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Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastrointest Endosc. May 16, 2014; 6(5): 168-175
Published online May 16, 2014. doi: 10.4253/wjge.v6.i5.168
Table 1 Summary of larger and more recent studies using cyanoacrylate for the management of gastric variceal bleeding
Ref.Type of studyNo. of patients (follow-up)Active bleedingHaemostasis rateRebleeding rateComplications
Cheng et al[19]Case series613 (30 mo)23%95%8%5% “major”
Kang et al[15]Retrospective127 (18 mo)38%98%23%3 % “major”
Seewaldet al[20]Retrospective131 (26 mo)63%100%7%0%
Paik et al[14]Retrospective121 (12 mo)26%91%13% (at 4 wk)2% (major complications)
Kind et al[21]Case series174 (36 mo)100%97%13% “late rebleeding”8%
Ali-Al et al[18]Retrospective37 (14 mo)86%95%28%0 % “major”
Rajoriyaet al[17]Retrospective31 (35 mo)Not recorded100%16%0 % “major”
6% “minor”
Table 2 Summary of studies using thrombin for the management of gastric variceal bleeding
Ref.Type of thrombin usedNo. of patients (follow-up)HaemostasisRebleeding
Williams et al[26]Bovine11 (9 mo)100%27%
Przemioslo et al[29]Bovine52 (15 mo)94%18%
Ramesh et al[27]Bovine13 (25 mo)92%0%
McAvoy et al[28]Human37 (22 mo)Not recorded10.8%