miRNA在HBV从感染经由肝硬化到肝癌进程中表达谱的变化

表1 miRNA芯片和实时定量PCR检测差异表达miRNA的结果

	miRNA分子	芯片结果			实时定量PCR结果
		B/A	C/A	C/B	B/A	C/A	C/B
上调的miRNA	hsa-miR-602	3.234	4.134	1.278	2.703	3.486	1.290
	hsa-miR-129-5p	2.246	6.322	2.815	2.852	4.347	1.524
	has-miR-210	5.159	4.274	0.828	3.531	2.894	0.820
	hsa-miR-671-5p	4.315	4.249	0.985	2.953	3.624	1.227
	hsa-miR-30b*	3.571	4.005	1.122	3.841	4.896	1.275
	hsa-miR-572	3.588	3.092	0.862	4.319	4.291	0.994
下调的miRNA	hsa-miR-143	-3.661	-5.764	-1.575	-2.762	-3.521	-1.275
	hsa-miR-199a-5p	-3.288	-5.139	-1.563	-2.482	-2.730	-1.100
	has-miR-195	-3.066	-3.251	-1.060	-2.501	-2.943	-1.177
	hsa-miR-27a	-2.193	-3.147	-1.435	-3.492	-3.246	1.076
	hsa-miR-99a	-2.137	-2.746	-1.285	-3.581	-3.484	1.028
	hsa-miR-519e	-2.653	-2.674	-1.008	-2.898	-3.572	-1.233
	has-miR-130a	-2.016	-2.740	-1.225	-3.805	-3.872	-1.018
	hsa-miR-597	-2.071	-2.357	-1.138	-3.736	-4.058	-1.086