Paramythiotis D, Tsavdaris D, Karlafti E. Reassessing cholecystectomy timing in gallstone-related acute cholangitis. World J Gastrointest Endosc 2025; 17(5): 106473 [PMID: 40438711 DOI: 10.4253/wjge.v17.i5.106473]
Reader's ID:
03669439
Submitted on:
May 15, 2025, 07:23
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Reader Comments:
This Letter to Editor does a great job of highlighting an important issue that many of us face in real-world clinical practice—when to perform cholecystectomy in patients with gallstone-related acute cholangitis.
The authors point out the growing evidence in favor of same-admission surgery rather than waiting, and they support this with data from a large national database, which adds weight to their argument.
What I appreciated most was how clearly the authors outlined the benefits of early surgery—not just in terms of clinical outcomes like reduced readmission and mortality, but also from a healthcare system perspective. These are the kinds of practical, patient-centered decisions we need to think more carefully about.
That said, I would have liked to see a little more discussion on what makes early surgery difficult to implement in some hospitals. For example, resource limitations, operating room availability, or patient comorbidities could be relevant factors. A few thoughts on how to overcome those barriers would make the piece even more helpful.
In summary, this is a well-written and very relevant commentary that reminds us of the gap that often exists between evidence and practice. I think it will be helpful not only for clinicians but also for institutions looking to improve care pathways for biliary emergencies.
Reviewer Name: Bum-Soo Kim
Reply from the Editorial Office:
First, thank you very much for your professional comments on the article published in World Journal of Gastrointestinal Endoscopy.
Second, we read your comments with great interest. You are welcome to format your valuable comments into a Letter to the Editor and submit it online to World Journal of Gastrointestinal Endoscopy at https://www.f6publishing.com. There are no restrictions on the number of words, figures (color, B/W) or authors for a Letter to the Editor. In addition, the article processing charge will be exempted for this Letter to the Editor. As with all articles published by the Baishideng Publishing Group, the Letter to the Editor will be published online after completing peer review. The guidelines for a Letter to the Editor can be found at: https://www.wjgnet.com/bpg/GerInfo/219.
Finally, we look forward to receiving your high-quality Letter to the Editor, which will promote academic communication and lead the development of this discipline.