Guo LH, Hu KF, Miao M, Ding Y, Zhang XJ, Ye GL. Endoscopic resection of colorectal laterally spreading tumors: Clinicopathologic characteristics and risk factors for treatment outcomes. World J Gastrointest Endosc 2025; 17(6): 106412 [PMID: 40547554 DOI: 10.4253/wjge.v17.i6.106412]
Reader's ID:
08628847
Submitted on:
June 20, 2025, 09:41
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Reader Comments:
This paper provides valuable insights into the clinicopathologic characteristics and treatment outcomes of colorectal laterally spreading tumors (LSTs) treated with endoscopic resection techniques. The study identifies key predictive factors such as tumor size, morphology, and histological grade, which are associated with high-grade dysplasia, carcinoma, and submucosal invasion. The development of a nomogram model that incorporates these factors is a significant contribution, offering a practical tool for predicting treatment outcomes. However, the study is retrospective, and its applicability to broader clinical settings could be improved with prospective, multi-center trials. Despite this, the paper’s detailed analysis of risk factors and its proposed nomogram for predicting clinical outcomes provide valuable guidance for clinical practice and future research in the field of colorectal cancer prevention and treatment.
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