Baishideng Publishing Group

Chen X, Sun XH, Xiao Y, Zhang D, Lu XY, Fu CL, Bi C, Wang X. Efficacy and safety of transarterial chemoembolization with chemotherapy, PD-1/PD-L1 inhibitors, and tyrosine kinase inhibitors in unresectable intrahepatic cholangiocarcinoma. World J Gastrointest Oncol 2025; 17(9): 103816

"During the review process of the manuscript, the opinions provided by the reviewers were very practical. They helped me improve many ..." [Read more]

"During the review process of the manuscript, the opinions provided by the reviewers were very practical. They helped me improve many deficiencies in the article, expand the research scope, and increase the richness of the paper. I am extremely grateful for your assistance. At the same time, I would like to express my sincere gratitude to the editors for their hard work.Best wishes to you. " [Collapse]

Sun TF, Fan KX, Luo YX, Song J, Han ZX, Zhang XL. Relationship between uric acid and colon cancer risk: Dose-response analysis and mechanisms. World J Gastrointest Oncol 2025; 17(9): 107651

"A very rigorous and intensive peer review was prepared by the journal. The journal interface for revision submission was also very ..." [Read more]

"A very rigorous and intensive peer review was prepared by the journal. The journal interface for revision submission was also very extensive and detailed, but smooth. The manuscript proofreading process was also detailed and minute. The overall quality of the PDF produced is also excellent. We are thankful to the editorial team for such a pleasant experience. " [Collapse]

Gupta S, Lal N, Pradhan A, Verma AK. Association of chronic periodontitis in a broad spectrum of cardiometabolic syndrome: A minireview. World J Cardiol 2025; 17(9): 109126

"The publication time was relatively long (4 months). I think the journal should target reducing the time between acceptance and ..." [Read more]

"The publication time was relatively long (4 months). I think the journal should target reducing the time between acceptance and publication. It is understandably that if quality will be better, it may take longer time. Nevertheless, increasing the staff may shorten this time which can increase the citation of the manuscript. " [Collapse]

Abu-Zidan FM, Idris K, Cevik AA. Management of earthquake-related acute renal injury. World J Nephrol 2025; 14(3): 107201

"I wish express our profound appreciation to the entire stakeholders of the World Journal of Nephrology for extending their kind ..." [Read more]

"I wish express our profound appreciation to the entire stakeholders of the World Journal of Nephrology for extending their kind invitation and accepting our proposed manuscript title and abstract in the first instance. The editorial process from the submission to the publication was exciting and filled with a great and worthwhile experience. You have maintained a satisfactory ethical standard worthy of emulation by other peer-reviewed Journal. " [Collapse]

Khalid A, Yakubu KB, Umar AM, Aljannare BG, Aminu NA, Obadele OG, Abdulwahab-Ahmed A. Uncommon presentation and management of a giant renal cyst abscess: A case report. World J Nephrol 2025; 14(3): 108703

"World Journal of Nephrology has a robust and reasonably good peer-review process. It offers a viable and credible venue for publication ..." [Read more]

"World Journal of Nephrology has a robust and reasonably good peer-review process. It offers a viable and credible venue for publication for researchers, especially in the field of nephrology. The journal is committed to ethical standards, timely processing, external review, and clarity in author instructions. I suggest that there will be public peer-review reports on the journal website in the future. " [Collapse]

Tran TTT, Tran KV, Nguyen TD, Pham NTT, Nguyen TH. Role of heat shock proteins in renal function and adaptation to heat stress: Implications for global warming. World J Nephrol 2025; 14(3): 107571

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your ..." [Read more]

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your prestigious PubMed Journal. We are very much obliged for the great efforts done by the reviewers, editors and the publication team. Their actions had greatly improved the overall scientific and academic quality of our manuscript upto highest international standards. Hopefully this unique manuscript will garner lots of citation in the scientific community. Thanks for the opportunity. Best Regards, Dr . Arvind Kumar Morya MS(Gold Medalist) MNAMS Additional Professor & Unit-I Head Cataract, Glaucoma, Refractive, Squint Paediatric Ophthalmology and Medical Retina Services Associate Editor UKJOS, National Advisor IJO,GJCSRO Editorial Board Member IJOVS, WJCC, EC-Ophthalmology, DOS Times, Journal of HOS. Reviewer Elsevier, AIMDR and IJO Clinical Trial Expert Panel - CDSCO & Ministry of Health and Family Welfare Convenor - AIOS Adverse Event Committee Department of Ophthalmology All India Institute of Medical Sciences, Bibinagar Hyderabad, Telangana -508126 INDIA +91-8003996598 " [Collapse]

Menia NK, Morya AK, Gupta PC, Ramachandran R. Ocular biomarkers in diabetes mellitus with diabetic kidney disease: A minireview. World J Nephrol 2025; 14(3): 109470

"I wish to express my sincere appreciation to you, the editorial office, and all reviewers for the exceptional collaboration throughout ..." [Read more]

"I wish to express my sincere appreciation to you, the editorial office, and all reviewers for the exceptional collaboration throughout the peer-review process of my manuscript. Your professionalism, clear guidance, and timely communication greatly facilitated revisions and improvement. The quality of feedback and supportive correspondence not only improved the scientific rigor of my work but also made the experience highly constructive. I am grateful for the care and dedication you invest in your role. " [Collapse]

Kapritsou M. Intersection of medicine and nursing in endoscopic sedation: Understanding roles and responsibilities. World J Gastrointest Endosc 2025; 17(9): 110664

"It was a pleasant experience working on this manuscript, as the peer review committee was prompt to respond and always gave good ..." [Read more]

"It was a pleasant experience working on this manuscript, as the peer review committee was prompt to respond and always gave good feedback for improvement. From editing to proofreading to the online portal system to make changes, all the processes were seamless. I thoroughly enjoyed my time working with the committee to get this manuscript to be published and would recommend the same committee to any aspiring author. " [Collapse]

Majmundar V, Deo R, Mishra AK, Li PY, Byer M, Sancassani R. Transcatheter atrial septal defects and patent foramen ovale closure: Medicare utilization and reimbursements. World J Methodol 2025; 15(4): 103146

"We received many thoughtful and highly appropriate comments from the reviewers. Through the revision process, I truly felt that the ..." [Read more]

"We received many thoughtful and highly appropriate comments from the reviewers. Through the revision process, I truly felt that the manuscript was continuously refined and improved. Moreover, I was amazed by the prompt handling after the revision and that the acceptance was reached within just a matter of days. I am deeply grateful for the journal’s swift and appropriate response. " [Collapse]

Sugiyama Y, Tanabe K, Yanagawa S, Tazawa H, Toyota K, Kano M, Misumi T, Shishida M, Okano K, Hotta R, Ota H, Imaoka Y, Fukuda T, Takahashi S, Ohdan H. Prognostic factors and efficacy of postoperative chemotherapy in patients with gastric cancer with positive peritoneal cytology after gastrectomy. World J Gastrointest Oncol 2025; 17(9): 110245

"This journal offers a rapid review process, and the reviewers provide fair and constructive comments. The figures and tables prepared ..." [Read more]

"This journal offers a rapid review process, and the reviewers provide fair and constructive comments. The figures and tables prepared by the authors are well-formatted and easily editable. It would be even better if the time from manuscript receipt to online publication could be further shortened. In short, this journal is a worthwhile venue for scholars engaged in gastrointestinal cancer research. " [Collapse]

Zhan TA, Xia F, Huang HW, Zhan JC, Liu XK, Cheng Q. Fibroblast growth factor 19-fibroblast growth factor receptor 4 axis: From oncogenesis to targeted-immunotherapy in advanced hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(9): 108649

"I would like to sincerely thank the editorial team and peer reviewers for their professional and constructive support throughout the ..." [Read more]

"I would like to sincerely thank the editorial team and peer reviewers for their professional and constructive support throughout the entire publication process. The peer review comments were insightful and helped to significantly improve the quality and clarity of our manuscript. The editorial handling was efficient, transparent, and highly professional, resulting in a smooth and rewarding publication experience. I am very satisfied with the overall process and would be pleased to recommend this journal to my colleagues. " [Collapse]

Kim JH, Na HY, Jung K, Jang D, Youn Y, Kim DH, Han HD, Hwang JH. Quantitative immunohistochemistry analysis of pancreatic adenocarcinoma upregulated factor expression in pancreatic cancer and its prognostic significance. World J Gastrointest Oncol 2025; 17(9): 109055

"This was an exceptional publication experience from start to finish. The journal's reputation for rigorous scholarship is ..." [Read more]

"This was an exceptional publication experience from start to finish. The journal's reputation for rigorous scholarship is well-deserved, as evidenced by the insightful and constructive comments from the reviewers, which greatly enhanced our manuscript. The editorial team was remarkably efficient and communicative at every stage, ensuring a smooth and transparent process. The rapid transition from acceptance to online publication is also highly commendable. I would look forward to submitting future work. " [Collapse]

Zhang X, Chen DB, Zhang R, Chen P, She SP, Yang Y, Ren LY, Chen HS. Immune checkpoint molecules signal regulatory protein alpha in the development of hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(9): 109824

"I would like to express my sincere appreciation to the editorial team for their highly efficient handling of my manuscript. The ..." [Read more]

"I would like to express my sincere appreciation to the editorial team for their highly efficient handling of my manuscript. The peer-review process was both rigorous and exceptionally swift, with constructive feedback that significantly improved the quality of the work. Moreover, the time from acceptance to online publication was remarkably short, reflecting the journal’s strong commitment to rapid dissemination of high-quality research. It has been a truly smooth and rewarding experience publishing in this journal. " [Collapse]

Qiu ZS, Wang XC, Ma JC, Zhu CL, Hu YL, Da MX. DEAD/H-box RNA helicase 10 promotes pancreatic cancer cell proliferation via ribonucleotide reductase M2. World J Gastrointest Oncol 2025; 17(8): 108672

"My experience with this journal’s acceptance process was largely positive. The initial submission was streamlined via its user-friendly ..." [Read more]

"My experience with this journal’s acceptance process was largely positive. The initial submission was streamlined via its user-friendly online portal, with clear guidelines reducing confusion. Post-submission, the status updates were timely, so I never felt in the dark. The peer reviews, though rigorous, were constructive—suggestions focused on strengthening arguments rather than nitpicking. After I revised the manuscript, the editorial team responded promptly, finalizing the acceptance within two weeks. Minor hiccups, like a short delay in one review, were negligible. Overall, the process was transparent and efficient, showing the journal’s respect for authors’ work. " [Collapse]

Deng QX, Tang XL, Yuan GJ, Jian Q, Chen XH, Wu LJ. Study of serum tumor markers in the early diagnosis of pancreatic cancer. World J Gastrointest Oncol 2025; 17(9): 106910

"Thank you for giving us the opportunity to provide feedback on our recent publication experience (Manuscript NO. 109378). Overall, ..." [Read more]

"Thank you for giving us the opportunity to provide feedback on our recent publication experience (Manuscript NO. 109378). Overall, I am very satisfied with my publishing experience in the World Journal of Gastrointestinal Oncology. Below is our detailed evaluation: 1.Efficient editorial processing: The manuscript was promptly sent for peer review after submission, and status updates were provided in a timely manner at every stage. Communication from the editors was clear, professional, and supportive throughout the decision-making process. 2.High-quality review comments: The reviewers provided exceptionally constructive and insightful feedback. Although addressing their comments required considerable effort, their critiques greatly enhanced the scientific rigor and narrative clarity of our paper. 3.Rapid publication speed: The production process following acceptance was remarkably efficient, resulting in swift online publication. This rapid dissemination is vital for the timely sharing of our findings with the research community. 4.Online System Interface: The online submission system functions adequately. However, each resubmission currently overwrites the previous version of the manuscript. It would greatly improve the user experience if the interface could retain a record of all submitted versions. We are very satisfied with our experience publishing in the World Journal of Gastrointestinal Oncology. The rigorous peer review process and efficient production are hallmarks of a high-quality journal. Thank you again for your hard work. " [Collapse]

Pu BP, Wang PH, Guo KK, Liu C, Chen SR, Li XM, Chen SM, Zeng XZ, Gao C. Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming. World J Gastrointest Oncol 2025; 17(9): 109378

"The publication process for my article went smoothly from start to finish. When I encountered small questions about document formatting ..." [Read more]

"The publication process for my article went smoothly from start to finish. When I encountered small questions about document formatting or submission progress, the editorial team replied promptly with clear guidance. The peer review steps were also well-organized and followed a regular timeline, making the whole experience straightforward and without unnecessary delays. " [Collapse]

Xiong FC, Luo MP, Ruan SM. Construction of a risk prediction model for early postoperative recurrence in stage II/III colorectal cancer. World J Gastrointest Oncol 2025; 17(9): 107968

"I am thoroughly satisfied with the peer review process provided by this journal. The reviewers' comments were exceptionally thorough, ..." [Read more]

"I am thoroughly satisfied with the peer review process provided by this journal. The reviewers' comments were exceptionally thorough, insightful, and constructive. They demonstrated a deep understanding of the subject matter and provided critiques that significantly strengthened the manuscript's clarity and scientific rigor. The entire process was handled with remarkable professionalism and timeliness by the editorial team, making the revision phase both productive and intellectually rewarding. This experience was highly positive, and I would not hesitate to recommend this journal to my colleagues for its exemplary peer review standards. " [Collapse]

Xue RX, Lu XY, Deng P, Wang LH, Yun YF. Misdiagnosis of gastric oxyntic gland adenoma as hyperplastic polyp: A case report. World J Gastrointest Oncol 2025; 17(9): 110505

"The journal editor has been extremely supportive throughout the submission and review process, providing helpful guidance and ..." [Read more]

"The journal editor has been extremely supportive throughout the submission and review process, providing helpful guidance and facilitating a smooth communication. Likewise, the reviewers offered constructive and genuinely encouraging comments that highlighted the strengths of the manuscript while also suggesting valuable improvements. Their feedback significantly enhanced the overall quality of the work. I am sincerely grateful for their efforts, and I would like to express my heartfelt thanks for all the contributions and support provided during this process. " [Collapse]

Kirkik D, Ozabaci AN, Kalkanli Tas S. Changing patterns of cholangiocarcinoma and gallbladder cancer: A regional perspective from Northeastern Italy. World J Gastrointest Oncol 2025; 17(9): 108578

"First of all, thank the editor for his hard work. The overall submission process of your magazine is fair and transparent. The opinions ..." [Read more]

"First of all, thank the editor for his hard work. The overall submission process of your magazine is fair and transparent. The opinions and suggestions put forward by peer review experts are very professional. We have gained a lot in the process of submission. If there are suitable articles in the future, we will continue to contribute to your magazine. " [Collapse]

Gao Z, Zhang JX, Tian XD, Wu SK, Jin X. Rapid cholestasis improvement as key strategy for steroid-refractory immune-related cholangitis: A case report. World J Gastrointest Oncol 2025; 17(9): 108960

19493 items Read more >>

Article Quality Tracking-Peer-Review

"Although the disease is very rare nowadays, the article's information looks meaningful and informative. I have witnessed this disease ..." [Read more]

"Although the disease is very rare nowadays, the article's information looks meaningful and informative. I have witnessed this disease in goats but not in humans. The published article has raised very good concerns by picking up this topic. This is the only way to get information about the disease, as it is very rare, or almost never witnessed by several doctors. In the article, the authors have very nicely discussed the pathogenicity and other aspects. " [Collapse]

Ismail A, Abdelsalam MA, Shahin MH, Ahmed Y, Bahcecioglu IH, Yalniz M, Tawheed A. Hepatobiliary fascioliasis: A neglected re-emerging threat, its diagnostic and management challenges. World J Gastrointest Pathophysiol 2025; 16(2): 107599

"This study innovatively applied ResNet to the hepatic congestion signs in conventional CT, further diagnosing congestive liver ..." [Read more]

"This study innovatively applied ResNet to the hepatic congestion signs in conventional CT, further diagnosing congestive liver diseases, and has clear value for early warning of liver injury in patients with HF. The methodology is rigorous, and it has confirmed that AI can assist in the early identification of TR-related liver injury. In the next step, it is necessary to expand the sample to verify the generalization, and strengthen the clinical transformation design." [Collapse]

Miida S, Kamimura H, Fujiki S, Kobayashi T, Endo S, Maruyama H, Yoshida T, Watanabe Y, Kimura N, Abe H, Sakamaki A, Yokoo T, Tsukada M, Numano F, Kashimura T, Inomata T, Fuzawa Y, Hirata T, Horii Y, Ishikawa H, Nonaka H, Kamimura K, Terai S. Image analysis of cardiac hepatopathy secondary to heart failure: Machine learning vs gastroenterologists and radiologists. World J Gastroenterol 2025; 31(34): 108807

"This article focuses on esophageal GIST, a rare disease type (accounting for only 0.5% of all GIST cases), and systematically reviews ..." [Read more]

"This article focuses on esophageal GIST, a rare disease type (accounting for only 0.5% of all GIST cases), and systematically reviews the potential of endoscopic resection techniques (ESD/STER/EFTR) to replace the highly invasive esophageal resection surgery. The next supplementary content includes: supplementing with endoscopic image evidence to clarify technical details; adding treatment strategies for special populations (children/immunosuppressed individuals); discussing the potential application of robot-assisted endoscopy." [Collapse]

Krishnamoorthy A, Griffiths EA. Endoscopic resection of oesophageal gastrointestinal stromal tumours: Promise, pitfalls and the path forward. World J Gastroenterol 2025; 31(34): 110448

"This article focuses on the expanded application of the ALBI score in non-malignant liver diseases, systematically reviewing its ..." [Read more]

"This article focuses on the expanded application of the ALBI score in non-malignant liver diseases, systematically reviewing its clinical value as an objective tool for liver function assessment. Its limitations lie in: inability to assess the degree of liver fibrosis; being affected by non-liver factors such as hemolysis and sepsis; and decreased reliability in cases of end-stage liver disease combined with renal failure." [Collapse]

Demirors B, Shekouhi R, Jimenez PB, Yadav A, Chiriboga G, Mahesh VA, Manaise HK, Bowers J, Merly AA, Gabriel E. Redefining the albumin-bilirubin score: Predictive modeling and multidimensional integration in liver and systemic disease. World J Gastroenterol 2025; 31(34): 110602

"This article systematically integrates the latest evidence-based evidence for the imaging assessment of anorectal fistula type Crohn's ..." [Read more]

"This article systematically integrates the latest evidence-based evidence for the imaging assessment of anorectal fistula type Crohn's disease (pCD), and for the first time proposes a multi-modal imaging stratified decision-making pathway, providing individualized solutions for different medical resource scenarios. The possible future directions include: developing an ultrasound scoring system; implementing AI models to adapt to portable ultrasound devices for use at the grassroots level; and remote image monitoring." [Collapse]

Habeeb H, Chen L, De Kock I, Bhatnagar G, Kutaiba N, Vasudevan A, Srinivasan AR. Imaging in perianal fistulising Crohn’s disease: A practical guide for the gastroenterologist. World J Gastroenterol 2025; 31(34): 110611

"This study innovatively applied SR reconstruction to the prediction of liver cancer pathological grading, confirming that SR-MRI can ..." [Read more]

"This study innovatively applied SR reconstruction to the prediction of liver cancer pathological grading, confirming that SR-MRI can enhance the prediction efficacy of liver cancer pathological grading. The method is rigorous and the conclusion is reliable, providing a new idea for radiomics. However, it is necessary to strengthen the design of clinical transformation pathways and the exploration of biological mechanisms. The next step should focus on prospective validation and multi-omics integration." [Collapse]

Wang ZZ, Song SM, Zhang G, Chen RQ, Zhang ZC, Liu R. Multiparametric magnetic resonance imaging of deep learning-based super-resolution reconstruction for predicting histopathologic grade in hepatocellular carcinoma. World J Gastroenterol 2025; 31(34): 111541

"A transjugular intrahepatic portosystemic shunt (TIPS) is one of the most challenging procedures in interventional radiology. Hepatic ..." [Read more]

"A transjugular intrahepatic portosystemic shunt (TIPS) is one of the most challenging procedures in interventional radiology. Hepatic and portal venous anatomy can vary greatly, and access to the portal vein, which can be quite difficult even for experienced surgeons, is the most critical step in a TIPS. Despite the fact that there are many techniques for clearly identifying the relevant anatomic structures during TIPS creation, each of them carries a unique set of risks and benefits. Thus, knowledge of these techniques will empower the surgeon in planning and subsequently performing a TIPS and, ultimately, increase the likelihood of a safe and successful procedure." [Collapse]

Miao L, Ren JL, Zhao H, Li X. Optimal guiding methods for transjugular intrahepatic portosystemic shunt creation: Characteristics of intravascular ultrasound vs other techniques. World J Hepatol 2025; 17(8): 109496

"It was with pleasure that I tracked the quality of the following article. Please see my comments below: 1 Ethics: Not applicable ..." [Read more]

"It was with pleasure that I tracked the quality of the following article. Please see my comments below: 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: The figures/tables enhance the readability of the manuscript 5 Biostatistics: Not applicable given manuscript type 6 References: The references are appropriate/up-to-date 7 Language: This is a well-thought out comprehensive manuscript 8 Caveats or drawbacks: None " [Collapse]

"This retrospective multicenter study aimed to investigate the type and rate of complications in patients undergoing SBE as well as ..." [Read more]

"This retrospective multicenter study aimed to investigate the type and rate of complications in patients undergoing SBE as well as the risk factors responsible for the occurrence of these complications. The rate of complications (0.4%) was very low and concerned intestinal perforation, which was detected in all cases during the endoscopy. The treatment was surgical in all patients, and the outcome was favorable. The main risk factor for the occurrence of this complication was previous abdominal surgery and excessive abdominal pressure during endoscopy. SBE performed by experienced endoscopists is a remarkably safe method and should be applied in all cases of occult gastrointestinal bleeding. Endoscopists should be particularly careful in patients with previous surgery, in which the application of abdominal pressure is often necessary. In my opinion, this second reason is the most important for the occurrence of this complication. Gastroenterologists-endoscopists should be particularly careful when requesting the application of abdominal pressure during endoscopy. " [Collapse]

Ullah S, Bai YQ, Wareesawetsuwan N, Cui LL, Danzhu YJ, Wang K, Zhu SS, He X, Cao XG, Guo CQ, Zhang FB. Complications of single-balloon enteroscopy: A nine-year multicenter experience of 2865 procedures. World J Gastroenterol 2025; 31(34): 110548

""A total of 179 patients with chronic HF who underwent echocardiography between 2011 and 2020 were included. These patients underwent ..." [Read more]

""A total of 179 patients with chronic HF who underwent echocardiography between 2011 and 2020 were included. These patients underwent CT within 1 year before or after echocardiography; blood samples were collected within 6 months of imaging. The severity of right HF was classified into three groups (mild, moderate, and severe) based on a comprehensive echocardiographic assessment. Selected patient's diseases are unclear. Did authors select the patients who have ischemic coronary diseases, congenital heart diseases, or valvular diseases? Methods are new." [Collapse]

"This is very interesting paper.The hepatic venous pressure gradient serves as a crucial parameter for assessing portal hypertension ..." [Read more]

"This is very interesting paper.The hepatic venous pressure gradient serves as a crucial parameter for assessing portal hypertension and predicting clinical decompensation in individuals with cirrhosis. However, owing to its invasive nature, there has been growing interest in identifying noninvasive alternatives. Noninvasive models utilizing SSM, LSM, and SLD are effective in predicting clinical decompensation among patients with viral cirrhosis, I agree to author's opinion. " [Collapse]

Yang LB, Gao X, Xu M, Li Y, Dong L, Huang XD, She X, Zhang DY, Zhang QW, Liu CY, Fan ST, Wang Y. Noninvasive model based on liver and spleen stiffness for predicting clinical decompensation in patients with cirrhosis. World J Gastroenterol 2025; 31(33): 107408

"This is a timely, comprehensive, and clinically valuable systematic review of photon-counting CT in oncologic imaging. The manuscript ..." [Read more]

"This is a timely, comprehensive, and clinically valuable systematic review of photon-counting CT in oncologic imaging. The manuscript successfully synthesizes evidence across multiple cancer types and highlights both opportunities and limitations of this emerging technology. Major revisions suggested: Add a tabular summary of included studies with key characteristics. Clarify methodological limitations (lack of risk-of-bias assessment, single database). Explicitly state that ethical approval was not required. Minor revisions suggested: Streamline language in highly technical sections. Expand limitations regarding cost, accessibility, and inter-institutional standardization." [Collapse]

Perera Molligoda Arachchige AS, Dashiell A, Jesuraj AS, D’Urso AI, Fiore B, Cattaneo M, Pierzynska E, Szydelko S, Centini FR, Verma Y. Applications of photon-counting CT in oncologic imaging: A systematic review. World J Radiol 2025; 17(8): 107732

"The manuscript is well-structured, comprehensive, and provides clinically relevant insights that will be highly valuable for both ..." [Read more]

"The manuscript is well-structured, comprehensive, and provides clinically relevant insights that will be highly valuable for both radiologists and clinicians involved in the diagnosis and management of diverticulitis. The content is organized logically, covering epidemiology, classification systems, imaging findings, complications, and emerging directions such as artificial intelligence. The language is generally clear and precise, making the article accessible to its intended audience. Minor revisions are recommended to further strengthen the paper. Specifically, polishing a few sentences for clarity and conciseness would enhance readability. Since the manuscript is a review and does not involve direct patient data or interventions, it would be appropriate to explicitly state that ethical approval was not required, in order to meet standard publishing practices. In addition, the discussion could be expanded to address potential caveats or limitations, such as interobserver variability in CT interpretation, the ongoing debate regarding conservative versus surgical management, and the challenges in differentiating diverticulitis from malignancy in certain cases. Addressing these points will improve the balance of the manuscript and provide readers with a more nuanced understanding of the topic." [Collapse]

Simsar M, Yuruk YY, Sahin O, Sahin H. Radiological insights into diverticulitis: Clinical manifestations, complications, and differential diagnosis. World J Radiol 2025; 17(8): 107463

"The advent of machine learning has revolutionized gastrointestinal endoscopy. However, many challenges remain to be overcome before ..." [Read more]

"The advent of machine learning has revolutionized gastrointestinal endoscopy. However, many challenges remain to be overcome before its clinical application, including data dilemmas, algorithm complexity, and ethical dilemmas. Further technological innovation and standardization of endoscopic image data are expected to enable AI to perform everything from diagnosis to personalized treatment, across all endoscope manufacturers." [Collapse]

Ding JC, Zhang J. Endoscopic image analysis assisted by machine learning: Algorithmic advancements and clinical uses. Artif Intell Gastrointest Endosc 2025; 6(3): 108281

"Objectivity The article demonstrates strong objectivity by adopting a balanced "current status-issues" framework, without one-sidedly ..." [Read more]

"Objectivity The article demonstrates strong objectivity by adopting a balanced "current status-issues" framework, without one-sidedly overstating research progress on glioblastoma multiforme (GBM). It systematically outlines the application value of imaging technologies such as MRI (with T1-weighted contrast enhancement for visualizing tumor necrosis) and PET (with 18F-FET for distinguishing recurrence from radiation necrosis), while also clearly pointing out limitations like the poor soft tissue contrast of CT and the need for a nearby cyclotron for 11C-methylmethionine (11C-MET). When elaborating on the standard "surgery + radiotherapy + temozolomide (TMZ)" regimen, it simultaneously highlights the therapeutic bottleneck that the 5-year survival rate remains only 4.6%-5.6%. Literature screening covers multiple databases including MEDLINE, with studies up to February 2025 included in accordance with PRISMA guidelines, avoiding selective inclusion of positive results. It also maintains a neutral stance when discussing controversies in AI applications (e.g., low proficiency of doctors in operating AI tools) and does not shy away from technical flaws. Credibility The credibility is constrained by the peer review results (with scientific quality, innovation, and other indicators all rated Grade D), but there are still supporting elements. The authors are affiliated with the Department of Medical Imaging and Radiation Sciences, University of Sherbrooke, Canada; the corresponding author is a professor and contact information is provided. Literature citations are standardized, including DOI and PMID, and Tables 1-3 clearly summarize key data such as imaging tracers and chemotherapeutic drugs, with a reproducible PRISMA process. However, the single-blind review (involving only one expert from Japan) may lead to a limited perspective, and the article does not mention data replication and verification, which weakens part of its credibility. Scientific Quality As a review article, its scientific quality is moderate. Its strengths lie in a clear structure, progressing logically from "epidemiology-imaging-treatment-AI," with each conclusion supported by literature (e.g., citing Zheng et al.’s AI study using 40 million samples). It also compares the advantages and disadvantages of different imaging modalities and treatment regimens, providing references for clinical practice. Nevertheless, there are shortcomings: it fails to quantify key indicators (such as AI segmentation accuracy), describes research data on emerging nanodrugs and PARP inhibitors in a vague manner, and does not analyze diagnostic and therapeutic differences among different molecular subtypes (e.g., IDH-mutant GBM), resulting in insufficient scientific depth. Resolved Issues The article clarifies regional differences in GBM epidemiology, applicable scenarios of mainstream imaging and treatment regimens, and constructs an application framework for AI in GBM, providing systematic knowledge for beginners. It also identifies core bottlenecks such as the blood-brain barrier and difficulties in early detection, defining the research scope. Unresolved and Existing Issues It does not propose specific biomarkers for early detection (e.g., circulating tumor cells), fails to quantify data on the generalizability of AI models, provides ambiguous solutions for multi-center collaboration and data privacy protection, and does not discuss personalized diagnosis and treatment strategies for different molecular subtypes. Future Solutions The authors mention that future efforts should focus on strengthening structured validation and ethical oversight of AI. Specifically, multi-center collaboration can be conducted to establish a standardized imaging database and carry out prospective AI trials; subtype-specific treatment models can be developed by integrating genomic data; and early screening schemes combining "AI + biomarkers" can be explored to fill current research gaps." [Collapse]

Bentourkia M, Abdo RA. Updates on glioblastoma multiforme: From epidemiology to imaging and artificial intelligence. Artif Intell Med Imaging 2025; 6(2): 108032

"Objectivity: The article avoids bias by balancing AI’s strengths and limitations. It details AI’s value (e.g., 3D vascular mapping ..." [Read more]

"Objectivity: The article avoids bias by balancing AI’s strengths and limitations. It details AI’s value (e.g., 3D vascular mapping cutting DIEP flap surgery time, AR navigation improving osteotomy accuracy) while explicitly noting barriers like data variability and surgeon unfamiliarity. Literature selection follows PRISMA, retrieves 4 databases up to Feb 2025, and is PROSPERO-registered (CRD420251008741), with no selective inclusion of positive results. Credibility: Backed by external single-blind peer review (experts from China, Saudi Arabia, Türkiye) with specific gradings (scientific quality mostly Grade B, novelty Grade A-C). Authors (e.g., Harvard-affiliated Ryan P Cauley) have authoritative backgrounds; citations include DOI/PMID, and the PRISMA flow diagram (104 screened, 64 excluded, 27 included) ensures reproducibility. Scientific Quality: As a narrative review, it integrates systematic review elements (pre-registration, standardized retrieval). Results are structured by clinical scenarios (preoperative planning, etc.), each supported by studies (e.g., Le et al.’s 2023 deep learning research). The discussion links technical flaws to clinical risks (e.g., sensor inaccuracy causing missed flap ischemia) and compares AI maturity across fields. Resolved Issues: Clarified AI’s application scope in plastic surgery imaging, established a framework for analyzing AI challenges, and set methodological benchmarks for similar reviews via PRISMA/PROSPERO compliance. Unresolved Issues: Lacks quantification of data variability, cross-population model validation, plastic surgery-specific AI regulatory paths, and details on surgeon AI training. Also has potential peer-review bias, imbalanced literature timeliness, and insufficient ethical/technical transparency. Proposed Solutions: The author implies future focus on structured validation and ethical oversight. To address gaps, multi-center standardized databases, collaboration with regulators for tailored frameworks, surgeon training programs, and supplementary technical/ethical materials are needed." [Collapse]

Yamin MA, Raquepo TM, Tobin M, Posso AN, Cauley RP. Applications and challenges of artificial intelligence in plastic surgery imaging: A narrative review. Artif Intell Med Imaging 2025; 6(2): 108028

"The mini-review addresses the multifunctional roles of the CD47/SIRPα pathway, emphasizing its implications in immunity, homeostasis, ..." [Read more]

"The mini-review addresses the multifunctional roles of the CD47/SIRPα pathway, emphasizing its implications in immunity, homeostasis, and cancer therapeutics. The subject is highly relevant to biomedical research and clinical translation, and the manuscript provides an extensive overview of molecular mechanisms, cellular functions, and therapeutic strategies. The article is timely, given the increasing interest in immune checkpoint modulation and anti-CD47 therapies. The review is well structured, with clear sections covering molecular mechanisms, cellular functions, and clinical implications. The inclusion of schematic figures and summary tables is helpful, though some illustrations could be improved in resolution and annotation to make complex signaling pathways easier to follow. The manuscript successfully integrates both classical and recent literature, including clinical trial data, which strengthens its scientific significance. The references are numerous, updated, and appropriate, reflecting a good command of the field. However, the methodology for literature selection is not described, and this reduces transparency compared to systematic approaches. The language is generally clear and concise, with good readability, although a few sentences could be shortened to improve flow. The main caveat is that the article tends to be descriptive rather than analytical. In some sections, especially those on therapeutic implications, the review could benefit from a more critical discussion of controversies, limitations, and unresolved challenges, such as on-target toxicity and resistance mechanisms. Explicitly highlighting knowledge gaps would enhance the review’s impact. Overall, this is a well-prepared review on a clinically relevant topic. It effectively summarizes the multifunctional roles of CD47/SIRPα and provides a useful resource for readers. With minor revisions to strengthen the critical analysis and presentation of figures, the manuscript is suitable for publication and may attract significant interest from the field." [Collapse]

Bhardwaj N, Chandra H, Singh A, Babu R. CD47/SIRPα pathways: Functional diversity and molecular mechanisms. World J Biol Chem 2025; 16(3): 108045

"The manuscript presents a comprehensive metabolomic analysis of Gardenia jasminoides fruits collected from different provenances in ..." [Read more]

"The manuscript presents a comprehensive metabolomic analysis of Gardenia jasminoides fruits collected from different provenances in Hunan Province, China. The topic is relevant to natural product chemistry and pharmacognosy, and the use of UHPLC-MS/MS combined with antioxidant assays adds methodological strength. The description of the experimental setup is detailed and generally sufficient to allow reproducibility, which is a positive aspect. The results are well-supported by data, including PCA, HCA, and correlation analyses, and the conclusions appear consistent with the findings. The figures and tables are informative and mostly well-designed, although some chromatograms and heatmaps could benefit from improved labelling and clarity for international readers. The statistical approaches are appropriate, with adequate use of replicates and validation steps. The interpretation of antioxidant assays is clear, although the biological significance could be expanded beyond correlations with geniposide, crocin, and chlorogenic acid. The references are adequate but somewhat regionally focused. Including more international comparative studies on plant metabolomics and bioactivity would increase the article’s global relevance. The language is acceptable overall, but there are occasional grammatical issues and awkward expressions that could be improved by careful editing. Limitations include the fact that only one geographic region was sampled, which may limit generalizability. Moreover, the study is restricted to antioxidant capacity without further validation of pharmacological activity. Addressing these limitations in the discussion would strengthen the article. In conclusion, this is a valuable contribution to the metabolomics characterization of medicinal plants, with solid methodology and reliable results, though with moderate impact due to its regional scope. The manuscript is suitable for publication after minor language polishing and some improvement in discussion of broader implications." [Collapse]

Bi WY, He WL, Wang W, Wang XR, Zhou ZJ, Zeng YL. Chemical composition differences in wild Gardenia jasminoides fruits across provenances using metabolomics. World J Biol Chem 2025; 16(3): 105875

"Thank you for pointing to the some key issues remaining unresolved till now in this area of research. Standard clinical trials, a ..." [Read more]

"Thank you for pointing to the some key issues remaining unresolved till now in this area of research. Standard clinical trials, a more holistic approach, including epigenetics, the assessment of genetic association analyses are necessary for a thorough understanding of potential pitfalls, including ethnic and/or even cultural differences. Sand PG, Poeppl TB, Roessler V. Unmet needs in precision psychiatry. World J Psychiatry 2025; 15(9): 108222 [DOI: 10.5498/wjp.v15.i9.108222] " [Collapse]

Sand PG, Poeppl TB, Roessler V. Unmet needs in precision psychiatry. World J Psychiatry 2025; 15(9): 108222

"Dear authors, thank you for this article, it points to a very important topic to open up mentalization based interventions or ..." [Read more]

"Dear authors, thank you for this article, it points to a very important topic to open up mentalization based interventions or mindfulness-based stress reduction. Emotional awareness and nonjudgmental present-moment awareness to foster adaptive coping strategies is a very promising parameter for professionals. Further research is very much needed, thank you for opening up this topic in your review. Zhou RR, Chen LL, Lin LD. Mindfulness-based stress reduction and mental health in department of emergency nurses: A narrative review. World J Psychiatry 2025; 15(9): 107630 [DOI: 10.5498/wjp.v15.i9.107630]" [Collapse]

Zhou RR, Chen LL, Lin LD. Mindfulness-based stress reduction and mental health in department of emergency nurses: A narrative review. World J Psychiatry 2025; 15(9): 107630

15792 items Read more >>

Peer-Reviewers and Manuscript Statistics

Editorial board members: 2264

Peer-reviewers: 33598

Manuscripts received today: 27

Manuscript reviews today: 51

Unhandled manuscripts today: 140

Active peer-reviewers today: 2158

Reviewer acceptance today: 78

Reviewer refusals today: 83

Total accepted manuscripts: 37725

Total rejected manuscripts: 43027

Total peer-reviewers: 4370656

Total submissions: 35853