Baishideng Publishing Group

Wang Z, Cheng JW, Yu KY. Short-term and long-term effects of sevoflurane inhalation vs propofol total intravenous anesthesia in gastrectomy for gastric cancer. World J Gastrointest Oncol 2025; 17(11): 109375

"In preparing the revision, we noted that the online submission system requires text, figures, and tables to be entered into separate ..." [Read more]

"In preparing the revision, we noted that the online submission system requires text, figures, and tables to be entered into separate fields. We are concerned that this process may inadvertently introduce formatting errors, particularly for complex equations, schematics, and multi-panel figures, which could affect the clarity and accuracy of our work. To ensure the highest possible presentation quality and to avoid any potential for error, we would be grateful if we could submit our revised manuscript as a single, unified Word document (or PDF) file. This file has been carefully formatted and contains all text, figures, tables, and captions in their correct context and layout. We believe this will greatly facilitate an accurate and efficient review process. Thank you for considering this request. " [Collapse]

Liu YM, Du YY, Song Y, Xiong HT, Yu HB, Li BH, Cai L, Ma SS, Gao J, Zhang HY, Fang RY, Cai R, Zheng HG. Predicting chemotherapy-induced myelosuppression in colorectal cancer: An interpretable, machine learning-based nomogram. World J Gastroenterol 2025; 31(42): 112180

"I would like to express my sincere appreciation for the insightful comments provided by the reviewers. Their thorough and constructive ..." [Read more]

"I would like to express my sincere appreciation for the insightful comments provided by the reviewers. Their thorough and constructive feedback was invaluable in strengthening the manuscript. The rigorous assessment has undoubtedly enhanced the quality and clarity of our work, and we are grateful for the editors' and reviewers' dedication. " [Collapse]

Wang XY, An F, Wang BJ, Han WW. Hydrogen peroxide pathway in ulcerative colitis: Promises and challenges in translating novel pathogenesis to clinical practice. World J Gastroenterol 2025; 31(42): 112566

"We sincerely appreciate the professional and efficient editorial and publication process of the World Journal of Gastroenterology. ..." [Read more]

"We sincerely appreciate the professional and efficient editorial and publication process of the World Journal of Gastroenterology. The editorial team and reviewers provided constructive and timely feedback, which greatly improved the quality of our manuscript. We are deeply grateful for their hard work, dedication, and rigorous attitude throughout the publication process. We look forward to continued cooperation with the journal in the future. " [Collapse]

Xu Y, Hao JW, Min CC, Yang L, Ma CP, Shi C, Mao T, Tian ZB, Wang T, Yu YN. Precision therapy guided by genotypic antibiotic resistance for Helicobacter pylori eradication: A prospective, randomized controlled trial. World J Gastroenterol 2025; 31(42): 110717

"I am pleased to report that the peer review process has been immensely beneficial to my manuscript. The reviewers' insights were not ..." [Read more]

"I am pleased to report that the peer review process has been immensely beneficial to my manuscript. The reviewers' insights were not only constructive but also provided a comprehensive perspective that greatly enhanced the quality of my work. I found their feedback to be fair and objective, addressing key areas that needed improvement without bias. Their suggestions were clear and actionable, which has led to a more robust and coherent final version of my manuscript. I am grateful for the thorough and professional review, and I believe the suggestions have significantly contributed to the academic integrity and readability of my research. " [Collapse]

Liu WJ, Zhao YM, Xie QQ, Wu MC, Pan YF, Yan HK, Shan XX, Xu WT, Liu YL, Peng CX, Zhang XM, Lin Q. Multistrain probiotics alleviate gastrointestinal symptoms during bismuth quadruple therapy for Helicobacter pylori infection. World J Gastroenterol 2025; 31(42): 112577

"To the Editorial Office of World Journal of Gastroenterologyand Baishideng Publishing Group, Dear Editors and Publishing Team, We ..." [Read more]

"To the Editorial Office of World Journal of Gastroenterologyand Baishideng Publishing Group, Dear Editors and Publishing Team, We are delighted to announce the successful online publication of our manuscript in the World Journal of Gastroenterology. Through this journey, we have been deeply impressed by the exceptional quality, professionalism, and author-centric approach of your journal and publishing system. We would like to extend our sincere appreciation and admiration for your outstanding work. 1. Prestigious Journal with Remarkable Academic Influence As a leading authority in the field of gastroenterology, the World Journal of Gastroenterologyhas earned widespread recognition for its high academic standards, as reflected in its Q1 ranking, impressive Impact Factor (4.3 in 2024), and CiteScore (7.8). The journal consistently publishes cutting-edge research that drives the discipline forward, providing an invaluable platform for scholars worldwide. 2. Highly Professional and Efficient Editorial Team From submission to acceptance, we experienced a seamless and transparent process guided by a dedicated and professional editorial team. The peer review was rigorous and constructive, while the language and production editors demonstrated meticulous attention to detail, significantly enhancing the quality of our manuscript. The inclusion of author evaluations and post-publication quality tracking further underscores your commitment to continuous improvement and academic excellence. 3. User-Friendly F6Publishing System and Exceptional Author Services The F6Publishing system is a model of efficiency and user-friendliness. Its intuitive interface, real-time status updates, and integrated features—such as CrossCheck plagiarism screening and online copyright agreements—streamlined the entire publication process. The responsive Help Desk support promptly addressed any queries, ensuring a smooth and stress-free experience for authors. 4. Strong Commitment to Publishing Ethics and Open Science Your adherence to open access principles (under the Creative Commons license) facilitates the broad dissemination of knowledge. The journal’s strict ethical standards, along with initiatives like the Baishideng Distinguished Award, demonstrate a deep commitment to scientific integrity and innovation. Moreover, the encouragement of reader comments and fee-waived Letters to the Editor reflects an inclusive and collaborative academic culture. 5. Forward-Thinking Vision and Leadership Baishideng’s innovative use of technology, such as the Reference Citation Analysis (RCA) system, and the strategic development of a diverse journal portfolio (including other Q1/Q2 titles like World Journal of Diabetesand World Journal of Psychiatry) highlight your leadership in the evolving landscape of academic publishing. The well-organized website and author resources further enhance accessibility and usability. Conclusion Our experience with the World Journal of Gastroenterologyhas been nothing short of exceptional. Your journal is not only a disseminator of knowledge but also a genuine partner in the research journey. We are confident that under your leadership, the journal will continue to achieve new heights. We look forward to future collaborations and wish you ongoing success. Warm regards, The Author Team November 13, 2025 " [Collapse]

Wang FF, Dai XD, Zhao X, He Q, Lyu SC. Development and validation of a predictive model for portal-systemic venous invasion grading in borderline resectable pancreatic cancer. World J Gastroenterol 2025; 31(42): 112354

"We are deeply honored that our manuscript has been accepted for publication in your esteemed journal, which is widely recognized for ..." [Read more]

"We are deeply honored that our manuscript has been accepted for publication in your esteemed journal, which is widely recognized for its high academic standards and significant influence in the field. The entire editorial process, from initial review to final decision, was handled with remarkable efficiency and professionalism. We are especially grateful for the thorough and constructive feedback provided by the reviewers. Their valuable insights and the editors' clear guidance were instrumental in refining our work, and we believe this collaborative process is a hallmark of a leading scholarly publication. " [Collapse]

Sun YS, Bai XQ, Sun KD, Li J, Liu L, Chen YY, Zeng ZY, Wang Q, Guo YB. Thymosin β4 released by mast cells under stress conditions impairs intestinal epithelial barrier via IL22RA1/JAK1/STAT3 signaling in irritable bowel syndrome. World J Gastroenterol 2025; 31(42): 111706

"I was highly satisfied with the overall editorial and peer-review process. The peer reviewers provided exceptionally logical, precise, ..." [Read more]

"I was highly satisfied with the overall editorial and peer-review process. The peer reviewers provided exceptionally logical, precise, and scientifically well-grounded critiques that clearly strengthened the quality and clarity of the manuscript. Their comments were constructive, methodologically sound, and directly relevant to the core clinical and pathological issues addressed in the case report. In addition, the handling editor facilitated the process with remarkable efficiency. The editorial decisions were timely, and the guidance provided at each stage accurately reflected the authors’ intentions and helped refine the final version of the manuscript without compromising its scientific integrity. I particularly appreciated the editor’s careful consideration of the authors’ responses and the balanced manner in which revisions were coordinated. Overall, the combination of rigorous peer review and responsive editorial management resulted in a smooth and highly professional publication experience. I am grateful for the opportunity to publish in this journal and look forward to future submissions. " [Collapse]

Jung HS, Kim HJ, Kim KW. Early pleuroparenchymal fibroelastosis mimicking lung malignancy: A case report. World J Clin Cases 2025; 13(32): 111879

"The manuscript submission site is very user friendly and seamless. The peer review process was punctual, swift and detailed. The ..." [Read more]

"The manuscript submission site is very user friendly and seamless. The peer review process was punctual, swift and detailed. The quality of the final PDF is great, and the proofreading process was meticulous, too. The overall publication experience with the journal was very pleasant. I would love to submit another manuscript. " [Collapse]

Verma AK, Vats Y, Bajpai J, Kar SK, Pradhan A, Kant S. Pulmonary tuberculosis in diabetes: Exploring the intersection and impact on mental health. World J Clin Cases 2025; 13(32): 110154

"The editorial and peer review process was highly efficient and transparent, and the reviewers' suggestions were exceptionally ..." [Read more]

"The editorial and peer review process was highly efficient and transparent, and the reviewers' suggestions were exceptionally constructive. The editorial office demonstrated remarkable professionalism and thoroughness in their work. We extend our sincere gratitude to all the staff at the journal.However, we have one question: since the article has already been accepted, why were repeated revisions still required? Additionally, we would like to suggest updating the submission system to make it more modern and user-friendly. " [Collapse]

Yu WX, Zhan FF, Hong PY, Huang MH, Chen YY, Lin YL, Zhang XB. Atypical sarcoidosis diagnosed using endobronchial ultrasound-guided mediastinal lymph node biopsy with fine biopsy forceps: Two case reports. World J Clin Cases 2025; 13(32): 111525

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working ..." [Read more]

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working with BPG. The reviewing process needs work. It takes numerous months before reviewers are found. The system could be improved by slimlining the entire submission process. Other journals take 1-2 for complete publication. " [Collapse]

Zeppieri M, Nicolosi SG, D’Esposito F, Musa M, Avitabile A, Gagliano C, Battista M, Barboni P, Capobianco M. Beyond the optic disc: Investigating gender-based differences in optic neuritis. World J Clin Cases 2025; 13(32): 111134

"The journal’s reputation for excellence is clearly reflected in your team’s dedication, and I truly appreciate the effort put into ..." [Read more]

"The journal’s reputation for excellence is clearly reflected in your team’s dedication, and I truly appreciate the effort put into ensuring a smooth and successful publication. Thank you for your hard work and support—it has been a pleasure working with you. I look forward to future opportunities to contribute to your esteemed journal. " [Collapse]

Xie GL, Heng J, Jia XF, Li Q, Chang R, Zhang N, Xie LL, Gao C. Image and intracavitary electrocardiogram-guided arm port placement in colorectal cancer: A retrospective comparative study. World J Gastrointest Surg 2025; 17(10): 109407

"We sincerely thank the Editors and staff of the World Journal of Hepatology for their careful review and efficient handling of our ..." [Read more]

"We sincerely thank the Editors and staff of the World Journal of Hepatology for their careful review and efficient handling of our manuscript, and for providing an important platform to promote innovative therapeutic strategies for decompensated cirrhosis. This protocol represents one of the early, systematically designed randomized controlled studies evaluating empagliflozin, a sodium-glucose cotransporter 2 inhibitor, in patients with cirrhosis and refractory ascites, with a clear focus on natriuretic efficacy, safety and patient-centered outcomes. We firmly believe that, with the accumulation of robust clinical evidence, the value of SGLT2 inhibitors in the management of ascites in decompensated cirrhosis will be progressively confirmed and translated into meaningful benefits " [Collapse]

Gao Y, Gao YY, Shi RY, Ji D, Wang Y, Xu L, Wang Q, Wu MH, You HL, Bu QS, Dong YX, Zhou LZ, Liu W, Song QK, Han Y, Wei H, Zhang XY, Hu ZJ. Effect of empagliflozin on fractional excretion of sodium in patients with cirrhosis and refractory ascites. World J Hepatol 2025; 17(10): 110247

"I, with the coauthors thank for the consideration and the publication of our manuscript. The comment what we have for the journal ..." [Read more]

"I, with the coauthors thank for the consideration and the publication of our manuscript. The comment what we have for the journal for its future improvement is that the time from submission to reviewing and announcing the first decision is ideal. But coming to the time duration from the acceptance to the online publication is a bit longer. Though each journal has its own editorial time length, It will be better if a sort of improvement is made on the time from acceptance to the online publication to make the authors more satisfied with the service that they might get from the journal. " [Collapse]

Assefa AN, Haile JM, Woldearegay AG. Child vaccine communication practice in promoting child immunization in the Amhara region of Ethiopia. World J Clin Pediatr 2025; 14(4): 107333

"The editorial and peer review processes were efficient, transparent, and constructive. Reviewer feedback was insightful and greatly ..." [Read more]

"The editorial and peer review processes were efficient, transparent, and constructive. Reviewer feedback was insightful and greatly improved the quality of our manuscript. Communication with the editorial office was always timely, courteous, and professional. I sincerely appreciate the editors’ dedication and the journal’s commitment to maintaining high scientific and ethical publication standards. " [Collapse]

Koker G. Iron metabolism and sepsis-associated liver injury: Methodological considerations and clinical perspectives. World J Hepatol 2025; 17(8): 108474

"I really learned a lot from the peer review reports and comments, which guided me greatly in improving the manuscript Although the ..." [Read more]

"I really learned a lot from the peer review reports and comments, which guided me greatly in improving the manuscript Although the manuscript format and figure preparation were challenging, it was actually possible with the guide to authors and the critical reviewers' comments. The time from submission to online publishing was reasonable, and the follow-up from the editorial office and guidance were great " [Collapse]

Basiouny HEM, Allam SS, Allam AA, Abdelsattar S, Sira MM. Diagnostic and prognostic utility of D-dimer and heparin-binding protein in neonatal sepsis: A prospective case-control study. World J Clin Pediatr 2025; 14(4): 110776

"I would like to express my sincere appreciation to the editorial team for providing me with the opportunity to publish in your esteemed ..." [Read more]

"I would like to express my sincere appreciation to the editorial team for providing me with the opportunity to publish in your esteemed journal. The entire review and evaluation process was highly professional and efficient. The sequence of manuscript evaluation and the arrangement of the review timeline were well-organized and transparent. Communication with the editorial office was timely and clear, and the reviewers’ comments were constructive and insightful, greatly contributing to the improvement of the paper. Overall, I am extremely satisfied with the journal’s editorial management and review process. The rigorous yet efficient system reflects the journal’s high academic standards and strong commitment to scholarly excellence. I truly appreciate the efforts and professionalism of the editors and reviewers. " [Collapse]

Nima CL, Wang HG, Zhou Q. Pancreatic tuberculosis: A case report and review of literature. World J Gastroenterol 2025; 31(41): 110398

"Advantages: The submission system has a clear interface, explicit guidance, and logical upload steps. The review process is fast, ..." [Read more]

"Advantages: The submission system has a clear interface, explicit guidance, and logical upload steps. The review process is fast, with the first-round review time generally ranging from 1 to 3 months. Disadvantages: After acceptance, the journal does not offer related language editing services, and authors are also unable to freely choose other service providers for processing. The page charges are relatively high, and there is a hope that they could be reduced. " [Collapse]

Xie Q, Xin YC, Yang LH, Liu C, Tian ZD, Shang XL. Investigation of depressive symptoms after thyroid cancer surgery: Logistic regression analysis and adjustment strategy. World J Psychiatry 2025; 15(11): 110018

"Really, there is no much to add. The only thing would be about the reference's list system, which changed a bit our original list, ..." [Read more]

"Really, there is no much to add. The only thing would be about the reference's list system, which changed a bit our original list, including a pair of totally wrong references, with no relation with the subject of our article, but it was probably our problem by not correctly understanding the mechanism. Aside than that, no more to say. " [Collapse]

González Ferreira JA, Fernandez C, Gonsalves D, Paguey I, Couñago F. Radiotherapy treatment time delay evidence, part I: Update on cervical, anal, prostate, and head and neck cancers. World J Clin Oncol 2025; 16(10): 109247

"We would like to express our sincere gratitude to the editors and the anonymous reviewers for their constructive and thoughtful ..." [Read more]

"We would like to express our sincere gratitude to the editors and the anonymous reviewers for their constructive and thoughtful comments, which significantly improved the quality of this manuscript and strengthened this paper. The datasets generated and analyzed during the current study are available from the corresponding author on reasonable request. " [Collapse]

Zhao XF, Bi YX, Xiao S, Lou ML, Zhu WL, Xing YR. Chronotype as a risk factor for adolescent depression and anxiety: The mediating roles of sleep and social functioning. World J Psychiatry 2025; 15(11): 111593

19888 items Read more >>

Article Quality Tracking-Peer-Review

"1. The review provides a thorough and well-organized synthesis of the complex interplay between MASLD and IBD, with a strong emphasis ..." [Read more]

"1. The review provides a thorough and well-organized synthesis of the complex interplay between MASLD and IBD, with a strong emphasis on the gut microbiota and the gut-liver axis. The topic is highly relevant, given the rising global prevalence of both MASLD and IBD, and the growing recognition of their co-occurrence. The review successfully highlights the shift from a purely metabolic understanding of MASLD to one that incorporates gut-derived inflammation and dysbiosis, which is a crucial contemporary concept. 2. References：The authors have done an excellent job integrating a vast body of literature, making the manuscript a valuable and up-to-date resource for researchers and clinicians. 3. Language：The manuscript is generally well-written in clear and accessible English, which facilitates the comprehension of complex pathophysiological concepts. 4. Figures and tables：A significant shortcoming is the lack of detailed, mechanistic figures. The existing two figures are overly simplistic and do not adequately illustrate the complex molecular and cellular pathways discussed in the text (e.g., the roles of TLRs, bile acid receptors FXR/TGR5, Th17/Treg imbalance, cytokine networks, and the impact of specific microbial metabolites). I strongly recommend the inclusion of at least one high-quality, multi-panel schematic diagram that visually integrates the key proposed mechanisms linking gut dysbiosis, intestinal barrier dysfunction, immune activation, and hepatic inflammation/fibrosis in the context of IBD-associated MASLD. 5. Caveats or drawbacks： The manuscript contains several typographical and terminological errors that detract from its professionalism. For instance: On Page 4, the text reads "T17 cells play a key role..." This should be corrected to "Th17 cells..." as this is the standard nomenclature for T-helper 17 cells. While the content is comprehensive, there is some repetition between sections, particularly regarding the description of gut dysbiosis and its consequences in both IBD and MASLD. The flow could be improved by more sharply differentiating the disease-specific mechanisms before synthesizing them into a unified model. The sections on "Eating Behaviour Patterns" and "Nutrition-Microbiota Axis," while interesting, feel somewhat distinct from the core mechanistic focus and could be more seamlessly integrated. The treatment section briefly mentions probiotics, synbiotics, and cytokine inhibitors (IL-17/IL-23) but lacks depth in discussing the current evidence base, challenges, and future directions for these interventions. The review excellently describes associations but could more explicitly acknowledge the challenges in establishing causality within the gut-liver axis in human studies. In summary, this is a timely, informative, and largely well-executed review that makes a valuable contribution to the literature. Its primary strengths lie in its scholarly comprehensiveness and relevance. " [Collapse]

Sokal-Dembowska A, Ergan K, Jarmakiewicz-Czaja S. Role of gut microbiota in the development of metabolic dysfunction-associated steatotic liver disease in inflammatory bowel disease. World J Gastroenterol 2025; 31(40): 111375

"It is generally accepted that IBD results from the interaction of multiple environmental factors in genetically predisposed ..." [Read more]

"It is generally accepted that IBD results from the interaction of multiple environmental factors in genetically predisposed individuals, and that altered intestinal permeability is a key mechanism in the pathogenesis of the disease, as in many other digestive tract pathologies. Mitochondrial dysfunction in the intestinal mucosa is another mechanism involved in the pathogenesis of IBD. In the reviewed study, the authors examined the factor GDF15, a member of the TGF-β superfamily, as a biomarker of mitochondrial dysfunction and a mediator of UPRmt. The researchers confirmed elevated circulating GDF15 levels in IBD patients compared with healthy controls and identified a novel molecular mechanism by which this cytokine disrupts the intestinal barrier. Therefore, successfully reducing GDF15 may constitute a therapeutic strategy to prevent intestinal barrier breakdown by reducing immune hyperactivation in the future. All these basic research studies contribute decisively not only to elucidating the pathogenetic mechanisms of IBD but also to developing new therapeutic strategies that bring us closer to the day when we can achieve complete and sustained inhibition of IBD activity." [Collapse]

Ruiz-Malagón AJ, Herraiz-Vilela M, Serrano-Pino R, García-Ávila P, Díaz-Suárez L, Carmona-Segovia AD, Becerra-Munoz VM, Jiménez-Navarro M, Arranz-Salas I, López-Villodres JA, Fernández-Castañer A, Gutiérrez-Martínez F, Rodríguez-González FJ, Camargo-Camero R, Alcaín-Martínez G, Rodríguez-Díaz C, García-Fuentes E, Sánchez-Quintero MJ, López-Gómez C. Growth differentiation factor 15 alters intestinal barrier and increases permeability: A new molecular target in inflammatory bowel disease. World J Gastroenterol 2025; 31(41): 110955

"a fine-needle aspiration (FNA) biopsy, especially one guided by endoscopic ultrasound (EUS-FNA), is a valuable diagnostic tool for ..." [Read more]

"a fine-needle aspiration (FNA) biopsy, especially one guided by endoscopic ultrasound (EUS-FNA), is a valuable diagnostic tool for pancreatic tuberculosis. This procedure allows doctors to collect tissue samples to confirm the diagnosis by checking for characteristic signs like granulomas, caseous necrosis, and acid-fast bacilli (AFB) or by using polymerase chain reaction (PCR) to detect the DNA of Mycobacterium tuberculosis. EUS-FNA is especially useful because it can help differentiate pancreatic TB from pancreatic cancer, preventing unnecessary surgery. " [Collapse]

Nima CL, Wang HG, Zhou Q. Pancreatic tuberculosis: A case report and review of literature. World J Gastroenterol 2025; 31(41): 110398

"In this mini-review, the authors described the current understanding of the pathogenesis, diagnosis, and management of hepatic ..." [Read more]

"In this mini-review, the authors described the current understanding of the pathogenesis, diagnosis, and management of hepatic hydrothorax. Despite the successes of modern hepatology, the presence of hepatic hydrothorax is associated with poor prognosis and high mortality. Most patients with hepatic hydrothorax are candidates for liver transplantation. In usual clinical practice, the key to the success of their management may be the stratification of the risk of an adverse outcome and the definition of individual therapeutic tactics. A pathogenetically based approach to the choice of pharmacotherapy, as well as optimization of minimally invasive treatment methods, will improve the quality of life and increase the survival rate of this category of patients. In general, the authors provided well-known information." [Collapse]

Cilia BJ, Haridy J, Raj A, Hannah N. Hepatic hydrothorax as a manifestation of decompensated cirrhosis: An update on current management and future directions. World J Hepatol 2025; 17(10): 110412

"Dear Author There are parameters like MELD score that show the severity of the disease. This important score was not addressed ..." [Read more]

"Dear Author There are parameters like MELD score that show the severity of the disease. This important score was not addressed in the trial. Were the adherent and non-adherent groups had similar MELD scores? Sarcopenia as another important factor that influence cirrhosis out comes. This risk factor was not addressed in this trial. The nutritional status regarding the vitamins and protein intake are among the most important factors that influence cirrhosis out comes. In the future trials considering the variables that influence the patient outcomes should be considered. " [Collapse]

Loschi TM, Baccan MDTA, Pereira EC, Dellabarba TDLC, Boteon APCS, Boteon YL. Telerehabilitation for frail cirrhotic patients awaiting liver transplant: A safe, effective strategy to improve outcomes. World J Hepatol 2025; 17(10): 110856

"Dear Author, The patient had a history of cirrhosis of the liver based on abdominal CT scan. The data regarding the other causes ..." [Read more]

"Dear Author, The patient had a history of cirrhosis of the liver based on abdominal CT scan. The data regarding the other causes of chronic hepatitis were not included in the draft. Although using herbal medicine could cause the fulminant hepatitis, yet it is a diagnosis of exclusion. In my opinion, the possibility of coexistence of auto immune hepatitis in this case needs more evaluation." [Collapse]

Zhu XY, Zhao YT, Su CS, Yuan XD, Zhang SG, Nashan B. Acute liver failure caused by alkaloids from traditional Chinese medicine: A case report. World J Hepatol 2025; 17(10): 109575

"In recent years, artificial intelligence (AI) has brought about a real revolution in various fields of human activity, establishing ..." [Read more]

"In recent years, artificial intelligence (AI) has brought about a real revolution in various fields of human activity, establishing itself as a pioneering innovation in modern medical science. In the field of gastroenterology, and in particular colonoscopy, it has contributed significantly by promoting key quality indicators, reducing the rate of human error, and improving the consistency of endoscopist decision-making with high reliability. Reduce human error and improve endoscopists' decision-making consistency in real time, ensuring higher reliability and standardization during the procedure. By optimizing the characterization of endoscopically detected lesions, supporting visual diagnosis, and predicting the depth of infiltration, AI can enable early diagnosis and prevention of colon cancer. The combination of AI with advanced imaging techniques improves the quality of gastroenterologists' training. However, much remains to be clarified regarding the role of AI in upper and lower gastrointestinal endoscopy. I believe that the official gastroenterological societies of Europe, the USA, and Asia should immediately delve into studying and defining the possibilities, potential risks of the widespread application of the method, and define policies regarding quality assurance, clinician education, data protection, and liability, so that AI successfully complements human intelligence and experience. The innate tendency of people (in this case, endoscopists) to resist adopting these new technologies should not prevail. They can also help validate AI systems in real-world conditions by assessing their performance across a wide range of quality indicators. I want to congratulate the authors for their excellent work in a promising field." [Collapse]

Dimopoulou K, Spinou M, Ioannou A, Nakou E, Zormpas P, Tribonias G. Artificial intelligence in colonoscopy: Enhancing quality indicators for optimal patient outcomes. World J Gastroenterol 2025; 31(40): 111499

"This is very interesting paper.Higher serum gamma-glutamyl transpeptidase (γ-GTP) levels are associated with an increased risk of ..." [Read more]

"This is very interesting paper.Higher serum gamma-glutamyl transpeptidase (γ-GTP) levels are associated with an increased risk of pancreatic cystic neoplasms (PCNs) and their malignant progression. However, γ-GTP is not a specific diagnostic marker for these conditions. Its elevation is more indicative of general liver or biliary dysfunction and oxidative stress. Recent large-scale studies have found that people with higher baseline serum γ-GTP levels have a significantly increased risk of being diagnosed with PCNs later on. This suggests γ-GTP could potentially serve as a biomarker for identifying high-risk individuals for surveillance." [Collapse]

Lee MW, Park JM, Cho IR, Chung KH, Kim BS, Choi JH, Paik WH, Ryu JK, Han K, Lee SH. Serum gamma-glutamyl transferase level is associated with the risk of pancreatic cystic neoplasms: A nationwide retrospective cohort study. World J Gastroenterol 2025; 31(40): 110932

"Artificial intelligence has brought about a real revolution in various areas of human activities, including medical science. In recent ..." [Read more]

"Artificial intelligence has brought about a real revolution in various areas of human activities, including medical science. In recent years, AI has also emerged as a method to support the correct diagnosis and treatment of acute pancreatitis. Some elements of AI, such as machine learning, deep learning, natural language processing, and network pharmacology, seem to significantly facilitate diagnostic and therapeutic decisions in the treatment of patients with acute pancreatitis, through the analysis of clinical records, medical images, laboratory values, genomic data, and physiological signals in real time. AI functions as advanced decision support, enhancing clinical judgment with intelligence derived from diagnostic data, assessing risks to the patient from potential complications, and helping safely predict the disease. The authors also discuss future directions for AI development in the treatment of acute pancreatitis. As emphasized by the authors of this review, today's practical medicine often requires an interdisciplinary approach that integrates clinical experience, computational modeling, and ethical design. These largely theoretical data currently have limited application, especially in developing countries worldwide. For all health systems and in any country where AI is applied, its assistance should consist of improving decision-making through hybrid human-artificial intelligence models. The future looks excellent, although it causes concern and fear to the undersigned." [Collapse]

Zhang XY, Hu MD, Maimaitijiang D, Wang T, Wang L. Artificial intelligence in pancreatitis: A narrative review on advancing precision diagnosis, prognosis, and therapeutic strategies. World J Gastroenterol 2025; 31(39): 110971

"This review explores the bidirectional regulation between the gut microbiome and the immune system within the colorectal cancer (CRC) ..." [Read more]

"This review explores the bidirectional regulation between the gut microbiome and the immune system within the colorectal cancer (CRC) microenvironment. It highlights how microbial metabolites and immune signaling pathways influence tumor progression, immune evasion, and therapeutic response. Key mechanisms include TLR4 and NLRP3 activation, SCFA modulation, and PD-1 pathway interactions. The authors discuss emerging interventions such as engineered probiotics, FMT, and metabolic vaccines targeting the microbiota-immune axis. Overall, the study provides a comprehensive framework for developing personalized CRC therapies through microbiome modulation." [Collapse]

Liu XX, Yang B, Tang DX. Bidirectional regulation of the gut microbiome-immune axis in the immune microenvironment of colorectal cancer and targeted interventions. World J Gastrointest Oncol 2025; 17(10): 109503

"This retrospective two-center study investigates ultrasound features of primary intestinal lymphoma in children and their correlation ..." [Read more]

"This retrospective two-center study investigates ultrasound features of primary intestinal lymphoma in children and their correlation with prognosis. Twenty-eight pediatric cases were classified into focal segmental and extensive types based on sonographic findings. Extensive-type lymphoma was associated with significantly elevated LDH levels and poorer outcomes compared to the segmental type. Ultrasound classification and LDH levels showed strong prognostic relevance, while pathological type, age, and treatment modality did not. The study concludes that ultrasound is a valuable tool for diagnosis, classification, and prognosis prediction in pediatric intestinal lymphoma." [Collapse]

Huang SF, Yang F, Chen WJ, Zhang XH. Ultrasound features of primary intestinal lymphoma in children and their correlation with prognosis: A two-center experiment. World J Gastrointest Oncol 2025; 17(10): 109450

"This review highlights how lipid metabolic reprogramming drives colorectal cancer (CRC) progression, immune evasion, and therapy ..." [Read more]

"This review highlights how lipid metabolic reprogramming drives colorectal cancer (CRC) progression, immune evasion, and therapy resistance. It discusses key alterations in fatty acid synthesis, oxidation, and cholesterol metabolism, as well as the impact of high-fat diets and gut microbiota on the tumor microenvironment. The authors emphasize the role of lipid metabolism in shaping immunosuppressive dynamics and promoting cancer stemness and metastasis. By identifying actionable lipid-related pathways and enzymes, the review proposes novel therapeutic strategies, including combinations with immunotherapy. Overall, it offers a comprehensive and timely framework for advancing precision oncology in CRC." [Collapse]

Wang CD, Zhang BX, Song J. Lipid metabolic reprogramming in colorectal cancer: Insights to mechanisms and therapeutics. World J Gastrointest Oncol 2025; 17(10): 109398

"This multicenter retrospective study analyzed 189 colorectal cancer (CRC) patients admitted to intensive care units (ICUs) across ..." [Read more]

"This multicenter retrospective study analyzed 189 colorectal cancer (CRC) patients admitted to intensive care units (ICUs) across 37 cancer-specialized hospitals in China. The 90-day mortality rate was relatively low at 12.2%, with elective surgery and conventional oxygen therapy associated with better outcomes. Chemotherapy history and unplanned ICU transfers were linked to higher mortality, while severity scores like SOFA and APACHE II showed only moderate predictive value. This study is commendable for its large-scale, multicenter design and its focus on a clinically important yet underexplored patient population. By identifying key prognostic factors and highlighting the limitations of current scoring systems, the authors provide valuable insights that can inform ICU admission decisions and personalized care strategies for CRC patients." [Collapse]

Dong Q, Xia R, Xing XZ, Wang CS, Ma G, Wang HZ, Zhu B, Zhao JH, Zhou DM, Zhang L, Huang MG, Quan RX, Ye Y, Zhang GX, Jiang ZY, Huang B, Xu SL, Xiao Y, Zhang LL, Lin RY, Ma SL, Qiu YA, Zheng Z, Sun N, Xian LW, Li J, Zhang M, Guo ZJ, Tao Y, Zhou XZ, Chen W, Wang DX, Chi JY, Wang DH, Liu KZ. Intensive care unit outcomes and prognostic factors of colorectal cancer. World J Gastrointest Oncol 2025; 17(10): 108539

"This review highlights the link between ulcerative colitis (UC) and colitis-associated colorectal cancer (caCRC), emphasizing how ..." [Read more]

"This review highlights the link between ulcerative colitis (UC) and colitis-associated colorectal cancer (caCRC), emphasizing how chronic inflammation drives cancer development. It outlines key molecular pathways, immune responses, and microbiota changes involved in this process, and discusses current strategies for surveillance, chemoprevention, and surgical management. The authors advocate for precision medicine approaches to improve early detection and personalized care. The manuscript is commendable for its comprehensive integration of molecular and clinical insights. By combining updated surveillance guidelines with emerging biomarker research, it offers a forward-thinking framework that can guide more effective prevention and treatment strategies for caCRC in UC patients." [Collapse]

Catalano M, Mini E, Nobili S, Vascotto IA, Ravizza D, Amorosi A, Tonelli F, Roviello F, Roviello G, Nesi G. Ulcerative colitis and colorectal cancer: Pathogenic insights and precision strategies for prevention and treatment. World J Gastrointest Oncol 2025; 17(10): 108514

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist ..." [Read more]

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist (2016). 3 Results: case sharing of case presentation, findings and images. 4 Figures and tables: The author provides perfect images which is good quality and easily understandable plus interesting findings. 5 Biostatistics: Not applicable 6 References: Record the latest references which are important in this field and related to the scientific problems and case addressed in the study. 7 Language: The language in article correctly, clearly and concisely express the information. No grammatical and language mistakes. 8 Caveats or drawbacks: Not detected" [Collapse]

Wang WQ, Yang JP, Dong JW, Chen YB. Misdiagnosis of Crohn’s disease as appendicitis: A case report. World J Gastrointest Surg 2025; 17(9): 108348

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist ..." [Read more]

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist (2016). 3 Results: case sharing of case presentation, findings and images. 4 Figures and tables: The author provides good images which is good quality and easily understandable. Can be better figures intra-operative 5 Biostatistics: Not applicable 6 References: Record the latest references which are important in this field and related to the scientific problems and case addressed in the study. 7 Language: The language in article correctly, clearly and concisely express the information. No grammatical and language mistakes. 8 Caveats or drawbacks: Not detected" [Collapse]

Zhang J, Sun S, Zheng S, Ma YY, Chen G. Gastric adenomyoma in children: A case report. World J Gastrointest Surg 2025; 17(9): 107297

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist ..." [Read more]

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist (2016). 3 Results: case sharing of case presentation, findings and images. 4 Figures and tables: The author provides perfect images which is good quality and easily understandable. 5 Biostatistics: Not applicable 6 References: Record the latest references which are important in this field and related to the scientific problems and case addressed in the study. 7 Language: The language in article correctly, clearly and concisely express the information. No grammatical and language mistakes. 8 Caveats or drawbacks: Not detected" [Collapse]

Moon YJ, Lee SH. Inferior mesenteric arteriovenous fistula: Two case reports. World J Gastrointest Surg 2025; 17(9): 107139

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist ..." [Read more]

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist (2016). 3 Results: case sharing of case presentation, findings and images. 4 Figures and tables: The author provides good images which is good quality and easily understandable. need arrow in intra-operative image 5 Biostatistics: Not applicable 6 References: Record the latest references which are important in this field and related to the scientific problems and case addressed in the study. 7 Language: The language in article correctly, clearly and concisely express the information. No grammatical and language mistakes. 8 Caveats or drawbacks: Not detected" [Collapse]

Ahunayizhi A, Zhang XL, Chen Q, Wang H, Ding G, Akumuo S, Wang XX, Ruan XJ. Laparoscopic management of gallstones in a duplicate gallbladder with double cystic ducts: A case report. World J Gastrointest Surg 2025; 17(9): 110796

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist ..." [Read more]

"1 Ethics: Not applicable 2 Methods: Case report that the manuscript was prepared and revised according to the CARE Checklist (2016). 3 Results: case sharing of case presentation, findings and images. 4 Figures and tables: The author provides not medical photograph especially resected specimens photo. 5 Biostatistics: Not applicable 6 References: Record the latest references which are important in this field and related to the scientific problems and case addressed in the study. 7 Language: The language in article correctly, clearly and concisely express the information. No grammatical and language mistakes. 8 Caveats or drawbacks: Not detected" [Collapse]

Guo Q, Lu HY, Lyu H, Tian H, Zhao Q, Zheng YC. Complete appendiceal intussusception and appendiceal mucinous tumor: A case report and review of literature. World J Gastrointest Surg 2025; 17(9): 109320

"This is a very interesting analysis and "observational" association between BMI and ALF. This work supports the knowledge about obesity ..." [Read more]

"This is a very interesting analysis and "observational" association between BMI and ALF. This work supports the knowledge about obesity and the worldwide problem it represents as a health problem. With all due respect, this work lacks further analysis (hypothesis) on how this increased BMI contributes to organ failure. Further analysis should focus not only on organ (liver in this case) failure but on gastrointestinal symptomatology (effects) in general." [Collapse]

Krishnan A, Khan S, Gips J, Alqahtani SA, Vaidya D, Liu YS, Kim A, Su A, Gurakar A, Hamilton JP, Woreta TA. Body mass index and its association with clinical outcomes in acute liver failure. World J Clin Cases 2025; 13(30): 109212

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2264

Peer-reviewers: 34584

Manuscripts received today: 3

Manuscript reviews today: 5

Unhandled manuscripts today: 155

Active peer-reviewers today: 2306

Reviewer acceptance today: 10

Reviewer refusals today: 10

Total accepted manuscripts: 38504

Total rejected manuscripts: 43636

Total peer-reviewers: 4484320

Total submissions: 36494