Baishideng Publishing Group

Giz N, Epshtein J, Savin B, Meir K, Slae M. Presentation and endoscopic resection technique of neonatal esophageal choristoma: A case report. World J Gastrointest Oncol 2026; 18(3): 113851

"We sincerely thank the editorial board and reviewers of the World Journal of Gastrointestinal Oncology for their rigorous and ..." [Read more]

"We sincerely thank the editorial board and reviewers of the World Journal of Gastrointestinal Oncology for their rigorous and constructive feedback, which greatly enhanced the clarity and scientific quality of our work. We are particularly grateful to the editorial team for their efficient handling of our manuscript and for supporting the open-access dissemination of our research. Finally, we thank Baishideng Publishing Group for providing a platform that enables our findings on dual-parameter liquid biopsy for hepatocellular carcinoma to reach the global scientific community. " [Collapse]

Sherief DE, Shehata HH, Nosair N, Othman AAA, Sadaka E, Elgamal R. Dual-parameter liquid biopsy using plasma miR-21-5p and T cell LAIR-1 mean fluorescence intensity for hepatocellular carcinoma diagnosis in a high-risk Egyptian cohort. World J Gastrointest Oncol 2026; 18(3): 116567

"It was a nice work. Communication was excellent. We believe that the content of the article will contribute to readers and literature. ..." [Read more]

"It was a nice work. Communication was excellent. We believe that the content of the article will contribute to readers and literature. I believe that lesions originating from different organs have been evaluated with a holistic perspective and that the technical details will be very useful and instructive. Thank you for everything. Kind regards " [Collapse]

Buyuktalanci DO, Cakir E, Kucukzeybek BB, Altindag SD, Yilmaz AF, Kiper HD, Dilek ON. Analysis of histopathological and clinical prognostic factors in lymphomas involving the gastrointestinal system. World J Gastrointest Oncol 2026; 18(3): 115912

"Option 1 The authors sincerely thank the reviewers for their thorough, insightful, and highly professional comments. Their valuable ..." [Read more]

"Option 1 The authors sincerely thank the reviewers for their thorough, insightful, and highly professional comments. Their valuable suggestions greatly helped improve the quality of this manuscript. We also appreciate the editorial team for their careful and professional handling of the submission. Option 2 The authors would like to express their sincere gratitude to the reviewers for their careful, in-depth, and constructive evaluation of the manuscript. We also thank the editors for their meticulous and highly professional work throughout the review and publication process. Option 3 The authors are deeply grateful to the reviewers for their rigorous and thoughtful assessment. Their professional and constructive comments were invaluable in improving the manuscript. We also sincerely appreciate the editorial team for their detailed and efficient support. " [Collapse]

Zhou LJ, Hao XY, Wang C, Ren NN, Wang YG. Comprehensive modeling of the Correa cascade in precancerous lesions of gastric cancer: Leveraging animal, cellular, and organoid systems for translational insights. World J Gastrointest Oncol 2026; 18(3): 113757

"I am very satisfied with the entire publication process. The peer review was rigorous and constructive, which significantly improved ..." [Read more]

"I am very satisfied with the entire publication process. The peer review was rigorous and constructive, which significantly improved the quality of our manuscript. The editorial staff and production team were highly professional and efficient, ensuring a smooth and timely online publication. It has been a pleasure working with the World Journal of Gastrointestinal Oncology. " [Collapse]

Luan WY, Zhang SP, Xu KZ, Shang YH, Hu WJ, Sun H, Miao YD. Microbiota-driven immunometabolic regulation in colorectal cancer: Mechanisms and therapeutic opportunities. World J Gastrointest Oncol 2026; 18(3): 115722

"The journal boasts a highly standardized, rigorous and efficient publication process. The editorial team is professional, meticulous, ..." [Read more]

"The journal boasts a highly standardized, rigorous and efficient publication process. The editorial team is professional, meticulous, responsible and thoughtful, providing patient guidance and timely feedback throughout the entire submission, review and publication procedure. I am extremely satisfied with the whole experience and would highly recommend it to other researchers. " [Collapse]

Li BC, Wang BZ, Han L, Zhang ZW, Wang Y, Zhang YJ, Zhang JN. Goosecoid drives colorectal cancer progression by inducing epithelial-mesenchymal transition. World J Gastrointest Oncol 2026; 18(3): 115028

"We sincerely appreciate the valuable comments and suggestions of the editors and reviewers. They provided me with excellent suggestions ..." [Read more]

"We sincerely appreciate the valuable comments and suggestions of the editors and reviewers. They provided me with excellent suggestions for my article and improved its quality. The review speed is very fast. The manuscript submit system and peer review procedure is very efficient and professional. The opinions of the reviewers are professional, and the editorial work of the editor is responsible. It was a nice experience indeed. I am eagerly looking forward to the next submission. " [Collapse]

Ma FC, Zhang GL, Chen GQ, Ling JW, Li YF, Chi BT, Tang YL, Peng W, Chen G, Wei DM, Rong MH, Ge LY. MiR-27b-5p promotes gastric cancer progression by targeting CREBZF to regulate the STAT3 pathway. World J Gastrointest Oncol 2026; 18(3): 113781

"The peer review process was excellent. The peer review report was very beneficial to improve the quality of the manuscript. The ..." [Read more]

"The peer review process was excellent. The peer review report was very beneficial to improve the quality of the manuscript. The manuscript editing quality is good with improvement of tables and graphs. The period of publication is a bit longer. My suggestion is to reduce the period from submission to publication. " [Collapse]

Aggarwal A, Mustahsin M, Shishir P. Comparison of intubating laryngeal mask airway and video laryngoscope during emergency intubation in patients who are critically ill. World J Crit Care Med 2026; 15(1): 112345

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working ..." [Read more]

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working with BPG. The reviewing process needs work. It takes numerous months before reviewers are found. The system could be improved by slimlining the entire submission process. Other journals take 1-2 for complete publication. " [Collapse]

Zeppieri M, Drigo A, Capobianco M, Visalli F, Cappellani F, Musa M, Giglio R, Tognetto D, Khouyyi M, Gagliano C, D’Esposito F, Inferrera L. Beyond glycemia: The influence of systemic inflammation, lipids, and the gut-retina axis in diabetic retinopathy. World J Diabetes 2026; 17(3): 114603

"I would like to thank the editorial team, reviewers, and production staff for their support throughout the submission, revision, and ..." [Read more]

"I would like to thank the editorial team, reviewers, and production staff for their support throughout the submission, revision, and publication process. The collaboration between authors and the editorial office was smooth, and the guidance provided during editing and proofreading helped ensure a high-quality final publication. I look forward to following future developments in the journal and contributing again in the future. " [Collapse]

Gil-Millán P, Lupiañez A, Caparrós S, Ribas A, Martínez-Vaquera S, Ortiz-Zuñiga Á, Hernández C, Simó R, Simó-Servat O. Impact of visceral adiposity on glycemic variability in patients with insulin-treated type 2 diabetes undergoing hemodialysis. World J Diabetes 2026; 17(3): 115771

"I would like to express my sincere appreciation for the excellent editorial and publication process followed by your journal during ..." [Read more]

"I would like to express my sincere appreciation for the excellent editorial and publication process followed by your journal during the handling of my manuscript. The entire process—from submission to peer review and final publication—was conducted in a very professional, transparent, and efficient manner. The constructive comments provided by the reviewers were extremely valuable and helped improve the quality and clarity of the manuscript. I am also grateful to the editorial office for their timely communication, guidance, and support throughout each stage of the publication process. I truly appreciate the efforts of the editorial board, reviewers, and journal staff in maintaining high academic standards and ensuring a smooth publication experience for authors. Thank you once again for your dedication and professionalism. I look forward to submitting my future research work to your journal. With best regards, Dr. Dharmsheel Shrivastav " [Collapse]

Singh S, Sharma VK, Shrivastav D. Molecular insights into hyperglycemia-associated coronary heart disease: From glycemic variability and heart rate dynamics to long noncoding RNAs. World J Diabetes 2026; 17(3): 115033

"I'm very satisfied with the online submission system, the peer review reports are very helpful with my manuscript, the editing quality ..." [Read more]

"I'm very satisfied with the online submission system, the peer review reports are very helpful with my manuscript, the editing quality of the article is high, the publication process runs smoothly, the demands regarding academic rules and standards are rigorous, the time to publication is short. I'm very willing to publish my manuscript in the journal . " [Collapse]

Zhou T, Pan Y, Jiao CQ. Advances in diagnostic prediction of coronary artery lesions in Kawasaki disease. World J Clin Pediatr 2026; 15(1): 112079

"Overall, the submission and peer review process was clear and straightforward. The online submission system was easy to use, and the ..." [Read more]

"Overall, the submission and peer review process was clear and straightforward. The online submission system was easy to use, and the peer review comments were constructive and helped improve the quality of the manuscript. The editorial team communicated appropriately during the process. However, the publication process after acceptance took longer than expected. " [Collapse]

Mohammed H, Y Fadul K, Naqvi SGA, Kharma N, Alfian Yusof A, Ahmad S, Farooq M, Javid S, Mohamed A, Abdel-Rahman ME, Harris T. Use of radiograph scoring systems to assess pulmonary disease severity in patients with COVID-19 pneumonia. World J Crit Care Med 2026; 15(1): 113684

""The submission and peer-review process was smooth and transparent. The reviewers provided constructive comments that helped improve ..." [Read more]

""The submission and peer-review process was smooth and transparent. The reviewers provided constructive comments that helped improve the clarity and quality of the manuscript. Communication from the editorial office was timely and helpful. We appreciate the professional handling of our manuscript and had a very positive experience with the journal." " [Collapse]

Qureshi MA, Sood M, Thakur P, Sood I. Maternal and neonatal determinants of newborn sepsis: A case-control study in resource-limited settings. World J Clin Pediatr 2026; 15(1): 111423

"No other comment. I think this series of journals are done very well and have given me a lot of opportunities. I hope the process ..." [Read more]

"No other comment. I think this series of journals are done very well and have given me a lot of opportunities. I hope the process for uploading submissions or the review interface can be further optimized; otherwise, I think everything else is done very well.It can be more flexible in terms of language requirements. " [Collapse]

Cui L, Deng JC, Zhang N. Recombinant human thrombopoietin in pediatric allogeneic hematopoietic stem cell transplantation: Clinical insights and future directions. World J Stem Cells 2025; 17(10): 112434

"The submission and peer-review process was smooth and transparent. The reviewers provided constructive comments that helped improve ..." [Read more]

"The submission and peer-review process was smooth and transparent. The reviewers provided constructive comments that helped improve the clarity and quality of the manuscript. Communication from the editorial office was timely and helpful. We appreciate the professional handling of our manuscript and had a very positive experience with the journal. " [Collapse]

Phavichitr N, Tantibhaedhyangkul R, Dumrisilp T, Prachuapthunyachart S, Chanpreecha W, Ratanamongkol P, Chongsrisawat V. Clinical outcomes of two lactose-free formulas in the management of acute childhood diarrhea. World J Clin Pediatr 2026; 15(1): 114953

"Seamless process, submitting an article, which was reviewed in a timely manner with rigorous peer review. The editorial team were ..." [Read more]

"Seamless process, submitting an article, which was reviewed in a timely manner with rigorous peer review. The editorial team were professional and guided the process in a fast and clear manner. Peer reviewers reviewed the article in the pre-specified time with good insight and comments on the article. Publishing with BPG was a very streamlined process. " [Collapse]

Cilia BJ, Haridy J, Raj A, Hannah N. Hepatic hydrothorax as a manifestation of decompensated cirrhosis: An update on current management and future directions. World J Hepatol 2025; 17(10): 110412

"I am very satisfied with the work of the team at the journal. The journal’s workflow is well-structured and rigorous. The PDF ..." [Read more]

"I am very satisfied with the work of the team at the journal. The journal’s workflow is well-structured and rigorous. The PDF preparation stage may take slightly longer than some of the other steps; however, overall, I believe the process is of very high quality. I have no additional suggestions, as the team is already doing an excellent job. " [Collapse]

Kiatvitchukul T, Dokkham P, Jeephet K, Srisingh K. Understanding recurrent wheezing: A parent’s guide. World J Clin Pediatr 2026; 15(1): 113430

"The peer review process was fair and constructive, and the reviewers’ comments were helpful in improving the quality of the manuscript. ..." [Read more]

"The peer review process was fair and constructive, and the reviewers’ comments were helpful in improving the quality of the manuscript. The editorial and publication processes were handled professionally, and communication from the editorial office was clear and supportive. One minor point is that the submission format and workflow differ somewhat from those of many other journals, which may require some time for authors to become familiar with. Overall, however, the publication process was satisfactory. " [Collapse]

Aoki Y, Kawano Y, Ga R, Endo K, Ueda J, Shimizu T, Yoshida H. Vasopressin and fluid retention after liver resection: Comparison with the renin-angiotensin-aldosterone system by surgical extent and liver function. World J Gastroenterol 2026; 32(10): 115167

"The editorial process was efficient and well organized. The peer-review comments were constructive and helpful in improving the quality ..." [Read more]

"The editorial process was efficient and well organized. The peer-review comments were constructive and helpful in improving the quality and clarity of our manuscript. We appreciate the professional support and guidance from the editorial team throughout the review and publication process, which contributed to the successful completion and online publication of our article. " [Collapse]

Chen CY, Hsu YH. Complete resolution of massive chronic subdural hematoma with refined layered middle meningeal artery embolization: A case report. World J Clin Cases 2026; 14(7): 116694

20906 items Read more >>

Article Quality Tracking-Peer-Review

"This review article summarizes the current knowledge regarding the structure and role of the gut–brain axis, particularly in the ..." [Read more]

"This review article summarizes the current knowledge regarding the structure and role of the gut–brain axis, particularly in the context of acute brain injury. The major components include direct connections between the intestines and the brain through neurological and hormonal systems, as well as indirect communication mediated by intestinal flora and inflammatory cytokines. The structural participants include the autonomic nervous system, comprising both sympathetic and parasympathetic pathways, and the hypothalamic–pituitary–adrenal axis. Within these systems, a vicious cycle may easily develop. Brain inflammation can lead to systemic inflammatory spillover, which may induce increased intestinal permeability (“leaky gut”). This, in turn, can further exacerbate systemic inflammation and subsequently worsen brain inflammation. Potential therapeutic approaches discussed in the manuscript include vagus nerve stimulation, prebiotics and probiotics, fecal microbiota transplantation, and nutritional support. However, the content of the manuscript is largely redundant and does not present novel therapeutic concepts. In addition, the manuscript lacks detailed discussion of the underlying mechanisms and does not provide specific guidance for clinical practice. Overall, the manuscript remains largely descriptive and narrative rather than presenting a rigorous scientific analysis." [Collapse]

Zhao X, Zhang W, Zhang Y, Liu XA. Gastrointestinal dysfunction after brain injury: Mechanisms and the role of the brain-gut axis. World J Gastroenterol 2026; 32(10): 115731

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Ribeiro Junior MAF, Dib Possiedi R, Stefani Pacheco L, de Cesaro Schpchacki N, Nafeesa Hashim S, Monteiro Tavares Pereira B. Direct peritoneal resuscitation in sepsis and intra-abdominal infection: A scoping review. World J Clin Cases 2026; 14(7): 118719

"Traditional Chinese Medicine has demonstrated satisfactory preclinical and clinical efficacy in patients with IBD. The data from the ..." [Read more]

"Traditional Chinese Medicine has demonstrated satisfactory preclinical and clinical efficacy in patients with IBD. The data from the review under comment demonstrate that TCM primarily acts through a holistic approach, affecting multiple signaling pathways and other immunological mechanisms, including the composition of the gut microbiota, intestinal barrier integrity, autophagy, and gene expression. TCM treats IBD by synergistically modulating immunity, repairing the intestinal barrier, restoring the gut microbiota, and regulating inflammatory pathways and autophagy. In recent years, a large number of research papers, mainly by Chinese researchers, have sought to identify the therapeutic components of these treatments on the one hand and to investigate their mechanisms of action on the other. Moreover, clinical data and meta-analyses of randomized controlled trials support the effectiveness of PKI. Taken together, these actions will provide PKI with a scientific basis and foundation for its results. It is truly remarkable that both the large pharmaceutical industries and the health providers, as well as the officials of various countries, do not fund large multicenter studies that use PKI or the so-called Alternative Medicine in patients with IBD, at least as a complementary treatment to traditional Western medicine. I believe that the path towards this direction is inevitable in the coming years. Congratulations to the authors of the review." [Collapse]

Zeng SH, Jiang XY, Lin DR, Zhang WJ, Wu YQ, Xu L, Guo SJ. Mechanisms and therapeutic potential of traditional Chinese medicine for inflammatory bowel disease. World J Gastroenterol 2026; 32(10): 115821

"The vascular anatomy of the head and neck is highly complex and variable, and accurately characterizing the spatial relationships ..." [Read more]

"The vascular anatomy of the head and neck is highly complex and variable, and accurately characterizing the spatial relationships between vessels and adjacent bony structures is essential for identifying high-risk patients and guiding surgical planning. In a well-written letter to the editor, Jiang and Li commented on the study by Karangeli et al., a computed tomography angiography-based investigation of the spatial relationship between the hyoid bone and the carotid arteries. That study, which included 224 patients, revealed significant anatomical variability and concluded that carotid–hyoid contact is far more common than previously recognized. These findings carry important implications for radiologists and surgeons, as such contact may predispose patients to dynamic carotid compression, transient ischemic events, or intraoperative vascular injury. Jiang and Li discussed the clinical significance of carotid–hyoid anatomy, its surgical relevance, and age-related considerations. They acknowledged that the study by Karangeli et al. highlights the importance of translating detailed anatomical knowledge into preventive strategies that integrate imaging precision with vascular protection. Their review of the literature also summarized findings from other studies, noting that differences in suprahyoid muscular tension, cervical biomechanical loading, or hormonal influences may alter the course of the carotid arteries and contribute to previously unrecognized, sex-specific vascular risk profiles. Certain anatomical configurations—particularly types VIII and XI—may lead to transient compression, displacement, or repetitive impingement of the internal carotid artery during swallowing, neck rotation, flexion-extension, or physical exertion. Jiang and Li called for comparable longitudinal and multiethnic population-based studies on the hyoid bone and proposed future research directions. They emphasized that the carotid–hyoid relationship is far from an anatomical curiosity; rather, it represents a critical interface with direct implications for cerebrovascular health, surgical safety, and diagnostic accuracy. The authors further noted that radiologists should maintain a heightened awareness of this anatomical relationship in patients with cryptogenic stroke, recurrent focal neurological deficits, or unexplained cervical symptoms. Incorporating carotid–hyoid topographic evaluation into routine CTA reporting not only enhances diagnostic completeness but also facilitates timely risk identification and meaningful prevention, bridging the gap between structural anatomy and clinical protection. The parent study holds substantial clinical significance and relevance, offering valuable insights that can aid clinicians in addressing complex clinical challenges and improving patient outcomes. The article was well written and edited in terms of structure, language and references, and no errors were identified." [Collapse]

Jiang SY, Li R. When anatomy becomes pathology: Rethinking carotid-hyoid contact in cerebrovascular events. World J Radiol 2026; 18(2): 116873

"This study demonstrated that perioperative blood transfusions during gastric cancer surgery are associated with increased postoperative ..." [Read more]

"This study demonstrated that perioperative blood transfusions during gastric cancer surgery are associated with increased postoperative inflammation and stress responses, higher complication rates, and worse long-term outcomes. These results emphasize the importance of reducing unnecessary transfusions during surgery for gastric cancer patients. The immunomodulatory effects and enhanced inflammatory responses of transfusions may adversely affect the prognosis of cancer patients. The researchers concluded that avoiding unnecessary transfusions may facilitate postoperative recovery and improve long-term outcomes in gastric cancer patients. Going forward, it will be important to closely evaluate the need for blood transfusions and develop strategies to minimize transfusions, such as exploring alternative therapies and improving surgical techniques to reduce blood loss." [Collapse]

Maurya P, Gupta A, Gupta N. Influence of blood transfusion on outcomes in patients with gastric cancer. World J Gastroenterol 2026; 32(10): 115683

"We know that Traditional Chinese Medicine is a comprehensive medical system with a history of over 2,000 years, whose offerings focus ..." [Read more]

"We know that Traditional Chinese Medicine is a comprehensive medical system with a history of over 2,000 years, whose offerings focus on restoring balance and harmony between body, mind, and environment. Among its therapeutic methods, herbal medicine holds a leading position through the use of natural recipes based on herbs and minerals, aimed at enhancing self-healing processes. It is particularly effective in treating, among others, autoimmune and inflammatory conditions. Traditional Chinese Medicine is constantly gaining ground as a complementary therapy in the West. The World Health Organization has already officially recognized it by including it in the International Classification of Diseases, which facilitates its integration into national health systems. Currently, its adoption is usually proposed as a parallel to Western medicine rather than a replacement for it. In the study under review, the authors, using complex methods, identified the main bioactive components of Lianhe Xiaozhi ointment and the pathophysiological mechanisms underlying its effective alleviation of metabolic dysfunction-associated steatotic liver disease. In a global system of pharmaceutical treatment of ever-increasing cost, studies such as the one under review are necessary to determine, with adequate scientific methodology, the active ingredients and their precise mode of action in specific pathological conditions. I would like to congratulate the authors on their excellent work. " [Collapse]

Nie LJ, Wang GX, Yang XY, Sun J, Cao YT, Lou Y, Lu YF, Yu JY, Zhou XQ. Lianhe Xiaozhi ointment ameliorates metabolic dysfunction-associated steatotic liver disease via peroxisome proliferator-activated receptor alpha pathway activation. World J Gastroenterol 2026; 32(9): 114544

"Thank you for the opportunity to review the quality of the following editorial. Please see my comments below: 1 Ethics: Not applicable ..." [Read more]

"Thank you for the opportunity to review the quality of the following editorial. Please see my comments below: 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: The included figure adds to the readability of the manuscript 5 Biostatistics: Not applicable given manuscript type 6 References: Appropriate/up-to-date references 7 Language: Concise/well-written editorial 8 Caveats or drawbacks: None " [Collapse]

Huang HY, Tian L. Kill two birds with one stone: Reprogramming tumor microenvironment with growth differentiation factor 11. World J Gastroenterol 2026; 32(9): 115259

"Re: Khalid A, Obadele OG, Alabi TO, Nedjim SA, Abdulwahab-Ahmed A, Mungadi IA. Practical approach to the review of bladder diverticulum ..." [Read more]

"Re: Khalid A, Obadele OG, Alabi TO, Nedjim SA, Abdulwahab-Ahmed A, Mungadi IA. Practical approach to the review of bladder diverticulum and its management. World J Clin Urol 2026; 15(1): 114046 [DOI: 10.5410/wjcu.v15.i1.114046] The authors report on “Practical approach to the review of bladder diverticulum and its management” The article, which provides a combination of literature review and personal experience, included a detailed discussion of the definition, etiology, pathogenesis, clinical presentation, diagnosis and treatment of bladder diverticulum. The following comments can be of benefit for future considerations: 1.The causes and treatment of bladder diverticulum in children are different from those in adults. So, it would have been better to focus on either of them. 2. The authors stated that “For example, in boys with posterior urethral valves, these diverticula can serve as a pressure relief mechanism to protect the kidneys from damage and maintain bladder function”. In this context, is it possible to treat these diverticula conservatively without active surgical intervention? If the answer is yes, what are the indications. 3. It would have been better to include the pros and cons of the different surgical techniques, namely, extravesical, intravesical, or transdiverticular. Are they comparable? [1,2] 4. Among the active treatment options of bladder diverticulum is transurethral electrovaporization of the diverticular mucosa. It would have been better to include it among the endoscopic treatment procedures [3]. 5. Is there a difference in the outcome between staged treatment versus concomitant treatment of the cause and the resulting secondary diverticulum, for example in cases with BOO? [4] 6. In cases of female diverticulum, which are very close to the urethra, what are the recommended tips and tricks [5]. References [1]. Perri D, Roche JB, Petrut B, Bozzini G. Bladder diverticula management - conservative and surgical outcomes: a narrative review from EAU endourology. Curr Opin Urol. 2026 Jan 1;36(1):79-85. doi: 10.1097/MOU.0000000000001307. Epub 2025 Jun 12. PMID: 40548586. [2]. Giannarini G, Rossanese M, Macchione L, Mucciardi G, Crestani A, Ficarra V. Robot-assisted Bladder Diverticulectomy Using a Transperitoneal Extravesical Approach. Eur Urol Open Sci. 2022 Sep 8;44:162-168. doi: 10.1016/j.euros.2022.08.016. PMID: 36110902; PMCID: PMC9468349. [3]. Chandhoke RA, Ghoniem GM. Transurethral Electrovaporization of Bladder Diverticulum: An Alternative to Open or Laparoscopic Bladder Diverticulectomy. J Endourol Case Rep. 2015 Oct 1;1(1):11-3. doi: 10.1089/cren.2015.29002.cha. PMID: 27579375; PMCID: PMC4996560. [4]. Gazzah W, Ben Taher S, Masmoudi S, Hamza M, Naouar S, Salem B. Management of multiple giant bladder diverticula: a comprehensive approach - a case report. Ann Med Surg (Lond). 2024 May 15;86(7):4187-4190. doi: 10.1097/MS9.0000000000002162. PMID: 38989198; PMCID: PMC11230813. [5]. Liao C, He Z, Wang X, Guo P, Xiong W. Laparoscopic surgery for female posterior urethral bladder diverticulum with bladder outlet obstruction: A case report. Medicine (Baltimore). 2023 Sep 1;102(35):e34971. doi: 10.1097/MD.0000000000034971. PMID: 37657035; PMCID: PMC10476744. " [Collapse]

Khalid A, Obadele OG, Alabi TO, Nedjim SA, Abdulwahab-Ahmed A, Mungadi IA. Practical approach to the review of bladder diverticulum and its management. World J Clin Urol 2026; 15(1): 114046

"The paper is an interesting review, concise, comprehensive, complex and well structured. I think this paper is welcome and relevant ..." [Read more]

"The paper is an interesting review, concise, comprehensive, complex and well structured. I think this paper is welcome and relevant for medical daily practice even if the pathology debated is rare. Gastrointestinal bleeding is a frequent presentation in clinical practice, therefore is important to known all possible causes of bleeding including secondary to a GI melanoma. There are no grammatical or spelling errors throughtout the text. " [Collapse]

De Nardi P, Guida S, Damiano G, Rizzo N, Samanes Gajate AM, Riva ST, Paolino G, Colombo M, Tummineri R, Rongioletti F, Mercuri SR, Chiti A, Sileri P, Russo V. Primary melanoma of the gastrointestinal tract. World J Gastroenterol 2026; 32(8): 114571

"The dose of ursodeoxycholic acid that was prescribed to the study groups were not matched in this project. The uncontrolled PBC ..." [Read more]

"The dose of ursodeoxycholic acid that was prescribed to the study groups were not matched in this project. The uncontrolled PBC patients enface with hypercholesterolemia. This could make bias while diagnosing metabolic criteria for the definition of MASLD. At the same time, the study groups should be matched for the dose of statin consumption. Statins also influence the cholesterol level and should be adjusted as a confounding factor." [Collapse]

Koky T, Drazilova S, Komarova S, Macej M, Toporcerova D, Janicko M, Spakova I, Rabajdova M, Marekova M, Jarcuska P. Adipokine profiles reflect metabolic dysfunction but not fibrosis in patients with primary biliary cholangitis. World J Hepatol 2026; 18(2): 113685

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Bhati G, Mongardini FM, Bhati K, Singh P, Bansal R, Bansal A, Mahajan S, Docimo L, Caricato M, Capolupo GT, Carannante F. Ruptured primary intrahepatic ectopic pregnancy: A case report and review of literature. World J Clin Cases 2026; 14(6): 118135

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Aby Hadeer R, Ghattas S, Farhat H, Maalouf H, Bitar JE, Ayash D, Mohtar F, Elias B, Wakim R. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal mucocele tumors: Five case reports and review of literature. World J Clin Cases 2026; 14(6): 117655

"Duodenal ischemia in systemic lupus erythematosus (SLE) is a pathological condition of severe lupus enteritis, in which blood flow ..." [Read more]

"Duodenal ischemia in systemic lupus erythematosus (SLE) is a pathological condition of severe lupus enteritis, in which blood flow to the intestinal tract is impaired, mainly due to vasculitis and thrombosis. It begins with sudden abdominal pain, vomiting, and fever, and progresses to ulcers, perforation, and necrosis, so early diagnosis by CT and prompt immunosuppressive therapy, such as steroid pulse therapy, are essential. Surgical treatment: If perforation or necrosis is observed, emergency surgery to remove the affected area is required. The authors performed a duodenal anastomosis to avoid PD, and complications such as bile duct stricture were alleviated with a stent after surgery. This is a good paper." [Collapse]

Kim YK, Jung HI, Kim H, Bae SH. Ischemic duodenal injury due to systemic lupus erythematosus: A case report. World J Gastroenterol 2026; 32(8): 115654

"1) Ethics - meets requirements («The study was approved by the Ethics Committee of National Cancer Center/Cancer Hospital, Chinese ..." [Read more]

"1) Ethics - meets requirements («The study was approved by the Ethics Committee of National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College in accordance with the ethical standards outlined in the 1964 Helsinki Declaration») 2) Methods - revision required. Key concerns: - Subjective criteria for SSA administration The SSA-treated group includes zero patients with perineural invasion, but the endoscopy-alone group has 1 patient. Lymphovascular invasion was present in both groups (10.5% vs 9.6%), but no clear criteria for SSA initiation are provided. This distribution is clinically illogical and indicates selection bias. - Deviation from international guidelines (ENETS/NCCN) 73.4% of patients had tumors ≤ 10 mm without muscularis propria invasion. Current guidelines do not recommend adjuvant SSA therapy in this low-risk population. A substantial proportion of SSA-treated patients may have received overtreatment. Required revisions: Provide an objective, reproducible algorithm for SSA allocation. Perform a subgroup analysis of low-risk patients (≤10 mm, G1, no LVI/PNI). 3) Results - revision required. • The authors state: «However, endoscopic treatment removes lesions without addressing the underlying pathogenesis, allowing gastrin to continue stimulating neuroendocrine cell growth. Therefore, G-NETs may recur after endoscopic treatment». However, gastrin levels were not measured in this study. As a result: the suppressive effect of SSAs on gastrin was not documented and a direct correlation between gastrin reduction and improved outcomes could not be established. • Presented descriptively (n = 27, 6 mutations), with no integration into the main prognostic analysis. It is unclear how these data correlate with the risk of progression or response to therapy. This section appears redundant and detracts from the main clinical conclusions. 4) Figures and tables – good, minor issues Tables 1–4 and Figures 2–4 are clear, well-structured, and properly labeled. Figure 5: Descriptive genetic data only; not integrated into prognostic analysis. Limited relevance to main findings. Recommend moving to Supplementary Materials. 5) Biostatistics - adequate. LASSO and Cox regression correctly used, but no sample size calculation, wide CIs, and potential immortal time bias—acknowledge in limitations. 6) References - good Relevant, up-to-date, no over-citation. 7) Language – good Clear, concise, grammatically correct. 8) Caveats or drawbacks • Retrospective single-center design with inherent selection bias: SSA allocation was subjective and no reproducible algorithm provided. • Deviation from guidelines: 73.4% of patients had low-risk where adjuvant SSAs are not routinely recommended — potential overtreatment. • No gastrin data: The proposed mechanism (SSAs suppress gastrin) remains unverified; correlation between SSA use and reduced progression is statistical, not mechanistically proven. • Genetic data (Figure 5): Descriptive only, not integrated into prognostic analysis; limited relevance to main clinical conclusions. " [Collapse]

Yang ZL, Wang HK, Liu Y, Dou LZ, Zhang YM, Ng HI, He S, Chi YB, Wang GQ. Progression after endoscopic treatment for type I gastric neuroendocrine tumors: A single-center retrospective study. World J Gastroenterol 2026; 32(8): 114268

"Peroxiredoxin 1 (Prdx1) has recently been shown to effectively inhibit the growth of colon cancer in experimental carcinogenesis in ..." [Read more]

"Peroxiredoxin 1 (Prdx1) has recently been shown to effectively inhibit the growth of colon cancer in experimental carcinogenesis in mice. The anticancer activity of this substance is based on pyroptosis. Pyroptosis is a key component of cell death. It directly suppresses the tumor by promoting gasdermin D-induced cell lysis and by releasing inflammatory factors that affect the so-called “cell death-anti-tumor immunity”. Peroxiredoxin 1 warrants further investigation for the development of co-expression markers (Prdx1/GSDMD). Furthermore, as the authors note, the efficacy of combination therapies targeting rPrdx1 should be studied promptly to promote personalized treatment of colon cancer." [Collapse]

Chen ZK, Zhao JW, Meng WY, Wang YG. Peroxiredoxin 1 as a novel pyroptosis inducer in colorectal cancer: Insights and future directions. World J Gastroenterol 2026; 32(8): 116016

"As a systematic review, this paper comprehensively covers the core research content of tumor organoids and provides a systematic ..." [Read more]

"As a systematic review, this paper comprehensively covers the core research content of tumor organoids and provides a systematic collation of knowledge in the field. However, there is room for optimization in terms of data rigor, content depth, and clinical relevance. To enhance its academic value, it is advisable to supplement detailed information on literature screening, strengthen the connection between technical details and clinical applications, enrich the comprehensiveness of discussions on limitations, and optimize the timeliness of case data and references. Other comments: Figures and tables: I think the paper should have more figures, rather than only tabels." [Collapse]

Agrawal H, Tanwar H, Gupta N. Tumor organoids in translational cancer research: Models for personalized therapy. World J Transl Med 2026; 12(1): 113050

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Alvarez M, Luna M, Suarez E, Rincon O, Guzman I, Mancera P. Thyroid collision tumor and Graves’ disease: A case report and review of literature. World J Clin Cases 2026; 14(5): 117016

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Bouayad A. Human leukocyte antigen variants and clinical features of primary biliary cholangitis: Cumulative contributions. World J Clin Cases 2026; 14(5): 115814

" Importantly, the authors of this study identified that prolonged disease duration and anxiety are independent high-risk factors ..." [Read more]

" Importantly, the authors of this study identified that prolonged disease duration and anxiety are independent high-risk factors for refractory GERD. Anti-anxiety interventions, standardized exercise prescriptions, and lifestyle factors such as sleep and weight management should be explored as a multidimensional risk-targeted intervention. However, in the real world, we have to distinguish between true refractory GERD and refractory reflux-like symptoms. A systematic evaluation of the patients is essential, as up to 40% of patients with GERD report inadequate symptom control with PPIs, but only a minority have true refractory GERD. Therefore, we should evaluate multiple aspects of the patient's behavior (e.g., optimizing PPI therapy, ensuring correct timing, increasing to twice-daily dosing, or switching to a different PPI) before proceeding with exercise prescriptions and anti-anxiety interventions. Moreover, alternative pharmacologic options, including Histamine-2 receptor antagonists (administered at bedtime for nocturnal symptoms, though tachyphylaxis limits long-term efficacy), potassium-competitive acid blockers, alginates and antacids, prokinetic agents, neuromodulators, bile acid sequestrants, and lifestyle modifications, should be tried in these patients, indicating that individualized, multidisciplinary care is essential. " [Collapse]

Zuo XY, Chen QQ. Beyond monotherapy by acid suppression: Reshaping the management of refractory gastroesophageal reflux disease. World J Gastroenterol 2026; 32(7): 116425

"The paper is interesting and fits well with the body of work addressing nontraditional factors causing myocardial infarction. In ..." [Read more]

"The paper is interesting and fits well with the body of work addressing nontraditional factors causing myocardial infarction. In particular the discussion is well written. I don't know if I've missed it, but I haven't seen a correlation between myocardial infarction and ethnicity. In Europe ethnicity is an important factor, given that Asian populations have a higher incidence of myocardial infarction at young ages." [Collapse]

Patel T, Farhan M, Bhatt NK, Fatah HA, Peniel JJ, Kaulgud VV, Mathew T, Bapat AM, Harazeen WS, Alatta AN, Awosika A. Non-traditional risk factors for myocardial infarction in adults under forty: A systematic review of emerging trends. World J Cardiol 2026; 18(2): 116172

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