Baishideng Publishing Group

Triantafyllou G, Papadopoulos-Manolarakis P, Arkoudis NA, Moschovaki-Zeiger O, Velonakis G, Piagkou M. Magnetic resonance imaging-based classification of trigeminal nerve-superior cerebellar artery relationships. World J Radiol 2025; 17(12): 116453

"It is always a pleasure to work together with the BPG, and I am excited for further publications in the future. Relative to other ..." [Read more]

"It is always a pleasure to work together with the BPG, and I am excited for further publications in the future. Relative to other journals, the process from submission to publication is fast most of the time. Peer review reports are usually helpful and constructive. Keep up the excellent work. " [Collapse]

Arkoudis NA, Siderakis M, Tsetsou I, Efthymiou E, Triantafyllou G, Chalmoukis D, Karachaliou A, Papadopoulos A, Prountzos S, Moschovaki-Zeiger O, Gouliopoulos N, Papakonstantinou O, Filippiadis D, Velonakis G. Developmental venous anomalies and cerebral cavernous malformations: Partners in crime. World J Radiol 2025; 17(12): 114595

"The submission process went smoothly. I am grateful to the editor and the reviewers for their assistance. During the submission ..." [Read more]

"The submission process went smoothly. I am grateful to the editor and the reviewers for their assistance. During the submission process, through communication with the editor and the reviewers, I learned a lot of knowledge. I also gained a lot of insights into the writing of the article, the creation of tables and figures, etc. This will be of great help for future research. I hope there will be more cooperation in the future. " [Collapse]

Cai B, Qiao ML, Miao D, Liu GZ. Cardiac myxoma and its implications for cardioembolic stroke. World J Cardiol 2025; 17(12): 112396

"All comments and suggestions provided by the reviewers and the editorial team have been carefully considered. In response to their ..." [Read more]

"All comments and suggestions provided by the reviewers and the editorial team have been carefully considered. In response to their constructive feedback, we have revised the manuscript and made the necessary corrections and improvements. Particular attention has been given to the methodology, discussion, and overall clarity of presentation. We believe that this revision process has significantly enhanced the scientific contribution and quality of the paper. We sincerely thank the reviewers and editors for their valuable time and insightful comments. " [Collapse]

Öndeş B, Gökdere OG, Kanat BH. Effect of resected gastric volume on weight loss after sleeve gastrectomy: A retrospective clinical study. World J Gastrointest Surg 2025; 17(12): 113571

"We would like to share some constructive feedback regarding our experience with the editorial process. On this occasion, the process ..." [Read more]

"We would like to share some constructive feedback regarding our experience with the editorial process. On this occasion, the process was efficient and relatively fast, which we truly appreciate. However, in previous submissions we have experienced considerably longer response times, which can be challenging for authors, particularly when revisions are time-sensitive. Another aspect we have noticed, both in this journal and within the same editorial group, is that minor revision requests are sometimes communicated in multiple rounds. It might be helpful to consolidate all minor comments into a single revision round whenever possible, as this would streamline the process and reduce repeated back-and-forth communications. Finally, we observed that several formal and administrative requirements are requested during the review and revision stages. While we fully understand their importance, some of these requirements might be more efficiently requested after a manuscript has been formally accepted, rather than during the peer-review process. We share these comments in a constructive spirit, with the aim of contributing to an even more efficient and author-friendly editorial workflow. " [Collapse]

Ramos-Gregorio CO, Tremillo-Maldonado O, Silveira F, Schuch LF, Pereira-Prado V, Sicco E, Soto-Najera AC, GómezPalacio-Gastélum M, Isiordia-Espinoza M, Muñoz-Ibarra JJ, Toral-Rizo V, Bologna-Molina R. Multifocal epithelial hyperplasia: Clinical features, diagnosis and management challenges. World J Exp Med 2025; 15(4): 114368

"We appreciate the opportunity to submit our work to F6 Publishing. The process was overall easy to manage, but the submission page ..." [Read more]

"We appreciate the opportunity to submit our work to F6 Publishing. The process was overall easy to manage, but the submission page had a few glitches without well-explained error messages. We also waited several months from article acceptance to article publication. However, the peer review comments were valuable for improving our final manuscript. " [Collapse]

Hutchinson HJ, Gonzalez M, Feier D, Welch CE, Lucke-Wold B. Colorectal cancer metastasis to the brain: A scoping review of incidence, treatment, and outcomes. World J Gastrointest Pathophysiol 2025; 16(4): 110961

"As the corresponding author of this manuscript, I would like to express my high level of satisfaction with the entire submission and ..." [Read more]

"As the corresponding author of this manuscript, I would like to express my high level of satisfaction with the entire submission and publication process. The editorial team demonstrated rigor, efficiency, and professionalism throughout all stages of manuscript handling: The online submission system was user-friendly and well-structured, with timely updates on manuscript status, greatly facilitating progress tracking. The peer review process was not only reasonably timed but also provided detailed and constructive feedback. The reviewers offered valuable suggestions regarding study design, data interpretation, and academic expression, which substantially enhanced the scholarly quality and logical coherence of the paper. The editing and production quality was commendable, with professional language polishing, clear formatting of figures and tables, and final PDF and online versions that fully met academic publishing standards. The publication workflow was transparent and well-organized, with a reasonable timeframe from acceptance to online publication, aligning with the timeliness required for academic dissemination. The journal’s academic norms and ethical guidelines were clearly communicated, and the editorial office proactively provided relevant guidelines and conducted plagiarism checks, reflecting the journal’s strong commitment to academic integrity. Overall, the journal excels in academic services, publication quality, and author support, demonstrating a strong academic reputation and professional standards. I would gladly recommend this journal to my peers and look forward to future collaborations. " [Collapse]

Ma HY, Chen YW, Liu X, Zhang MM, Tan BB. Modified Pingwei Baohe decoction improves postoperative recovery in gastric cancer patients. World J Gastrointest Surg 2025; 17(12): 113364

"It has been such a pleasant experience submitting our work to your journal. The reviewers provided insightful suggestions that truly ..." [Read more]

"It has been such a pleasant experience submitting our work to your journal. The reviewers provided insightful suggestions that truly enhanced the quality of the manuscript. Your editorial team's dedication and efficiency are truly commendable. We are already looking forward to the opportunity of contributing to your esteemed journal again in the future. " [Collapse]

Gong L, Yu J, Lv ZB, Qin XZ, Li M, Guo W, Huang B, Tian YH. Reducing anastomotic complications with endoscopy in laparoscopic total gastrectomy. World J Gastrointest Surg 2025; 17(12): 114079

"We sincerely thank the reviewers for their insightful comments and the editor for effectively facilitating the review process. The ..." [Read more]

"We sincerely thank the reviewers for their insightful comments and the editor for effectively facilitating the review process. The constructive feedback significantly enhanced the quality of our manuscript. While we appreciate the academic rigor, we believe the overall publication period could be shorter to ensure more timely dissemination. We are grateful for the editorial team's support and the professional handling of our submission throughout this period. " [Collapse]

Katsaros I, Papadakos SP, Despotidis M, Koutsoumpas A, Schizas D. Endoscopic vacuum-assisted closure as a first-line treatment for post-esophagectomy anastomotic leaks: A paradigm shift in management. World J Gastrointest Surg 2025; 17(12): 113305

"I am happy to provide the author’s comments for our submission to World Journal of Gastrointestinal Pathophysiology. The process of ..." [Read more]

"I am happy to provide the author’s comments for our submission to World Journal of Gastrointestinal Pathophysiology. The process of submission is efficient. The authors feel well supported. The peer review was very helpful. Overall, the experience from submission to publication was good. I am thankful to the journal editing and production team. " [Collapse]

Dutta AK, Vishruth S, Kovi SL, Dadhich P, Polavarapu J, Abraham D. Gut microbiota as a potential predictor of therapeutic response in adults with Crohn’s disease: A systematic review. World J Gastrointest Pathophysiol 2025; 16(4): 112961

"I have no extra comments or suggestions regarding the peer-review report, the second decision report of the editorial boards, and ..." [Read more]

"I have no extra comments or suggestions regarding the peer-review report, the second decision report of the editorial boards, and the review comments of the track the quality and reader’s comments of your article after publication. I feel good on the whole process of editing and publishing. Thank you for the invitation for this manuscipt, and for waiveing the publication costs for this Letter to the Editor. " [Collapse]

Jing C, Liu K. Taming colonic anastomotic leakage: Wisdom from the ancient Chinese legend of Yu the Great. World J Gastrointest Surg 2025; 17(12): 113423

"I would like to express my satisfaction with the overall review and evaluation process of our paper, which was conducted professionally ..." [Read more]

"I would like to express my satisfaction with the overall review and evaluation process of our paper, which was conducted professionally and transparently. My only minor observation is that the publication process took somewhat longer than than I expected (the article was fully accepted on September 15, 2025, but not published until December 27, 2025). However, this is more of a remark than a complaint, as I understand the operational challenges that journals sometimes face. I wish to emphasize that I have no serious concerns regarding the quality or handling of the submission process. Thank you to the journal and the reviewers for their time and effort devoted to our work. Sincerely, Enver Zerem, Corresponding Author " [Collapse]

Zerem E, Jovanovic P, Kunosic S, Kurtcehajic A, Zerem D, Zerem O. Optimal timing of pyogenic liver abscess evacuation: The role of early ultrasound-guided intervention. World J Gastrointest Surg 2025; 17(12): 110644

"I am delighted to share that my paper, Very early recurrence after pancreatic cancer resection: Unmasking the "biological R2" enigma ..." [Read more]

"I am delighted to share that my paper, Very early recurrence after pancreatic cancer resection: Unmasking the "biological R2" enigma and rethinking prognostic paradigms, has been officially published in the World Journal of Gastrointestinal Surgery. First and foremost, I would like to express my sincere gratitude to my supervisor for their invaluable guidance, rigorous academic insights, and constant encouragement throughout the research and writing process. Their mentorship was pivotal to the completion of this work. I am also deeply thankful to my co-authors for their dedicated collaboration, as well as to all the research team members who contributed to data collection, experiments, and discussions. This achievement would not have been possible without our joint efforts. My appreciation also goes to the anonymous reviewers for their constructive comments and thoughtful suggestions, which greatly enhanced the quality and rigor of the paper. I would like to extend my thanks to the editorial team of the World Journal of Gastrointestinal Surgery for their professionalism, efficiency, and patience during the peer-review and publication process. Finally, I am grateful to the funding agencies and institutions that supported this research, as well as to my family and friends for their unwavering support and understanding. I hope this paper can make a modest contribution to the advancement of pancreatic cancer treatment, and I look forward to further academic exchanges and collaborations with colleagues in the field. " [Collapse]

Wan P, Zhou SQ, Ke QH. Very early recurrence after pancreatic cancer resection: Unmasking the "biological R2" enigma and rethinking prognostic paradigms. World J Gastrointest Surg 2025; 17(12): 114403

"Author’s Comments*: The figure submission process was unnecessarily cumbersome and time-consuming. We hope the journal could streamline ..." [Read more]

"Author’s Comments*: The figure submission process was unnecessarily cumbersome and time-consuming. We hope the journal could streamline the workflow and adopt a more author-friendly policy that prioritizes scientific clarity over rigid format requirements. Specifically, if figures meet clear, objective standards for readability and resolution, authors should be able to submit them in a wider range of common formats without extensive reformatting or repeated technical checks. This would improve submission efficiency and reduce administrative burden while maintaining the quality of published visuals. " [Collapse]

Li H, Li ZP, Zhu MT, Lan CH, Wang YX, Liao P, Chen Z, Wang P, Sun JK, Shi Z, Lu PY, Lou C, Xu GH. Optimizing mesenchymal stem cell therapy for tendon-bone healing: Multifaceted approaches and future directions. World J Stem Cells 2025; 17(12): 114076

"Word Journal of Cardiovascular is a specialized academic journal focused on the field of cardiovascular medicine. It primarily ..." [Read more]

"Word Journal of Cardiovascular is a specialized academic journal focused on the field of cardiovascular medicine. It primarily publishes high-quality original research, review articles, and case reports, aiming to advance scholarly exchange and clinical practice in this discipline. The journal is typically overseen by an editorial board comprising recognized experts, and it maintains a rigorous peer-review process to ensure the academic validity and reliability of its published content. " [Collapse]

Wang LF, Zhu HJ, Wang C, Yan F, Qu CZ. Logistic regression-based risk prediction of aortic adverse remodeling following thoracic endovascular aortic repair in patients with aortic dissection. World J Cardiol 2025; 17(12): 112978

"We sincerely thank the editorial team for their efficient and constructive handling of our manuscript. The reviewers' comments were ..." [Read more]

"We sincerely thank the editorial team for their efficient and constructive handling of our manuscript. The reviewers' comments were insightful, and the editorial team's clear communication was invaluable in strengthening the final paper. We are grateful for the professionalism and support throughout the entire publication process. We are mitivated to publish more in this journal. " [Collapse]

Mulate ST, Gesese BD, Nur AM, Mengistu HB, Annose RT, Berga AE, Ulfata AL. Hepatic fascioliasis of emphasizing diagnostic difficulty and the need for high index of suspicion: Four case reports. World J Clin Cases 2025; 13(36): 113778

"Thank you very much to the editorial team for the smooth workflow throughout the publication process. The peer reviewers’ comments ..." [Read more]

"Thank you very much to the editorial team for the smooth workflow throughout the publication process. The peer reviewers’ comments were valuable and helped improve the manuscript. One possible area for improvement would be avoiding repeated requests for an English Language Certificate after clarification that all authors are native English speakers. " [Collapse]

Kim Y, See KC. Constipation in critically ill adults. World J Gastrointest Pathophysiol 2025; 16(4): 112019

"The authors of this manuscript were highly satisfied with their publication experience at the World Journal of Nephrology. Throughout ..." [Read more]

"The authors of this manuscript were highly satisfied with their publication experience at the World Journal of Nephrology. Throughout the submission, peer-review, and editorial processes, communication was professional, timely, and constructive, contributing meaningfully to the quality of the final manuscript. We sincerely appreciate the rigour and transparency of the editorial handling and the valuable feedback provided by the reviewers. We look forward to future opportunities for collaboration with the journal and would be pleased to consider the World Journal of Nephrology for our forthcoming work. " [Collapse]

Haddiya I, Simanjuntak GDFI, Ramdani S. Updates in the management of intradialytic hypotension: Emerging strategies and innovations. World J Nephrol 2025; 14(4): 109168

"On behalf of all the authors, I would like to express our sincere gratitude for the overall publication process. We are truly delighted ..." [Read more]

"On behalf of all the authors, I would like to express our sincere gratitude for the overall publication process. We are truly delighted with the constructive and insightful feedback provided during the peer-review stage, which significantly enhanced the quality and clarity of our manuscript. Furthermore, we are extremely pleased with the final product and the professional presentation of our work. The efficiency and support of the editorial team have made this a very positive experience, and we are confident that we will choose this journal again for our future research submissions. " [Collapse]

Gargallo-Bayo P, Rodrigo-Mallorca D, Calatayud J, Suso-Martí L, Vicent-Micó J, Chulvi-Medrano I. Examining the impact of blood flow restriction on cardiac rehabilitation outcomes. World J Cardiol 2025; 17(12): 111591

"I am highly impressed with your journal in multiple aspects. First and foremost, the processing speed is exceptionally efficient—from ..." [Read more]

"I am highly impressed with your journal in multiple aspects. First and foremost, the processing speed is exceptionally efficient—from submission to publication, every stage proceeds smoothly without unnecessary delays. The submission system is intuitive and user-friendly, making the entire process seamless and hassle-free. Moreover, the peer review process stands out for its promptness and high quality: the reviewers provided insightful, constructive comments that greatly enhanced the rigor of my manuscript. Following acceptance, the publication process was equally expeditious, which I truly appreciate. Overall, I am thoroughly satisfied with every dimension of your journal’s services. Thank you for your professional and diligent work throughout the entire publishing journey. " [Collapse]

Guan KY, Wu QZ, Ning B, Ling-Hu EQ. Exploration of a new method of a biopatch based on the central concept of the multi-layer repair. World J Gastrointest Surg 2025; 17(12): 113490

20280 items Read more >>

Article Quality Tracking-Peer-Review

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Huang K. Influence of obesity on the patient’s recovery after laparoscopic surgery. World J Clin Cases 2025; 13(36): 115269

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Taha R, Elsayed G, Mohamed L, Gadour E. Beyond biliary causes, fish bone perforation as a rare etiology of recurrent fever in a post-Whipple patient: A case report. World J Clin Cases 2025; 13(36): 114956

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Li QQ, Wei J, Fang LY, Zhou JL, Zhao HF. Primary ileal squamous cell carcinoma: A case report and review of literature. World J Clin Cases 2025; 13(36): 111835

"In this study, the authors describe a patient with severe ulcerative colitis resistant to treatment and comorbid health problems who ..." [Read more]

"In this study, the authors describe a patient with severe ulcerative colitis resistant to treatment and comorbid health problems who responded favorably and without side effects to the combined treatment of an α4β7 integrin antagonist (vedolizumab) and an interleukin 23p19 inhibitor (mirikizumab). This case reinforces the view, expressed over the last few years, of the need to combine two biological agents in treatment-resistant inflammatory bowel disease and in treatment-resistant patients with extraintestinal manifestations. Personally, I believe we will be led to adopt the above recommendation in the near future. What remains is the approval and adoption of this recommendation by the pharmaceutical companies manufacturing biological agents, so they can conduct extensive, multicenter studies and avoid being limited to descriptions of individual cases or series from specialized centers with very small patient numbers." [Collapse]

Guimarães AC, Ferreiro-Iglesias R, Calviño-Suarez C, Baston-Rey I, Barreiro-de Acosta M. Dual biologic therapy in patient with refractory ulcerative colitis and comorbidities: A case report. World J Gastroenterol 2025; 31(47): 113381

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? Not applicable. 2 Methods: Is the ..." [Read more]

"1 Ethics: Does the ethical approval form provided by the author meet the requirements? Not applicable. 2 Methods: Is the experimental method effective? Can it be repeated by fellow researchers (according to adequate textual/citation content presented)? Not applicable. 3 Results: Are the results true and authentic? Is the theory or hypothesis of universal significance validated or partially validated? Not applicable. 4 Figures and tables: Does the author provide perfect tables, line charts and/or graphs? Or, does the author provide figures and tables that are confusing, poorly constructed and/or not well-annotated? Yes. 5 Biostatistics: Does the author provide perfect biostatistics data? Or, does the author provide tables and line charts that have mistakes in the data? Not applicable. 6 References: Does the author scientifically and reasonably cite the latest references which are important in this field and related to the scientific problems and research hypotheses addressed in the study? Or, does the author self-cite, omit, mis-cite and/or over-cite references? Yes. 7 Language: Does the language in article correctly, clearly and concisely express the information? Or, does the article have multiple grammatical and spelling mistakes? Yes. 8 Caveats or drawbacks: What are the caveats or drawbacks for the results? They didn't provide many new ideas." [Collapse]

"These findings illuminate the pivotal role of YY1 in driving the progression of Helicobacter pylori-induced gastric carcinogenesis ..." [Read more]

"These findings illuminate the pivotal role of YY1 in driving the progression of Helicobacter pylori-induced gastric carcinogenesis through the activation of epithelial-mesenchymal transition (EMT). From a molecular vantage point, this study stands as a compelling testament to rigorous scientific inquiry, underpinned by a wealth of robust experimental evidence that substantiates its central claims. Here I only offer a suggestion and reference. In fact, cancer is a complex pathological ecosystem rather than a simple genetic disease. However, the current mainstream research perspective is greatly influenced by the "somatic mutation" theory, often believing that genes and molecules are the ultimate essence of cancer. However, such a linear reductionist view has not brought about fundamental improvements in prognosis in clinical practice, such as in targeted therapy. I believe that in the post-genomic era, we should think more about the occurrence and development of cancer from the perspectives of ecology and evolution rather than being confined to the molecular level. As I pointed out in the "Rethinking Cancer" column for the 110th anniversary of the Chinese Medical Association (https://pubmed.ncbi.nlm.nih.gov/40443342/), the key to understanding such a complex systemic disease as tumors does not lie in the relentless pursuit of genes and molecules. It can be said that the role and function (promoting or inhibiting cancer, driver, passenger or neutral) of a single gene mutation in cancer cells depend on the environment and ecological niche in which they are located. By the way, I kindly recommend the authors and your team explore the book "Rethinking Cancer" (Strauss B. et al., 2021), which is also available in Chinese version (2024, Tsinghua University Press). This book might offer a refreshing and insightful perspective on human cancers, which could help guide future research and practice and better assist in improving patient prognosis." [Collapse]

Chen JW, Ouyang JJ, Wang ZH, Ma DM, Zhang Z, Teng Q, Yu G, Li XY. Yin Yang 1 activates JAK-STAT3-mediated epithelial-mesenchymal transition in Helicobacter pylori-induced gastric cancer progression. World J Clin Oncol 2025; 16(12): 112626

"This is very interesting paper. The authors state that the Bismuth-Corlett classification, hypokalemia, and AST levels were identified ..." [Read more]

"This is very interesting paper. The authors state that the Bismuth-Corlett classification, hypokalemia, and AST levels were identified as independent risk factors for PBI following ERCP drainage. The Bismuth-Corlett classification and AST levels can be understood as risk factors for drainage infection after ERCP, but please explain why hypokalemia is a risk factor. Please state in numbers how much hypokalemia is and what the AST level is." [Collapse]

Wang YF, Han K, An N, Sun YN, Gao F, Sun Y, Zhang D, Zhao ZF, Guo Q, Gu JN, Yang Z. Risk prediction of biliary infection after endoscopic drainage for malignant perihilar biliary obstruction: A 10-year multicenter retrospective study. World J Gastroenterol 2025; 31(47): 113156

"The study is particularly strong in its development of a multimodal fusion model that integrates clinical data, radiomics, and habitat ..." [Read more]

"The study is particularly strong in its development of a multimodal fusion model that integrates clinical data, radiomics, and habitat imaging to achieve markedly superior performance in predicting early recurrence of hepatocellular carcinoma, outperforming traditional single‑modality models in both accuracy and clinical net benefit. It also excels by incorporating SHAP‑based interpretability to clarify how specific imaging and clinical features contribute to predictions, and by validating meaningful correlations between selected radiomic/habitat features and key pathological markers such as MVI, Ki‑67, and GPC‑3, thereby enhancing biological plausibility and clinical relevance." [Collapse]

Huang LH, Fang YJ, Zheng XJ, Huang C, Li CL, Yu B, Huang MJ, Qin SJ, Huang DY, Lu DW. Application of multimodal fusion technology in early recurrence prediction and pathological analysis of hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(12): 114037

"The study excels by integrating radiomics and body composition metrics from both pretreatment and follow‑up T12‑level CT scans, ..." [Read more]

"The study excels by integrating radiomics and body composition metrics from both pretreatment and follow‑up T12‑level CT scans, demonstrating that combining these imaging biomarkers with clinical data markedly improves the accuracy of survival prediction in esophageal cancer. It also stands out for using automated segmentation tools to eliminate manual variability, rigorously comparing multiple machine‑learning models, and showing that follow‑up imaging adds substantial prognostic value. Overall, the research provides a practical, non‑invasive, and clinically applicable framework that enhances personalized risk stratification when traditional L3‑level imaging is unavailable." [Collapse]

Liu MC, Cheng YY, Lin SC, Lin CH, Chuang CY, Chen WH, Liao CH, Hsieh CH, Hsieh MF, Liu YJ. Machine learning survival prediction in esophageal cancer using radiomics and body composition from pretreatment and follow-up T12-level computed tomography. World J Gastrointest Oncol 2025; 17(12): 112873

"The study demonstrates several strengths, including the safe and smooth execution of cryoablation without perioperative deaths, the ..." [Read more]

"The study demonstrates several strengths, including the safe and smooth execution of cryoablation without perioperative deaths, the clear improvement in immune function and pain reduction following treatment, and the meaningful clinical benefits such as tumor shrinkage and prolonged overall survival compared with chemotherapy alone; together, these findings highlight cryoablation as an effective, minimally invasive option that enhances quality of life and offers a promising therapeutic alternative for patients with locally advanced pancreatic cancer." [Collapse]

Kang LM, He XL, Lang L, Wang AY, Wang X, Liu YH, Zhao YH, Xu L, Yu FK, Zhang FW. Safety and efficacy of cryoablation in treating locally advanced pancreatic cancer. World J Gastrointest Oncol 2025; 17(12): 113387

"The study evaluated a WeChat‑based bowel preparation monitoring system for outpatients undergoing colonoscopy and found that, compared ..." [Read more]

"The study evaluated a WeChat‑based bowel preparation monitoring system for outpatients undergoing colonoscopy and found that, compared with traditional oral and written education, the digital system significantly reduced patients’ anxiety and depression, improved bowel cleanliness, enhanced key colonoscopy quality indicators such as cecal intubation rate and polyp detection rate, increased patient compliance with dietary and medication instructions, and lowered the incidence of adverse reactions, demonstrating that real‑time, interactive, and personalized guidance can meaningfully improve the overall effectiveness and safety of colonoscopy preparation." [Collapse]

Xi MJ, Gong YP, Tao J, Li F, Xu MY, Gu X, Bao H, Jiang S, Xu B. Exploring the improvement effect of intestinal network monitoring system on intestinal preparation quality of colonoscopy. World J Gastrointest Oncol 2025; 17(12): 111101

"The article provides a rigorous and comprehensive meta‑analysis evaluating the prognostic significance of cancer‑associated fibroblasts ..." [Read more]

"The article provides a rigorous and comprehensive meta‑analysis evaluating the prognostic significance of cancer‑associated fibroblasts in liver cancer using real‑world clinical data. It strengthens its conclusions through well‑structured subgroup analyses across different CAF markers and cancer types, offering a more nuanced understanding of their prognostic value. The study also adheres to PRISMA guidelines and includes only high‑quality research, enhancing the reliability and credibility of its findings." [Collapse]

Wei YH, Jiang WJ, Wang SQ, Cai YL, Ma XL. Cancer-associated fibroblasts, clinicopathological characteristics and prognosis of liver cancer: A systematic review and meta-analysis based on real-world research. World J Gastrointest Oncol 2025; 17(12): 110395

"It was with pleasure that I reviewed the article quality of the following manuscript: 1 Ethics: Not applicable given manuscript ..." [Read more]

"It was with pleasure that I reviewed the article quality of the following manuscript: 1 Ethics: Not applicable given manuscript type 2 Methods: Not applicable given manuscript type 3 Results: Not applicable given manuscript type 4 Figures and tables: Not applicable - non included 5 Biostatistics: Not applicable given manuscript type 6 References: References are appropriate/up to date 7 Language: Concise/well written manuscript 8 Caveats or drawbacks: None " [Collapse]

Turan B. Prognostic impact of tumor deposits in colorectal cancer. World J Gastroenterol 2025; 31(47): 114506

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

Ding YZ, Tang DQ, Zhao XJ. Esophageal fistula after resection of giant mediastinal liposarcoma: A case report. World J Clin Cases 2025; 13(35): 115410

"This is a very interesting paper. I ask some questions for you.When comparing clip-E-CIGARETTES andEUS-C+G, the varicella obliteration ..." [Read more]

"This is a very interesting paper. I ask some questions for you.When comparing clip-E-CIGARETTES andEUS-C+G, the varicella obliteration rate is 91.7% and 94.4%,respectively and rebleeding is 23.6% and 19.4%,respectively,suggesting that Clip-ECI has a slightly lower success rate.Please also consider Clip-ECI and EUS-C+G from the point of cost and procedure time.How do you deal with rebleeding cases after endoscopic procedure?Also ,please tell us about cases where endoscopic treatment is difficult." [Collapse]

Giri S, Kumar K. Gastric varices management: Is clip-assisted glue injection a real-world alternative to endoscopic ultrasound-guided therapy? World J Gastroenterol 2025; 31(46): 114149

"In recent years, knowledge of the diagnostic and therapeutic roles of stem cells in many digestive system diseases has increased ..." [Read more]

"In recent years, knowledge of the diagnostic and therapeutic roles of stem cells in many digestive system diseases has increased dramatically. Stem cells, with their inherent self-renewal and differentiation capabilities, can expand the therapeutic possibilities of modern gastroenterology across varied diagnostic and therapeutic fields. For example, as the authors of this review report, liver organoids derived from human pluripotent stem cells are used for diverse liver cancer remodeling and drug-sensitivity testing. Furthermore, mesenchymal stem cells/stromal cells are used in clinical/therapeutic studies for a large number of liver diseases. It is known that liver diseases (benign and malignant) result in high morbidity and mortality in all countries of the world. The financial burden on international health systems is becoming increasingly unsustainable in many countries, even in those that are highly developed economically. The implementation of stem cell-based diagnosis and treatment strategies for liver diseases is expected to become a reality in the near future, with visible consequences not only in the successful care of patients but also in improving healthcare economic parameters. " [Collapse]

Wang YX, Ren YN, Zhang SS, Sun S, Xu MY, Wei T, Zhang LS. Application of stem cells in the precise diagnosis and treatment of liver diseases. World J Gastroenterol 2025; 31(46): 114415

"1. This review presents a thorough and timely overview of stem cell-based strategies in the diagnosis, modeling and treatment of liver ..." [Read more]

"1. This review presents a thorough and timely overview of stem cell-based strategies in the diagnosis, modeling and treatment of liver diseases. The authors have gathered an impressive volume of literature and have covered a wide spectrum of topics that range from pluripotent stem cell differentiation to organoid systems and clinical applications. One of the most notable strengths of the manuscript is the inclusion of clinical trial information, which has been organized into clear and informative tables that greatly enhance the translational relevance of the work. Although the content is comprehensive and highly informative, the overall narrative would benefit from more concise expression because certain sections contain repeated explanations and overly detailed descriptions that affect readability. 2. References：The manuscript contains a rich and extensive reference list, which reflects careful and comprehensive literature collection. This is a clear advantage of the review and provides the reader with broad and current coverage of relevant studies. 3. Language：The manuscript generally uses appropriate scientific terminology and conveys complex concepts accurately. However, the writing occasionally becomes verbose and repetitive. Several paragraphs contain long and heavily structured sentences, repeated connective phrases and extensive lists of factors or markers. These patterns interrupt the natural flow of the text and make some sections difficult to read. A more concise presentation of key ideas and smoother transitions between paragraphs would help strengthen the clarity and coherence of the manuscript. Reducing repeated descriptions of differentiation procedures, signaling pathways and mesenchymal stem cell mechanisms would particularly improve the overall fluency. 4. Figures and tables：The figures and tables play a helpful role in supporting the manuscript. The tables summarizing differentiation methods and clinical trials are especially informative and make complex information more accessible to readers. Some figures contain a large amount of condensed information and many abbreviations, which may make them difficult to interpret at a glance. However, the authors have provided all the abbreviations right next to each table, which is very good. In addition, figure 2 that integrates the major mechanisms and introduction of stem cell-based liver organoids is exquisite visually but may require further editing conceptually. 5. Caveats or drawbacks： Although the review provides extensive information, it relies heavily on descriptive summaries and would benefit from deeper analytical discussion. Several important challenges are mentioned only briefly, such as heterogeneity among stem cell sources, safety considerations in clinical translation, variability of organoid systems and the limited outcomes of early clinical studies. A more thorough examination of these issues would give the review greater authority and balance. Overall, the manuscript offers a rich collection of information and valuable resources, especially through its comprehensive references and clinical trial summaries. The quality of the paper would be further improved by tightening the language, and reducing redundancy. I would like to comment a little bit more at the end of this ‘Track article quality’ section. The review appropriately highlights stem cell derived exosomes and extracellular vesicles, which is a valuable component of the manuscript. As far as current knowledge suggests, multiple clinical trials involving exosomes or other extracellular vesicle based therapeutics are actively underway. These vesicle based preparations may offer functional advantages comparable to their parental stem cells, while potentially avoiding several practical and safety related challenges associated with cell based therapies, including difficulties in storage, risks of uncontrolled proliferation, and concerns related to tumorigenesis. Given these advantages, a more extensive discussion of exosomes, extracellular vesicles, and their clinical development would further strengthen the manuscript. This topic may be an excellent focus for the authors to expand upon in their future work. Considering the comprehensive scope and overall quality of this review, I would also recommend it for recognition or award within the journal. " [Collapse]

Wang YX, Ren YN, Zhang SS, Sun S, Xu MY, Wei T, Zhang LS. Application of stem cells in the precise diagnosis and treatment of liver diseases. World J Gastroenterol 2025; 31(46): 114415

"The authors express concern about the lack of detailed analysis of the depth of analysis, i.e., tumor miss rates, machine learning ..." [Read more]

"The authors express concern about the lack of detailed analysis of the depth of analysis, i.e., tumor miss rates, machine learning model complexity, and dataset quality. They also discuss future directions for the potential of AI in endoscopy training to facilitate skill development and improve the overall proficiency of endoscopists, a crucial area for the future adoption of AI in clinical practice. For AI endoscopy to further develop, we need to work on updating image data and deep learning." [Collapse]

Fogas CR, Balassone V. Artificial intelligence in gastrointestinal endoscopy: Focus on analytical depth and endoscopist training. Artif Intell Gastrointest Endosc 2025; 6(4): 115140

"AI is an important milestone for future development in medicine and science. Nonetheless, there are many AI models and each model ..." [Read more]

"AI is an important milestone for future development in medicine and science. Nonetheless, there are many AI models and each model has its own learning objectives. Incorporation of multiple AI models and training machine/ learning can greatly enhance the accuracy and readiness of using it to help in hepatopathy. Also, there are many hepatopathy and a systematic way to categories them will be a challenging act." [Collapse]

Sun JR, Sun XN, Lu BJ, Deng BC. Artificial intelligence in hepatopathy diagnosis and treatment: Big data analytics, deep learning, and clinical prediction models. World J Gastroenterol 2025; 31(45): 111176

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Wu PE, Chen PJ, Su WC, Chang TK, Chen YC. Perforated sigmoid colon diverticulitis initially presenting with pneumoperitoneum, pneumoretroperitoneum, and pneumomediastinum: A case report. World J Clin Cases 2025; 13(34): 112593

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