Effectiveness of outpatient percutaneous endoscopic gastrostomy replacement using esophagogastroduodenoscopy and propofol sedation

Table 1 Demographic and baseline characteristics of 221 patients

Gender (male/female)	127/94
Age (yr) (mean ± SD)	81 ± 14
Indication for PEG
CVA/CNSD/tumor	136/77/8
Number of replacement
1	127 (57%)
2	58 (26%)
3 and more	36 (16%)
Time to replacement (d) (mean ± SD)	271 ± 53
Type of catheter used previously
Bumper-tube-type	106
Bumper-button-type	103
Balloon-tube-type	4
Balloon-button-type	8

Values are numbers of patients except for age and time to replacement.PEG: Percutaneous endoscopic gastrostomy; CVA: Cerebrovascular accident; CNSD: Central nervous system disorders.

Table 2 Outcomes and complications of this percutaneous endoscopic gastrostomy replacement method

Successful procedure	221 (100%)
Propofol dose (mg) (mean ± SD)(range)	34 ± 11 (20-60)
Mean procedure time (range)(min)	5.9 (3-8)
EGD findings newly recognized (%)
Reflux esophagitis	12 (5.4)
Gastric ulcer	5 (2.3)
Gastric neoplasm	2 (0.9)
Duodenal ulcer	1 (0.5)
Type of new catheters chosen
Bumper-tube-type	112
Bumper-button-type	109
Oxygen administered	8 (3.6%)
Mask ventilation required	0
Heart rate < 50 beats/min	0
Blood pressure < 70 mmHg	0
Discharge within 45 min after the procedure	221 (100%)
Complications within 72 h of the procedure
Aspiration pneumonia	0
Bleeding	0
Perforation	0
Peritonitis	0

Values are numbers of patients except for procedure time and propofol dose. EGD: Esophagogastroduodenoscopy.

Table 3 Comparison of blood concentrations of propofol between PEG replacement patients and middle aged subjects who underwent esophagogastroduodenoscopy

	PEG replacement(n = 20)	Middle age (n=20)	P value
Gender (M/F)	10/10	10/10
Age (yr)	78 ± 2	52 ± 6	< 0.0001
Body weight (kg)	54 ± 9	57 ± 6	0.41
Dose used (mg)	30	60
Sedation level (moderate)	20	20
Blood propofol concentrations (ng/mL)
30 min after injection	130 ± 36	125 ± 35	0.55
60 min	60 ± 22	55 ± 19	0.47
120 min	37 ± 11	29 ± 14	0.45

Values are mean ± SD except for gender and sedation level (numbers of patients). PEG: Percutaneous endoscopic gastrostomy.