Repeat endoscopic submucosal dissection for recurrent gastric cancers after endoscopic submucosal dissection

Table 1 Characteristics of 5 initial endoscopic submucosal dissection cases

Patient No.	Sex	Age, yr	Tumor location	Macroscopic type	Tumor size, mm	Specimen size, mm	Operation time, min	Histologicaltype	Resection margin category
1	Male	78	LB LC	I + IIa	23	40	69	Tub2	R0
2	Male	67	LB PW	IIc	8	37	70	Tub1	R0
3	Male	64	Ant PW	IIa + IIc	14	36	47	Tub1	R0
4	Male	76	Ang PW	IIc	65	70	442	Tub2	R1
5	Male	51	Ang LC	IIc	40	45	44	Tub2	R0
Median		67			23	40	69

Ang: Angulus; Ant: Antrum; LB: Lower body; LC: Lesser curvature; PW: Posterior wall; R0: Negative resection margin; R1: Microscopic tumor infiltration; Tub1: Well differentiated adenocarcinoma; Tub2: Moderately differentiated adenocarcinoma; I: Elevated lesion; IIa: Slightly elevated lesion; IIc: Slightly depressed lesion.

Table 2 Characteristics of re-endoscopic submucosal dissection in 5 cases

Patient No.	Time after initial ESD, mo	Macroscopic type	Tumor size, mm	Specimen size, mm	Operation time, min	Histological type	Resection margin category	Complication
1	44	IIa	22	47	210	Tub2	R0	None
2	9	IIc	8	45	82	Tub1	R0	None
3	14	IIc	11	32	43	Tub1	R0	None
4	12	IIc	27	59	353	Tub1	R0	None
5	4	IIc	42	77	202	Por	R0	None
Median	14		22	47	202

R0: Negative resection margin; Tub1: Well differentiated adenocarcinoma; Tub2: Moderately differentiated adenocarcinoma; Por: Poorly differentiated adenocarcinoma; IIa: Slightly elevated lesion; IIc: Slightly depressed lesion; ESD: Endoscopic submucosal dissection.

Table 3 Comparisons between re-endoscopic submucosal dissection and initial endoscopic submucosal dissection cases

	Re-ESD (n = 5)	Initial ESD (n = 606)	P value
Tumor size	22 mm	11 mm	0.09
Median (range)	(8-42 mm)	(1.5-65 mm)
Specimen size	47 mm	34 mm	0.02
Median (range)	(32-77 mm)	(13-92 mm)
Operation time	202 min	67 min	0.06
Median (range)	(43-353 min)	(10-510 min)

ESD: Endoscopic submucosal dissection.