曹斌, 姚林华, 冯昕. 蒺藜皂苷通过调控Wnt3a/β-catenin信号通路抑制胃癌细胞增殖、迁移侵袭的机制研究. 世界华人消化杂志 2022; 30(4): 191-197 [DOI: 10.11569/wcjd.v30.i4.191]
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March 18, 2022, 07:20
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本研究通过探讨蒺藜皂苷对胃癌细胞增殖、迁移、侵袭的影响，同时又研究蒺藜皂苷对胃癌细胞增殖和转移相关的蛋白表达的影响；又通过蒺藜皂苷对胃癌细胞Wnt3a、β-catenin蛋白表达影响来研究对Wnt/β-catenin信号通路相关蛋白表达的影响。但最后通过干扰Wnt3a对Wnt/β-catenin信号通路相关蛋白表达的影响，并不足以说明蒺藜皂苷通过Wnt3a、β-catenin蛋白来调控Wnt/β-catenin信号通路，本文缺乏蒺藜皂苷+Wnt3a过表达组来说明是否通过Wnt3a、β-catenin蛋白来调控Wnt/β-catenin信号通路，此外，如果两株细胞更能具有说服力