Capsule endoscopy compared with conventional colonoscopy for detection of colorectal neoplasms

Table 1 Procedure protocols and cleansing levels

Authors	Eliakim 2006[8]	Schoofs 2006[9]	Sieg 2009[12]	Van Gossum 2009[11]	Eliakim 2009[10]	Spada 2010[13] (Standard/modifiedprocedure)
Device	PCC1	PCC1	PCC1	PCC1	PCC2	PCC1
Day 2	Low fibre diet	-	-	-	-	-
Day 1	7-8 pm	6-9 pm	1-6 pm	6-9 pm	evening	evening
	PEG 2 L	PEG 3 L	PEG 3 L	PEG 3 L	PEG 2 L	PEG 3 L
Day 0					morning	morning
6-7 am	PEG 1 L	PEG 1 L	PEG 0.5 L	PEG 1 L	PEG 2 L	PEG 1 L
8-9 am	Tegaserod 6 mg	Domperidone 20 mg	Domperidone 20 mg	Domperidone 20 mg		Domperidone 20 mg
	Capsule ingestion	Capsule ingestion	Capsule ingestion	Capsule ingestion	Capsule ingestion	Capsule ingestion
10:00 am	NaP 30 mL	NaP 45mL	NaP 22mL	NaP 45 mL		NaP 45 mL/0.5 L PEG
	+
12 am-1 pm	Tegaserod 6 mg		NaP 22 mL		1-2 h later NaP 45mL
02:00 pm	NaP 15 mL	NaP 30 mL		NaP 22 mL	2 h later NaP 22 mL	NaP 22 mL/0.5L PEG
04:30 pm	Bisacodyl supp 10 mg	Bisacodyl supp 10 mg	Bisacodyl supp 10 mg		Bisacodyl supp 10 mg	Bisacodyl supp 10 mg
Cleansing level Good and excellent (%)	84.4	88	72	72	78	35/53

PCC1: PillCam Colon 1 (Given Imaging Ltd, Yoqneam, Israel); PCC2: Second generation of PillCam Colon (Given Imaging Ltd, Yoqneam, Israel).

Table 2 Sensitivity and specificity of colon capsule endoscopy for polyps 6 mm or larger performed with PCC1 and PCC2

	Eliakim[8]	Schoofs[9]	Van Gossum[11]	Spada[13]	Pilz[14]	Gay[15]	Sacher-Huvelin[16]	Eliakim[10]
Year	2006	2006	2009	2010	2010	2010	2010	2009
Device	PCC1	PCC1	PCC1	PCC1	PCC1	PCC1	PCC1	PCC2
N	84	36	328	40	36	128	545	98
Sens (%)	63	76	64	63	50	88	39	89
Spec (%)	94	64	84	87	76	76	88	76

PCC1: PillCam Colon 1 (Given Imaging Ltd, Yoqneam, Israel); PCC2: Second generation of PillCam Colon; N: Patients with complete examination; Sens: Sensitivity; Spec: Specificity.