Gadour E, Hoff AC. Gastric fundoplication with endoscopic technique: A novel approach for gastroesophageal reflux disease treatment. World J Gastrointest Endosc 2024; 16(10): 557-565 [PMID: 39473542 DOI: 10.4253/wjge.v16.i10.557]
Corresponding Author of This Article
Eyad Gadour, CCST, Doctor, FACP, FRCP, FRCPE, MBBS, MRCP, MSc, Associate Professor, Consultant Physician-Scientist, Department of Gastroenterology and Hepatology, King Abdulaziz Hospital-National Guard, King Abdullah Military City, Al Mubarraz, Ahsa 31982, Saudi Arabia. eyadgadour@doctors.org.uk
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Prospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Oct 16, 2024; 16(10): 557-565 Published online Oct 16, 2024. doi: 10.4253/wjge.v16.i10.557
Table 1 Patient characteristics, n (%)
Characteristic
Value
Sex
Male
11 (61.1)
Female
7 (38.9)
Age, years (mean ± SD)
35.4 ± 5.4
Initial Hill grade
IIa
4 (22.2)
IIb
14 (77.8)
Adverse events
1 (5.6)
Valve reinforcement at 12 months postoperatively
1 (5.6)
Table 2 Comparison of quality of life and DeMeester scores at the time of the procedure and 6 and 12 months postoperatively
Score
At the time of the procedure
6 months
12 months
P value
GERD-related QOL (50)
39.9 ± 4.0
8.4 ± 4.7
8.7 ± 5.0
< 0.001
GERD-related QOL (30)
21.8 ± 2.2
2.9 ± 3.3
2.5 ± 2.7
< 0.001
DeMeester
27.0 ± 6.5
10.6 ± 2.5
9.6 ± 2.4
< 0.001
Table 3 Comparison of gastroesophageal reflux disease -related quality of life at the time of the procedure and 6 and 12 months postoperatively
Assessment, n
At the time of the procedure
6 months
12 months
P value
Satisfied
0
17
17
< 0.001
Neutral
2
1
1
Dissatisfied
16
0
0
Table 4 Treatment efficacy with gastric fundoplication with an endoscopic technique
Characteristic, n
At the time of the procedure
6 months
12 months
P value
GERD during endoscopy
13
3
1
< 0.001
Anti-GERD medications
18
3
1
< 0.001
Citation: Gadour E, Hoff AC. Gastric fundoplication with endoscopic technique: A novel approach for gastroesophageal reflux disease treatment. World J Gastrointest Endosc 2024; 16(10): 557-565