锁瑞洋, 王芝馀, 王健生, 张广健, 张佳. 长链非编码RNA调控胃癌巨噬细胞极化研究进展. 世界华人消化杂志 2021; 29(19): 1096-1101 [DOI: 10.11569/wcjd.v29.i19.1096]
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October 20, 2021, 08:59
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肿瘤微环境对胃癌的异质性有一定作用, 而作为微环境中主要的成分, TAMs的研究有一定价值. 尽管目前已有诸多研究着眼于胃癌和lncRNAs信号通路的研究, 但对于lncRNAs调节胃癌巨噬细胞极化方面的研究不多, 少量的结果也并未很好的揭示相关通路的全貌。 筛选可作为肿瘤标志物的单个或者组合lncRNA外, 尤其是与M2型巨噬细胞极化相关的lncRNA, 为寻求治疗靶点有一定价值.