Long term oncological outcome of laparoscopic techniques in pancreatic cancer

Table 1 Core information on distal pancreatic resection in pancreatic cancer patients

Ref.	No. of patients reported	Study	Median survival (mo)
			Open	Laparoscopic
Van Hilst et al[16], 2017	680	Comparative, 34 centers (propensity score matching) retrospective	28	31
Mitchem et al[12], 2012	47	Non comparative, single center retrospective	26	NA
Sahakyan et al[17], 2017	207	Non comparative, two centers retrospective	NA	32
Shin et al[18], 2015	150	Comparative, single center (propensity score matching)	29	33
		retrospective
Grossman et al[40], 2016	78	Non comparative, single center retrospective	25	NA

NA: Not applicable.

Table 2 Core information on pancreaticoduodenectomy/Whipple-procedures in pancreatic cancer patients

Ref.	No. of patients reported	Study	Overall survival
			Open	Laparoscopic	P value
Croome et al[7], 2014	322 LPD 108 OPD214	Comparative, retrospective single center	Median 21.8 mo	Median 25.3 mo	0.22
Nussbaum et al[24], 2016	7967 LPD 1191 OPD 6776	Comparative Registry (NCDB) Retrospective	Two year 47%	Two year 43%	NS
Conrad et al[26], 2017	65 LPD 40 OPD 25	Comparative, retrospective two centers	Median 29.6 mo	Median 35.5 mo	NS

LPD: Laparoscopic pancreaticoduodenectomy; OPD: Open pancreaticoduodenectomy; NCDB: National Cancer Data Base; NS: Not significant.