Thornley P, Al Beshir M, Gregor J, Antoniou A, Khanna N. Efficiency and patient experience with propofol vs conventional sedation: A prospective study. World J Gastrointest Endosc 2016; 8(4): 232-238 [PMID: 26962405 DOI: 10.4253/wjge.v8.i4.232]
Corresponding Author of This Article
Nitin Khanna, MD, Division of Gastroenterology, Western University, 529 McGarrell Place, London, Ontario N6A 3K7, Canada. nitin.khanna@sjhc.london.on.ca
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Feb 25, 2016; 8(4): 232-238 Published online Feb 25, 2016. doi: 10.4253/wjge.v8.i4.232
Table 1 Participants’ demographics for endoscopist-administered sedation and anaesthesiologist-administered sedation with propofol groups n (%)
EAC (n = 104)
AAP (n = 126)
P-value
Male sex - frequency
60 (57.7)
46 (36.5)
0.001
Age
59.8 (11.6)
57.1 (13.3)
0.101
Weight
183.3 (49.1)
174.6 (46.5)
0.169
Height
67.6 (4.2)
66.3 (4.0)
0.016
BMI
28.0 (6.5)
27.7 (6.2)
0.750
Indication - symptomatic
33 (31.7)
55 (43.7)
0.064
Intervention
0.936
None
31 (29.8)
37 (29.4)
Diagnostic
25 (24.0)
34 (27.0)
Therapeutic
36 (34.6)
43 (34.1)
Diagnostic and therapeutic
12 (11.5)
12 (9.5)
ASA class
0.089
1
42 (40.4)
52 (41.3)
2
54 (51.9)
53 (42.1)
3
8 (7.7)
21 (16.7)
Table 2 Multivariate analysis of procedure measurables
Coefficient
P-value
BMI
-0.008
0.008
ASA class
0.066
0.016
Intervention - diagnostic
0.084
0.033
Intervention - therapeutic
0.246
< 0.001
Propofol sedation (AAP)
0.091
0.002
Resident involved
0.391
< 0.001
Table 3 Procedure time and total procedure room time with removal of trainee presence (staff endoscopist data only) for endoscopist-administered sedation and anaesthesiologist-administered sedation with propofol groups
EAC (n = 89)
AAP (n = 75)
P-value
Total procedure time
Mean ± SD
13.0 ± 4.9 min
12.9 ± 4.8 min
0.941
Total room time
Mean ± SD
28.1 ± 9.3 min
31.1 ± 10.1 min
0.019
Table 4 Results of the telephone patient satisfaction survey for endoscopist-administered sedation and anaesthesiologist-administered sedation with propofol groups n (%)
EAC (n = 104)
AAP (n = 126)
P-value
Response rate
74 (71)
80 (64)
0.219
Question 1: I was very satisfied with the care I received
0.074
Agree
15 (20)
8 (10)
Strongly agree
59 (80)
72 (90)
Question 2: I would strongly recommend this procedure to friends who qualify for it
0.882
Disagree
1 (1.4)
0 (0.0)
Not sure
2 (2.7)
6 (7.5)
Agree
16 (22)
13 (16)
Strongly agree
55 (74)
61 (76)
Question 3: I would be willing to repeat this examination again in the future if necessary
0.667
Disagree
0 (0.0)
1 (1.3)
Not sure
2 (2.7)
0 (0.0)
Agree
8 (11)
12 (15)
Strongly agree
64 (87)
67 (84)
Question 4: I did not experience too much pain/discomfort during the procedure
0.021
Strongly disagree
4 (5.4)
0 (0.0)
Disagree
5 (6.8)
2 (2.5)
Not sure
1 (1.4)
0 (0.0)
Agree
7 (9.5)
6 (7.5)
Strongly agree
57 (77)
72 (90)
Table 5 Study endpoints - comparing staff endoscopists only with cases involving resident participation
Resident involved (n = 66)
Staff endoscopist only (n = 164)
P-value
Total procedure time
< 0.001
Mean ± SD
26.0 ± 10.2
12.9 ± 4.8
< 0.001
Total room time
< 0.001
Mean ± SD
44.4 ± 13.7
29.5 ± 9.8
< 0.001
Citation: Thornley P, Al Beshir M, Gregor J, Antoniou A, Khanna N. Efficiency and patient experience with propofol vs conventional sedation: A prospective study. World J Gastrointest Endosc 2016; 8(4): 232-238