Role of digital chromoendoscopy in detecting minimal change esophageal reflux disease

Table 1 Comparison of the outcomes from various types of standard and digital chromoendoscopy for minimal change reflux disease diagnosis

	Endoscopy with magnification[21]	NBI with magnification[29]	NBI without magnification[30]	FICE without magnification[31]
Sensitivity	64	55	86.6	77.8
Specificity	85	87	83.3	83.3
NPV	70	NA	83.3	55.6
PPV	80	NA	86.1	93.3
Accuracy	74	NA	NA	79.2
Criteria for the diagnosis	Punctuate erythema	Increased IPCLs	Increased vascularity with absence of round pit patterns	Triangular lesions
Interobserver1 agreement	NA	Fair	Good	Poor
Intraobserver1 agreement	NA	Fair	NA	NA

NA: Not available;

¹Gold standards for GERD diagnosis were different in each study.