 10.1002/ptr.7422
11
Indrani Sinha-Hikim, Theodore C. Friedman, Chang-Sung Shin, Desean Lee, Rasheed Ivey, Amiya P. Sinha-Hikim. Nicotine in Combination With a High-Fat Diet Causes Intramyocellular Mitochondrial Abnormalities in Male MiceEndocrinology 2014; 155(3) doi: 10.1210/en.2013-1795
12
Alfred Najm, Adelina-Gabriela Niculescu, Alexandru Mihai Grumezescu, Mircea Beuran. Emerging Therapeutic Strategies in Sarcopenia: An Updated Review on Pathogenesis and Treatment AdvancesInternational Journal of Molecular Sciences 2024; 25(8) doi: 10.3390/ijms25084300
13
Jiahui Chen, Kunhong Xie, Bing Yu, Yuheng Luo, Hui Yan, Ping Zheng, Xiangbing Mao, Jie Yu, Quyuan Wang, Jun He. Dietary supplementation of curcumin improves growth performance, carcass traits and meat quality in growing-finishing pigsJournal of Functional Foods 2026; 141 doi: 10.1016/j.jff.2026.107310
14
Esimebia Adjovi Amegashie, Ruth Oyawole Sikeola, Emmanuel Ayitey Tagoe, Elijah Paintsil, Kwasi Torpey, Osbourne Quaye. Oxidative Stress in People Living With HIV: Are Diverse Supplement Sources the Solution?Health Science Reports 2025; 8(5) doi: 10.1002/hsr2.70824
15
R. Sivaranjani, T. John Zachariah, N. K. Leela. Phytotherapeutic potential of bi-herbal extract of cinnamon and turmeric: in vivo antidiabetic studiesClinical Phytoscience 2021; 7(1) doi: 10.1186/s40816-021-00275-3
16
Zhenxing Xie, Shufang Xia, Guo-Wei Le. Gamma-aminobutyric acid improves oxidative stress and function of the thyroid in high-fat diet fed miceJournal of Functional Foods 2014; 8 doi: 10.1016/j.jff.2014.03.003
17
Baoxiang Zhang, Jing Wang, Guodong Zhao, Mao Lin, Yong Lang, Diancai Zhang, Dianqin Feng, Caixia Tu. Apigenin protects human melanocytes against oxidative damage by activation of the Nrf2 pathwayCell Stress and Chaperones 2020; 25(2) doi: 10.1007/s12192-020-01071-7
18
Adeline Lum Nde, Chika I. Chukwuma, Ochuko L. Erukainure, Maria S. Chukwuma, Motlalepula G. Matsabisa. Ethnobotanical, phytochemical, toxicology and anti-diabetic potential of Senna occidentalis (L.) link; A reviewJournal of Ethnopharmacology 2022; 283 doi: 10.1016/j.jep.2021.114663
19
Tina Nie, Garth J. S. Cooper. Mechanisms Underlying the Antidiabetic Activities of Polyphenolic Compounds: A ReviewFrontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.798329
20
Wensong Lu, Fedora Khatibi Shahidi, Khatereh Khorsandi, Reza Hosseinzadeh, Asma Gul, Veronica Balick. An update on molecular mechanisms of curcumin effect on diabetesJournal of Food Biochemistry 2022; 46(10) doi: 10.1111/jfbc.14358
21
Eun Soo Lee, Mi-Hye Kwon, Hong Min Kim, Nami Kim, You Mi Kim, Hyeon Soo Kim, Eun Young Lee, Choon Hee Chung. Dibenzoylmethane ameliorates lipid-induced inflammation and oxidative injury in diabetic nephropathyJournal of Endocrinology 2019; 240(2) doi: 10.1530/JOE-18-0206
22
Shishir Shishodia. Molecular mechanisms of curcumin action: Gene expressionBioFactors 2013; 39(1) doi: 10.1002/biof.1041
23
Zhiguo Zhang, Shanshan Zhou, Xin Jiang, Yue-Hui Wang, Fengsheng Li, Yong-Gang Wang, Yang Zheng, Lu Cai. The role of the Nrf2/Keap1 pathway in obesity and metabolic syndromeReviews in Endocrine and Metabolic Disorders 2015; 16(1) doi: 10.1007/s11154-014-9305-9
24
Matthew Dodson, Montserrat Rojo de la Vega, Aram B. Cholanians, Cody J. Schmidlin, Eli Chapman, Donna D. Zhang. Modulating NRF2 in Disease: Timing Is EverythingAnnual Review of Pharmacology and Toxicology 2019; 59(1) doi: 10.1146/annurev-pharmtox-010818-021856
25
Ludmila F.M.F. Cardozo, Liliana M. Pedruzzi, Peter Stenvinkel, Milena B. Stockler-Pinto, Julio B. Daleprane, Maurilo Leite, Denise Mafra. Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2Biochimie 2013; 95(8) doi: 10.1016/j.biochi.2013.04.012
26
Andrix O. Arguelles, Sunitha Meruvu, John D. Bowman, Mahua Choudhury. Are epigenetic drugs for diabetes and obesity at our door step?Drug Discovery Today 2016; 21(3) doi: 10.1016/j.drudis.2015.12.001
27
Mohammad Mohajeri, Reza Momenai, Somayyeh Karami-Mohajeri, Mandana Ohadi, Mohammad Amin Raeisi Estabragh. Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of ActionIranian Journal of Pharmaceutical Research 2025; 24(1) doi: 10.5812/ijpr-156983
28
Tianru Jin, Zhuolun Song, Jianping Weng, I. George Fantus. Curcumin and other dietary polyphenols: potential mechanisms of metabolic actions and therapy for diabetes and obesityAmerican Journal of Physiology-Endocrinology and Metabolism 2018; 314(3) doi: 10.1152/ajpendo.00285.2017
29
Angélica Saraí Jiménez-Osorio, Susana González-Reyes, José Pedraza-Chaverri. Natural Nrf2 activators in diabetesClinica Chimica Acta 2015; 448 doi: 10.1016/j.cca.2015.07.009
30
Manuel Matzinger, Katrin Fischhuber, Elke H. Heiss. Activation of Nrf2 signaling by natural products-can it alleviate diabetes?Biotechnology Advances 2018; 36(6) doi: 10.1016/j.biotechadv.2017.12.015
31
Michal Krawczyk, Izabela Burzynska-Pedziwiatr, Lucyna A. Wozniak, Malgorzata Bukowiecka-Matusiak. Impact of Polyphenols on Inflammatory and Oxidative Stress Factors in Diabetes Mellitus: Nutritional Antioxidants and Their Application in Improving Antidiabetic TherapyBiomolecules 2023; 13(9) doi: 10.3390/biom13091402
32
Vivian Soetikno, Wawaimuli Arozal, Melva Louisa, Rianto Setiabudy. New Insight into the Molecular Drug Target of Diabetic NephropathyInternational Journal of Endocrinology 2014; 2014 doi: 10.1155/2014/968681
33
Jin Won Yang, Hee Kyung Yeo, Jee Hye Yun, Jung Un Lee. Theracurmin (Highly Bioavailable Curcumin) Prevents High Fat Diet-Induced Hepatic Steatosis Development in MiceToxicological Research 2019; 35(4) doi: 10.5487/TR.2019.35.4.403
34
Maura Calvani, Amada Pasha, Claudio Favre. Nutraceutical Boom in Cancer: Inside the Labyrinth of Reactive Oxygen SpeciesInternational Journal of Molecular Sciences 2020; 21(6) doi: 10.3390/ijms21061936
35
Siti Liyana Saud Gany, Kok-Yong Chin, Jen Kit Tan, Amilia Aminuddin, Suzana Makpol. Curcumin as a Therapeutic Agent for SarcopeniaNutrients 2023; 15(11) doi: 10.3390/nu15112526
36
Bo-hyun Choi, Kyung-Shin Kang, Mi-Kyoung Kwak. Effect of Redox Modulating NRF2 Activators on Chronic Kidney DiseaseMolecules 2014; 19(8) doi: 10.3390/molecules190812727
37
Wylly Ramsés García-Niño, Edilia Tapia, Cecilia Zazueta, Zyanya Lucía Zatarain-Barrón, Rogelio Hernández-Pando, Claudia Cecilia Vega-García, José Pedraza-Chaverrí. Curcumin Pretreatment Prevents Potassium Dichromate-Induced Hepatotoxicity, Oxidative Stress, Decreased Respiratory Complex I Activity, and Membrane Permeability Transition Pore OpeningEvidence-Based Complementary and Alternative Medicine 2013; 2013 doi: 10.1155/2013/424692
38
Troy L. Merry, Michael Ristow. Nuclear factor erythroid‐derived 2‐like 2 (NFE2L2, Nrf2) mediates exercise‐induced mitochondrial biogenesis and the anti‐oxidant response in miceThe Journal of Physiology 2016; 594(18) doi: 10.1113/JP271957
39
Romilly E. Hodges, Deanna M. Minich. Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical ApplicationJournal of Nutrition and Metabolism 2015; 2015 doi: 10.1155/2015/760689
40
Zi-yu ZHOU, Li-wei REN, Han-yan YANG, Ji-zhang LIU, Ke-dan CHU, Jian-ping WENG, Zhi-wen YU. Effect of short-term acumagnetotherapy on diabetic kidney disease in patients with type II diabetes and study on the molecular mechanismWorld Journal of Acupuncture - Moxibustion 2015; 25(3) doi: 10.1016/S1003-5257(15)30056-8
41
Matthew Dodson, Aryatara Shakya, Annadurai Anandhan, Jinjing Chen, Joe G.N. Garcia, Donna D. Zhang. NRF2 and Diabetes: The Good, the Bad, and the ComplexDiabetes 2022; 71(12) doi: 10.2337/db22-0623
42
Estelle Hirzel, Peter W. Lindinger, Swarna Maseneni, Maria Giese, Véronique Virginie Rhein, Anne Eckert, Matthias Hoch, Stephan Krähenbühl, Alex N. Eberle. Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytesJournal of Receptors and Signal Transduction 2013; 33(5) doi: 10.3109/10799893.2013.822887
43
Mariapaola Nitti, Barbara Marengo, Anna Lisa Furfaro, Maria Adelaide Pronzato, Umberto Maria Marinari, Cinzia Domenicotti, Nicola Traverso. Hormesis and Oxidative Distress: Pathophysiology of Reactive Oxygen Species and the Open Question of Antioxidant Modulation and SupplementationAntioxidants 2022; 11(8) doi: 10.3390/antiox11081613
44
Karthika Kannan, Jissy Anna George, Revathy Sahadevan, Manan Kothari, Sushabhan Sadhukhan. Insights into one drug, multi-target aspects of polyphenols for diabetes management: in vitro, in vivo, and clinical evidencePhytochemistry Reviews 2025; 24(5) doi: 10.1007/s11101-024-10047-9
45
Shatadal Ghosh, Sharmistha Banerjee, Parames C. Sil. The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent updateFood and Chemical Toxicology 2015; 83 doi: 10.1016/j.fct.2015.05.022
46
Yıldız Öner-İyidoğan, Sevda Tanrıkulu-Küçük, Muhammed Seyithanoğlu, Hikmet Koçak, Semra Doğru-Abbasoğlu, A. Fatih Aydın, Şule Beyhan-Özdaş, Hande Yapışlar, Necla Koçak-Toker. Effect of curcumin on hepatic heme oxygenase 1 expression in high fat diet fed rats: is there a triangular relationship?Canadian Journal of Physiology and Pharmacology 2014; 92(10) doi: 10.1139/cjpp-2014-0174
47
JOO WAN KIM, SAE-KWANG KU, MIN HO HAN, KI YOUNG KIM, SUNG GOO KIM, GI-YOUNG KIM, HYE JIN HWANG, BYUNG WOO KIM, CHEOL MIN KIM, YUNG HYUN CHOI. The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in miceInternational Journal of Molecular Medicine 2015; 36(1) doi: 10.3892/ijmm.2015.2200
48
Jingyi Li, Shushen Sun, Ying Li, Mengzhe Tian, Xinyi Li, Suxia Ren, Zengyi Huang, Yiwen Wang, Shaoshan Du. Nrf2 signaling pathway studies in Drosophila melanogaster : parallel roles in human health and insect environmental responses Xenobiotica 2025; 55(2) doi: 10.1080/00498254.2025.2465239
49
Xin Wang, Chunxu Hai. Redox modulation of adipocyte differentiation: hypothesis of “Redox Chain” and novel insights into intervention of adipogenesis and obesityFree Radical Biology and Medicine 2015; 89 doi: 10.1016/j.freeradbiomed.2015.07.012
50
Tânia Martins, Bruno Colaço, Carlos Venâncio, Maria J Pires, Paula A Oliveira, Eduardo Rosa, Luís M Antunes. Potential effects of sulforaphane to fight obesityJournal of the Science of Food and Agriculture 2018; 98(8) doi: 10.1002/jsfa.8898
51
M. T. Lee, W. C. Lin, B. Yu, T. T. Lee. Antioxidant capacity of phytochemicals and their potential effects on oxidative status in animals — A reviewAsian-Australasian Journal of Animal Sciences 2016; 30(3) doi: 10.5713/ajas.16.0438
52
Paul M. Rindler, Clair L. Crewe, Jolyn Fernandes, Michael Kinter, Luke I. Szweda. Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondriaAmerican Journal of Physiology-Heart and Circulatory Physiology 2013; 305(5) doi: 10.1152/ajpheart.00799.2012
53
Catarina Andrade, Nelson G.M. Gomes, Sutsawat Duangsrisai, Paula B. Andrade, David M. Pereira, Patrícia Valentão. Medicinal plants utilized in Thai Traditional Medicine for diabetes treatment: Ethnobotanical surveys, scientific evidence and phytochemicalsJournal of Ethnopharmacology 2020; 263 doi: 10.1016/j.jep.2020.113177
54
Shu Wang, Naima Moustaid-Moussa, Lixia Chen, Huanbiao Mo, Anuradha Shastri, Rui Su, Priyanka Bapat, InSook Kwun, Chwan-Li Shen. Novel insights of dietary polyphenols and obesityThe Journal of Nutritional Biochemistry 2014; 25(1) doi: 10.1016/j.jnutbio.2013.09.001
55
Rabah Rashad Falah, Wamidh H. Talib, Seba Jamal Shbailat. Combination of metformin and curcumin targets breast cancer in mice by angiogenesis inhibition, immune system modulation and induction of p53 independent apoptosisTherapeutic Advances in Medical Oncology 2017; 9(4) doi: 10.1177/1758834016687482
56
Jung Eun Kim, Hye Ran Kim, Jin Cheol Kim, Eun Soo Lee, Choon Hee Chung, Eun Young Lee, Bo Young Chung, Maxim E. Darvin. Tetrahydrocurcumin Ameliorates Skin Inflammation by Modulating Autophagy in High‐Fat Diet‐Induced Obese MiceBioMed Research International 2021; 2021(1) doi: 10.1155/2021/6621027
57
Malihe Mohamadian, Negin Parsamanesh, Hossein Chiti, Thozhukat Sathyapalan, Amirhossein Sahebkar. Protective effects of curcumin on ischemia/reperfusion injuryPhytotherapy Research 2022; 36(12) doi: 10.1002/ptr.7620
58
Elizabeth Foluke Awodire, Ayokunle Olubode Ademosun, Olufunke Florence Ajeigbe, Ganiyu Oboh. Functional foods and their applications in managing globally common disease-linked comorbiditiesFood Materials Research 2023; 3(1) doi: 10.48130/fmr-0023-0034
59
Florent Auger, Françoise Martin, Olivier Pétrault, Jennifer Samaillie, Thierry Hennebelle, Mohamed-Sami Trabelsi, François Bailleul, Bart Staels, Régis Bordet, Patrick Duriez. Risperidone-induced metabolic dysfunction is attenuated by Curcuma longa extract administration in miceMetabolic Brain Disease 2018; 33(1) doi: 10.1007/s11011-017-0133-y
60
Shahnaz Rajabi, Majid Darroudi, Kobra Naseri, Tahereh Farkhondeh, Saeed Samarghandian. Protective Effects of Curcumin and its Analogues via the Nrf2 Pathway in Metabolic SyndromeCurrent Medicinal Chemistry 2024; 31(25) doi: 10.2174/0929867330666230510101150
61
Shabnoor Iqbal, Muhammad Ajmal Shah, Azhar Rasul, Shahid Shah, Ghulam Mujtaba Shah, Muhammad Irfan, Uzma Saleem, Ifat Alsharif, Reem Hasaballah Alhasani, Norah A. Althobaiti, Shafiq Ur Rahman, Abdul Haleem Khan. The Role of Phytonutrients in Metabolic Disorders2022;  doi: 10.1016/B978-0-12-824356-5.00013-8
62
Dong Liu, Yanglin Ji, Kexin Wang, Yatu Guo, Huali Wang, Hua Zhang, Liwei Li, Heyu Li, Steve W. Cui, Hao Wang. Purple sweet potato anthocyanin extract regulates redox state related to gut microbiota homeostasis in obese miceJournal of Food Science 2022; 87(5) doi: 10.1111/1750-3841.16130
63
Chunlai Zeng, Peng Zhong, Yunjie Zhao, Karvannan Kanchana, Yali Zhang, Zia A. Khan, Subrata Chakrabarti, Lianpin Wu, Jingying Wang, Guang Liang. Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivoJournal of Molecular and Cellular Cardiology 2015; 79 doi: 10.1016/j.yjmcc.2014.10.002
64
Bioactive Natural ProductsStudies in Natural Products Chemistry 2022; 75 doi: 10.1016/B978-0-323-91250-1.00004-5
65
Muwen Lu, Yong Cao, Jie Xiao, Mingyue Song, Chi-Tang Ho. Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a reviewFood & Function 2018; 9(9) doi: 10.1039/C8FO01349G
66
Richard Bedlack. ALSUntangled 44: curcuminAmyotrophic Lateral Sclerosis and Frontotemporal Degeneration 2018; 19(7-8) doi: 10.1080/21678421.2018.1440738
67
Behnam Ghorbani-nejad, Matin Baghani, Sajad Amiri, Nasim Agaei Delche, Mohammad Hossein Darijani, Motahareh Soltani, Alireza Nezami, Milad Rahimzadegan. Curcumin: multifaceted biological actions and therapeutic implications—a narrative reviewInflammopharmacology 2025; 33(11) doi: 10.1007/s10787-025-01932-6
68
Angélica Saraí Jiménez‐Osorio, Adriana Monroy, Silvestre Alavez. Curcumin and insulin resistance—Molecular targets and clinical evidencesBioFactors 2016; 42(6) doi: 10.1002/biof.1302
69
Hossein Bahari, Mostafa Shahraki Jazinaki, Zahra Asadi, Haniyeh Golafrouz. Curcumin/Turmeric Supplementation on Glycemic Control in Adults With Prediabetes and Type 2 Diabetes: A Systematic Review and Dose–Response Meta‐AnalysisFood Science & Nutrition 2026; 14(4) doi: 10.1002/fsn3.71748
70
Mona Alidadi, Amirhossein Sahebkar, Saeid Eslami, Farveh Vakilian, Lida Jarahi, Maryam Alinezhad-Namaghi, Seyed Mostafa Arabi, Saba Vakili, Fariba Tohidinezhad, Yasaman Nikooiyan, Abdolreza Norouzy. Pharmacological Properties of Plant-Derived Natural Products and Implications for Human HealthAdvances in Experimental Medicine and Biology 2021; 1308 doi: 10.1007/978-3-030-64872-5_1
71
Liyang Sun, Qi Zhao, Yao Xiao, Xuan Liu, Yumeng Li, Jingjing Zhang, Jiahui Pan, Zesheng Zhang. Trehalose targets Nrf2 signal to alleviate d-galactose induced aging and improve behavioral abilityBiochemical and Biophysical Research Communications 2020; 521(1) doi: 10.1016/j.bbrc.2019.10.088
72
Işın Çakır, Pauline Lining Pan, Colleen K Hadley, Abdulrahman El-Gamal, Amina Fadel, Dina Elsayegh, Omnia Mohamed, Nasser M Rizk, Masoud Ghamari-Langroudi. Sulforaphane reduces obesity by reversing leptin resistanceeLife 2022; 11 doi: 10.7554/eLife.67368
73
Morvarid Noormohammadi, Farzad Shidfar. Bioprospecting of Tropical Medicinal Plants2023;  doi: 10.1007/978-3-031-28780-0_46
74
Lizbeth Jiménez-Flores, Sergio López-Briones, Maciste Macías-Cervantes, Joel Ramírez-Emiliano, Victoriano Pérez-Vázquez. A PPARγ, NF-κB and AMPK-Dependent Mechanism May Be Involved in the Beneficial Effects of Curcumin in the Diabetic db/db Mice LiverMolecules 2014; 19(6) doi: 10.3390/molecules19068289
75
Maryam Teimouri, Hossein Hosseini, Maryam Shabani, Mehdi Koushki, Farshid Noorbakhsh, Reza Meshkani. Inhibiting miR‐27a and miR‐142‐5p attenuate nonalcoholic fatty liver disease by regulating Nrf2 signaling pathwayIUBMB Life 2020; 72(3) doi: 10.1002/iub.2221
76
Hiba Muwafaq Saleem, Hussein Riyadh Abdul Kareem Al-Hetty, Abdulrahman T. Ahmed, Muthanna M. Awad, Mohammed Qais Al-Ani, Mustafa Nuhad Al-Darraji, Dina Akeel Salman, Loay H. Ali. Effect of curcumin on lipid mediators, glycemic index, and oxidative stress and inflammation biomarkers in polycystic ovary syndrome: Future directions and current knowledge – A systematic reviewProstaglandins & Other Lipid Mediators 2025; 177 doi: 10.1016/j.prostaglandins.2024.106947
77
Monica Szabó, Beáta Máté, Katalin Csép, Theodora Benedek. Epigenetic Modifications Linked to T2D, the Heritability Gap, and Potential Therapeutic TargetsBiochemical Genetics 2018; 56(6) doi: 10.1007/s10528-018-9863-8
78
Ochuko L. Erukainure, Omamuyovwi M. Ijomone, Olajumoke A. Oyebode, Chika I. Chukwuma, Michael Aschner, Md. Shahidul Islam. Hyperglycemia-induced oxidative brain injury: Therapeutic effects of Cola nitida infusion against redox imbalance, cerebellar neuronal insults, and upregulated Nrf2 expression in type 2 diabetic ratsFood and Chemical Toxicology 2019; 127 doi: 10.1016/j.fct.2019.03.044
79
Yong Shi, Lei Zhong, Yuanxiang Liu, Shude Xu, Jihong Dai, Yaozhengtai Zhang, Yi Hu. Dietary sanguinarine supplementation recovers the decrease in muscle quality and nutrient composition induced by high-fat diets of grass carp (Ctenopharyngodon idella)Animal Nutrition 2024; 17 doi: 10.1016/j.aninu.2024.04.001
80
Dong Liu, Yanglin Ji, Yatu Guo, Hui Wang, Zijian Wu, Heyu Li, Hao Wang. Dietary Supplementation of Apple Phlorizin Attenuates the Redox State Related to Gut Microbiota Homeostasis in C57BL/6J Mice Fed with a High-Fat DietJournal of Agricultural and Food Chemistry 2021; 69(1) doi: 10.1021/acs.jafc.0c06426
81
Gözde Dumlu Bilgin, Nihal Büyükuslu, Ozan Emre Eyüpoğlu, Alev Cumbul. Co-administration of curcumin and polyamines in high-fat diet induced obese rats: Assessment of changes in serum polyamine levels and some tissue parametersProstaglandins & Other Lipid Mediators 2023; 169 doi: 10.1016/j.prostaglandins.2023.106784
82
Yaseen Hussain, Haroon Khan, Ghallab Alotaibi, Fazlullah Khan, Waqas Alam, Michael Aschner, Philippe Jeandet, Luciano Saso. How Curcumin Targets Inflammatory Mediators in Diabetes: Therapeutic Insights and Possible SolutionsMolecules 2022; 27(13) doi: 10.3390/molecules27134058
83
Anil Kumar, Ruchika Mittal. Nrf2: a potential therapeutic target for diabetic neuropathyInflammopharmacology 2017; 25(4) doi: 10.1007/s10787-017-0339-y
84
Susana Rivera-Mancía, Joyce Trujillo, José Pedraza Chaverri. Utility of curcumin for the treatment of diabetes mellitus: Evidence from preclinical and clinical studiesJournal of Nutrition & Intermediary Metabolism 2018; 14 doi: 10.1016/j.jnim.2018.05.001
85
Maryam Azhdari, Majid Karandish, Anahita Mansoori. Metabolic benefits of curcumin supplementation in patients with metabolic syndrome: A systematic review and meta‐analysis of randomized controlled trialsPhytotherapy Research 2019; 33(5) doi: 10.1002/ptr.6323
86
Matheus Correa-Costa, Leo E. Otterbein. Pharma-NutritionAAPS Advances in the Pharmaceutical Sciences Series 2014; 12 doi: 10.1007/978-3-319-06151-1_12
87
Akhlaq A. Farooqui. Therapeutic Potentials of Curcumin for Alzheimer Disease2016;  doi: 10.1007/978-3-319-15889-1_3
88
Sahdeo Prasad, Amit K. Tyagi, Bharat B. Aggarwal. Recent Developments in Delivery, Bioavailability, Absorption and Metabolism of Curcumin: the Golden Pigment from Golden SpiceCancer Research and Treatment 2014; 46(1) doi: 10.4143/crt.2014.46.1.2
89
Vivian Soetikno, Kenji Suzuki, Punniyakoti T. Veeraveedu, Somasundaram Arumugam, Arun P. Lakshmanan, Hirohito Sone, Kenichi Watanabe. Molecular understanding of curcumin in diabetic nephropathyDrug Discovery Today 2013; 18(15-16) doi: 10.1016/j.drudis.2013.04.009
90
Jean‐Marc Zingg, Syeda T. Hasan, Mohsen Meydani. Molecular mechanisms of hypolipidemic effects of curcuminBioFactors 2013; 39(1) doi: 10.1002/biof.1072
91
Yunfeng Gu, Yueping Chen, Rui Jin, Chao Wang, Chao Wen, Yanmin Zhou. Protective effects of curcumin on laying hens fed soybean meal with heat-induced protein oxidationItalian Journal of Animal Science 2021; 20(1) doi: 10.1080/1828051X.2021.1913653
92
Nagla El-Nabarawy, Ahmed Gouda, Ezzeldin Shalaby. Therapeutic Intervention of Curcumin on Interleukin-6 and Oxidative Stress Induced by Paraquat Toxicity of Lung and Liver in RatsBiomedical and Pharmacology Journal 2019; 12(04) doi: 10.13005/bpj/1803
93
Pattarawadee Taengthong, Ittipon Phoungpetchara, Onrawee Khongsombat, Sakara Tunsophon. Synergistic effects of curcumin and gamma-oryzanol solid dispersions ameliorate muscle atrophy by upregulating Nrf2 and IGF1/Insulin-Akt-mTOR activities in middle-aged ratsJournal of Functional Foods 2022; 99 doi: 10.1016/j.jff.2022.105318
94
Xiaoping Li, Liufeng Zheng, Bing Zhang, Ze-Yuan Deng, Ting Luo. The Structure Basis of Phytochemicals as Metabolic Signals for Combating ObesityFrontiers in Nutrition 2022; 9 doi: 10.3389/fnut.2022.913883
95
Wu-wen Feng, Shuang-yu Kuang, Can Tu, Zhi-jie Ma, Jing-yao Pang, Yan-hui Wang, Qing-ce Zang, Ta-si Liu, Yan-ling Zhao, Xiao-he Xiao, Jia-bo Wang. Natural products berberine and curcumin exhibited better ameliorative effects on rats with non-alcohol fatty liver disease than lovastatinBiomedicine & Pharmacotherapy 2018; 99 doi: 10.1016/j.biopha.2018.01.071
96
Sihle E. Mabhida, Phiwayinkosi V. Dludla, Rabia Johnson, Musawenkosi Ndlovu, Johan Louw, Andy R. Opoku, Rebamang A. Mosa. Protective effect of triterpenes against diabetes-induced β-cell damage: An overview of in vitro and in vivo studiesPharmacological Research 2018; 137 doi: 10.1016/j.phrs.2018.10.004
97
Mahsa Hatami, Mina Abdolahi, Neda Soveyd, Mahmoud Djalali, Mansoureh Togha, Niyaz Mohammadzadeh Honarvar. Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current EvidencesEndocrine, Metabolic & Immune Disorders - Drug Targets 2019; 19(3) doi: 10.2174/1871530319666181129103056
98
Shiri Li, Natsuki Eguchi, Hien Lau, Hirohito Ichii. The Role of the Nrf2 Signaling in Obesity and Insulin ResistanceInternational Journal of Molecular Sciences 2020; 21(18) doi: 10.3390/ijms21186973
99
Jéssica Gabriele da Silva Marques, Flavia Tasmin Techera Antunes, Lucimar Fillot da Silva Brum, Cláudia Pedron, Iasmine Berbigier de Oliveira, Alexandre de Barros Falcão Ferraz, Maria Isabel Morgan Martins, Eliane Dallegrave, Alessandra Hubner de Souza. Adaptogenic effects of curcumin on depression induced by moderate and unpredictable chronic stress in miceBehavioural Brain Research 2021; 399 doi: 10.1016/j.bbr.2020.113002
100
Akhilesh Kumar Sonakar, Attuluri Vamsi Kumar, Bipul Chandra Kalita, Vivek Kumar Garg, Harpal Singh Buttar, Dharambir Kashyap, Douglas W. Wilson. Biochemical Mechanisms for Metabolic SyndromeAdvances in Biochemistry in Health and Disease 2024; 31 doi: 10.1007/978-3-031-75686-3_15
101
Jin A Lee, Mi-Rae Shin, Ji Hye Lee, Seong-Soo Roh. The Effect of Chaenomelis Fructus Extract on Acute Hepatic Injury in RatsThe Journal of Internal Korean Medicine 2021; 42(1) doi: 10.22246/jikm.2021.42.1.1
102
Elżbieta Supruniuk, Marta Baczewska, Ewa Żebrowska, Mateusz Maciejczyk, Kamil Klaudiusz Lauko, Patrycja Dajnowicz-Brzezik, Patrycja Milewska, Paweł Knapp, Anna Zalewska, Adrian Chabowski. Redox Biomarkers and Matrix Remodeling Molecules in Ovarian CancerAntioxidants 2024; 13(2) doi: 10.3390/antiox13020200
103
Jozaa Z. ALTamimi, Nora A. AlFaris, Ammar M. AL-Farga, Ghedeir M. Alshammari, Mona N. BinMowyna, Mohammed A. Yahya. Curcumin reverses diabetic nephropathy in streptozotocin-induced diabetes in rats by inhibition of PKCβ/p66Shc axis and activation of FOXO-3aThe Journal of Nutritional Biochemistry 2021; 87 doi: 10.1016/j.jnutbio.2020.108515
104
Hu Liu, Lee J. Johnston, Fenglai Wang, Xi Ma. Triggers for the Nrf2/ARE Signaling Pathway and Its Nutritional Regulation: Potential Therapeutic Applications of Ulcerative ColitisInternational Journal of Molecular Sciences 2021; 22(21) doi: 10.3390/ijms222111411
105
Paolo Ria, Antonio De Pascalis, Anna Zito, Silvia Barbarini, Marcello Napoli, Antonietta Gigante, Gian Pio Sorice. Diet and Proteinuria: State of ArtInternational Journal of Molecular Sciences 2022; 24(1) doi: 10.3390/ijms24010044
106
Philip Newsholme, Vinicius Fernandes Cruzat, Kevin Noel Keane, Rodrigo Carlessi, Paulo Ivo Homem de Bittencourt. Molecular mechanisms of ROS production and oxidative stress in diabetesBiochemical Journal 2016; 473(24) doi: 10.1042/BCJ20160503C
107
Trinidad Eugenia Cu-Cañetas, Laura A. Velázquez-Villegas, Mariana Manzanilla-Franco, Teresa del Rosario Ayora-Talavera, Juan José Acevedo-Fernández, Enrique Barbosa-Martín, Claudia C. Márquez-Mota, Adriana M. López-Barradas, Lilia G. Noriega, Martha Guevara-Cruz, Ana Ligia Gutiérrez-Solís, Azalia Avila-Nava. Ramon Flour (Brosimum alicastrum Swartz) Ameliorates Hepatic Lipid Accumulation, Induction of AMPK Phosphorylation, and Expression of the Hepatic Antioxidant System in a High-Fat-Diet-Induced Obesity Mouse ModelAntioxidants 2023; 12(11) doi: 10.3390/antiox12111957
108
Adeeb Shehzad, Munibah Qureshi, Muhammad Nabeel Anwar, Young Sup Lee. Multifunctional Curcumin Mediate Multitherapeutic EffectsJournal of Food Science 2017; 82(9) doi: 10.1111/1750-3841.13793
109
Beatriz Moreira-Pinto, Lia Costa, Bruno M Fonseca, Irene Rebelo. Dissimilar effects of curcumin on human granulosa cells: Beyond its anti-oxidative roleReproductive Toxicology 2020; 95 doi: 10.1016/j.reprotox.2020.04.069
110
Da-Yeon Lee, Yoon-Seok Chun, Jong-Kyu Kim, Jeong-Ok Lee, Sae-Kwang Ku, Soon-Mi Shim. Curcumin Attenuates Sarcopenia in Chronic Forced Exercise Executed Aged Mice by Regulating Muscle Degradation and Protein Synthesis with Antioxidant and Anti-inflammatory EffectsJournal of Agricultural and Food Chemistry 2021; 69(22) doi: 10.1021/acs.jafc.1c00699
111
Denise Mafra, Eva‐Karin Gidlund, Natália Alvarenga Borges, D'Angelo Carlo Magliano, Bengt Lindholm, Peter Stenvinkel, Ferdinand von Walden. Bioactive food and exercise in chronic kidney disease: Targeting the mitochondriaEuropean Journal of Clinical Investigation 2018; 48(11) doi: 10.1111/eci.13020
112
Ndivhuwo Muvhulawa, Sithandiwe E. Mazibuko-Mbeje, Duduzile Ndwandwe, Sonia Silvestri, Khanyisani Ziqubu, Marakiya T. Moetlediwa, Sinenhlanhla X.H. Mthembu, Jeanine L. Marnewick, Francois H. Van der Westhuizen, Bongani B. Nkambule, Albertus K. Basson, Luca Tiano, Phiwayinkosi V. Dludla. Sarcopenia in a type 2 diabetic state: Reviewing literature on the pathological consequences of oxidative stress and inflammation beyond the neutralizing effect of intracellular antioxidantsLife Sciences 2023; 332 doi: 10.1016/j.lfs.2023.122125
113
Kenichiro Takano, Junko Tatebe, Naohiro Washizawa, Toshisuke Morita. Curcumin Inhibits Age-Related Vascular Changes in Aged Mice Fed a High-Fat DietNutrients 2018; 10(10) doi: 10.3390/nu10101476
114
Klinsmann Carolo dos Santos, Bianca Guerra Bueno, Luana Ferreira Pereira, Fabiane Valentini Francisqueti, Mariana Gobbo Braz, Lahis Fernandes Bincoleto, Lilian Xavier da Silva, Ana Lúcia A. Ferreira, Ana Cláudia de Melo Stevanato Nakamune, C.-Y. Oliver Chen, Jeffrey B. Blumberg, Camila Renata Corrêa, Luigi Milella. Yacon (Smallanthus sonchifolius) Leaf Extract Attenuates Hyperglycemia and Skeletal Muscle Oxidative Stress and Inflammation in Diabetic RatsEvidence-Based Complementary and Alternative Medicine 2017; 2017(1) doi: 10.1155/2017/6418048
115
Israel Pérez-Torres, Vicente Castrejón-Téllez, María Elena Soto, María Esther Rubio-Ruiz, Linaloe Manzano-Pech, Verónica Guarner-Lans. Oxidative Stress, Plant Natural Antioxidants, and ObesityInternational Journal of Molecular Sciences 2021; 22(4) doi: 10.3390/ijms22041786
116
Jorge Gutiérrez-Cuevas, Marina Galicia-Moreno, Hugo Christian Monroy-Ramírez, Ana Sandoval-Rodriguez, Jesús García-Bañuelos, Arturo Santos, Juan Armendariz-Borunda. The Role of NRF2 in Obesity-Associated Cardiovascular Risk FactorsAntioxidants 2022; 11(2) doi: 10.3390/antiox11020235
117
Emanuela Mhillaj, Andrea Tarozzi, Letizia Pruccoli, Vincenzo Cuomo, Luigia Trabace, Cesare Mancuso. Curcumin and Heme Oxygenase: Neuroprotection and BeyondInternational Journal of Molecular Sciences 2019; 20(10) doi: 10.3390/ijms20102419
118
Emiliano Panieri, Aleksandra Buha, Pelin Telkoparan-Akillilar, Dilek Cevik, Demetrios Kouretas, Aristidis Veskoukis, Zoi Skaperda, Aristidis Tsatsakis, David Wallace, Sibel Suzen, Luciano Saso. Potential Applications of NRF2 Modulators in Cancer TherapyAntioxidants 2020; 9(3) doi: 10.3390/antiox9030193
119
Adeeb Shehzad, Gauhar Rehman, Young Sup Lee. Curcumin in inflammatory diseasesBioFactors 2013; 39(1) doi: 10.1002/biof.1066
120
Dong-wei Zhang, Min Fu, Si-Hua Gao, Jun-Li Liu. Curcumin and Diabetes: A Systematic ReviewEvidence-Based Complementary and Alternative Medicine 2013; 2013 doi: 10.1155/2013/636053
121
Habib Yaribeygi, Thozhukat Sathyapalan, Tannaz Jamialahmadi, Amirhossein Sahebkar. Natural Products and Human DiseasesAdvances in Experimental Medicine and Biology 2021; 1328 doi: 10.1007/978-3-030-73234-9_26
122
Milad Ashrafizadeh, Zahra Ahmadi, Reza Mohammadinejad, Tahereh Farkhondeh, Saeed Samarghandian. Curcumin Activates the Nrf2 Pathway and Induces Cellular Protection Against Oxidative InjuryCurrent Molecular Medicine 2020; 20(2) doi: 10.2174/1566524019666191016150757
123
Mi-Bo Kim, Jaeeun Lee, Ji-Young Lee. Targeting Mitochondrial Dysfunction for the Prevention and Treatment of Metabolic Disease by Bioactive Food ComponentsJournal of Lipid and Atherosclerosis 2024; 13(3) doi: 10.12997/jla.2024.13.3.306
124
Sabri Sudirman, Ching-Shu Lai, Yi-Ling Yan, Hung-I Yeh, Zwe-Ling Kong. Histological evidence of chitosan-encapsulated curcumin suppresses heart and kidney damages on streptozotocin-induced type-1 diabetes in mice modelScientific Reports 2019; 9(1) doi: 10.1038/s41598-019-51821-6
125
Karoline Felisbino, Juliano Gomes Granzotti, Larissa Bello-Santos, Izonete Cristina Guiloski. Nutrigenomics in Regulating the Expression of Genes Related to Type 2 Diabetes MellitusFrontiers in Physiology 2021; 12 doi: 10.3389/fphys.2021.699220
126
Agnieszka Łoboda, Józef Dulak. Nuclear Factor Erythroid 2-Related Factor 2 and Its Targets in Skeletal Muscle Repair and RegenerationAntioxidants & Redox Signaling 2023; 38(7-9) doi: 10.1089/ars.2022.0208
127
Md. Fahim Ahmad, Inamur Rahman, Nida Naseem, Nazia Imam, Hina Younus, Haseeb Ahsan, Waseem A. Siddiqui. Therapeutic Potential of Phenolic Phytochemicals in Diabetes MellitusResonance 2024; 29(10) doi: 10.1007/s12045-024-1389-2
128
Mingyu Duan, Zhiting Zhu, Hao Pi, Jibing Chen, Jie Cai, Yiping Wu. Mechanistic Insights and Analytical Advances in Food Antioxidants: A Comprehensive Review of Molecular Pathways, Detection Technologies, and Nutritional ApplicationsAntioxidants 2025; 14(4) doi: 10.3390/antiox14040438
129
Alejandra Espinosa, Carlos Henríquez-Olguín, Enrique Jaimovich. Reactive oxygen species and calcium signals in skeletal muscle: A crosstalk involved in both normal signaling and diseaseCell Calcium 2016; 60(3) doi: 10.1016/j.ceca.2016.02.010
130
Noha Ahmed Nasef, Peter Zhu, Matt Golding, Anant Dave, Ajmol Ali, Harjinder Singh, Manohar Garg. Salmon food matrix influences digestion and bioavailability of long-chain omega-3 polyunsaturated fatty acidsFood & Function 2021; 12(14) doi: 10.1039/D1FO00475A
131
Faiz-ul Hassan, Muhammad Saif-ur Rehman, Muhammad Sajjad Khan, Muhammad Amjad Ali, Aroosa Javed, Ayesha Nawaz, Chengjian Yang. Curcumin as an Alternative Epigenetic Modulator: Mechanism of Action and Potential EffectsFrontiers in Genetics 2019; 10 doi: 10.3389/fgene.2019.00514
132
Gaurav Kumar, Sonam Mittal, Katrin Sak, Hardeep Singh Tuli. Molecular mechanisms underlying chemopreventive potential of curcumin: Current challenges and future perspectivesLife Sciences 2016; 148 doi: 10.1016/j.lfs.2016.02.022
133
Belén Pastor-Villaescusa, Estefania Sanchez Rodriguez, Oscar D. Rangel-Huerta. Obesity2018;  doi: 10.1016/B978-0-12-812504-5.00011-8
134
Gopal Lamichhane, Jing Liu, Su-Jeong Lee, Da-Yeon Lee, Guolong Zhang, Yoo Kim. Curcumin Mitigates the High-Fat High-Sugar Diet-Induced Impairment of Spatial Memory, Hepatic Metabolism, and the Alteration of the Gut Microbiome in Alzheimer’s Disease-Induced (3xTg-AD) MiceNutrients 2024; 16(2) doi: 10.3390/nu16020240
135
Ochuko L. Erukainure, Omamuyovwi M. Ijomone, Olakunle Sanni, Michael Aschner, Md. Shahidul Islam. Type 2 diabetes induced oxidative brain injury involves altered cerebellar neuronal integrity and elemental distribution, and exacerbated Nrf2 expression: therapeutic potential of raffia palm (Raphia hookeri) wineMetabolic Brain Disease 2019; 34(5) doi: 10.1007/s11011-019-00444-x
136
Lili Ding, Jinmei Li, Baoliang Song, Xu Xiao, Binfeng Zhang, Meng Qi, Wendong Huang, Li Yang, Zhengtao Wang. Curcumin rescues high fat diet-induced obesity and insulin sensitivity in mice through regulating SREBP pathwayToxicology and Applied Pharmacology 2016; 304 doi: 10.1016/j.taap.2016.05.011
137
Katy Thouvenot, Teva Turpin, Janice Taïlé, Karine Clément, Olivier Meilhac, Marie-Paule Gonthier. Links between Insulin Resistance and Periodontal Bacteria: Insights on Molecular Players and Therapeutic Potential of PolyphenolsBiomolecules 2022; 12(3) doi: 10.3390/biom12030378
138
Betsy Cogan, Regis C. Pearson, Nathan T. Jenkins, Chad M. Paton, Jamie A. Cooper. A 4-Week Pecan-Enriched Diet Improves Postprandial Lipid Peroxidation in Aging AdultsJournal of Medicinal Food 2023; 26(9) doi: 10.1089/jmf.2023.0036
139
Joo Wan Kim, Sae-Kwang Ku, Ki Young Kim, Sung Goo Kim, Min Ho Han, Gi-Young Kim, Hye Jin Hwang, Byung Woo Kim, Cheol Min Kim, Yung Hyun Choi. Schisandrae Fructus Supplementation Ameliorates Sciatic Neurectomy-Induced Muscle Atrophy in MiceOxidative Medicine and Cellular Longevity 2015; 2015 doi: 10.1155/2015/872428
140
Tian-ru Jin. Curcumin and dietary polyphenol research: beyond drug discoveryActa Pharmacologica Sinica 2018; 39(5) doi: 10.1038/aps.2017.179
141
Negin Parsamanesh, Maryam Moossavi, Afsane Bahrami, Alexandra E. Butler, Amirhossein Sahebkar. Therapeutic potential of curcumin in diabetic complicationsPharmacological Research 2018; 136 doi: 10.1016/j.phrs.2018.09.012
142
Godwin Anywar, Adeyinka O. Adepoju, Bruhan Kaggwa, Nillian A. Mukungu. Antidiabetic Drug Discovery from Natural Products2025;  doi: 10.1016/B978-0-443-30086-8.00001-2
143
Philip Newsholme, Kevin N. Keane, Rodrigo Carlessi, Vinicius Cruzat. Oxidative stress pathways in pancreatic β-cells and insulin-sensitive cells and tissues: importance to cell metabolism, function, and dysfunctionAmerican Journal of Physiology-Cell Physiology 2019; 317(3) doi: 10.1152/ajpcell.00141.2019
144
Liyi Wang, Ziye Xu, Defeng Ling, Jie Li, Yizhen Wang, Tizhong Shan. The regulatory role of dietary factors in skeletal muscle development, regeneration and functionCritical Reviews in Food Science and Nutrition 2022; 62(3) doi: 10.1080/10408398.2020.1828812
145
Pabitra B. Pal, Shatadal Ghosh, Parames C. Sil. Bioactive Natural Products2014;  doi: 10.1002/9783527684403.ch8
146
Sae-Kwang Ku, Jong-Min Lim, Hyung-Rae Cho, Khawaja Muhammad Imran Bashir, Young Suk Kim, Jae-Suk Choi. Tart Cherry (Fruit of Prunus cerasus) Concentrated Powder (TCcp) Ameliorates Glucocorticoid-Induced Muscular Atrophy in MiceMedicina 2021; 57(5) doi: 10.3390/medicina57050485
147
Lu Wang, Weiyun Zheng, Qiuyue Men, Xiaomeng Ren, Shuang Song, Chunqing Ai. Curcumin-loaded polysaccharide microparticles alleviated DSS-induced ulcerative colitis by improving intestinal microecology and regulating MAPK/NF-κB/Nrf2/NLRP3 pathwaysInternational Journal of Biological Macromolecules 2024; 281 doi: 10.1016/j.ijbiomac.2024.136687
148
Danja J. Den Hartogh, Alessandra Gabriel, Evangelia Tsiani. Antidiabetic Properties of Curcumin II: Evidence from In Vivo StudiesNutrients 2019; 12(1) doi: 10.3390/nu12010058
149
Dingya Sun, Jialu Wang, Xin Li, Jun Peng, Shan Wang. Advances and Perspectives in Curcumin Regulation of Systemic Metabolism: A Focus on Multi-Organ MechanismsAntioxidants 2026; 15(1) doi: 10.3390/antiox15010109
150
Arnold N. Onyango, Claudio Cabello-Verrugio. Cellular Stresses and Stress Responses in the Pathogenesis of Insulin ResistanceOxidative Medicine and Cellular Longevity 2018; 2018(1) doi: 10.1155/2018/4321714
151
Ashish Shah, Vaishali Patel, Ghanshyam Parmar. Phytoantioxidants and Nanotherapeutics2022;  doi: 10.1002/9781119811794.ch22
152
Kang Cheng, Zhihua Song, Hao Zhang, Simian Li, Chao Wang, Lili Zhang, Tian Wang. The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expressionMedical Molecular Morphology 2019; 52(4) doi: 10.1007/s00795-019-00216-7
153
Iurii Koboziev, Shane Scoggin, Xiaoxia Gong, Parvin Mirzaei, Masoud Zabet-Moghaddam, Mohammad Yosofvand, Hanna Moussa, Yava Jones-Hall, Naima Moustaid-Moussa. Effects of Curcumin in a Mouse Model of Very High Fat Diet-Induced ObesityBiomolecules 2020; 10(10) doi: 10.3390/biom10101368
154
Sithandiwe Eunice Mazibuko-Mbeje, Phiwayinkosi V. Dludla, Bongani B. Nkambule, Nnini Obonye, Johan Louw. Muscle Cell and Tissue - Current Status of Research Field2018;  doi: 10.5772/intechopen.78687
155
Gina P. Rodriguez-Castaño, Alejandro Caro-Quintero, Alejandro Reyes, Fernando Lizcano. Advances in Gut Microbiome Research, Opening New Strategies to Cope with a Western LifestyleFrontiers in Genetics 2017; 7 doi: 10.3389/fgene.2016.00224
156
Fang Liu, Zhaojie Li, Binbin Cao, Juan Wu, Yuming Wang, Yong Xue, Jie Xu, Changhu Xue, Qing Juan Tang. The effect of a novel photodynamic activation method mediated by curcumin on oyster shelf life and qualityFood Research International 2016; 87 doi: 10.1016/j.foodres.2016.07.012
157
Ochuko L. Erukainure, Omamuyovwi M. Ijomone, Chika I. Chukwuma, Xin Xiao, Veronica F. Salau, Md Shahidul Islam. Dacryodes edulis (G. Don) H.J. Lam modulates glucose metabolism, cholinergic activities and Nrf2 expression, while suppressing oxidative stress and dyslipidemia in diabetic ratsJournal of Ethnopharmacology 2020; 255 doi: 10.1016/j.jep.2020.112744
158
Candace N. Receno, Chen Liang, Donna L. Korol, Mustafa Atalay, Kevin S. Heffernan, Tom D. Brutsaert, Keith C. DeRuisseau. Effects of Prolonged Dietary Curcumin Exposure on Skeletal Muscle Biochemical and Functional Responses of Aged Male RatsInternational Journal of Molecular Sciences 2019; 20(5) doi: 10.3390/ijms20051178
159
Yuanyuan Qian, Peng Zhong, Dandan Liang, Zheng Xu, Melissa Skibba, Chunlai Zeng, Xiaokun Li, Tiemin Wei, Lianpin Wu, Guang Liang, Partha Mukhopadhyay. A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese RatsPLOS ONE 2015; 10(3) doi: 10.1371/journal.pone.0120215
160
N. E. Sharanova, A. V. Vasil’ev. Postgenomic Properties of Natural MicronutrientsBulletin of Experimental Biology and Medicine 2018; 166(1) doi: 10.1007/s10517-018-4298-0
161
Saumik Biswas, Shali Chen, Guang Liang, Biao Feng, Lu Cai, Zia A. Khan, Subrata Chakrabarti. Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of DiabetesFrontiers in Endocrinology 2019; 10 doi: 10.3389/fendo.2019.00887
162
Vivian Soetikno, Flori R. Sari, Arun P. Lakshmanan, Somasundaram Arumugam, Meilei Harima, Kenji Suzuki, Hiroshi Kawachi, Kenichi Watanabe. Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2–keap1 pathwayMolecular Nutrition & Food Research 2013; 57(9) doi: 10.1002/mnfr.201200540
163
Da-Yeon Lee, Su-Jeong Lee, Prabha Chandrasekaran, Gopal Lamichhane, Jennifer F. O’Connell, Josephine M. Egan, Yoo Kim. Dietary Curcumin Attenuates Hepatic Cellular Senescence by Suppressing the MAPK/NF-κB Signaling Pathway in Aged MiceAntioxidants 2023; 12(6) doi: 10.3390/antiox12061165
164
Javad Heshmati, Ashraf Moini, Mahdi Sepidarkish, Mojgan Morvaridzadeh, Masoud Salehi, Andriko Palmowski, Maryam Farid Mojtahedi, Farzad Shidfar. Effects of curcumin supplementation on blood glucose, insulin resistance and androgens in patients with polycystic ovary syndrome: A randomized double-blind placebo-controlled clinical trialPhytomedicine 2021; 80 doi: 10.1016/j.phymed.2020.153395
165
Nrarat Chobsuay, Pennapa Chonpathompikunlert, Jukkarin Srivilai, Wachirawadee Malakul, Nanteetip Limpeanchob, Sathid Aimjongjun, Sakara Tunsophon, Chan-Yen Kuo. Passiflora edulis f. flavicarpa Extract Prevents Muscle Atrophy and Insulin Resistance in High‐Fat Diet–Induced Obese Rats via Regulating the Nrf2, NF‐κB, and IRS‐1/PI3K/AKT Signaling PathwaysOxidative Medicine and Cellular Longevity 2026; 2026(1) doi: 10.1155/omcl/5709962
166
Meng‐Chen Lu, Jian‐Ai Ji, Zheng‐Yu Jiang, Qi‐Dong You. The Keap1–Nrf2–ARE Pathway As a Potential Preventive and Therapeutic Target: An UpdateMedicinal Research Reviews 2016; 36(5) doi: 10.1002/med.21396
167
Jong‑Min Lim, Young Joon Lee, Hyung‑Rae Cho, Dong‑Chan Park, Go‑Woon Jung, Sae Kwang Ku, Jae‑Suk Choi. Extracellular polysaccharides purified from Aureobasidium pullulans SM‑2001 (Polycan) inhibit dexamethasone‑induced muscle atrophy in miceInternational Journal of Molecular Medicine 2017;  doi: 10.3892/ijmm.2017.3251
168
Z.X. Xie, S.F. Xia, Y. Qiao, Y.H. Shi, G.W. Le. Effect of GABA on oxidative stress in the skeletal muscles and plasma free amino acids in mice fed high‐fat dietJournal of Animal Physiology and Animal Nutrition 2015; 99(3) doi: 10.1111/jpn.12254
169
Se Hui Lee, Min Ju Kim, Mi-Rae Shin, Bold Sharav, Hae-Jin Park, Seong-Soo Roh. Efficacy Evaluation of Pinus sylvestris var. mongolica on Mice with Gastric Ulcers Induced by 150 mM HCl/60% EthanolJournal of the Korean Society of Food Science and Nutrition 2022; 51(3) doi: 10.3746/jkfn.2022.51.3.195
170
Hanaa H. Ahmed, Soheir E. Kotob, Ahmed A. Abd-Rabou, Hadeer A. Aglan, Gamal A. Elmegeed. Pre-Clinical Evidence for the Anti-Obesity Potential of Quercetin and Curcumin Loaded Chitosan/PEG Blended PLGA NanoparticlesBiomedical and Pharmacology Journal 2021; 14(4) doi: 10.13005/bpj/2274
171
Ochuko L. Erukainure, Olajumoke A. Oyebode, Omamuyovwi M. Ijomone, Chika I. Chukwuma, Neil A. Koorbanally, Md. Shahidul Islam. Raffia palm (Raphia hookeri G. Mann & H. Wendl) wine modulates glucose homeostasis by enhancing insulin secretion and inhibiting redox imbalance in a rat model of diabetes induced by high fructose diet and streptozotocinJournal of Ethnopharmacology 2019; 237 doi: 10.1016/j.jep.2019.03.039
172
Seo-Hyuk Chang, Jeong-Soo Lee, Ui Jeong Yun, Kye Won Park. A Role of Stress Sensor Nrf2 in Stimulating Thermogenesis and Energy ExpenditureBiomedicines 2021; 9(9) doi: 10.3390/biomedicines9091196
173
Bao-Hong Lee, Tzu-Ming Pan. Dimerumic acid, a novel antioxidant identified from Monascus-fermented products exerts chemoprotective effects: Mini reviewJournal of Functional Foods 2013; 5(1) doi: 10.1016/j.jff.2012.11.009
174
Min Young Um, Kwang Hyun Hwang, Jiyun Ahn, Tae Youl Ha. Curcumin Attenuates Diet‐Induced Hepatic Steatosis by Activating AMP‐Activated Protein KinaseBasic & Clinical Pharmacology & Toxicology 2013; 113(3) doi: 10.1111/bcpt.12076
175
Daniela Maria Tanase, Evelina Maria Gosav, Madalina Ioana Anton, Mariana Floria, Petronela Nicoleta Seritean Isac, Loredana Liliana Hurjui, Claudia Cristina Tarniceriu, Claudia Florida Costea, Manuela Ciocoiu, Ciprian Rezus. Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New PerspectivesBiomolecules 2022; 12(9) doi: 10.3390/biom12091227
176
Dehua Liao, Danggang Shangguan, Yi Wu, Yun Chen, Ni Liu, Jingyi Tang, Dunwu Yao, Yingrui Shi. Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathwaysPsychopharmacology 2023; 240(5) doi: 10.1007/s00213-023-06357-z
177
Hyun-Ae Seo, In-Kyu Lee. The Role of Nrf2: Adipocyte Differentiation, Obesity, and Insulin ResistanceOxidative Medicine and Cellular Longevity 2013; 2013 doi: 10.1155/2013/184598
178
Sarandeep S. S. Boyanapalli, Ah- Ng Tony Kong. “Curcumin, the King of Spices”: Epigenetic Regulatory Mechanisms in the Prevention of Cancer, Neurological, and Inflammatory DiseasesCurrent Pharmacology Reports 2015; 1(2) doi: 10.1007/s40495-015-0018-x
179
Gagan Prakash, Anis Ahmad Chaudhary, Ruchita Tanu, Mohamed A. M. Ali, Fehmi Boufahja, Pushpender K. Sharma, Sudarshan Singh Lakhawat, Tejpal Yadav, Navneet Kumar Upadhyay, Vikram Kumar. Harnessing Phytochemicals and Nanotechnology Synergy for Molecular, Epigenetic, and Microbiota-Driven Regulation in Type 2 Diabetes MellitusPharmaceutics 2026; 18(1) doi: 10.3390/pharmaceutics18010113
180
Muthu Thiruvengadam, Baskar Venkidasamy, Umadevi Subramanian, Ramkumar Samynathan, Mohammad Ali Shariati, Maksim Rebezov, Shabari Girish, Sivakumar Thangavel, Anand Raj Dhanapal, Natalya Fedoseeva, Joohyun Lee, Ill-Min Chung. Bioactive Compounds in Oxidative Stress-Mediated Diseases: Targeting the NRF2/ARE Signaling Pathway and Epigenetic RegulationAntioxidants 2021; 10(12) doi: 10.3390/antiox10121859
181
Elango Bhakkiyalakshmi, Dornadula Sireesh, Palanisamy Rajaguru, Ramasamy Paulmurugan, Kunka Mohanram Ramkumar. The emerging role of redox-sensitive Nrf2–Keap1 pathway in diabetesPharmacological Research 2015; 91 doi: 10.1016/j.phrs.2014.10.004
182
Juan Carlos Solís‐S, Pablo García‐Solís, Ludivina Robles‐Osorio, Hebert Luis Hernández‐Montiel. Fruit and Vegetable Phytochemicals2017;  doi: 10.1002/9781119158042.ch3
183
Peng Hui, Xianrui Zheng, Jiao Dong, Fan Lu, Chao Xu, Huan Qu, Xiaoyang Zhu, Yoshinobu Uemoto, Xiaoyang Lv, Zongjun Yin, Wei Sun, Wenbin Bao, Haifei Wang. Metabolomics and Transcriptomics Analyses of Curcumin Alleviation of Ochratoxin A-Induced HepatotoxicityInternational Journal of Molecular Sciences 2023; 25(1) doi: 10.3390/ijms25010168
184
Liwei Ren, Ping Zhan, Qi Wang, Cuixue Wang, Yongnian Liu, Zhiwen Yu, Shuangshuang Zhang. Curcumin upregulates the Nrf2 system by repressing inflammatory signaling-mediated Keap1 expression in insulin-resistant conditionsBiochemical and Biophysical Research Communications 2019; 514(3) doi: 10.1016/j.bbrc.2019.05.010
185
Caroline Bertoncini Silva, Priscila Giacomo Fassini, Leandra Náira Zambelli Ramalho, Edemilson Cardoso da Conceição, Aline José Coelho Moreira Zordan, Daniela Carlos, Vivian Marques Miguel Suen. Curcuma supplementation in high-fat-fed C57BL/6 mice: no beneficial effect on lipid and glucose profile or prevention of weight gainEuropean Journal of Nutrition 2020; 59(1) doi: 10.1007/s00394-018-1887-7
186
Xin Cheng, Yejun Tan, Hongli Li, Zhen Zhang, Shan Hui, Zheyu Zhang, Weijun Peng. Mechanistic Insights and Potential Therapeutic Implications of NRF2 in Diabetic EncephalopathyMolecular Neurobiology 2024; 61(10) doi: 10.1007/s12035-024-04097-5
187
Huijuan Zhang, Rui Kang, Tiancong Song, Feiyue Ren, Jie Liu, Jing Wang. Advances in relieving exercise fatigue for curcumin: Molecular targets, bioavailability, and potential mechanismJournal of Food Science 2024; 89(8) doi: 10.1111/1750-3841.17162
188
Miaomiao Lu, Nanchang Yin, Wei Liu, Xiangfei Cui, Shuo Chen, Ermin Wang. Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome SignalingBioMed Research International 2017; 2017 doi: 10.1155/2017/1516985
189
Yuhei Mizunoe, Masaki Kobayashi, Yuka Sudo, Shukoh Watanabe, Hiromine Yasukawa, Daiki Natori, Ayana Hoshino, Arisa Negishi, Naoyuki Okita, Masaaki Komatsu, Yoshikazu Higami. Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathwaysRedox Biology 2018; 15 doi: 10.1016/j.redox.2017.09.007
190
Yudong Xia, Xiaoying Zhai, Yanning Qiu, Xuemei Lu, Yi Jiao. The Nrf2 in Obesity: A Friend or Foe?Antioxidants 2022; 11(10) doi: 10.3390/antiox11102067
191
Zi-yu Zhou, Li-wei Ren, Ping Zhan, Han-yan Yang, Dan-dan Chai, Zhi-wen Yu. Metformin exerts glucose-lowering action in high-fat fed mice via attenuating endotoxemia and enhancing insulin signalingActa Pharmacologica Sinica 2016; 37(8) doi: 10.1038/aps.2016.21
192
Marzena Wojcik, Michal Krawczyk, Lucyna A. Wozniak. Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome2018;  doi: 10.1016/B978-0-12-812019-4.00031-3
193
Fang Wan, Lixuan Tang, Gan Rao, Gaolong Zhong, Xuanxuan Jiang, Shaofeng Wu, Riming Huang, Zhaoxin Tang, Zhiyan Ruan, Zhongwei Chen, Lianmei Hu. Curcumin activates the Nrf2 Pathway to alleviate AFB1-induced immunosuppression in the spleen of ducklingsToxicon 2022; 209 doi: 10.1016/j.toxicon.2022.01.010
194
Mahdie Rahban, Mehran Habibi-Rezaei, Mansoureh Mazaheri, Luciano Saso, Ali A. Moosavi-Movahedi. Anti-Viral Potential and Modulation of Nrf2 by Curcumin: Pharmacological ImplicationsAntioxidants 2020; 9(12) doi: 10.3390/antiox9121228
195
Alison D. McNeilly, Jennifer R. Gallagher, Albena T. Dinkova-Kostova, John D. Hayes, John Sharkey, Michael L.J. Ashford, Rory J. McCrimmon. Nrf2-Mediated Neuroprotection Against Recurrent Hypoglycemia Is Insufficient to Prevent Cognitive Impairment in a Rodent Model of Type 1 DiabetesDiabetes 2016; 65(10) doi: 10.2337/db15-1653
196
Mohammad Alizadeh, Sorayya Kheirouri. Curcumin reduces malondialdehyde and improves antioxidants in humans with diseased conditions: a comprehensive meta-analysis of randomized controlled trialsBioMedicine 2019; 9(4) doi: 10.1051/bmdcn/2019090423
197
Seyed Hossein Shahcheraghi, Fateme Salemi, Niloufar Peirovi, Jamshid Ayatollahi, Waqas Alam, Haroon Khan, Luciano Saso. Nrf2 Regulation by Curcumin: Molecular Aspects for Therapeutic ProspectsMolecules 2021; 27(1) doi: 10.3390/molecules27010167
198
Lili Tian, Kejing Zeng, Weijuan Shao, Burton B Yang, I George Fantus, Jianping Weng, Tianru Jin. Short-Term Curcumin Gavage Sensitizes Insulin Signaling in Dexamethasone-Treated C57BL/6 MiceThe Journal of Nutrition 2015; 145(10) doi: 10.3945/jn.115.216853
199
Sevda Tanrıkulu-Küçük, Canan Başaran-Küçükgergin, Muhammed Seyithanoğlu, Semra Doğru-Abbasoğlu, Hikmet Koçak, Şule Beyhan-Özdaş, Yıldız Öner-İyidoğan. Effect of dietary curcumin and capsaicin on testicular and hepatic oxidant–antioxidant status in rats fed a high-fat dietApplied Physiology, Nutrition, and Metabolism 2019; 44(7) doi: 10.1139/apnm-2018-0622
200
Maria M. Bayliak, Oleksandra B. Abrat. Nrf2 and its Modulation in InflammationProgress in Inflammation Research 2020; 85 doi: 10.1007/978-3-030-44599-7_7
201
Adeeb Shehzad, Young Sup Lee. Molecular mechanisms of curcumin action: Signal transductionBioFactors 2013; 39(1) doi: 10.1002/biof.1065
202
Ilker Ates, Ayşe Didem Yılmaz, Brigitta Buttari, Marzia Arese, Luciano Saso, Sibel Suzen. A Review of the Potential of Nuclear Factor [Erythroid-Derived 2]-like 2 Activation in Autoimmune DiseasesBrain Sciences 2023; 13(11) doi: 10.3390/brainsci13111532
203
Solomon Habtemariam. Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases2019;  doi: 10.1016/B978-0-08-102922-0.00020-1
204
Shaun A. Mason, Adam J. Trewin, Lewan Parker, Glenn D. Wadley. Antioxidant supplements and endurance exercise: Current evidence and mechanistic insightsRedox Biology 2020; 35 doi: 10.1016/j.redox.2020.101471