Propofol vs midazolam sedation for elective endoscopy in patients with cirrhosis: A systematic review and meta-analysis of randomized controlled trials

Figure 1 Flow chart of study selection. Cochrane CENTRAL: Cochrane Central Register of Controlled Trials; Propofol vs midazolam sedation for elective endoscopy in patients with cirrhosis.

Figure 2 Overall risk of bias.

Figure 3 GRADEpro. Propofol vs midazolam sedation for elective endoscopy in patients with cirrhosis. A systematic review and meta-analysis of randomized controlled trials. ^aRiphaus A, 2009 risk of bias high. Khamaysi, 2011 and Weston BR. 2003 some concerns. ^bHigh heterogeneity. ^cNon significant difference. ^dRiphaus A 2009, Risk of bias high. Khamaysi, 2011 and Weston BR. 2003, risk bias some concerns. ^eKhamaysi, 2011 and Weston BR. 2003, Risk of bias some concerns. ^fRiphaus A, 2009 risk of bias high in (Bradycardia, Hypotension and Hypoxemia). CI: Confidence interval; MD: Mean difference.

Figure 4 Forest plot comparing procedure time between propofol and midazolam group for sedation during elective upper gastrointestinal endoscopy in patients with cirrhosis.

Figure 5 Forest plot comparing recovery time between propofol and midazolam group for sedation during elective upper gastrointestinal endoscopy in patients with cirrhosis.

Figure 6 Forest plot comparing discharge time between propofol and midazolam group for sedation during elective upper gastrointestinal endoscopy in patients with cirrhosis.

Figure 7 Forest plot comparing adverse events between propofol and midazolam group for sedation during elective upper gastrointestinal endoscopy in patients with cirrhosis.