任建峰, 冯平, 张其胜, 靖大道. 幽门螺旋杆菌感染与结直肠腺瘤复发的相关性分析. 世界华人消化杂志 2021; 29(16): 952-959 [DOI: 10.11569/wcjd.v29.i16.952]
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03736570
Submitted on:
September 01, 2021, 09:57
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Reader Comments:
作者对于幽门螺旋杆菌感染与结直肠腺瘤复发的相关性进行了分析,得出结论“幽门螺旋杆菌(Helicobacter pylori, H. pylori)感染是CRA复发的危险因素, 根除H. pylori可以减少CRA的复发”,对于临床有一定的参考价值。
通读全文,个人认为在文章中部分地方再添加清晰的介绍可能会更恰当,比如在1.1 材料中介绍入组733例,实际上733例应该是最后得到肠镜随访的病例数,但是,文章中没有详细介绍在研究的2018-01/2020-12期间该医院行肠镜检查的实际(包括未得到随访+得到随访)的腺瘤总例数,也没有入组的流程图,如果研究期间实际腺瘤总例数与最后纳入研究的733例样本相差较大的话,则得出的结果对于临床参考价值就下降;其次,在幽门螺杆菌阳性组(391例)中经过标准的抗HP治疗后,未得到根除的有201例,经过经典的四联疗法(PPI+铋剂+2种抗生素)2周,根除率低于50%,的确是太低了,最后,讨论部分尽可能紧贴文章得出的结果展开,避免不必要的叙述,避免论著综述化,个人观点,仅供参考,谢谢。
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