Image-enhanced endoscopy for diagnosis of colorectal tumors in view of endoscopic treatment

Table 1 Reports about image-enhanced endoscopy without magnification for differentiation between neoplastic polyps and non-neoplastic polyps (%)

Ref.	System	No. of cases	Accuracy	Sensitivity	Specificity	PPV	NPV
Henry et al[27]	NBI	126	90.0	93.0	88.0	93.0	91.0
Su et al[29]	NBI	110	92.7	95.7	87.5	93.0	92.1
Tischendorf et al[26]	NBI	100	89.0	87.9	90.5	92.7	84.4
Rex[28]	NBI	451	89.0	92.0	87.0	88.0	91.0
Lonqcroft-Wheaton GR	FICE	232	88.0	-	-	-	-
Pohl et al[61]	FICE	321	84.4	93.2	61.2	88.0	76.4
Yoshida et al[22]	FICE	151	89.4	89.4	88.0	93.4	83.3
Sato et al[34]	AFI	358	91.9	92.7	92.9	-	-

NBI: Narrow-band imaging; FICE: Flexible spectral imaging color enhancement; PPV: Positive predictive value; NPV: Negative predictive value; AFI: Autofluorescence imaging.

Table 2 Reports about image-enhanced endoscopy with magnification for differentiation between neoplastic polyps and non-neoplastic polyps (%)

Ref.	System	No. of cases	Accuracy	Sensitivity	Specificity	PPV	NPV
Machida et al[12]	NBI	43	93.4	100.0	75.0	91.2	100.0
Sano et al[14]	NBI	150	95.3	96.4	92.3	97.3	90.0
Wada et al[35]	NBI	617	96.7	90.9	97.1	-	-
Tanaka et al[17]	NBI	289	98.9	100.0	98.9	-	-
Togashi et al[6]	FICE	107	87.0	93.0	70.0	90.0	76.0
dos Santos et al[20]	FICE	111	92.8	97.8	79.3	93.0	92.0

NBI: Narrow-band imaging; FICE: Flexible spectral imaging color enhancement; PPV: Positive predictive value; NPV: Negative predictive value.

Table 3 Reports about image-enhanced endoscopy with magnification for differentiation of massively submocosal invasive cancer (%)

Ref.	System	No. of cases	Accuracy	Sensitivity	Specificity	PPV	NPV
Fukuzawa et al[39]	NBI	112	92.9	81.4	100.0	100.0	90.0
Wada et al[35]	NBI	584	96.1	100.0	95.8	-	-
Tanaka et al[17]	NBI	97	94.1	63.8	100.0	-	-
Ikematsu et al[58]	NBI	130	87.7	84.8	88.7	71.8	94.5
Yoshida et al[22]	FICE	124	98.3	77.7	100.0	100.0	98.2

NBI: Narrow-band imaging; FICE: Flexible spectral imaging color enhancement; PPV: Positive predictive value; NPV: Negative predictive value.