Baishideng Publishing Group

Hua HW, Wu J. Transverse incision with longitudinal ligation procedure: Innovation, pitfalls, and clinical perspectives. World J Gastroenterol 2025; 31(48): 114738

"The peer-review and editorial process was conducted in a professional and constructive manner. The reviewers provided relevant and ..." [Read more]

"The peer-review and editorial process was conducted in a professional and constructive manner. The reviewers provided relevant and well-founded comments that helped improve the clarity of the manuscript, refine the methodological description and strengthen the interpretation of the results. We appreciate the editorial handling and the opportunity to improve the work prior to publication. " [Collapse]

Stanciu BI, Iojiban M, Morariu-Barb A, Caraiani C, Procopet B, Stefanescu H, Lupsor-Platon M. Hepatic enhancement and signal intensity analysis on magnetic resonance imaging as prognostic biomarkers in advanced chronic liver disease. World J Hepatol 2025; 17(12): 111418

"We are highly satisfied with the rigorous and constructive peer review process. The reviewers' detailed, insightful feedback ..." [Read more]

"We are highly satisfied with the rigorous and constructive peer review process. The reviewers' detailed, insightful feedback substantially improved our manuscript's scientific quality, clarity, and overall impact. We sincerely appreciate the editors' exceptional professional guidance, patience, and efficient coordination throughout the entire process. Their dedication was invaluable to us. We also thank the editorial staff for their thorough and timely support, which greatly facilitated a very smooth and successful publication. " [Collapse]

Fei ZH, Duan XF, Feng LH, Wang ZN, Chen YS, Sun ZW. Clinical study on the efficacy of laparoscopic hepatectomy via the retroperitoneal approach for treating liver tumors. World J Hepatol 2025; 17(12): 110764

"I am fully satisfied with the entire editorial and peer-review process, which was conducted with a high level of professionalism, ..." [Read more]

"I am fully satisfied with the entire editorial and peer-review process, which was conducted with a high level of professionalism, transparency, and efficiency. The reviewers’ comments were constructive and valuable, contributing to the improvement of the manuscript. I also appreciated the clear communication and timely handling of each stage of the process. Overall, I believe this journal represents an important platform for the dissemination of high-quality knowledge in psychiatry and across related professional disciplines. " [Collapse]

Anastasi G. Inflammation and suicide risk in adolescents with self-injury: Expanding the role of mental health nursing. World J Psychiatry 2026; 16(1): 113965

"he authors are very satisfied with the journal’s review speed and the overall editorial process. The manuscript was handled ..." [Read more]

"he authors are very satisfied with the journal’s review speed and the overall editorial process. The manuscript was handled efficiently, and each stage of the peer-review process was clearly structured and transparent. The reviewers’ comments were constructive and helpful, and communication with the editorial office was timely and professional. Overall, the submission and review experience was smooth, fair, and highly satisfactory. " [Collapse]

Zhang FF, Guo R, Chen SL, Yang W, Liang XL, Ma MF. Network perspective on rumination and non-suicidal self-injury among adolescents with depressive disorders. World J Psychiatry 2026; 16(1): 113130

"From submission to online publication, this manuscript underwent a rigorous and systematic peer-review and revision process. The ..." [Read more]

"From submission to online publication, this manuscript underwent a rigorous and systematic peer-review and revision process. The editorial office communicated efficiently and clearly at each stage. The reviewers provided professional and constructive comments on study design and data analysis, which substantially improved the content and overall quality of the manuscript. A minor limitation was the relatively extended interval between acceptance and online publication. " [Collapse]

Zhao SX, Han T, Bi WZ, Fei LL, Han LL, Wang YL, Ping ZG, Wang CJ, Hao CF, Xin YJ. Emotion regulation habits and emotional states of college students during lockdown: A cross-sectional survey. World J Psychiatry 2026; 16(1): 111778

"I am very satisfied with the review process of this magazine，and I think the peer review report for my manuscript is fair and ..." [Read more]

"I am very satisfied with the review process of this magazine，and I think the peer review report for my manuscript is fair and objective. I am satisfied with the editing and publishing rules and norms. I am satisfied with the published articles processes.I think the peer review report is help to my manuscript. " [Collapse]

Liu XF, Wu YH, Huang GX, Yu B, Xu HJ, Qiu MH, Kang L. Trajectory and influencing factors of changes in anxiety and depression in elderly patients after lumbar interbody fusion. World J Psychiatry 2026; 16(1): 112787

"it is with great pleasure, admiration and respect, that I salute you for your tremendously thorough evaluation and extensive oversight. ..." [Read more]

"it is with great pleasure, admiration and respect, that I salute you for your tremendously thorough evaluation and extensive oversight. You have a superior submission system to all other journals. It goes without saying that the process is a reflection of the journal and publisher's integrity and pursuit of excellence. It is both transparent and clear and I wish you the best of luck. " [Collapse]

Salem N, Moursel AH, Zahweh A, Shhadi D, Saad F, Reda M, Mghames M, Roumieh R, Tfaily R, Ramadan SM, Bou Dargham B, Rajab O, Akel F. Preoperative anxiety among patients and its correlation with their personality type and pain: A cross-sectional study. World J Psychiatry 2026; 16(1): 112129

"I am satisfied with my submission experience with the World Journal of Psychiatry. The editorial process was clearly structured, and ..." [Read more]

"I am satisfied with my submission experience with the World Journal of Psychiatry. The editorial process was clearly structured, and communication from the editorial office was consistent and appropriate. The peer review comments were substantive, methodologically informed, and focused on improving the scientific clarity and interpretability of the manuscript. Overall, the review process reflected a serious commitment to academic rigor and editorial responsibility. " [Collapse]

Yeh ST, Li MY, Chen YC. Mental and physical health outcomes among intimate partner violence survivors in Taiwan: A nationwide registry-based case control study. World J Psychiatry 2026; 16(1): 112745

"Journal demonstrates established credibility through its inclusion in recognized international indexing databases, implementation ..." [Read more]

"Journal demonstrates established credibility through its inclusion in recognized international indexing databases, implementation of a structured and transparent peer-review process, affiliation with a reputable academic publisher, clear adherence to publication ethics and research integrity standards, presence of an experienced and verifiable editorial board and alignment of published content with the journal’s stated scientific scope, collectively supporting its standing as a legitimate and scholarly publication venue. " [Collapse]

Shahid Y, Butt AS, Jamali I, Ismail FW. Rising incidence of acute hepatitis A among adults and clinical characteristics in a tertiary care center of Pakistan. World J Virol 2025; 14(1): 97482

"Journal demonstrates established credibility through its inclusion in recognized international indexing databases, implementation ..." [Read more]

Majeed AA, Butt AS. Gut microbiota: An overlooked target in dyslipidemia management. World J Gastroenterol 2025; 31(48): 113178

"Journal demonstrates established credibility through its inclusion in recognized international indexing databases, implementation ..." [Read more]

Majeed AA, Sarfraz M, Butt AS. Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies. World J Virol 2025; 14(4): 112590

"We are pleased to share our positive experience regarding the submission and publication of our manuscript entitled “Protective effect ..." [Read more]

"We are pleased to share our positive experience regarding the submission and publication of our manuscript entitled “Protective effect of Guanxinning on antipsychotic-induced cardiac impairment in long-term hospitalized psychiatric patients” in the World Journal of Psychiatry(Manuscript NO. 111840). The editorial and production process was handled with high efficiency and professionalism. From initial submission to final publication, communication with the editorial office was clear, timely, and constructive. The peer review was thorough and insightful, providing valuable suggestions that significantly strengthened the manuscript. The language editing and formatting support further enhanced the clarity and presentation of our work. We also appreciate the journal’s commitment to transparency, as reflected in the public availability of peer review reports, author responses, and CrossCheck documentation, which adds to the credibility of the published research. The open-access policy ensures that our findings can be widely disseminated, supporting further scientific and clinical discussion in the field. Overall, we are satisfied with the collaborative and rigorous publishing process and would gladly consider this journal for future submissions. We encourage other researchers in psychiatry and related disciplines to submit their work to the World Journal of Psychiatry.+ " [Collapse]

Luo FG, Xing HY, Wang JJ, Wu WY, Fang KJ, Song HD, Yan J. Protective effect of Guanxinning on antipsychotic-induced cardiac impairment in long-term hospitalized psychiatric patients. World J Psychiatry 2026; 16(1): 111840

"Questionnaires and other methods have traditionally been used to detect dementia early. In recent years, methods such as measuring ..." [Read more]

"Questionnaires and other methods have traditionally been used to detect dementia early. In recent years, methods such as measuring trace blood components such as tau protein and imaging diagnostics of amyloid accumulation in the brain have been put to practical use, but these are expensive and have not yet been put to clinical use. I believe that early decline in cognitive function can be measured by clinically measuring the multitasking function of parallel distributed processing in the brain's information processing. I believe that the theory in this paper will be useful in creating an inexpensive and practical method. I am grateful for the thorough peer review and publication. " [Collapse]

Nagamine T. Unlocking the silent signals: Motor kinematics as a new frontier in early detection of mild cognitive impairment. World J Psychiatry 2026; 16(1): 112073

"The World Journal of Clinical Cases demonstrated commendable professionalism and efficiency in handling this complex case report. ..." [Read more]

"The World Journal of Clinical Cases demonstrated commendable professionalism and efficiency in handling this complex case report. The editorial process ensured thorough peer review and facilitated clear presentation of the diagnostic challenges and clinical insights. Timely communication and attention to detail enhanced the manuscript’s clarity and clinical impact, reflecting well on the journal’s commitment to quality and relevance. " [Collapse]

Taha R, Elsayed G, Mohamed L, Gadour E. Beyond biliary causes, fish bone perforation as a rare etiology of recurrent fever in a post-Whipple patient: A case report. World J Clin Cases 2025; 13(36): 114956

"The peer review process was overall efficient and smooth, and the editorial team was very helpful and constructive. The comments ..." [Read more]

"The peer review process was overall efficient and smooth, and the editorial team was very helpful and constructive. The comments provided by the reviewers and the editor enhanced the quality of the paper. I believe the ranking in term of the journal's quartile and the impact factor will be increasing in the near future especially with such professional follow-up. My team and I would like to thank the reviewers and the editor and editorial team for all the efforts. " [Collapse]

Youssef J, Yehya A, Salhab Z, Bitar R, Ghamlouche F, Bahmad HF, Abou-Kheir W. Liquid biopsy in genitourinary cancers: Diagnostic and prognostic implications. World J Clin Oncol 2025; 16(12): 113578

"This submission system is well-designed, making it convenient for authors to submit manuscripts, and the instructions are very clear. ..." [Read more]

"This submission system is well-designed, making it convenient for authors to submit manuscripts, and the instructions are very clear. The reviewers' comments are highly professional and significantly improve the quality of the article. Moreover, the review feedback is returned in a timely manner. I have no further comments—this has been a pleasant submission experience. " [Collapse]

Qiao XY, Shen XJ, Lv YH, Chen RB, Weng J, Xu GL, Wen G, Bai KH. Endoscopic submucosal dissection and hybrid endoscopic submucosal dissection for stage 1 rectal neuroendocrine tumors. World J Clin Oncol 2025; 16(12): 112871

"Chronic hepatitis B virus (HBV) infection acquired in childhood frequently presents with mild or nonspecific symptoms, yet a distinct ..." [Read more]

"Chronic hepatitis B virus (HBV) infection acquired in childhood frequently presents with mild or nonspecific symptoms, yet a distinct subset of pediatric patients develops rapid progression to cirrhosis before adulthood. In this study, we investigated the clinical characteristics of pediatric liver cirrhosis, the response to different antiviral therapies, and the pathological characteristics of children at different fibrosis stages. We also analyzed the clinical differences between pediatric liver cirrhosis and pediatric chronic hepatitis B (CHB), as well as the distinctions between pediatric and adult cirrhosis. Pediatric cirrhosis is mostly detected via physical examination with rare symptoms, whereas adults typically present with jaundice, hematochezia, and fatigue. Pediatric cirrhosis has a better prognosis than adult cases, with higher hepatitis B surface antigen seroclearance rates and potential rapid reversal in some instances, while adult cirrhosis generally carries a poor prognosis. Pediatric cirrhosis progresses more rapidly (even occurring in children < 3 years old), whereas adult cases follow a slower clinical course. Children with cirrhosis often have a history of liver dysfunction and frequently experience disease recurrence due to self-discontinuation of hepatoprotective/antiviral/traditional Chinese medicine treatments. " [Collapse]

Zhao BK, Li Y, Jiang YY, Li ML, Jiang Y, Zhu L, Guo CN, Liu SH, Chen L, Jiang LN, Niu JQ, Zhao JM. Clinical, pathological characteristics and long-term outcomes of hepatitis B virus related cirrhosis in pediatric observational study. World J Gastroenterol 2025; 31(48): 114049

"I am not satisfied with making the origin of the paper by the country of origin of the corresponding author. For example, if the paper ..." [Read more]

"I am not satisfied with making the origin of the paper by the country of origin of the corresponding author. For example, if the paper was a systematic review in Africa, however, the corresponding author is from UK, the origin of the paper is indicated UK. This is not appropriate in my opinion. The section should include continent or region of origin because systematic reviews is a collection of manuscripts from greater region and not necessarily a particular country. If we are to follow STROBE reporting, it is expected the study design written in the title. However, with the word limit of 18 for the title, most of the time we cannot include study design. This should be looked at to increase title’s word limit. Reference check tool is helpful; however, it is an AI based tool. Editors should take time to check why particular reference was flagged. Often time it was cited because of the method used to analyze data but not necessarily the content of the paper. Citing method paper is ok, it should not be a problem to delay the process. Similarly, to author prior own work. There is no harm citing own prior work. " [Collapse]

El-Imam IA, Peter TA, Fussi HF, Ally ZM, Bakari HM, Mbwana MS, Chenya UK, Mpimo BK, Ally HM, Ramadhani HO. Human immunodeficiency virus recency testing coverage and partner-notification-services among people-living with human immunodeficiency virus in low- and middle-income countries. World J Virol 2025; 14(4): 111810

"Omental torsion (OT) is a rare but significant cause of acute abdomen, frequently masquerading as more common conditions like acute ..." [Read more]

"Omental torsion (OT) is a rare but significant cause of acute abdomen, frequently masquerading as more common conditions like acute appendicitis. Preoperative diagnosis remains challenging due to nonspecific clinical presentations. This case report aims to reinforce the critical role of modern imaging combined with minimally invasive surgery in achieving timely diagnosis and effective management of this elusive condition. We provide a complete diagnostic circuit—from characteristic CT findings to intraoperative gross pathology and final histopathological confirmation (showing hemorrhage, necrosis, and vascular embolism). This comprehensive documentation deepens the understanding of the disease's progression from vascular torsion to tissue infarction. " [Collapse]

Li YL, Fan JX, Yang Y, Yao MQ, Jiang YP. Omental torsion diagnosed by abdominal contrast-enhanced computed tomography: A case report. World J Radiol 2025; 17(12): 114398

20375 items Read more >>

Article Quality Tracking-Peer-Review

"I would like to commend the authors for an exceptionally comprehensive and timely review on strategies to optimize mesenchymal stem ..." [Read more]

"I would like to commend the authors for an exceptionally comprehensive and timely review on strategies to optimize mesenchymal stem cell (MSC) therapy for tendon-bone healing. I found the sections on MSC-derived extracellular vesicles (EVs)/exosomes particularly insightful. The manuscript effectively highlights the advantages of EV-based, cell-free therapies, including lower immunogenicity, reduced tumorigenic risk, and the ability to mediate paracrine effects similar to parent MSCs, positioning them as a promising modality for tendon-bone regeneration. The discussion of strategies to enhance EV efficacy, such as preconditioning of parent MSCs (hypoxia, LIPUS, magnetic stimulation, and pharmacological agents) and engineering delivery platforms (endogenous/exogenous loading, surface modifications for targeted delivery), is highly relevant for translational applications. I especially appreciated the emphasis on exosome-mediated modulation of macrophage polarization, promotion of angiogenesis, and enhancement of osteogenic and chondrogenic differentiation, which highlights their mechanistic versatility. While the manuscript provides excellent mechanistic insight and preclinical evidence, a brief discussion on challenges in EV translation—such as scalable production, stability, standardization of dosing, and regulatory considerations—could further strengthen the practical relevance. Nonetheless, this focused review of MSC-derived EVs significantly contributes to the field by showcasing both the potential and current hurdles of cell-free therapies for tendon-bone healing." [Collapse]

Li H, Li ZP, Zhu MT, Lan CH, Wang YX, Liao P, Chen Z, Wang P, Sun JK, Shi Z, Lu PY, Lou C, Xu GH. Optimizing mesenchymal stem cell therapy for tendon-bone healing: Multifaceted approaches and future directions. World J Stem Cells 2025; 17(12): 114076

"The ethical approval provided by the author meet the requirements. This report provided a rare case report, with educational ..." [Read more]

"The ethical approval provided by the author meet the requirements. This report provided a rare case report, with educational significance. Of “It is a safe and reliable approach for OT treatment, which offers the advantages of minimal trauma, mild postoperative pain, and rapid recovery for stylistic precision”. It’s not adequate in this section. Of “Abdominal contrast-enhanced CT plays a crucial role in diagnosing OT, and laparoscopic surgery is a safe and effective diagnostic and therapeutic approach” in the conclusion. It’s not adequate to address “and laparoscopic surgery is a safe and effective diagnostic and therapeutic approach” in the “Conclusion”. Structure of relative description was not adequate. Discussion needs not involve much about other aspects of omental torsion other than imaging diagnosis, it should focus on imaging diagnosis and differential diagnosis, especially contrast-enhanced CT and contrast-enhanced ultrasound. Compared to CT, contrast-enhanced CT has higher sensitivity and specificity in the visualization of the omental vascular running and contrast perfusion, and has better ability to determine whether there is ischemia and associate secondary change. “whirlpool sign” is unique for the diagnosis of omental torsion. Duplex ultrasound can find “whirlpool sign” and loss of color signal of vascualrity in some cases of omental torsion. It should be addressed that color Doppler flow imaging is usually not able to detect blood vessels in the great omentum. Contrast-enhanced ultrasound can find defect of vascular perfusion in the region of the great omentum with necrosis, while there was discussion on this technique. It should be addressed that “whirlpool sign” can only be detected in part cases of omental torsion. Ovary torsion has “whirlpool sign” and abdominal emergency, and differential diagnosis is required. The report was written in English awkwardly, not meeting native English and standardized professional expression. Of Figure 1. There were no arrows to indicate “whirlpool sign” of omental torsion. Of “(hematoxylin and eosin, × 50)” in Figure 4. “× 50” does not follow routine practice, and it may be mistaken. " [Collapse]

Li YL, Fan JX, Yang Y, Yao MQ, Jiang YP. Omental torsion diagnosed by abdominal contrast-enhanced computed tomography: A case report. World J Radiol 2025; 17(12): 114398

"This is very interesting paper about the relationship between IBD and Alzheimer’s. Recent studies suggest that patients with IBD ( ..." [Read more]

"This is very interesting paper about the relationship between IBD and Alzheimer’s. Recent studies suggest that patients with IBD ( UC and chronic ) have a significantly higher about 2.5 times risk of developing dementia,including Alzheimer’s disease and are diagnosed at a younger age. This association may be due to the intestinal inflammation caused by IBD, disruption of intestinal flora and dysfunction of the gut-brain axis sharing a common pathway with the underlying mechanisms of Alzheimer’s disease (such as amyloid beta accumulation),and it is possible that improving the intestinal environment may lead to the prevention of dementia." [Collapse]

Durairajan SSK, Singh AK, Sulaiman SM, Patnaik S, Krishnamoorthi S, Iyaswamy A, Vellingiri B, Yang CB, Williams LL. Molecular links between inflammatory bowel disease and Alzheimer’s disease through immune signaling and inflammatory pathways. World J Gastroenterol 2025; 31(48): 111301

"Bouveret syndrome is a rare form of gallstone ileus, presenting as gastric outlet obstruction due to a large gallstone that has ..." [Read more]

"Bouveret syndrome is a rare form of gallstone ileus, presenting as gastric outlet obstruction due to a large gallstone that has migrated through a biliogastric or bilioduodenal fistula.This manuscript is a well-written and presented rarely case report.Bouveret Syndrome primarily affects elderly patients. The authors point out that it may also occur in young individuals. I think that this manuscript is worth to publication." [Collapse]

Hu YC, Chen XY, Cao MK, Fan Z. Bouveret syndrome in a young patient: A case report and review of literature. World J Gastrointest Surg 2025; 17(12): 113532

"This study clearly highlights the importance and contribution of AI in the diagnosis of rectal neuroendocrine tumors in daily clinical ..." [Read more]

"This study clearly highlights the importance and contribution of AI in the diagnosis of rectal neuroendocrine tumors in daily clinical practice. It is known that rectal endocrine tumors present significant diagnostic difficulties because they are often considered as hyperplastic polyps and are either not removed and therefore not subjected to histological evaluation, or are removed as normal polyps. The consequence is that diagnosis is delayed or requires subsequent complementary imaging and/or endoscopic examination. The authors developed an image analysis and detection model for rectal neuroendocrine tumors using the YOLOv7 algorithm. This algorithm demonstrated significant diagnostic accuracy, exceeding that of most endoscopes with which it was compared. It has been repeatedly emphasized that AI is expected to revolutionize the diagnosis of many gastrointestinal diseases, including rectal endocrine tumors. We experience this to a large extent in daily clinical practice. However, it should be emphasized that the effectiveness of this system in detecting neuroendocrine rectal tumors should be investigated and evaluated in future large, multicenter studies." [Collapse]

Liu K, Wang ZY, Yi LZ, Li F, He SH, Zhang XG, Lai CX, Li ZJ, Qiu L, Zhang RY, Wu W, Lin Y, Yang H, Liu GM, Guan QS, Zhao ZF, Cheng LM, Dai J, Bai Y, Xie F, Zhang MN, Chen SZ, Zhong XF. Artificial intelligence-assisted diagnosis of rectal neuroendocrine tumors during white-light endoscopy. World J Gastroenterol 2025; 31(48): 112683

"1. The authors have projected the cardiotoxicity as a sequel of chemotherapy relevant to LMIC in perspective, documenting the follow ..." [Read more]

"1. The authors have projected the cardiotoxicity as a sequel of chemotherapy relevant to LMIC in perspective, documenting the follow up timings 2. The importance of the follow up and its necessity is also well brought out in the light of current literature 3. The relevance of cardiotoxicity lies in the drug / regime and the dosage. Especially if the patient was administered more than the expected maximal dosage. This can be included for better understanding. " [Collapse]

Ali W, Mehmood A, Surani S. Chemotherapy-related cardiotoxicity: Bridging the gap between evidence and practice. World J Clin Cases 2025; 13(36): 114228

"1. The difference of a squamous cell ca in a viscera, in comparison to that in the superficial skin site can be brought out in terms ..." [Read more]

"1. The difference of a squamous cell ca in a viscera, in comparison to that in the superficial skin site can be brought out in terms of presentation, prognosis / management / tumor behaviour, etc 2. When to suspect a similar lesion can be highlighted for the benefit of readers 3. The conclusion section can avoid summary of the manuscript, rather can include a crisp take home message on the index case." [Collapse]

Li QQ, Wei J, Fang LY, Zhou JL, Zhao HF. Primary ileal squamous cell carcinoma: A case report and review of literature. World J Clin Cases 2025; 13(36): 111835

"The article entitled Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies is well ..." [Read more]

"The article entitled Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies is well written article but some comments to be considered: - Most of the studies included in the review article depend on seroprevalence of the disease that is mean it depend on detection of antibodies which of course of low speceficity as diagnosis of HAV infection must depend on isolation of the virus by real time PCR especially in endemic areas to avoid false positive results. - There is some redunduncy and reptition of the data (e.g Endemicity in the era of vaccination and improving living standards -- Changing epidemiology of hepatitis A " [Collapse]

Majeed AA, Sarfraz M, Butt AS. Evolving trends in hepatitis A epidemiology: Shifting patterns, emerging risks, and future strategies. World J Virol 2025; 14(4): 112590

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Huang K. Influence of obesity on the patient’s recovery after laparoscopic surgery. World J Clin Cases 2025; 13(36): 115269

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Li QQ, Wei J, Fang LY, Zhou JL, Zhao HF. Primary ileal squamous cell carcinoma: A case report and review of literature. World J Clin Cases 2025; 13(36): 111835

"In this study, the authors describe a patient with severe ulcerative colitis resistant to treatment and comorbid health problems who ..." [Read more]

"In this study, the authors describe a patient with severe ulcerative colitis resistant to treatment and comorbid health problems who responded favorably and without side effects to the combined treatment of an α4β7 integrin antagonist (vedolizumab) and an interleukin 23p19 inhibitor (mirikizumab). This case reinforces the view, expressed over the last few years, of the need to combine two biological agents in treatment-resistant inflammatory bowel disease and in treatment-resistant patients with extraintestinal manifestations. Personally, I believe we will be led to adopt the above recommendation in the near future. What remains is the approval and adoption of this recommendation by the pharmaceutical companies manufacturing biological agents, so they can conduct extensive, multicenter studies and avoid being limited to descriptions of individual cases or series from specialized centers with very small patient numbers." [Collapse]

Guimarães AC, Ferreiro-Iglesias R, Calviño-Suarez C, Baston-Rey I, Barreiro-de Acosta M. Dual biologic therapy in patient with refractory ulcerative colitis and comorbidities: A case report. World J Gastroenterol 2025; 31(47): 113381

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? Not applicable. 2 Methods: Is the ..." [Read more]

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? Not applicable. 2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)? Not applicable. 3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated? Not applicable. 4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated? Yes. 5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data? Not applicable. 6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references? Yes. 7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes? Yes. 8 Caveats or drawbacks: What are the caveats or drawbacks for the results? They didn't provide many new ideas." [Collapse]

"These findings illuminate the pivotal role of YY1 in driving the progression of Helicobacter pylori-induced gastric carcinogenesis ..." [Read more]

"These findings illuminate the pivotal role of YY1 in driving the progression of Helicobacter pylori-induced gastric carcinogenesis through the activation of epithelial-mesenchymal transition (EMT). From a molecular vantage point, this study stands as a compelling testament to rigorous scientific inquiry, underpinned by a wealth of robust experimental evidence that substantiates its central claims. Here I only offer a suggestion and reference. In fact, cancer is a complex pathological ecosystem rather than a simple genetic disease. However, the current mainstream research perspective is greatly influenced by the "somatic mutation" theory, often believing that genes and molecules are the ultimate essence of cancer. However, such a linear reductionist view has not brought about fundamental improvements in prognosis in clinical practice, such as in targeted therapy. I believe that in the post-genomic era, we should think more about the occurrence and development of cancer from the perspectives of ecology and evolution rather than being confined to the molecular level. As I pointed out in the "Rethinking Cancer" column for the 110th anniversary of the Chinese Medical Association (https://pubmed.ncbi.nlm.nih.gov/40443342/), the key to understanding such a complex systemic disease as tumors does not lie in the relentless pursuit of genes and molecules. It can be said that the role and function (promoting or inhibiting cancer, driver, passenger or neutral) of a single gene mutation in cancer cells depend on the environment and ecological niche in which they are located. By the way, I kindly recommend the authors and your team explore the book "Rethinking Cancer" (Strauss B. et al., 2021), which is also available in Chinese version (2024, Tsinghua University Press). This book might offer a refreshing and insightful perspective on human cancers, which could help guide future research and practice and better assist in improving patient prognosis." [Collapse]

Chen JW, Ouyang JJ, Wang ZH, Ma DM, Zhang Z, Teng Q, Yu G, Li XY. Yin Yang 1 activates JAK-STAT3-mediated epithelial-mesenchymal transition in Helicobacter pylori-induced gastric cancer progression. World J Clin Oncol 2025; 16(12): 112626

"This is very interesting paper. The authors state that the Bismuth-Corlett classification, hypokalemia, and AST levels were identified ..." [Read more]

"This is very interesting paper. The authors state that the Bismuth-Corlett classification, hypokalemia, and AST levels were identified as independent risk factors for PBI following ERCP drainage. The Bismuth-Corlett classification and AST levels can be understood as risk factors for drainage infection after ERCP, but please explain why hypokalemia is a risk factor. Please state in numbers how much hypokalemia is and what the AST level is." [Collapse]

Wang YF, Han K, An N, Sun YN, Gao F, Sun Y, Zhang D, Zhao ZF, Guo Q, Gu JN, Yang Z. Risk prediction of biliary infection after endoscopic drainage for malignant perihilar biliary obstruction: A 10-year multicenter retrospective study. World J Gastroenterol 2025; 31(47): 113156

"The study is particularly strong in its development of a multimodal fusion model that integrates clinical data, radiomics, and habitat ..." [Read more]

"The study is particularly strong in its development of a multimodal fusion model that integrates clinical data, radiomics, and habitat imaging to achieve markedly superior performance in predicting early recurrence of hepatocellular carcinoma, outperforming traditional single‑modality models in both accuracy and clinical net benefit. It also excels by incorporating SHAP‑based interpretability to clarify how specific imaging and clinical features contribute to predictions, and by validating meaningful correlations between selected radiomic/habitat features and key pathological markers such as MVI, Ki‑67, and GPC‑3, thereby enhancing biological plausibility and clinical relevance." [Collapse]

Huang LH, Fang YJ, Zheng XJ, Huang C, Li CL, Yu B, Huang MJ, Qin SJ, Huang DY, Lu DW. Application of multimodal fusion technology in early recurrence prediction and pathological analysis of hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(12): 114037

"The study excels by integrating radiomics and body composition metrics from both pretreatment and follow‑up T12‑level CT scans, ..." [Read more]

"The study excels by integrating radiomics and body composition metrics from both pretreatment and follow‑up T12‑level CT scans, demonstrating that combining these imaging biomarkers with clinical data markedly improves the accuracy of survival prediction in esophageal cancer. It also stands out for using automated segmentation tools to eliminate manual variability, rigorously comparing multiple machine‑learning models, and showing that follow‑up imaging adds substantial prognostic value. Overall, the research provides a practical, non‑invasive, and clinically applicable framework that enhances personalized risk stratification when traditional L3‑level imaging is unavailable." [Collapse]

Liu MC, Cheng YY, Lin SC, Lin CH, Chuang CY, Chen WH, Liao CH, Hsieh CH, Hsieh MF, Liu YJ. Machine learning survival prediction in esophageal cancer using radiomics and body composition from pretreatment and follow-up T12-level computed tomography. World J Gastrointest Oncol 2025; 17(12): 112873

"The study demonstrates several strengths, including the safe and smooth execution of cryoablation without perioperative deaths, the ..." [Read more]

"The study demonstrates several strengths, including the safe and smooth execution of cryoablation without perioperative deaths, the clear improvement in immune function and pain reduction following treatment, and the meaningful clinical benefits such as tumor shrinkage and prolonged overall survival compared with chemotherapy alone; together, these findings highlight cryoablation as an effective, minimally invasive option that enhances quality of life and offers a promising therapeutic alternative for patients with locally advanced pancreatic cancer." [Collapse]

Kang LM, He XL, Lang L, Wang AY, Wang X, Liu YH, Zhao YH, Xu L, Yu FK, Zhang FW. Safety and efficacy of cryoablation in treating locally advanced pancreatic cancer. World J Gastrointest Oncol 2025; 17(12): 113387

"The study evaluated a WeChat‑based bowel preparation monitoring system for outpatients undergoing colonoscopy and found that, compared ..." [Read more]

"The study evaluated a WeChat‑based bowel preparation monitoring system for outpatients undergoing colonoscopy and found that, compared with traditional oral and written education, the digital system significantly reduced patients’ anxiety and depression, improved bowel cleanliness, enhanced key colonoscopy quality indicators such as cecal intubation rate and polyp detection rate, increased patient compliance with dietary and medication instructions, and lowered the incidence of adverse reactions, demonstrating that real‑time, interactive, and personalized guidance can meaningfully improve the overall effectiveness and safety of colonoscopy preparation." [Collapse]

Xi MJ, Gong YP, Tao J, Li F, Xu MY, Gu X, Bao H, Jiang S, Xu B. Exploring the improvement effect of intestinal network monitoring system on intestinal preparation quality of colonoscopy. World J Gastrointest Oncol 2025; 17(12): 111101

"The article provides a rigorous and comprehensive meta‑analysis evaluating the prognostic significance of cancer‑associated fibroblasts ..." [Read more]

"The article provides a rigorous and comprehensive meta‑analysis evaluating the prognostic significance of cancer‑associated fibroblasts in liver cancer using real‑world clinical data. It strengthens its conclusions through well‑structured subgroup analyses across different CAF markers and cancer types, offering a more nuanced understanding of their prognostic value. The study also adheres to PRISMA guidelines and includes only high‑quality research, enhancing the reliability and credibility of its findings." [Collapse]

Wei YH, Jiang WJ, Wang SQ, Cai YL, Ma XL. Cancer-associated fibroblasts, clinicopathological characteristics and prognosis of liver cancer: A systematic review and meta-analysis based on real-world research. World J Gastrointest Oncol 2025; 17(12): 110395

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2264

Peer-reviewers: 35405

Manuscripts received today: 10

Manuscript reviews today: 22

Unhandled manuscripts today: 199

Active peer-reviewers today: 1528

Reviewer acceptance today: 49

Reviewer refusals today: 48

Total accepted manuscripts: 39320

Total rejected manuscripts: 44182

Total peer-reviewers: 4615291

Total submissions: 37400