Primary prophylaxis of variceal bleeding in patients with cirrhosis: A comparison of different strategies

doi:10.4253/wjge.v13.i12.628

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Dec 16, 2021 (publication date) through Dec 1, 2025

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World Journal of Gastrointestinal Endoscopy

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1948-5190

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Endosc. Dec 16, 2021; 13(12): 628-637
Published online Dec 16, 2021. doi: 10.4253/wjge.v13.i12.628

Table 1 Strengths and weaknesses of the different strategies for primary prophylaxis of variceal bleeding in cirrhosis

	NSBBs	Carvedilol	EVL
Prevention of mortality	+	+?	+?
Prevention of bleeding	+	+	++
Prevention of other complications of cirrhosis	+	+	-
Reduction in HVPG	+	++	-
Adverse effects	--	--	-
Serious adverse effects	-	-	--

The plus sign (+) indicates strength. The minus sign (-) indicates weakness. The question mark (?) indicates uncertainty. NSBBs: Traditional non-selective beta-blockers; EVL: Endoscopic variceal ligation; HVPG: Hepatic venous pressure gradient.

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Citation: de Mattos ÂZ, Terra C, Farias AQ, Bittencourt PL, Alliance of Brazilian Centers for Cirrhosis Care–the ABC Group. Primary prophylaxis of variceal bleeding in patients with cirrhosis: A comparison of different strategies. World J Gastrointest Endosc 2021; 13(12): 628-637
URL: https://www.wjgnet.com/1948-5190/full/v13/i12/628.htm
DOI: https://dx.doi.org/10.4253/wjge.v13.i12.628