余冠华, 姜争. 糖尿病与结直肠癌相关性的研究进展. 世界华人消化杂志 2021; 29(23): 1323-1333 [DOI: 10.11569/wcjd.v29.i23.1323]
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December 30, 2021, 08:49
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该文章对糖尿病与结直肠癌的相关性研究进行了分析。包括:流行病学研究、机制研究和降糖药对结直肠癌影响三方面。文章引用数据详实可靠,参考文献全面,归纳总结出新合理,逻辑性强。是一篇非常有实用性的综述。综述不仅提出了正面研究同时,对取得了反向结果的研究也进行了分析,对读者正确理解糖尿病与结直肠癌的相关性有了更全面的引导。文中从高血糖、高胰岛素、胰岛素样生长因子、慢性炎症预氧化应激等方面细致阐述了糖尿病与结直肠癌的关系,可理解性较强。同时,在文中我们也了解到了常用降糖类药物对结直肠癌的影响,对临床的应用与治疗也有很好的借鉴作用,是一篇兼顾实用与学术价值的优秀综述 。
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03770084
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December 21, 2021, 15:58
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本文从病理生理学角度概括糖尿病促进结直肠癌发生发展的机制,以及降糖药物对结直肠癌的影响,论证了糖尿病和结直肠癌存在的密切关系。本文内容全面,选题贴合临床实际,论据客观,对临床实践具有一定的指导意义。