Short term results of endoscopic submucosal dissection in superficial esophageal squamous cell neoplasms

Table 1 Clinicopathologic characteristic of esophageal SCNs

		Number of lesions
Location	Ce/Ut/Mt/Lt/Ae	3/12/9/3/0
En block resection rate	100% (27/27)
Tumor-free lateral margin rate	88.9% (24/27)
Tumor-free basal margin rate	92.6% (25/27)
Tumor-free lateral/basal rate	96.3% (26/27)
Mean tumor size [mean (SD)], mm (range)	21 ± 13 mm (2-55)
Mean specimen size [mean (SD)], mm (range)	32 ± 12 mm (10-70)
Macroscopic type	IIa/IIb/IIc/IIc + IIb	2/5/19/3
Preoperative determining depth of invasion of SCNs	m1/m2/m3/sm1/sm2	7/15/2/2/1
Histologic depth	Dysplasia/m1/m2/m3/sm1/sm2	1/6/14/4/0/2
Vessel infiltration (+)		2
Procedure time [mean (SD)], min	88 ± 65 min
Local recurrence		0
Complication (perforation)		1
The mean hospital length of stay	9 d
Balloon dilation (+)		3

Ce: Cervical esophagus; Ut: Upper thoracic esophagus; Mt: Middle thoracic esophagus; Lt: Lower thoracic esophagus; Ae: Abdominal esophagus; IIa: Superficial elevated type; IIb: Flat type; IIc: Superficial shallow depressed type; m1: Intraepithelial carcinoma; m2: Microinvasive carcinoma (invasion through the basement membrane); m3: Intramucosal carcinoma (invasion to the muscularis mucosae); sm1: Superficial invasion (less than 200 μm below the muscularis mucosae) in the submucosa; sm2: Middle invasion (more than 200 μm below the muscularis mucosae) in the submucosa; SCNs: esophageal squamous cell neoplasms.

Table 2 Comparison of ESD under general anesthesia with that under intravenous anesthesia

	General anesthesia	Intravenous anesthesia	P value
Mean tumor size (mm)	26.9	15.1	P < 0.05
Procedure time (min)	98	75	NS
Complication (perforation)	0	1	NS
The mean hospital length of stay (day)	9.6	8.4	NS

NS: Not significant; ESD: endoscopic submucosal dissection.

Table 3 Comparison of ESD with flex knife and flash knife

	Flex knife	Flush knife	P
Mean tumor size (mm)	20	23	NS
Procedure time (min)	78	100	NS
Complication (perforation)	0	1	NS
En block resection rate (%)	100	100	NS