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1
Galazka A, Stawarz K, Bienkowska-Pluta K, Paszkowska M, Misiak-Galazka M. Closure techniques for esophageal reconstruction after total laryngectomy and their impact on fistula formation. World J Clin Oncol 2025; In press
2025-06-19 | Browse: 1 | Download: 0
2
Stasinos I, Voulgaris TA, Alexopoulos T, Karamanolis GP. Combining techniques and technologies increases adenoma detection rates in colonoscopy: More is more. World J Gastrointest Endosc 2025; In press
2025-06-19 | Browse: 1 | Download: 0
3
Singh H, Patel AA, Pandy P, Omar BJ, Prasad A, Singh V, Sharma P, Bairwa M, Sihag RK, Tiwari A, Rajput D, Kulshrestha M, Saini S, Kumar A, Sarkar B, Duggal V, Agarwal A, Kaeley N, Dhingra G, Mahala P, Yesodharan V, Chauhan H, Kumari D, Chaudhary S, Sharma AK, Yadav R, Panda PK. The burden of multi-drug-resistant organisms in a tertiary healthcare institute in North India: Implications for regional public health. World J Exp Med 2025; In press
2025-06-19 | Browse: 3 | Download: 0
4
Saini M, Manchanda S, Bhalla AS, Kandasamy D, l Kakkar A, Thakar A. Multiparametric magnetic resonance imaging in differentiating benign and malignant sinonasal masses: A prospective study and literature review. World J Methodol 2025; In press
2025-06-19 | Browse: 3 | Download: 0
5
Ye YL, Liu L. Engineering the future of nanomedicine: Strategic approaches to extracellular vesicle-based drug administration regimens. World J Stem Cells 2025; In press
2025-06-19 | Browse: 3 | Download: 0
6
Al-Battashy A, Al-Farsi N. When hematology meets ophthalmology: Cytomegalovirus retinitis in pediatric stem cell recipients. World J Stem Cells 2025; In press
2025-06-19 | Browse: 1 | Download: 0
7
Chen Y, Cai SL. Effect of early micro-breastfeeding on growth rate and postpartum depression in preterm infants with low-birth-weight. World J Psychiatry 2025; In press
2025-06-19 | Browse: 2 | Download: 0
8
Cai YX, Wang YJ, Liu J. Association between anxiety-depression status and psychological resilience in patients with Parkinson’s disease: A risk factor analysis. World J Psychiatry 2025; In press
2025-06-19 | Browse: 4 | Download: 0
9
Li QS, Xiao XH, Cai YY, Xiao XP, Hu PX, Li H. Ultrasound grading of first metatarsophalangeal joint synovial hypertrophy associated with vitamin D in type 2 diabetes mellitus. World J Diabetes 2025; In press
2025-06-19 | Browse: 2 | Download: 0
10
English K. Red yeast rice with monacolin K for the improvement of hyperlipidemia: A narrative review. World J Clin Cases 2025; In press
2025-06-19 | Browse: 2 | Download: 0
11
Mao JX, Gao R, Wang Y, Yan XB, Wang HH. Surgical treatment of colorectal cancer: A multidimensional review. World J Gastrointest Surg 2025; In press
2025-06-19 | Browse: 2 | Download: 0
12
Suárez M, Simón S, Martínez R, Crespo J. Acute pancreatitis secondary to small-cell lung cancer metastasis: A case report and review of literature. World J Clin Cases 2025; In press
2025-06-19 | Browse: 6 | Download: 0
13
Huang XR, Zhu DS, Yu YH. Surgical resection for simultaneous intraductal papillary mucinous neoplasm of the bile duct and pancreatic duct: A case report. World J Gastrointest Surg 2025; In press
2025-06-19 | Browse: 2 | Download: 0
14
Huang HY, Lan J, Zhuang W. Role of circulating tumor DNA methylation in gastric cancer initiation and progression: A comprehensive review. World J Gastrointest Oncol 2025; In press
2025-06-19 | Browse: 4 | Download: 0
15
Liu QJ, Zhang JC, Wang YF, Zou MH, Zhou WX, Lu Y, Feng XC, Liu H. Correlation of radiotherapy, targeted therapy, and immunotherapy with hepatocellular carcinoma recurrence. World J Gastrointest Oncol 2025; In press
2025-06-19 | Browse: 5 | Download: 0
16
Lin XJ, Tang JE, Sun B, Wang AL, Chen Y, Chen L, Xue YY, Li AJ, Liu CY. SAC3 domain containing 1 intervention in energy metabolism reprogramming assists in the progression of hepatocellular carcinoma. World J Gastrointest Oncol 2025; In press
2025-06-19 | Browse: 8 | Download: 0
17
Shi JJ, Dang SS. Correction to: Prohibitin 1 inhibits cell proliferation and induces apoptosis via the p53-mediated mitochondrial pathway in vitro. World J Gastrointest Oncol 2025; In press
2025-06-19 | Browse: 3 | Download: 0
18
Wu HY, Han L, Ran T, Sun Y, Zhang QX, Huang T, Zou GL, Zhang Y, Zhou YM, Lin GY, Chen SJ, Wang JL, Pan C, Lu F, Pu HF, Zhao XK. FBP1 as a key regulator of focal adhesion kinase-mediated hepatic stellate cell activation: Multi-omics and experimental validation. World J Gastroenterol 2025; In press
2025-06-19 | Browse: 3 | Download: 0
19
Negoi I. Correction to ”Personalized surveillance in colorectal cancer: Integrating circulating tumor DNA and artificial intelligence into post-treatment follow-up”. World J Gastroenterol 2025; In press
2025-06-19 | Browse: 3 | Download: 0
20
Akbulut S, Colak C. Edge learning applications in the prediction and classification of combined hepatocellular-cholangiocarcinoma: A comprehensive narrative review. World J Clin Oncol 2025; In press
2025-06-18 | Browse: 4 | Download: 0
627 items  Read more >>
Author Reviews
1
"I am satisfied with the review speed and publication cycle of this journal. The reviewers are serious and responsible, and the ..."  [Read more]
"I am satisfied with the review speed and publication cycle of this journal. The reviewers are serious and responsible, and the editorial department has a very professional attitude. I am willing to contribute to this journal again, and I am willing to recommend others to contribute. Thanks again to the editorial department and reviewers for their work. "  [Collapse]
Jin XY, Wang HZ, Yang K, Bao Y, Wang Y, Ben XL, Sun HY. Thoracic anterior controllable antedisplacement fusion for thoracic ossification of the posterior longitudinal ligament: A case report. World J Orthop 2025; 16(6): 107753
2
"The submission system of this journal is relatively user-friendly, featuring an intuitive interface and straightforward navigation ..."  [Read more]
"The submission system of this journal is relatively user-friendly, featuring an intuitive interface and straightforward navigation that simplifies the entire process. Smooth communication from the editors ensures a seamless experience, with prompt and professional responses to queries, fostering a collaborative atmosphere. The peer review process maintains high quality, characterized by meticulous scrutiny and constructive feedback, which significantly contributes to improving the academic standard of the articles, ensuring they meet rigorous scholarly benchmarks. "  [Collapse]
Gan D, Wang SY, Liu K, Zhang SY, Huang H, Xing JH, Qin CH, Wang KY, Wang T. Innovative exploration of phantom limb pain treatment based on extended reality technology. World J Orthop 2025; 16(6): 107422
3
"In this work,we evaluated that Gastritis cystica profunda (GCP) is a rare cystic proliferative lesion of the gastric glands.Due to ..."  [Read more]
"In this work,we evaluated that Gastritis cystica profunda (GCP) is a rare cystic proliferative lesion of the gastric glands.Due to the rarity of the condition and the limited number of reported cases, preoperative diagnosis is often unclear. Additionally, there is currently a lack of well-established treatment guidelines or protocols for managing GCP. In this paper, we present two cases of GCP: the first was misdiagnosed as a submucosal tumor, while the second was incorrectly diagnosed as a gastric polyp.The aim is to improve clinicians' cognitive level of the disease. "  [Collapse]
Zheng XL, Xu L, Wang J. Initial misdiagnosis of gastritis cystica profunda: Two case reports. World J Clin Cases 2025; 13(24): 107098
4
"We sincerely thank the reviewer and the editorial team for their professional and efficient handling of our manuscript. The reviewer ..."  [Read more]
"We sincerely thank the reviewer and the editorial team for their professional and efficient handling of our manuscript. The reviewer offered clear, constructive, and insightful comments that helped us significantly improve the quality of our work. We also appreciate the editor’s timely communication and guidance at each stage of the process. From submission to final publication, the experience has been smooth, respectful, and academically rigorous. We are grateful for the opportunity to publish in this journal and hope the article will be valuable to readers. "  [Collapse]
Zhou YJ, Wang BB, Wen HW, Xu L, Feng J, Xu FS. Clinical comparison of arthroscopic double-row rotator cuff repair with or without long head of biceps tendon transposition. World J Orthop 2025; 16(6): 103875
5
"This case underscores critical clinical lessons: First, unexplained skeletal pain with elevated ALP in the elderly warrants ..."  [Read more]
"This case underscores critical clinical lessons: First, unexplained skeletal pain with elevated ALP in the elderly warrants consideration of occult GI malignancies, even without primary tumor symptoms. Second, 68Ga-FAPI PET/CT proves indispensable when 18F-FDG fails to detect gastric cancers. Finally, patients with histories of premalignant lesions require vigilant endoscopic surveillance. We thank the editorial board and reviewers for recognizing this report’s role in mitigating diagnostic delays. Their expertise transformed our local experience into a globally accessible teaching tool. "  [Collapse]
Jin CB, Li YS, Zhang J, Wu J, Tao WJ. Extensive bone metastases from an occult gastric primary: A case report. World J Gastrointest Oncol 2025; 17(6): 106848
6
"We sincerely appreciate the rigorous peer review process and efficient editorial support throughout the publication process. The ..."  [Read more]
"We sincerely appreciate the rigorous peer review process and efficient editorial support throughout the publication process. The journal maintains strong credibility in gastrointestinal oncology research, evidenced by timely communication and transparent workflows. The reviewers provided insightful, constructive feedback that significantly strengthened our multicenter study. We look forward to contributing future work to the World Journal of Gastrointestinal Oncology (WJGO). "  [Collapse]
Li YH, Qian GX, Yao L, Lei XD, Zhu Y, Tang L, Xu ZL, Bu XY, Wei MT, Lu JL, Jia WD. Preoperative model for predicting early recurrence in hepatocellular carcinoma patients using radiomics and deep learning: A multicenter study. World J Gastrointest Oncol 2025; 17(6): 106608
7
"This article significantly contributes to an important area of knowledge by demonstrating the need for further studies to establish ..."  [Read more]
"This article significantly contributes to an important area of knowledge by demonstrating the need for further studies to establish the resolution and recurrence rates of endoscopic treatment using multiple plastic stents and covered self-expandable metal stents in patients with post-orthotopic liver transplantation biliary anastomotic stricture. This is of high clinical interest. "  [Collapse]
Pinheiro LW, Martins FP, Ferrari AP, Tafner E, De Paulo GA, Della Libera E. Long-term outcomes of post-transplant biliary anastomotic strictures: Endoscopic therapy with plastic and metal stents. World J Gastrointest Endosc 2025; 17(6): 103183
8
"The reviewers' comments were highly constructive, specific, and directly relevant to the subject matter. Their detailed feedback ..."  [Read more]
"The reviewers' comments were highly constructive, specific, and directly relevant to the subject matter. Their detailed feedback significantly improved the overall quality of the manuscript. It is evident that the journal selected expert peer reviewers who possessed strong subject knowledge and experience, which contributed to a focused and efficient review process. "  [Collapse]
Abuharb AIA, Alzamil AF, Alqarni KS, Alsudays AM, Alqahtani SM, Alahmadi RM, Mutairy ASA, Alghamdi FR. Merkel cell carcinoma presenting as a nasal dorsum mass: A case report and literature review. World J Clin Cases 2025; 13(24): 105244
9
"The authors sincerely appreciate the editorial and scientific efforts undertaken by Baishideng Publishing Group (BPG). We are highly ..."  [Read more]
"The authors sincerely appreciate the editorial and scientific efforts undertaken by Baishideng Publishing Group (BPG). We are highly satisfied with the efficiency, professionalism, and clarity demonstrated throughout the editorial process. The support and timely communication provided by the editorial team greatly contributed to the smooth and successful publication of our work "  [Collapse]
Savvidis C, Ilias I. Endocrine dysfunction in homozygous beta-thalassemia: An underrecognized and undertreated consequence of prolonged survival. World J Clin Cases 2025; 13(24): 107612
10
"We are very satisfied with the entire process of manuscript handling, including the online submission system, peer review, editing, ..."  [Read more]
"We are very satisfied with the entire process of manuscript handling, including the online submission system, peer review, editing, and final publication. The platform was easy to use, and the editorial staff communicated clearly and efficiently. The peer review reports were professional and helpful, contributing significantly to the improvement of our manuscript. The quality of the published article, including the layout of the figures and tables, was excellent. We appreciate the journal’s high standards and professional service throughout the publication process. "  [Collapse]
Wang YB, Li ZP, Wang P, Wang RB, Ruan YH, Shi Z, Li HY, Sun JK, Mi Y, Li CJ, Zheng PY, Zhang CJ. Iron dysregulation, ferroptosis, and oxidative stress in diabetic osteoporosis: Mechanisms, bone metabolism disruption, and therapeutic strategies. World J Diabetes 2025; 16(6): 106720
11
"I would like to provide some comments on the table formatting. Increase the width of Column 4 in Table 3, and decrease the width of ..."  [Read more]
"I would like to provide some comments on the table formatting. Increase the width of Column 4 in Table 3, and decrease the width of Columns 5 and 6, to optimize the visualization of the interquartile range (IQR) on a single row. Increase the width of Column 4 in Table 4, and decrease the width of Columns 2, to optimize the visualization of the P value on a single row. "  [Collapse]
Zaikova EK, Kaplina AV, Petrova NA, Pervunina TM, Golovkin AS, Kostareva AA, Kalinina OV. MicroRNA-320а as a novel biomarker at preclinical stage of necrotizing enterocolitis in term neonates with congenital heart defects. World J Clin Pediatr 2025; 14(3): 103652
12
"Thank you very much for your continuous support and understand of what the authors needs during their journey of publication. Really, ..."  [Read more]
"Thank you very much for your continuous support and understand of what the authors needs during their journey of publication. Really, we appreciate the support of both the reviewers with their constrictive criticism, and the editors for their editing procedures and efforts. I hope we continue the same sprite during the coming articles. "  [Collapse]
Al-Beltagi M, Saeed NK, Bediwy AS, Bediwy HA, Elbeltagi R. Cow milk protein allergy mimics in infancy. World J Clin Pediatr 2025; 14(3): 103788
13
"Thank you very much for your continuous support and understand of what the authors needs during their journey of publication. Really, ..."  [Read more]
"Thank you very much for your continuous support and understand of what the authors needs during their journey of publication. Really, we appreciate the support of both the reviewers with their constrictive criticism, and the editors for their editing procedures and efforts. I hope we continue the same sprite during the coming articles. "  [Collapse]
Al-Beltagi M, Saeed NK, Bediwy AS, Bediwy EA, Elbeltagi R. Unraveling functional neurological disorder in pediatric populations: A systematic review of diagnosis, treatment, and outcomes. World J Clin Pediatr 2025; 14(3): 105290
14
"Thank you very much for your continuous support and understand of what the authors needs during their journey of publication. Really, ..."  [Read more]
"Thank you very much for your continuous support and understand of what the authors needs during their journey of publication. Really, we appreciate the support of both the reviewers with their constrictive criticism, and the editors for their editing procedures and efforts. I hope we continue the same sprite during the coming articles. "  [Collapse]
Al-Beltagi M, Al Zahrani AA, Mani BS, Hantash EM, Saeed NK, Bediwy AS, Elbeltagi R. Challenges and solutions in managing dental problems in children with autism. World J Clin Pediatr 2025; 14(3): 106778
15
"We sincerely thank the World Journal of Clinical Pediatrics for the opportunity to share our work through the publication of this ..."  [Read more]
"We sincerely thank the World Journal of Clinical Pediatrics for the opportunity to share our work through the publication of this case report. The editorial process was professional, efficient, and highly supportive, with constructive feedback that greatly enriched our manuscripts. We appreciate the journal's commitment to advancing paediatric knowledge and providing a platform for clinicians and researchers from around the world. As early-career authors, this experience has been both affirming and inspiring. We are truly grateful for the guidance, timely communication, and editorial excellence that made this publication journey smooth and rewarding. We look forward to future submissions. "  [Collapse]
Omullo FP, Shahabi K, Kitheghe TK, Mutuku B, Simiyu BW. Phocomelia: Bilateral limb deficiency in a neonate: A case report. World J Clin Pediatr 2025; 14(3): 106524
16
"We sincerely thank the World Journal of Clinical Pediatrics for the opportunity to share our work through the publication of this ..."  [Read more]
"We sincerely thank the World Journal of Clinical Pediatrics for the opportunity to share our work through the publication of this case report. The editorial process was professional, efficient, and highly supportive, with constructive feedback that greatly enriched our manuscripts. We appreciate the journal's commitment to advancing paediatric knowledge and providing a platform for clinicians and researchers from around the world. As early-career authors, this experience has been both affirming and inspiring. We are truly grateful for the guidance, timely communication, and editorial excellence that made this publication journey smooth and rewarding. We look forward to future submissions. "  [Collapse]
Omullo FP, Mutisya N, Kinas E, Kitheghe T, Hassan Z, Muhonja R. Organophosphate poisoning presenting with paralytic ileus: A case report. World J Clin Pediatr 2025; 14(3): 106463
17
"Thank you very much for accepting the publication of our paper. We appreciate the suggestions from the editors and peer reviewers. ..."  [Read more]
"Thank you very much for accepting the publication of our paper. We appreciate the suggestions from the editors and peer reviewers. We are very satisfied with the peer review and publishing process. The journal has a simple, open, and transparent process for publishing papers. Overall, it was a good submission experience. "  [Collapse]
Li DH, Qiao C, Han YT, Ge JL. Kinesin family member 14 in digestive tract malignancies: Oncogenic mechanisms, clinical implications, and therapeutic prospects. World J Gastrointest Oncol 2025; 17(6): 105062
18
"I'm genuinely impressed with this journal's peer - review process. The time allocated for the review was just right, allowing for ..."  [Read more]
"I'm genuinely impressed with this journal's peer - review process. The time allocated for the review was just right, allowing for a thorough assessment without unnecessary delays. The anonymous peer - review mechanism created a level playing field, ensuring that my work was judged solely on its merits. The review report was a goldmine of useful suggestions. It pointed out both strengths and weaknesses in my manuscript, offering clear guidance for improvement. Most importantly, I found the report to be extremely fair and objective. There was no sign of bias or favoritism, which gives me great confidence in the journal's editorial standards and the integrity of its reviewers. "  [Collapse]
Ding J, Shi DD, Tian J. Chronic renal insufficiency and Nocardia brasiliensis infection: A call for heightened vigilance and multidisciplinary management. World J Clin Cases 2025; 13(24): 108115
19
"Every point of a peer review evaluation has been check marked. I am really satisfied with the way they helped me improve my manuscript ..."  [Read more]
"Every point of a peer review evaluation has been check marked. I am really satisfied with the way they helped me improve my manuscript and highlighted the results. The editorial board is really effective and communicative. The period of publication was good. I am really satisfied with the editing quality of the article. "  [Collapse]
Courbette O, Girard-Bock C, Cloutier A, Luu TM, Nuyt AM, Faure C. Prematurity is a risk factor of disorders of gut-brain interaction in adults: A case-control study. World J Clin Pediatr 2025; 14(3): 103590
20
"The process of writing and publishing the article was very standardized and orderly. The rules were very strict. The editorial ..."  [Read more]
"The process of writing and publishing the article was very standardized and orderly. The rules were very strict. The editorial department handled the problems very promptly. The submission process went very smoothly. This was a very satisfactory cooperation. I learned a lot. I'm very grateful for accepting my article and look forward to cooperating again. "  [Collapse]
Quan MJ, Lin Q. Prognostic value of post-neoadjuvant immunochemotherapy hypercoagulation in gastric cancer patients undergoing surgery. World J Gastrointest Oncol 2025; 17(6): 105085
18874 items  Read more >>
Article Quality Tracking-Peer-Review
1
" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..."  [Read more]
" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."  [Collapse]
Younus A, Liu Y, Connor EE, Wu ZY, Lee H, Fu ZY. Segmental atrophy of the liver: Review of a rare pseudotumor. World J Clin Cases 2025; 13(24): 107825
2
"The ethical approval meets requirements. The study obtained approval (CE24431B) from Taichung Veterans General Hospital. The methods ..."  [Read more]
"The ethical approval meets requirements. The study obtained approval (CE24431B) from Taichung Veterans General Hospital. The methods are effective and can be repeated by fellow researchers. They conducted a robust retrospective cohort using the TriNetX database, which harmonizes EHR data across 80 U.S. healthcare organizations. Besides, the inclusion and exclusion criteria are clear. The results of this study are authentic, reliable and validate the initial hypothesis. The tables, graphs, and figures were constructed and annotated well. But one mistake was presented in Table 3. Gestational hypertension HR typo ("HR: 1.936(1.844,0.033)" – "0.033" likely should be "2.033"). The biostatistics data was generally right. However, more details of PSM and some sensitivity analyses (e.g., competing risks for mortality) are suggested to be added. Authors have cited key references to support the pathophysiological mechanisms and prior epidemiological relationship, as well as some recent references. I suggest adding recent reviews on PIH-related metabolic dysfunction. The language is generally clear, concise, and logically structed."  [Collapse]
Shih YH, Yang CY, Lung CC. Long-term risk of diabetes following hypertensive disorders of pregnancy: A retrospective cohort study. World J Diabetes 2025; 16(6): 105080
3
"This was prospective study investigating factors that could potentially influence mesalamine adherence in patients with ulcerative ..."  [Read more]
"This was prospective study investigating factors that could potentially influence mesalamine adherence in patients with ulcerative colitis (UC), highlighting the impact of shared-decision-making on treatment outcomes. Basically, the results of the study indicate that when patients are involved in choosing their medication formulation, particularly granules, their adherence significantly improves, leading to better disease activity control. While acknowledging some limitations, such as reliance on self-reported adherence and potential participant dropout, the findings emphasize the importance of patient-centered care and accommodating individual preferences in long-term UC management. Ultimately, the study suggests that integrating shared-decision-making into routine gastroenterology practice might enhance adherence and overall outcomes. Regarding specific aspects: The ethical approval process appears to meet standard requirements based on the information provided. The study was reviewed and approved by the Ethics Committee of the North Rhine Chamber of Physicians, and registered on ClinicalTrials.gov. All study participants provided signed informed consent before study enrollment. Patient data were entered into an online electronic database using the double data entry method. The experimental method is described with sufficient detail to assess its effectiveness and potential for reproducibility. Basically, this was a 12-month, prospective, multicenter, non-interventional cohort study conducted at 113 specialty gastroenterology practices in Germany. The study design allowed for the collection of real-world data without formal interventions, which is highlighted as a strength. Eligibility criteria were clearly defined, and the inclusion of patients initiating or re-initiating mesalamine treatment in routine practice across Germany enhances the real-world applicability of findings. Decisions about diagnostic procedures and treatment were made by the treating physician according to patients’ clinical needs and independently of the study, ensuring routine clinical practice was observed. Disease activity was assessed using the partial Mayo score, with scores ranging from 0 to 9. Patient knowledge of UC was assessed using a self-developed, patient-administered questionnaire with two parts: self-rating and nine yes/no questions grouped into poor, moderate, or good/very good categories. Adherence was assessed using a self-developed, patient-administered questionnaire with a visual analogue scale (VAS). The reliance on a self-developed, self-reported VAS for adherence is noted as a potential limitation as it tends to overestimate adherence, though it is considered a simple and realistic measurement often used in practice. Patient involvement in treatment decision-making was not directly measured but inferred as a "proxy": instances where patients received their preferred mesalamine formulation were considered cases of shared decision-making. This is explicitly stated as an oversimplification and a limitation of the study. The authors provide information on the biostatistical methods used and present numerical results. The description of biostatistical methods and reported results appears to be correctly conducted. The results are presented clearly, supporting the study's aims and partially validating its hypothesis. However, the authors acknowledge that if all lost-to-follow-up patients are assumed to have suboptimal adherence, the rates drop dramatically at Visit 3, aligning more with previous literature. This demonstrates authenticity in acknowledging potential biases. Patient knowledge of UC (self-estimated or objectively measured) showed no significant association with adherence. Patients reporting good adherence experienced significant improvements in disease activity over 12 months. Patients who received their preferred formulation experienced continuous improvement in pMayo scores over 12 months. The figures, tables, and the diagram are clear and provide important information. The references provided suggest a reasonable approach to literature review on the subject., presenting relevant sources. There is no direct evidence to suggest self-citation, omission, mis-citation, or over-citation. The language used in the article is generally clear, concise, and grammatically correct. The study explicitly details its limitations in the "Strengths and limitations of the study" section. "  [Collapse]
Kruis W, Jessen P, Morgenstern J, Reimers B, Müller-Grage N, Bokemeyer B. Shared decision-making improves adherence to mesalamine in ulcerative colitis: A prospective, multicenter, non-interventional cohort study in Germany. World J Gastroenterol 2025; 31(22): 101915
4
"Authors studied a clinically important yet underexplored aspect of young-onset type 2 diabetes mellitus (T2DM): the association between ..."  [Read more]
"Authors studied a clinically important yet underexplored aspect of young-onset type 2 diabetes mellitus (T2DM): the association between vitamin D (VitD) status and apolipoprotein A1 (apoA1); a major component of HDL cholesterol with established cardioprotective properties. The study is one of the first to evaluate the relationship between VitD and apoA1 specifically in young-onset T2DM, a population at heightened risk for early cardiovascular morbidity and mortality. Since apoA1 plays a critical role in reverse cholesterol transport and HDL function, its association with VitD status provides a potential mechanistic link between VitD deficiency and increased cardiovascular risk in young-onset T2DM patients. However, the thresholds for “severe” VitD deficiency and the proportion of individuals in each deficiency category could be more clearly reported for better clinical applicability."  [Collapse]
Hu Y, Shao LN, Zheng J, Zhang XM, Song YX, Xing YB. Vitamin D deficiency is associated with apolipoprotein A1 levels in patients with young-onset type 2 diabetes mellitus. World J Diabetes 2025; 16(6): 105558
5
"Li et al's work is a narrative review article focusing on the emerging role of ferroptosis in the pathogenesis of diabetic ..."  [Read more]
"Li et al's work is a narrative review article focusing on the emerging role of ferroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) and its potential as a therapeutic target. Ferroptosis inhibitors (e.g., ferrostatin-1, liproxstatin-1, and iron chelators) have demonstrated protection against lipid ROS accumulation and reduction of cardiac injury and fibrosis in preclinical models. Ferroptosis is a cutting-edge area of research with growing relevance in diabetic complications. The review links molecular pathways (GPX4, ACSL4, iron metabolism) to clinical manifestations of DCM. Highlights ferroptosis inhibition as a potentially novel and actionable intervention for a currently untreatable condition. Justifies the need for alternative treatments beyond glycemic control in DCM. These agents are being explored for iron overload cardiomyopathies and may be repurposed or tailored for DCM."  [Collapse]
Li GZ, Liu JY, Zhou H. Ferroptosis: A novel therapeutic target for diabetic cardiomyopathy. World J Diabetes 2025; 16(6): 104665
6
"Authors studied an important limitation in diabetes management: the inadequacy of HbA1c in fully capturing glycemic control, ..."  [Read more]
"Authors studied an important limitation in diabetes management: the inadequacy of HbA1c in fully capturing glycemic control, particularly in patients with type 1 diabetes (T1D). The authors introduce and validate the Glycemia Risk Index (GRI) as a more holistic tool by integrating data from continuous glucose monitoring (CGM). Study results indicated that GRI showed strong inverse correlation with time in range (TIR) (r = -0.90) and positive correlations with time below range (TBR), time above range, and glycemic variability (CV)—metrics that HbA1c poorly reflects. Each 1% increase in TBR or CV substantially raises the GRI, highlighting its sensitivity to dangerous glycemic patterns that HbA1c alone would miss. While the GRI is statistically elegant, its ease of use and interpretation by patients and non-specialist clinicians remain unexplored. User-friendliness is critical for widespread adoption."  [Collapse]
He BB, Liu ZZ, Xu RY, Fan L, Guo R, Deng C, Xie YT, Zhou ZG, Li X. Glycated hemoglobin is not enough: The role of glycemia risk index for glycemic control assessment in type 1 diabetes. World J Diabetes 2025; 16(6): 104024
7
"Authors studied an under-researched probiotic, Acetobacter pasteurianus, linking it with diabetes treatment via lipid metabolites, ..."  [Read more]
"Authors studied an under-researched probiotic, Acetobacter pasteurianus, linking it with diabetes treatment via lipid metabolites, which is both innovative and timely given the rising interest in functional microbiota-derived therapeutics. The findings lay the groundwork for developing next-generation functional probiotics or postbiotics focused on metabolic diseases, particularly type 2 diabetes. While CoQ9 and OA were identified as hypoglycemic agents in the work, their precise molecular mechanisms of action (e.g., insulin sensitization, beta-cell preservation, or anti-inflammatory effects) remain unexplored sufficiently. No adequate data on signaling pathways (e.g., AMPK, PI3K/Akt) is included, which would strengthen the findings. "  [Collapse]
Xu WY, Zhou WT, Luo JZ, Jiang YY, Zhang K, Zhang SY, Liu PS, Wei HY, Huang YQ. Lipid metabolism of Acetobacter pasteurianus and its main components with hypoglycemic effects. World J Diabetes 2025; 16(6): 103370
8
"None Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according ..."  [Read more]
"None Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria. Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria"  [Collapse]
Sun M, Yu J, Zhou JW, Ye M, Ye F, Ding M. Can ChatGPT and DeepSeek help cancer patients: A comparative study of artificial intelligence models in clinical decision support. Artif Intell Cancer 2025; 6(1): 106356
9
"Thanks for your interesting article. I think some points in this article should be considered. The paper provides MAILE primarily ..."  [Read more]
"Thanks for your interesting article. I think some points in this article should be considered. The paper provides MAILE primarily narrative and theoretical foundations, much of the corroborative evidence coming from studies on generic isometric or core stabilization exercises. Although the authors themselves point out that direct empirical proof of MAILE is limited, no randomized controlled trials are available to contrast it with other core stabilization protocols. It is difficult to determine whether MAILE has any real clinical advantage or if it is simply a re-packaging of what is currently done, thus, in the lack of such comparisons. Additionally, besides subjective outcome measures like pain scales and questionnaires, objective physiological indicators like electromyography, motion analysis, or ultrasound imaging are desperately required in order to confirm that MAILE actually activates the assumed musculature as hypothesized. Identification of predictors of successful response to MAILE is another area that would benefit from more light. While the correlations reported (e.g., aberrant movement patterns, postpartum status, or positive Trendelenburg sign) are logical, they appear more based on the overall rehabilitation literature rather than specifically proven for MAILE. "  [Collapse]
Syed Y, Hassan MA, Kalayil RM, Othman OA, Mekkodathil A, El-Menyar A. Promising technique for managing nonspecific chronic low back pain using multi angular isometric lumbar exercise. World J Orthop 2025; 16(5): 104425
10
"AI is usefull a lot in many fields. ARLD is common in many countries with cirrhosis complication. The article with new idea has ..."  [Read more]
"AI is usefull a lot in many fields. ARLD is common in many countries with cirrhosis complication. The article with new idea has shown that using AI in ARLD management is very effective. Hopefully in the future many hospitals and medical centers will use AI in ARLD management to demonstrate effectiveness. "  [Collapse]
Chen ML, Jiao Y, Fan YH, Liu YH. Artificial intelligence for early prediction of alcohol-related liver disease: Advances, challenges, and clinical applications. Artif Intell Gastroenterol 2025; 6(1): 107193
11
"The benefits of PRF in regulating innate immunity and encouraging wound healing have been covered in this editorial. PRF is a possible ..."  [Read more]
"The benefits of PRF in regulating innate immunity and encouraging wound healing have been covered in this editorial. PRF is a possible treatment strategy for improved wound healing. It is a useful tool in therapeutic settings because of its ability to effectively promote tissue regeneration and modify innate immunity. PRF has the potential to greatly enhance patient outcomes and lessen the burden related to wound care as long as research into its processes and uses is conducted. The authors supported their manuscript by one figure and one table."  [Collapse]
Mohammadi S. Innate immunity and wound repair: The platelet-rich fibrin advantage. World J Biol Chem 2025; 16(2): 107195
12
"In this manuscript, the authors provided a lengthy conclusion. They found that, while CQ and HCQ have shown promise in the treatment ..."  [Read more]
"In this manuscript, the authors provided a lengthy conclusion. They found that, while CQ and HCQ have shown promise in the treatment of autoimmune diseases, there are several concerns and disputes surrounding their use. Although these drugs can help cure autoimmune illnesses, their use must be carefully considered in light of the benefits and drawbacks. The authors also stated that more study is needed to fully understand the therapeutic potential of CQ and HCQ in autoimmune diseases, maximize its use in clinical practice, and develop safer and more efficient treatments. In addition, the authors showed two nice figures."  [Collapse]
Al-Hamadani M, Darweesh M, Mohammadi S, Al-Harrasi A. Chloroquine and hydroxychloroquine: Immunomodulatory effects in autoimmune diseases. World J Biol Chem 2025; 16(2): 107042
13
"In an effort to transform the treatment of Parkinson's disease and enhance patient outcomes, this review addressed preclinical ..."  [Read more]
"In an effort to transform the treatment of Parkinson's disease and enhance patient outcomes, this review addressed preclinical achievements, long-term safety issues, and ethical considerations while highlighting the importance of stem cell therapy in neuroregeneration. Figures 1 and 2 are strong highlights in this manuscript, since Figure 1 depicts the classification of stem cells. As a result, this publication provided fundamental information regarding different types of stem cells and their applications in therapy."  [Collapse]
Mokhtari YG, Varnava I, Kyrgiannis K, Ampatsidou V, Giakoumettis D. Stem cell therapy for Parkinson’s disease: A new hope for neural regeneration. World J Biol Chem 2025; 16(2): 106850
14
"In recent years, to enhance the diagnostic capability of colonoscopy in detecting polyps in the large intestine, tiny ones, various ..."  [Read more]
"In recent years, to enhance the diagnostic capability of colonoscopy in detecting polyps in the large intestine, tiny ones, various computer-aided detection (CADe) systems have been increasingly utilized to improve the diagnostic accuracy of colonoscopy. In the study in question, the authors investigated precisely this possibility of CADe by conducting a meta-analysis of five relevant studies involving 1,624 examinees. They found that the adenoma missing rate was significantly lower in the group that underwent CADe compared to the group that underwent routine colonoscopy for small neoplasms. Interestingly, although the overall adenoma detection rate was not different between the two groups, it was higher in the group that underwent CADe during the first examination, suggesting that CADe significantly reduces the adenoma missing rate and polyp missing rate while improving the adenoma detection rate during the initial passage of the endoscope, thus demonstrating its potential to enhance the performance of colonoscopy. In recent years, we have witnessed the explosive growth and integration of artificial intelligence (AI) into clinical practice. It has been increasingly incorporated into clinical practice as it improves the detection of small and advanced colonic adenomas. The existing data strongly support the clinical application of AI in colonoscopy, as it significantly improves the diagnostic accuracy of endoscopy while reducing the endoscopic workload. However, over the next few years, the impact of AI applications is expected to be determined with precision, not only in the field of endoscopy but also in other areas of medical science, concerning not only gastroenterologists but also the effectiveness of daily therapeutic interventions."  [Collapse]
Wang SY, Gao JC, Wu SD. Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A systematic review and meta-analysis. World J Gastroenterol 2025; 31(21): 105753
15
"The healthy volunteers and the case groups should also be checked for conditions that would alter gut microbime including bacterial ..."  [Read more]
"The healthy volunteers and the case groups should also be checked for conditions that would alter gut microbime including bacterial overgrowth syndrome. This is a large entity that consists of GI motility disorders, anatomical anomalies and so on. There are large body of evidence regarding the role of bacterial overgrowth syndrome in progression of chronic liver disease. The enterance of bacterial endotoxins through portal vein as a result of leaky gut is another important issue that should be addressed in the methodology."  [Collapse]
Ma C, Yang J, Fu XN, Luo JY, Liu P, Zeng XL, Li XY, Zhang SL, Zheng S. Microbial characteristics of gut microbiome dysbiosis in patients with chronic liver disease. World J Hepatol 2025; 17(5): 106124
16
"A well desined study in the field of biliary stricture management. Further researches are needed to identify if stent placemnet would ..."  [Read more]
"A well desined study in the field of biliary stricture management. Further researches are needed to identify if stent placemnet would have added value to biliary dilation alone. It seemes that percutaneous approach might be more feasible in proximal strictures than the distal ones. Moreover, in ishemia induced strictures, timely diagnosis and appropriate intervention might be a key preventive management."  [Collapse]
Trifonov S, Kovalenko Y, Gurmikov B, Varava A, Vodeiko V, Pakhtushkin E, Vishnevsky V, Zharikov Y. Reconstructive surgery and percutaneous balloon dilation for the treatment of benign biliary strictures: A retrospective study. World J Hepatol 2025; 17(5): 104646
17
"Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an effective and minimally invasive alternative treatment for gastric outlet ..."  [Read more]
"Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an effective and minimally invasive alternative treatment for gastric outlet obstruction. Compared with conventional treatments such as duodenal stent placement and surgical gastrojejunostomy, EUS-GE has comparable technical and clinical success rates, with the advantages of longer patency, fewer adverse events, and lower reintervention rates. This technique is applicable not only to malignant obstruction, but also to complex pathologies such as benign lesions and afferent loop syndrome, and is a promising treatment that allows early recovery and resumption of oral intake, which is crucial for oncological patients. This review explained this point."  [Collapse]
Karagyozov PI, Kavrakov D, Shumka N. Endoscopic ultrasound-guided gastroenterostomy: The new standard treatment of gastric outlet obstruction. Artif Intell Gastrointest Endosc 2025; 6(2): 106600
18
"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..."  [Read more]
"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."  [Collapse]
Zhong XY, Liang ZJ, Lan ML, Xu XG, Yuan L, Zeng JX. Acinar cystic transformation of the pancreas: A rare case report. World J Clin Cases 2025; 13(23): 107096
19
"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..."  [Read more]
"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."  [Collapse]
Maity R, Rathna RB, Dhali A, Fernandes N, Biswas J, Kapoor GS, Dhali GK. Ulcerated benign jejunal gastrointestinal stromal tumor causing gastrointestinal bleeding: A case report. World J Clin Cases 2025; 12(23): 106140
20
"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..."  [Read more]
"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied."  [Collapse]
Cicek E, Karatepe YK, Kantarcı TR, Sahin TT. Demanding sleeve gastrectomy procedure in a patient with severe intraabdominal adhesions: A case report and review of the literature. World J Clin Cases 2025; 12(23): 104807
15299 items  Read more >>
Peer-Reviewers and Manuscript Statistics
Editorial board members
2266
Peer-reviewers
31753
Manuscripts received today
0
Manuscript reviews today
0
Unhandled manuscripts today
146
Active peer-reviewers today
356
Reviewer acceptance today
2
Reviewer refusals today
1
Total accepted manuscripts
36510
Total rejected manuscripts
42045
Total peer-reviewers
4256168
Total submissions
34703
Baishideng Publishing Group (BPG) publishes 47 peer-reviewed, open-access journals covering a broad range of topics in clinical medicine, as well as several topics in biochemistry and molecular biology, relevant to human health today.
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All Journal Articles
1

Parchwani D, Singh R, Patel D. Biological and translational attributes of mitochondrial DNA copy number: Laboratory perspective to clinical relevance. World J Methodol 2025; 15(3): 102709

2025-09-20 | Browse: 3934 | Download: 562
2

Tawheed A, Ismail A, El-Tawansy A, Maurice K, Ali A, El-Fouly A, Madkour A. Third space endoscopy pulmonary complications and chylothorax post peroral endoscopic myotomy. World J Methodol 2025; 15(3): 102703

2025-09-20 | Browse: 3824 | Download: 564
3

Bajpai J, Saxena M, Pradhan A, Kant S. Sotatercept: A novel therapeutic approach for pulmonary arterial hypertension through transforming growth factor-β signaling modulation. World J Methodol 2025; 15(3): 102688

2025-09-20 | Browse: 4429 | Download: 533
4

Bale BI, Zeppieri M, Idogen OS, Okechukwu CI, Ojo OE, Femi DA, Lawal AA, Adedeji SJ, Manikavasagar P, Akingbola A, Aborode AT, Musa M. Seeing the unseen: The low treatment rate of eye emergency in Africa. World J Methodol 2025; 15(3): 102477

2025-09-20 | Browse: 4256 | Download: 574
5

Vo LT, Vu T, Pham TN, Trinh TH, Nguyen TT. Machine learning-based models for prediction of in-hospital mortality in patients with dengue shock syndrome. World J Methodol 2025; 15(3): 101837

2025-09-20 | Browse: 3953 | Download: 779
6

Chauhan R, Padiyar N, Kaurani P, Gupta A, Chauhan S. Comparative evaluation of retentive capacity of three different attachment systems for implant retained overdentures: An in vitro study. World J Methodol 2025; 15(3): 101057

2025-09-20 | Browse: 4206 | Download: 659
7

Shah P, Shah VM, Saravanan VR, Kumar K, Narendran S. Evaluation of macular and peripapillary structure and microvasculature with optical coherence tomography angiography in migraine in Indian population. World J Methodol 2025; 15(3): 100950

2025-09-20 | Browse: 3953 | Download: 778
8

Drăgoi AL, Nemeș RM. “Electronic Pediatrician”, a non-machine learning prototype artificial intelligence software for pediatric computer-assisted pathophysiologic diagnosis — general presentation. World J Methodol 2025; 15(3): 100903

2025-09-20 | Browse: 3910 | Download: 702
9

Drăgoi AL, Nemeș RM. The remarkable effects of the ionized medical water Asea® in 3 boys with Duchenne dystrophy: Three case reports. World J Methodol 2025; 15(3): 100840

2025-09-20 | Browse: 4639 | Download: 653
10

Fawaz P, El Sayegh P, Vande Vannet B. Artificial intelligence in revolutionizing orthodontic practice. World J Methodol 2025; 15(3): 100598

2025-09-20 | Browse: 6186 | Download: 662
11

Khokhar RK, Nashwan AJ. Gut virome and its emerging role in inflammatory bowel disease. World J Methodol 2025; 15(3): 100534

2025-09-20 | Browse: 2770 | Download: 514
12

English K. Echo contrast medium: How the use of contrast echocardiography (ultrasound contrast agents) can improve patient care. World J Methodol 2025; 15(3): 100490

2025-09-20 | Browse: 3486 | Download: 528
13

Tramontana A, Rulli M, Falegnami A, Bilotta F. Visual avatar to increase situational awareness in anaesthesia: Systematic review of recent evidence. World J Methodol 2025; 15(3): 100459

2025-09-20 | Browse: 3880 | Download: 557
14

Li XL, Megdadi M, Quadri HS. Interaction between gut virome and microbiota on inflammatory bowel disease. World J Methodol 2025; 15(3): 100332

2025-09-20 | Browse: 2826 | Download: 454
15

Raveendran AV. Clinical inertia in sexual medicine practice. World J Methodol 2025; 15(3): 99874

2025-09-20 | Browse: 3760 | Download: 494
16

Tarazi A, Aburrub A, Hijah M. Use of artificial intelligence in neurological disorders diagnosis: A scientometric study. World J Methodol 2025; 15(3): 99403

2025-09-20 | Browse: 4789 | Download: 602
17

Casu C, Inchingolo AM, Orrù G. Interleukin 10 supplement to reduce episodes of recurrent aphthous stomatitis. World J Methodol 2025; 15(3): 99176

2025-09-20 | Browse: 3446 | Download: 496
18

Singh K, Nashwan AJ. Innovative forecasting models for nurse demand in modern healthcare systems. World J Methodol 2025; 15(3): 99162

2025-09-20 | Browse: 3039 | Download: 464
19

Kodali R, Parasar K, Anand U, Singh BN, Kant K, Arora A, Karthikeyan V, Anwar S, Saha B, Wadaskar S. Evidence-based approach for intraabdominal drainage in pancreatic surgery: A systematic review and meta-analysis. World J Methodol 2025; 15(3): 99080

2025-09-20 | Browse: 4021 | Download: 636
20

Al-Beltagi M. Fishing reviewing: A threat to research integrity and credibility. World J Methodol 2025; 15(3): 98795

2025-09-20 | Browse: 3308 | Download: 546
58938 items  Read more >>
Featured Articles
1

Amematekpor LD, Amankwaa-Frempong D, Owusu E. Visual outcomes following pediatric cataract surgery at Komfo Anokye Teaching Hospital in Ghana. World J Ophthalmol 2025; 9(1): 105857

2025-06-18 | Browse: 1 | Download: 0
2

Basit A, Kiran T, Shaista F, Saifullah M, Basil AM. Exogenous lipoid pneumonia associated with nasal decongestants use: A narrative review of an under recognized clinical entity. World J Respirol 2025; 14(1): 109353

2025-06-17 | Browse: 7 | Download: 23
3

Courbette O, Girard-Bock C, Cloutier A, Luu TM, Nuyt AM, Faure C. Prematurity is a risk factor of disorders of gut-brain interaction in adults: A case-control study. World J Clin Pediatr 2025; 14(3): 103590

2025-06-16 | Browse: 14 | Download: 28
4

Karunanayake A, Rajindrajith S, Kumari MV, Devanarayana NM. Effects of body mass index on gastric motility: Comparing children with functional abdominal pain disorders and healthy controls. World J Clin Pediatr 2025; 14(3): 100306

2025-06-16 | Browse: 10 | Download: 40
5

Soni P, Agrawal A. Pediatric emergency care: Determinants and systematic barriers. World J Clin Pediatr 2025; 14(3): 108140

2025-06-16 | Browse: 10 | Download: 19
6

Ghosh U, Samanta A. Monogenic inflammatory bowel disease: An unfolding enigma. World J Clin Pediatr 2025; 14(3): 107165

2025-06-16 | Browse: 11 | Download: 21
7

Al-Beltagi M, Saeed NK, Bediwy AS, Bediwy HA, Elbeltagi R. Cow milk protein allergy mimics in infancy. World J Clin Pediatr 2025; 14(3): 103788

2025-06-16 | Browse: 13 | Download: 33
8

Au SCL. Importance of data collection and subgroup analyses in research methodology. World J Meta-Anal 2025; 13(2): 104382

2025-06-16 | Browse: 8 | Download: 25
9

Agrawal H, Goswami B, Gupta N, Singh N. Liquid biopsy in hepatobiliary and pancreatic cancers: A paradigm shift in early detection, prognostic stratification, and perioperative monitoring. World J Meta-Anal 2025; 13(2): 107997

2025-06-16 | Browse: 9 | Download: 12
10

Ponukumati SH, Mittal R, Tafuto BA. Impact of socioeconomic factors on pediatric atopic dermatitis population. World J Meta-Anal 2025; 13(2): 105511

2025-06-16 | Browse: 10 | Download: 30
11

Pal P, Mateen MA, Pooja K, Rajadurai N, Gupta R, Tandan M, Duvvuru NR. Intestinal ultrasound in Crohn’s disease: A systematic review of its role in diagnosis, monitoring, and treatment response. World J Meta-Anal 2025; 13(2): 104080

2025-06-16 | Browse: 10 | Download: 18
12

Donmez Guler D, Kemik Z, Ates Bulut E. Frailty models and social frailty. World J Meta-Anal 2025; 13(2): 107388

2025-06-16 | Browse: 11 | Download: 26
13

Ding J, Shi DD, Tian J. Chronic renal insufficiency and Nocardia brasiliensis infection: A call for heightened vigilance and multidisciplinary management. World J Clin Cases 2025; 13(24): 108115

2025-06-16 | Browse: 14 | Download: 42
14

Cai J, Qin H. Mechanism analysis of periostin in osteoclasts differentiation of dental follicle: Two case reports. World J Clin Cases 2025; 13(24): 107535

2025-06-16 | Browse: 13 | Download: 52
15

Spinelli F, Petrella F, Cara A, Cassina E, Libretti L, Pirondini E, De Simone M, Cioffi U, Tuoro A, Cioffi G, Raveglia F. Minimally invasive surgical approach for slipping rib syndrome: A case report. World J Clin Cases 2025; 13(24): 107384

2025-06-16 | Browse: 14 | Download: 37
16

Cass K, Leggett A, Gibson DG. Diagnostic dilemma of avoidant/restrictive food intake disorder after bariatric surgery: A case report and review of literature. World J Clin Cases 2025; 13(24): 106941

2025-06-16 | Browse: 13 | Download: 31
17

Abuharb AIA, Alzamil AF, Alqarni KS, Alsudays AM, Alqahtani SM, Alahmadi RM, Mutairy ASA, Alghamdi FR. Merkel cell carcinoma presenting as a nasal dorsum mass: A case report and literature review. World J Clin Cases 2025; 13(24): 105244

2025-06-16 | Browse: 14 | Download: 47
18

Wei JR, Ouyang YN, Tang MT, Yuan JZ, Wang PL, Jiang LH, Wu LC. Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer. World J Gastrointest Oncol 2025; 17(6): 105967

2025-06-13 | Browse: 45 | Download: 107
19

Xu W, Li W, Ru J. Endothelial Per-Arnt-Sim domain-containing protein 1 expression is correlated with poor prognosis and promotes invasion and metastasis in gastric cancer. World J Gastrointest Oncol 2025; 17(6): 105213

2025-06-13 | Browse: 38 | Download: 81
20

Alpsoy A, Yavuz A, Simsek K, Altunay B, Karaca M, Unal B, Bassorgun CI, Tatli AM, Elpek GO. Evaluation of tumor budding, desmoplastic reaction, and lymphocytic infiltration in predicting survival for pancreatic ductal adenocarcinoma. World J Gastrointest Oncol 2025; 17(6): 107021

2025-06-13 | Browse: 36 | Download: 87
9594 items  Read more >>
Keyword Search Published Articles Processes
1
Case report
2853
2
Case report
1651
3
Hepatocellular carcinoma
1426
4
Gastric cancer
1002
5
Colorectal cancer
981
6
Inflammatory bowel disease
714
7
COVID-19
703
8
Prognosis
670
9
Liver transplantation
616
10
Treatment
552
11
Ulcerative colitis
552
12
Helicobacter pylori
517
13
Diagnosis
517
14
Crohn’s disease
513
15
Endoscopy
479
16
Cirrhosis
476
17
Meta-analysis
454
18
Pancreatic cancer
440
19
Magnetic resonance imaging
440
20
Surgery
423
69681 items  Read more >>
Reader Comments
1
"This study evaluated the technical and clinical success of minor papilla cannulation, sphincterotomy, and subsequent procedures, which ..."  [Read more]
"This study evaluated the technical and clinical success of minor papilla cannulation, sphincterotomy, and subsequent procedures, which are highly difficult among ERCP techniques. Although relatively rare, these procedures are essential for certain patients, and the significance of this study lies in its analysis of clinical outcomes based on long-term data. If treatments using EUS or single-operator cholangioscopy are investigated in further studies, researchers will need to demonstrate superiority over the results of this study. "  [Collapse]
Ren X, Qu YP, Xia T, Tang XF. Technical success, clinical efficacy, and safety of endoscopic minor papilla interventions for symptomatic pancreatic diseases. World J Gastroenterol 2025; 31(20): 100192
2
"Cass K et al.'s report of the first documented case of avoidant/restrictive food intake disorder (ARFID) following Roux-en-Y gastric ..."  [Read more]
"Cass K et al.'s report of the first documented case of avoidant/restrictive food intake disorder (ARFID) following Roux-en-Y gastric bypass (RYGB) surgery highlights critical diagnostic gaps in post-bariatric eating pathology assessment. This instance illustrates how ARFID, marked by the avoidance of food due to fear of adverse outcomes such as nausea, can arise independently after surgery, differing from body-image-centered disorders like anorexia nervosa. The likely reason for previous underreporting is diagnostic overshadowing, where symptoms are mistakenly attributed to expected surgical side effects, and limitations in the DSM-5-TR, which excludes patients experiencing weight-loss-related body dysmorphia but not driven by fat phobia. The patient's significant weight loss of 52.3 kg in just six months highlights the role of extreme weight suppression in inducing physiological stress, such as metabolic adaptation and hepatitis, which may exacerbate aversion to food. Additionally, voluntary vomiting, often reported by post-bariatric patients as a means of relieving discomfort rather than controlling weight, remains a challenging diagnostic issue. The current DSM-5-TR inaccurately categorizes this behavior as anorexia nervosa (AN) or bulimia, indicating a need for revised criteria for ARFID. Furthermore, body image disturbance in this population frequently stems from loose skin or identity disruption, rather than a fear of weight gain, emphasizing the importance of distinguishing this condition from AN to prevent ineffective treatments. Prospective studies are necessary for future endeavors to ascertain the prevalence of ARFID, refine the DSM criteria to differentiate behavioral motivations (such as vomiting intent), and establish integrated multidisciplinary care models. Given the widespread increase in bariatric surgeries, it is urgent to develop surgery-specific diagnostic frameworks. Clinicians must screen for ARFID in post-bariatric patients who avoid food due to fear of aversive outcomes, regardless of any concurrent body image issues or intentional vomiting. "  [Collapse]
Cass K, Leggett A, Gibson DG. Diagnostic dilemma of avoidant/restrictive food intake disorder after bariatric surgery: A case report and review of literature. World J Clin Cases 2025; 13(24): 106941
3
"The authors present a timely and comprehensive overview of endoscopic strategies for INP. Particularly commendable is the emphasis ..."  [Read more]
"The authors present a timely and comprehensive overview of endoscopic strategies for INP. Particularly commendable is the emphasis on procedural standardization, multidisciplinary decision-making, and the evolving role of lumen-apposing metal stents. However, I would like to highlight one important clinical aspect that merits more attention: the influence of patient-specific immunonutritional status and comorbidities. Numerous studies, including work by Zerem et al., have shown that sarcopenia, hypoalbuminemia, and diabetes mellitus are significant predictors of poor clinical outcomes and secondary infections, even after technically successful drainage procedures. Acknowledging and integrating these patient-level risk factors into procedural decision-making could enhance the individualization of care and improve long-term outcomes. Additionally, while the authors discuss timing and technique in detail, post-procedural follow-up protocols are only briefly addressed. Standardized imaging and biomarker-based follow-up strategies could reduce inter-center variability and help detect complications early. "  [Collapse]
Zeng Y, Zhang JW, Yang J. Endoscopic management of infected necrotizing pancreatitis: Advancing through standardization. World J Gastroenterol 2025; 31(20): 107451
4
"I read a very interesting article "Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A ..."  [Read more]
"I read a very interesting article "Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A systematic review and meta-analysis" (Meta-Analysis). The authors of the article presented a perfect analysis of the list of references in accordance with the PRISMA system. The article is devoted to the effectiveness of using artificial intelligence for recognizing colonoscopic images. The authors confirmed a higher efficiency in recognizing colon neoplasms using artificial intelligence than endoscopists. "  [Collapse]
Wang SY, Gao JC, Wu SD. Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A systematic review and meta-analysis. World J Gastroenterol 2025; 31(21): 105753
5
"The authors describe the role of molecular genetic, subtypes, application of organoid and treatment options in colorectal cancer very ..."  [Read more]
"The authors describe the role of molecular genetic, subtypes, application of organoid and treatment options in colorectal cancer very effectively and with nicely labelled illustrations. The role of artificial intelligence in managing colorectal cancer in evolving and holds a considerable role in identifying markers and defining management in coming years. "  [Collapse]
Qi GX, Zhao RX, Gao C, Ma ZY, Wang S, Xu J. Recent advances and challenges in colorectal cancer: From molecular research to treatment. World J Gastroenterol 2025; 31(21): 106964
6
"The title of this article is not only novel but also accurately reflects the scope and focus of the content presented. It captures ..."  [Read more]
"The title of this article is not only novel but also accurately reflects the scope and focus of the content presented. It captures the reader’s attention while maintaining consistency with the study’s objectives and findings. Additionally, the references are cited appropriately, demonstrating thorough literature review and academic rigor throughout the manuscript. "  [Collapse]
Wang WX, Dang FL, Li TT, Yu Y. Nalbuphine vs sufentanil as effective analgesics for postoperative pain management in gastric cancer resection. World J Gastrointest Pharmacol Ther 2025; 16(2): 103232
7
"This article discusses the importance of perioperative nutritional support and prehabilitation in patients undergoing gastrointestinal ..."  [Read more]
"This article discusses the importance of perioperative nutritional support and prehabilitation in patients undergoing gastrointestinal surgery. Perioperative nutritional support includes care before, during, and after surgery. Comprehensive nutritional support programs improve immune function and wound healing, and shorten the length of hospital stay. Prehabilitation enhances the patient's condition before surgery and reduces the risk of complications. Future research needs to identify the optimal combination and amount of nutritional components. However, the paper does not specifically mention GLIM (Global Leadership Initiative on Malnutrition). Nevertheless, the importance of nutritional support throughout the document, as well as the evaluation and improvement of nutritional status before and after surgery, may align with the improvement goals of GLIM. Further investigation is warranted. "  [Collapse]
Triantafillidis JK. Perioperative nutritional support in patients undergoing gastrointestinal surgery: Current views with an emphasis on prehabilitation efforts. World J Gastrointest Surg 2025; 17(6): 101244
8
"This study presents significant findings regarding the metabolic effects of esophagectomy with gastric conduit reconstruction, ..."  [Read more]
"This study presents significant findings regarding the metabolic effects of esophagectomy with gastric conduit reconstruction, particularly in T2D patients. Although the observed remission rate is modest compared to bariatric surgery outcomes, it opens up a new avenue for exploring the potential benefits of esophagectomy on metabolic health, especially in patients with comorbid diabetes. The study provides evidence that the use of a narrow gastric tube during esophagectomy might contribute to better diabetes outcomes, offering a potential modification to surgical practice that could improve patient care and prognosis. "  [Collapse]
Xing HJ, Hu MY, Jiang YQ, Li XH, Zhu B, Wang ZQ. Remission of type 2 diabetes one year after esophagectomy with gastric conduit reconstruction: A prospective cohort study. World J Gastrointest Surg 2025; 17(6): 105514
9
"The topic of perioperative nutritional support is highly relevant, particularly in the context of enhancing patient recovery and ..."  [Read more]
"The topic of perioperative nutritional support is highly relevant, particularly in the context of enhancing patient recovery and reducing postoperative complications. Given the increasing focus on improving surgical outcomes through preoperative interventions, this manuscript addresses a critical aspect of patient care. This paper underscores the importance of perioperative nutritional interventions and their potential to significantly improve postoperative outcomes, including reduced complications, shorter hospital stays, and faster recovery. Given the high rates of malnutrition and postoperative complications in gastrointestinal surgery patients, this review is highly significant for improving clinical practice. While the article touches on prehabilitation, the section could delve deeper into the specific methods of implementation and the practical challenges faced in clinical settings. A more detailed discussion of how to integrate prehabilitation into routine clinical practice, especially in less resource-rich environments, would add value for practitioners looking to apply these strategies. "  [Collapse]
Triantafillidis JK. Perioperative nutritional support in patients undergoing gastrointestinal surgery: Current views with an emphasis on prehabilitation efforts. World J Gastrointest Surg 2025; 17(6): 101244
10
"This review article is a really helpful and up-to-date look at how PET/CT scans using FDG are used for bile duct cancer (BTC). The ..."  [Read more]
"This review article is a really helpful and up-to-date look at how PET/CT scans using FDG are used for bile duct cancer (BTC). The authors do a great job pulling together the latest research, especially focusing on the past three years. They carefully examine how well PET/CT works for the different types of BTC – like cancers inside the liver (ICC), near the liver's exit (PCC), further down the bile duct (DCC), and gallbladder cancer (GBC). This breakdown is important because each type behaves differently. A key point the review makes is comparing PET/CT to standard scans like CT or MRI. PET/CT is generally better at finding cancer spread to lymph nodes, even if they aren't enlarged, and at spotting distant cancer spread elsewhere in the body. This can be crucial for planning treatment and avoiding unnecessary surgeries. However, the review honestly points out that PET/CT isn't perfect. It can sometimes miss smaller bile duct cancers (especially PCC) or cancers that produce a lot of mucus. It can also give "false alarms" due to inflammation, infection, or the presence of stents. The article highlights a significant shift happening: moving beyond just looking at the pictures to actually measuring things from the scan. Measurements like how "hot" the cancer appears (SUVmax) or the total amount of active cancer (MTV, TLG) can help doctors predict how aggressive the cancer might be and how long patients might live. Even more exciting is brand new research showing these PET/CT measurements might give clues about the cancer's genetics (like KRAS mutations in ICC) without needing a new biopsy. The review also covers advanced computer analysis of the scans (radiomics and AI), which shows promise in predicting things like how likely the cancer is to invade blood vessels or come back after surgery, especially for ICC. The authors also touch on the potential of combining PET with MRI (PET/MRI). This newer technology might offer better pictures of the soft tissues around the bile ducts and gallbladder, which could be useful for seeing exactly where the cancer is locally or if it has come back. However, more studies are needed, particularly for gallbladder cancer. Overall, this is a very valuable summary. It clearly explains where PET/CT is most useful right now for BTC patients – mainly in accurate staging to find hidden spread and guide treatment choices. It also effectively shows where the field is heading: using the scan data more precisely to understand the cancer's biology and predict outcomes, paving the way for more personalized care. The balanced view of both the strengths and weaknesses of PET/CT makes this review practical for doctors and informative for researchers looking at the future of imaging for these difficult cancers. "  [Collapse]
Yin JX, Fan X, Chen QL, Chen J, He J. Progress in the application of fludeoxyglucose positron emission tomography computed tomography in biliary tract cancer. World J Hepatol 2025; 17(5): 105446
11
"This bibliometric study systematically examines artificial intelligence applications in hepatobiliary surgery from 2014-2024, offering ..."  [Read more]
"This bibliometric study systematically examines artificial intelligence applications in hepatobiliary surgery from 2014-2024, offering a quantitative perspective on this evolving field. The research effectively maps global publication patterns, collaborative networks, and research priorities. The title accurately defines the scope, while the abstract concisely summarizes objectives, methodology, and key findings. Keywords demonstrate appropriate thematic alignment, and the background section adequately contextualizes AI's integration into hepatobiliary practice, noting its clinical relevance for diagnostic and therapeutic applications. Methodologically, the study employs Web of Science data with visualization tools (CiteSpace/VOSviewer) to analyze authorship, institutional contributions, national productivity, and keyword evolution. However, the search strategy shows limitations through its predominant focus on "CNN" (Convolutional Neural Networks), overlooking emerging architectures like Transformer models that are gaining prominence in medical AI research. Results clearly demonstrate China's leadership in publication volume alongside the United States' influence in citation impact, with network visualizations effectively illustrating these geographical patterns. The discussion reasonably outlines AI's role in imaging diagnostics and tumor segmentation, though greater analytical depth regarding clinical implementation challenges - such as model validation requirements and integration with surgical workflows - would strengthen its practical relevance. Presentation issues require attention as Figure 3 suffers from resolution limitations affecting text legibility, while Figures 10-11 contain non-essential graphical elements that reduce interpretive clarity. Strategic labeling could enhance data communication in these visualizations. Statistical approaches are appropriately applied for bibliometric analysis, and referenced literature shows generally authoritative coverage. Minor language issues exist, including inconsistent quotation usage in the abstract (e.g., "classification", "CT and "diagnosis") and occasional terminology variations, though these do not substantially hinder comprehension. Collectively, this work provides a structured, data-informed overview of AI research in hepatobiliary surgery during the specified decade. It documents the field's development trajectory, identifies primary research themes and key contributors, and establishes baseline patterns of international collaboration. The analysis offers researchers a useful reference point for understanding current research landscapes and potential partnership opportunities. With refinements addressing methodological scope, analytical depth, and visual presentation, the study could serve as a more comprehensive benchmark for future investigations in this domain. "  [Collapse]
Zheng RJ, Li DL, Lin HM, Wang JF, Luo YM, Tang Y, Li F, Hu Y, Su S. Bibliometrics of artificial intelligence applications in hepatobiliary surgery from 2014 to 2024. World J Gastrointest Surg 2025; 17(5): 104728
12
"The he article is well-written, and the research methodology is scientifically rigorous. The article holds significant scientific ..."  [Read more]
"The he article is well-written, and the research methodology is scientifically rigorous. The article holds significant scientific value and clinical relevance in the research of stem cell therapies for retinal pigment epithelium (RPE) cells. I hope the authors will address the current challenges in future studies, advancing the application of stem cell therapies in the treatment of RPE-related diseases. Thank you once again for your outstanding contributions to this field. "  [Collapse]
Sorrentino FS, Parmeggiani F, Gardini L, Fontana L, Musa M, Gagliano C, Zeppieri M. Stem cell therapy for retinal pigment epithelium disorders. World J Stem Cells 2025; 17(5): 103100
13
"Title: A Critical Appraisal of Dissociative Psychosis and Dissociative Schizophrenia as Distinct Entities Body: Having reviewed the ..."  [Read more]
"Title: A Critical Appraisal of Dissociative Psychosis and Dissociative Schizophrenia as Distinct Entities Body: Having reviewed the article titled "Are dissociative psychosis and dissociative schizophrenia reality?" by H. Belli, I am compelled to offer a commentary that reflects on the conceptualization and clinical significance of these conditions. The article presents a comprehensive analysis of dissociative phenomena within the context of psychotic disorders, challenging readers to reconsider the boundaries between dissociative and schizophrenic experiences. Belli's work prompts a reevaluation of the diagnostic criteria and the potential overlap between dissociative symptoms and schizophrenia. The discussion on the role of childhood trauma as a precipitating factor for dissociative experiences that may manifest as psychotic symptoms is particularly noteworthy. It suggests a bio-psycho-social model that could enhance our understanding of the etiology and comorbidity of these disorders. The article also underscores the importance of psychometric testing in identifying dissociative features in individuals with psychotic disorders. This approach could potentially lead to more personalized and effective treatment strategies, emphasizing the need for a trauma-informed care framework. In conclusion, Belli's article contributes to a growing body of research that questions the traditional dichotomy between dissociative and psychotic disorders. It advocates for a more integrated view that recognizes the complexity of mental health conditions and the impact of early life experiences on later psychiatric outcomes. I look forward to future studies that build on these insights and further explore the implications for clinical practice and mental health policy. Reviewer: Lu Hou "  [Collapse]
Belli H. Are dissociative psychosis and dissociative schizophrenia reality? World J Psychiatry 2025; 15(4): 102008
14
"This study by Wang et al. presents a compelling advancement in the noninvasive prediction of variceal bleeding risk in Budd-Chiari ..."  [Read more]
"This study by Wang et al. presents a compelling advancement in the noninvasive prediction of variceal bleeding risk in Budd-Chiari syndrome (BCS) patients using a combined radiomics and clinical model (R+C model). The integration of high-dimensional radiomics features with clinical parameters to stratify bleeding risk is both innovative and clinically relevant. The authors should be commended for conducting a multicenter study with an external validation cohort, which strengthens the generalizability of their findings. Strengths of the Study: Innovative Use of Radiomics: The application of radiomics in BCS—a relatively rare and under-studied condition—represents a novel contribution. The extraction of hepatic and splenic texture features from CT images enhances the predictive capability beyond conventional clinical models. Robust Methodology: The use of LASSO Cox regression for feature selection and validation of the model using an external cohort adds credibility. The model’s performance metrics, such as the C-index (0.906 for training and 0.859 for validation), demonstrate excellent discriminative ability. Clinical Utility: The development of an accessible online tool for individualized risk prediction (https://bcsvh.shinyapps.io/BCS_Variceal_Bleeding_Risk_Tool/) is a practical step towards clinical translation, potentially aiding in decision-making for prophylactic interventions. Risk Stratification: The ability to categorize patients into low-, medium-, and high-risk groups offers a framework for personalized management strategies, which could reduce unnecessary interventions in low-risk patients and prioritize high-risk individuals for aggressive preventive therapies. Limitations and Areas for Improvement: Retrospective Design: As with all retrospective studies, the potential for selection bias and unmeasured confounding exists. Prospective validation in diverse populations, including Western cohorts where thrombophilic etiologies of BCS predominate, is necessary. Limited Radiomics Scope: The use of single-slice regions of interest (ROIs) for liver and spleen may not capture the full heterogeneity of these organs. A volumetric or multi-slice approach could improve robustness. Generalizability: The study population is entirely Chinese, with BCS cases predominantly due to membranous obstruction—an etiology not common in other geographic regions. Thus, external validation in populations with differing BCS etiologies is crucial. Anticoagulation Risk Interpretation: While anticoagulation was found to be an independent risk factor for bleeding, the model does not differentiate between anticoagulant types or dosing strategies. Given the importance of anticoagulation in BCS, further work is needed to clarify safe therapeutic windows. Manual Segmentation: The reliance on manual ROI delineation is resource-intensive and may limit scalability. Incorporating semi-automated or AI-driven segmentation could enhance reproducibility and feasibility in routine clinical settings "  [Collapse]
Wang ZD, Nan HJ, Li SX, Li LH, Liu ZC, Guo HH, Li L, Liu SY, Li H, Bai YL, Dang XW. Development and validation of a radiomics-based prediction model for variceal bleeding in patients with Budd-Chiari syndrome-related gastroesophageal varices. World J Gastroenterol 2025; 31(19): 104563
15
"I read a very interesting manuscript. The authors propose to use Hericium erinaceus to regress gastric mucosal atrophy. The authors ..."  [Read more]
"I read a very interesting manuscript. The authors propose to use Hericium erinaceus to regress gastric mucosal atrophy. The authors present convincing evidence of the effectiveness of this medicine. Prevention of gastric cancer has several successive stages of implementation (detection of precancerous diseases and precancerous changes in the gastric mucosa, implementation of screening, diagnostics, verification of diagnosis by morphological methods and treatment). Preventive treatment of precancerous lesions has a very limited number of means and methods. I believe that it is necessary to continue studying and using Hericium erinaceus. Perhaps Hericium erinaceus will be an effective drug for the prevention of gastric cancer. "  [Collapse]
Pellegrino R, Gravina AG. Potential of traditional Chinese medicine in gastrointestinal disorders: Hericium erinaceus in chronic atrophic gastritis. World J Gastroenterol 2025; 31(20): 106615
16
"This paper systematically analyzes the etiology of the two major subtypes of inflammatory bowel disease (IBD): Crohn’s disease and ..."  [Read more]
"This paper systematically analyzes the etiology of the two major subtypes of inflammatory bowel disease (IBD): Crohn’s disease and ulcerative colitis. It is highly comprehensive and commendable. It examines the etiology broadly, focusing on immune responses and considering genetic changes, gut microbiota, and social and environmental factors. On the other hand, further discussion is needed regarding how concretely these theoretical insights into etiology are linked to the development of therapeutic approaches. Additionally, genetic factors and changes in gut microbiota can vary by region, making universal evaluation difficult. "  [Collapse]
Yang QH, Zhang CN. Comparative study on the pathogenesis of Crohn’s disease and ulcerative colitis. World J Gastroenterol 2025; 31(19): 106406
17
"This minireview article provides a systematic comparison of the pathogenic mechanisms of Crohn’s disease and ulcerative colitis. It ..."  [Read more]
"This minireview article provides a systematic comparison of the pathogenic mechanisms of Crohn’s disease and ulcerative colitis. It outlines six shared mechanisms—including immune dysregulation, genetics, microbiota imbalance, and infections—and identifies 14 key differences between the two diseases. The article is well-structured, comprehensive in scope, and supported by clear diagrams, offering strong academic value and clinical relevance. While its originality and depth of mechanistic insight could be further improved and the discussion on clinical translation is somewhat limited, it remains a well-organized and information-rich review suitable for researchers and clinicians alike. "  [Collapse]
Yang QH, Zhang CN. Comparative study on the pathogenesis of Crohn’s disease and ulcerative colitis. World J Gastroenterol 2025; 31(19): 106406
18
"This article explores the role of the "obesity paradox" in immunotherapy for hepatocellular carcinoma (HCC), suggesting that obese ..."  [Read more]
"This article explores the role of the "obesity paradox" in immunotherapy for hepatocellular carcinoma (HCC), suggesting that obese patients may experience better survival outcomes when treated with immune checkpoint inhibitors such as lenvatinib and camrelizumab. Based on recent clinical findings, the authors discuss leptin-mediated immune modulation as a possible mechanism, noting that obesity may enhance the efficacy of anti-PD-1 therapies but potentially reduce the effectiveness of anti-VEGF treatments. While the topic is novel and clinically relevant, the current evidence remains limited and the mechanistic explanation could be more detailed. Overall, the article provides a valuable perspective on the dual role of obesity in HCC immunotherapy and highlights the need for further research in this area. "  [Collapse]
Sierra L, Abu-Hammour MN, Chatterjee A, Simons-Linares CR. Obesity paradox role in the immunosuppressive treatment of hepatocellular carcinoma. World J Gastroenterol 2025; 31(19): 105617
19
"Reader′s comments: We are delighted to read the interesting article by Hu et al entitled: "Pescadillo ribosomal biogenesis factor ..."  [Read more]
"Reader′s comments: We are delighted to read the interesting article by Hu et al entitled: "Pescadillo ribosomal biogenesis factor 1 and programmed death-ligand 1 in gastric and head and neck squamous cell carcinoma"it is an interesting study, but we have some comments: In section of patients selection: exclusion criteria: it is not clear what was meant by pathological condition????? I think it is better to represent demographic , clinical data of enrolled patients. Result section: it is better to clear if difference between positive and negative patients is significant or not. What about expression of the studied markers in adjacent non tumor tissues???????? "  [Collapse]
Hu XN, Li CF, Huang SM, Nie CL, Pang R. Pescadillo ribosomal biogenesis factor 1 and programmed death-ligand 1 in gastric and head and neck squamous cell carcinoma. World J Gastroenterol 2025; 31(19): 106644
20
"Shukla et al.'s comprehensive review on remnant pancreatic carcinoma (RPC) brings much-needed attention to a rare but clinically ..."  [Read more]
"Shukla et al.'s comprehensive review on remnant pancreatic carcinoma (RPC) brings much-needed attention to a rare but clinically formidable entity increasingly recognized in the era of improved surgical outcomes and long-term survival following partial pancreatectomy. Their work, titled "Remnant Pancreatic Carcinoma: The Current Status", outlines the epidemiology, risk factors, surveillance strategies, and therapeutic challenges of RPC, providing a valuable clinical framework for a condition historically relegated to case reports and small series. The authors astutely emphasize the evolving landscape of RPC, shaped by the growing volume of patients undergoing distal or proximal pancreatectomy for benign or malignant lesions. The incidence of RPC is likely underestimated, given limited long-term follow-up in most cohorts. As such, the article's call for structured postoperative surveillance protocols is particularly timely. Importantly, Shukla et al. underscore that remnant pancreatic malignancies may arise de novo or as recurrences, and often present with more aggressive histological and molecular profiles, reinforcing the need for tailored risk stratification. A notable strength of this review is its discussion on the putative mechanisms underlying RPC, including genetic predisposition, field cancerization, and chronic inflammation of the residual gland. These insights are crucial for identifying high-risk patients who may benefit from enhanced surveillance or prophylactic strategies. However, while the authors reference KRAS and TP53 mutations, a more extensive exploration of genomic drivers and their potential as surveillance biomarkers would have added translational depth. Surgically, re-resection remains the mainstay of curative intent in selected patients with adequate functional reserve. The article appropriately highlights the technical and oncological complexities of completion pancreatectomy. Nonetheless, future perspectives might benefit from the integration of evolving minimally invasive approaches and neoadjuvant strategies tailored to RPC biology. One of the article’s understated yet significant contributions is its implication that RPC represents a failure of current surveillance paradigms. Given the shift towards parenchyma-sparing resections and increased survivorship, integrating longitudinal imaging and biomarker monitoring—such as circulating tumor DNA (ctDNA) or CA 19-9 kinetics—may optimize early detection. Moreover, data on long-term outcomes post-remnant resection remain sparse, and prospective registries are needed to define survival benchmarks and refine selection criteria. In conclusion, Shukla et al. succeed in framing RPC not merely as a post-surgical curiosity, but as a distinct oncological entity warranting multidisciplinary attention. Their review lays the foundation for future clinical and translational studies in a domain poised to grow in relevance. Establishing consensus on definitions, risk stratification algorithms, and surveillance protocols will be essential to improving outcomes in this uniquely challenging subset of pancreatic cancer. "  [Collapse]
Shukla A, Kalayarasan R, Sai Krishna P, Pottakkat B. Remnant pancreatic carcinoma: The current status. World J Clin Oncol 2025; 16(5): 107039
971 items  Read more >>
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