Baishideng Publishing Group

Nachira D, Calabrese G, Senatore A, Pontecorvi V, Kuzmych K, Belletatti C, Boskoski I, Meacci E, Biondi A, Raveglia F, Bove V, Congedo MT, Vita ML, Santoro G, Petracca Ciavarella L, Lococo F, Punzo G, Trivisonno A, Petrella F, Barbaro F, Spada C, D'Ugo D, Cioffi U, Margaritora S. How to preserve the native or reconstructed esophagus after perforations or postoperative leaks: A multidisciplinary 15-year experience. World J Gastrointest Surg 2024; 16(11): 3471-3483

"World journal of gastrointestinal surgery is a high-quality journal.Editors and rewiewers give me some valuable comments.Those comments ..." [Read more]

"World journal of gastrointestinal surgery is a high-quality journal.Editors and rewiewers give me some valuable comments.Those comments are very helpful for revising and improving my article, as well as the important guiding significance to my own research.thank you for your help.and I will continue to work hard in scientific research and write more excellent articles. " [Collapse]

Liao JH, Li JS, Wang TL, Liu WS. Laparoscopic cholecystectomy plus common bile duct exploration for extrahepatic bile duct stones and postoperative recurrence-associated risk factors. World J Gastrointest Surg 2024; 16(11): 3511-3519

"The editing process has been fast and the editing quality of the article has met our expectations. The publishing format is ..." [Read more]

"The editing process has been fast and the editing quality of the article has met our expectations. The publishing format is satisfactory. The peer review report has been helpful and constructive. The rules and norms of the journal are fair and improve the quality of the article. In summary, the entire process has been satisfactory. " [Collapse]

Teja M, Garrido MI, Ocanto A, Couñago F. Prognostic impact of inflammatory and nutritional biomarkers in pancreatic cancer. World J Clin Oncol 2025; 16(1): 101191

"The peer review processes are relatively quick. There is some delay in the review processes after the revisions being fullfilled. ..." [Read more]

"The peer review processes are relatively quick. There is some delay in the review processes after the revisions being fullfilled. The publication process takes too long. Also the online Publication system can also cause some delays especially when it comes to the submission of the revised article. However overall the whole process was good and the reviewers performed a fair review raport. " [Collapse]

Christodoulidis G, Bartzi D, Koumarelas KE, Kouliou MN. Pembrolizumab in patients with gastric cancer and liver metastases: A paradigm shift in immunotherapy. World J Gastrointest Surg 2024; 16(11): 3391-3394

"1.The overall publication process of the paper is very rigorous and efficient, with clear process guidelines. 2. Your journal has ..." [Read more]

"1.The overall publication process of the paper is very rigorous and efficient, with clear process guidelines. 2. Your journal has a very clear direction for reviewing and revising manuscripts, explaining each step clearly through email. 3. Sincerely thank your journal for pointing out the shortcomings of this study, which has greatly helped us improve our research. " [Collapse]

Zhu YF, Yi FY, Qin MH, Lu J, Liang H, Yang S, Wei YZ. Factors influencing agitation during anesthesia recovery after laparoscopic hernia repair under total inhalation combined with caudal block anesthesia. World J Gastrointest Surg 2024; 16(11): 3499-3510

"Firstly, I would like to especially commend your editorial team for their efficiency and dedication in handling manuscripts. Throughout ..." [Read more]

"Firstly, I would like to especially commend your editorial team for their efficiency and dedication in handling manuscripts. Throughout the process of submitting my paper to your journal, I deeply appreciated the true meaning of "professionalism" and "dedication." From the initial submission to the acceptance of my manuscript, every step was accompanied by the editors' meticulous guidance and patient feedback. Even when faced with papers requiring revisions, the editors could swiftly and accurately point out the issues and provide constructive suggestions for improvement, which not only significantly enhanced the quality of my paper but also greatly benefited me on my academic journey. Secondly, your journal's adherence to academic integrity is admirable. During the peer review process, your journal adheres to a blind peer review system, ensuring the fairness and quality of academic evaluations. This pursuit of academic rigor not only preserves the purity of the academic community but also provides a fair and impartial platform for researchers to showcase their work. Furthermore, your journal's efforts in advancing the field of gastrointestinal surgery are remarkable. By publishing high-quality research findings, organizing thematic discussions, and publishing cutting-edge reviews, your journal not only promotes the updating and dissemination of knowledge in this field but also stimulates more innovative thinking, injecting new vitality into the development of gastrointestinal surgery and even the entire medical community. " [Collapse]

Huang XX, Gu HF, Shen PH, Chu BL, Chen Y. Meta-analysis of electrical stimulation promoting recovery of gastrointestinal function after gynecological abdominal surgery. World J Gastrointest Surg 2024; 16(11): 3559-3567

"Collaborating with the journal has always been a great experience. From the beginning, the editorial team has demonstrated remarkable ..." [Read more]

"Collaborating with the journal has always been a great experience. From the beginning, the editorial team has demonstrated remarkable attentiveness, addressing every aspect of the review process. They take the time to examine the manuscript thoroughly, ensuring that no detail is overlooked. The constructive feedback I have received has been invaluable; it has significantly contributed to refining and improving the quality. Each suggestion provided by the editors not only strengthens the arguments presented but also improves the overall impact of the manuscript, making it a more compelling read. This dedication to excellence sets this journal apart, and I appreciate the effort put into supporting authors. " [Collapse]

Krishnan A, Schneider CV, Walsh D. Proton pump inhibitors and all-cause mortality risk among cancer patients. World J Clin Oncol 2025; 16(1): 99240

"We are pleased to present the results of this multicenter study, which represents a significant collaborative effort across several ..." [Read more]

"We are pleased to present the results of this multicenter study, which represents a significant collaborative effort across several institutions. The diversity of patient populations and settings included in this study strengthens the generalizability of our conclusions and highlights the importance of broad, cooperative research in tackling complex medical questions. We want to express our gratitude to all the participating centers, researchers, and patients for their contributions to this work. This study would not have been possible without their dedication and collaboration. Thank you for publishing our study in your journal " [Collapse]

Okasha HH, Hussein HA, Ragab KM, Abdallah O, Rouibaa F, Mohamed B, Ghalim F, Farouk M, Lasheen M, Elbasiony MA, Alzamzamy AE, El Deeb A, Atalla H, El-Ansary M, Mohamed S, Elshair M, Khannoussi W, Abu-Amer MZ, Elmekkaoui A, Naguib MS, Ait Errami A, El-Meligui A, El-Habashi AH, Ameen MG, Abdelfatah D, Kaddah M, Delsa H. Role of macroscopic on-site evaluation of endoscopic ultrasound-guided fine-needle aspiration/biopsy: Results of a multicentric prospective study. World J Gastrointest Endosc 2024; 16(11): 595-606

"This is a very good submission experience. In China, traditional Chinese medicine is very common for treating malignant tumors. Our ..." [Read more]

"This is a very good submission experience. In China, traditional Chinese medicine is very common for treating malignant tumors. Our team is committed to combining traditional Chinese and Western medicine to treat malignant tumors, including colorectal cancer. We hope to have more opportunities to publish our articles in your journal in the future. " [Collapse]

Bian JY, Feng YF, He WT, Zhang T. Cohort study on the treatment of BRAF V600E mutant metastatic colorectal cancer with integrated Chinese and western medicine. World J Clin Oncol 2025; 16(1): 93670

"The journal exhibits a high level of professionalism in its peer-review process, with reviewers providing insightful and constructive ..." [Read more]

"The journal exhibits a high level of professionalism in its peer-review process, with reviewers providing insightful and constructive feedback. However, there is room for improvement in the timeliness of the review process, as the current duration can be somewhat lengthy. Despite this, the quality of the published articles remains exemplary, making it a go-to resource for researchers in the field. Overall, with some adjustments to the review timeline, this journal would be even more efficient and effective. " [Collapse]

Liu H, Wang F, Tang YL, Yan X. Asymmetric outcomes in bilateral maxillary impacted tooth extractions: A case report. World J Radiol 2024; 16(10): 608-615

"I would like to express my deepest appreciation to editor for their invaluable support and insightful feedback throughout the editing ..." [Read more]

"I would like to express my deepest appreciation to editor for their invaluable support and insightful feedback throughout the editing and review process. Their keen attention to detail and thoughtful suggestions have significantly contributed to improving the clarity, coherence, and quality of this manuscript. I am particularly grateful for their dedication and patience in guiding me through the revisions, which not only enhanced the rigor of the study but also enriched its overall impact. The editor's commitment to excellence has been instrumental in shaping this article, and I am sincerely thankful for their expertise and encouragement." " [Collapse]

Mishra M, Rao YK, Shrivastav D, Tripathi P, Singh DD. Indian perspective on childhood malnutrition: Prevalence, pathophysiology, risk factors, and prevention. World J Clin Pediatr 2024; 13(4): 91971

"Very good submission system, but I have one paper that I have submitted but have not found a reviewer yet. I hope that shortening ..." [Read more]

"Very good submission system, but I have one paper that I have submitted but have not found a reviewer yet. I hope that shortening the review process will allow us to get results faster.I hope to continue to improve the system and continue to assist the authors in their work. " [Collapse]

Feng YN, Liu LH, Zhang HW. Evaluation of the GATIS score for predicting prognosis in rectal neuroendocrine neoplasms. World J Gastroenterol 2024; 30(42): 4587-4590

"We are writing these comments with the ONLY PURPOSE to help improve the editing and publishing processes. Again, we are thankful for ..." [Read more]

"We are writing these comments with the ONLY PURPOSE to help improve the editing and publishing processes. Again, we are thankful for publishing our review. Importantly, we suggest that our comments SHOULD NOT be accessible to general public, as they are intended for the editorial and publishing offices only. It serves no purpose, and makes no sense to make our sincere, sometimes critical, comments available to “all readers.” Also, in our ~50 years of publishing peer-reviewed papers we had NEVER saw a mandatory request for comments/evaluation – this is not appropriate for an international journal published in the US. First, our positive experience: the initial review was quick; the decision also followed quickly; and, importantly, the publisher agreed to splitting the payment (which not all journals allow). It is also nice to follow the detailed “time course” of MS processing on the F6publishing site. Now, the critical comments aimed exclusively TO IMPROVE the process and ADVANCE the WJG standing, reputation, and of course impact factor: • Many times, there was no prompt response to our emails. Partly because of these delays, the processing time from “Acceptance” to online publication was so long (3.5 months). • Amazingly, many times the responders ignored our request NOT to send their response email to all the authors – instead of communicating with only co-corresponding authors. The latter is a standard policy in all the various high-ranking journals in which we published our papers. This avoids confusion, unnecessary distracting our co-authors (all extremely busy scientists) – and, indeed, is the reason for why there are corresponding authors! • IMPORTANT: you should send the proofs ONLY once, as a PDF file - EXACTLY reproducing the file to be published. There is absolutely no point in first sending a Word file, especially “Auto-Edited” which only introduces a lot of typos, incorrect formatting, etc. We wasted a lot of time correcting that “Auto-Edited” Word file, which was absolutely useless because after that we did receive - and corrected - the PDF proofs file. • Even more important: we cannot understand how it happened that the initial online publication still contained an error in Figure 2 A,B which we had corrected in the PDF proofs and which was shown correctly (as the * symbol) in the "95943.pdf" corrected proofs' file that we received FROM YOUR OFFICE in his October 15th email. It is critically important that a paper is published EXACTLY as in the PDF-proofs file corrected by the authors. Luckily, you were able to replace the initial online file, now without errors. • We cannot understand why the * symbol in Figure 2 A,B had been changed to “a” in the first instance. As we stated in our October 24 email, the * symbol is universally used to show statistical significance; it was present in Figure 2 A,B both in the original publication Ref. 21 and in our submitted MS, both in the Tiff and PowerPoint figure. Comments regarding science: • The peer review was EXTREMELY superficial; you should find reviewers with extensive knowledge/expertise in the subject. • It does not matter to us, because all the authors are world-leading experts in the field; but it reflects badly on WJG standing: what is the reason for giving “grade B” for “scientific quality,” “novelty,” “innovation,” and especially “scientific significance” (?!) to our state-of-the-art, comprehensive, paradigm-changing review ? • We don’t remember where exactly, but there even was “grade B” for the use of the English language – really ridiculous, as the editor could have simply looked (in the References) at the dozens of our publications in leading journals. Minor comments: • We understand that the References are taken directly from PubMed, and it might be, indeed, useful to have both PMID and DOI; but as we suggested in proofs, it would look much nicer if there is a unform/consistent format for all references (some titles are given in “Capitalize Every Word” format – different from most titles given in “normal” format). • Another minor, but annoying, thing: PLEASE do not include the information about Baishideng Publishing in EVERY email (and even several times within the same email). " [Collapse]

Gukovskaya AS, Lerch MM, Mayerle J, Sendler M, Ji B, Saluja AK, Gorelick FS, Gukovsky I. Trypsin in pancreatitis: The culprit, a mediator, or epiphenomenon? World J Gastroenterol 2024; 30(41): 4417-4438

"Dear Editor, Thank you for the opportunity to provide feedback on the peer-review process for my published paper. Here are my comments ..." [Read more]

"Dear Editor, Thank you for the opportunity to provide feedback on the peer-review process for my published paper. Here are my comments on the process: Transparency: The transparency of the entire peer-review process was commendable. From submission to receiving reviewer comments, there was clear communication and feedback at every step, which helped the authors understand the review progress and expected timeframes. Reviewer Selection: The professionalism and relevance of the reviewers were impressive. They had a deep understanding of the paper's topic and provided specific, constructive feedback, which was crucial for enhancing the quality of the paper. Quality of Feedback: The comments from the reviewers were professional and detailed. They not only pointed out the strengths of the paper but also offered valuable suggestions for improvement. This feedback was essential for the final refinement of the paper and maintaining academic rigor. Response Time: The duration of the peer-review cycle was reasonable and without unnecessary delays. This indicates that the journal is efficient in handling manuscripts, which is a positive factor for both authors and readers. Anonymity: Anonymity was well maintained throughout the review process, which helped reviewers provide candid comments and also protected the authors' rights. Overall, I am satisfied with the peer-review process of your journal and believe it contributes to maintaining high standards in academic publishing. I look forward to the opportunity to collaborate with your journal again in the future. " [Collapse]

Zhang HB, Duan YH, Zhou M, Liang RC. High-resolution magnetic resonance imaging in the diagnosis and management of vertebral artery dissection: A case report. World J Radiol 2024; 16(10): 593-599

"During the manuscript publication process, the editors were very conscientious and timely in handling every step of the article ..." [Read more]

"During the manuscript publication process, the editors were very conscientious and timely in handling every step of the article publication process. Peer review comments enhanced the quality of the article. All of us authors grew in the process. In the end, we are very grateful to the journal for supporting the article! " [Collapse]

Ma BS, Zhai SH, Chen WW, Zhao QN. Cardiac hypertrophy in polycythemia vera: A case report and review of literature. World J Cardiol 2024; 16(11): 651-659

"I am pleasantly surprised that your magazine offers evaluation services. I am delighted with the online submission system, the article ..." [Read more]

"I am pleasantly surprised that your magazine offers evaluation services. I am delighted with the online submission system, the article publication process, the quality of editing, and the peer review. The article was published relatively quickly; however, I could not find it on PUBMED promptly after publication. I hope this issue can be improved. " [Collapse]

Yuan JJ, Zhang HF, Zhang J, Li JZ. Mesenteric venous thrombosis in a young adult: A case report and review of the literature. World J Radiol 2024; 16(10): 569-578

"In the process of submission, we found that we need a lot of materials, and there are many requirements on the format of the paper. ..." [Read more]

"In the process of submission, we found that we need a lot of materials, and there are many requirements on the format of the paper. We hope to simplify the submission process and improve the efficiency of submission. In addition, we hope to know the time and outcome of the first review as soon as possible. Thanks again for your time and supporting. " [Collapse]

Li ZH, Ma YY, Niu LZ, Xu KC. Cryoablation for intrapulmonary bronchial cyst: A case report. World J Radiol 2024; 16(10): 616-620

"Thank-you for a rapid review process. I am especially grateful for the Baishideng policy of allowing the same manuscript to be deemed ..." [Read more]

"Thank-you for a rapid review process. I am especially grateful for the Baishideng policy of allowing the same manuscript to be deemed appropriate for another journal in the Baishideng group when the initial journal application was not successful and this not requiring a complete new submission. This has saved a large amount of time and effort. Thank-you " [Collapse]

Scriba MF, Jonas E, Chinnery GE. Predicting full-thickness necrosis in adult acute corrosive ingestion injuries in a sub-Saharan African setting. World J Gastrointest Pharmacol Ther 2024; 15(6): 99097

"Thanks the reviewers for their pertinent comments and the editors of The Magazine for their repeated proofreading and layout of the ..." [Read more]

"Thanks the reviewers for their pertinent comments and the editors of The Magazine for their repeated proofreading and layout of the journal. We are also looking forward to receiving comments from readers on the content of this article, so that we can communicate with each other and make progress together. " [Collapse]

Wang YQ, Wang Y, Jia XF, Yan QJ, Zheng XP. High complex anal fistula managed by the modified transanal opening of the intersphincteric space via the inter-sphincteric approach: A case report. World J Radiol 2024; 16(10): 552-560

"This magazine provides a platform for researchers worldwide to showcase their innovative research findings, greatly facilitating ..." [Read more]

"This magazine provides a platform for researchers worldwide to showcase their innovative research findings, greatly facilitating academic exchange and scientific progress. The editorial teams offer valuable guidance in selecting and improving manuscripts, ensuring that published articles are highly reliable and impactful. Overall, It play an indispensable role in enhancing the quality and visibility of scientific research and are an invaluable resource in the academic community. " [Collapse]

Zhang DX, Niu ZY, Wang Y, Zu M, Wu YH, Shi YY, Zhang HJ, Zhang J, Ding SG. Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases. World J Gastrointest Oncol 2024; 16(11): 4424-4435

16824 items Read more >>

Article Quality Tracking-Peer-Review

"It is said that the intestinal flora changes depending on the pathology of the liver. 1.Please explain the mechanism of the liver-gut ..." [Read more]

"It is said that the intestinal flora changes depending on the pathology of the liver. 1.Please explain the mechanism of the liver-gut axis. 2.There is a difference in the intestinal flora between cases of hepatic encephalopathy (+) and (-). In particular, in cases of encephalopathy (+), the number of streptococcus bacteria such as Streptococcus and salivarius increases, which break down urea in the intestinal tract and produce NH3. .Explain the mechanism behind the difference in gut flora between those with and without encephalopathy. " [Collapse]

Yakut A. Portocaval shunts' role in gut microbiota and hepatic encephalopathy: The gut-to-brain pathway. World J Gastroenterol 2024; 30(43): 4672-4676

"The manuscript, titled “Kill two birds with one stone: Hepatologist’s approach to metabolic dysfunction-associated steatotic liver ..." [Read more]

"The manuscript, titled “Kill two birds with one stone: Hepatologist’s approach to metabolic dysfunction-associated steatotic liver disease and heart failure,” published in the World Journal of Cardiology, addresses a vital yet underexplored intersection of heart failure (HF) and metabolic dysfunction-associated steatotic liver disease (MASLD). These conditions represent substantial public health challenges, yet their complex interaction and the potential for integrated treatment strategies have received limited attention. The authors provide a well-rounded and objective review of current knowledge on MASLD and HF, delving into their overlapping pathophysiological mechanisms and the potential benefits of coordinated therapeutic approaches. Their use of recent studies strengthens the manuscript’s scientific rigor and highlights the urgent need for further research into this intersection. The manuscript’s comprehensive coverage of epidemiology, risk factors, and treatment options for both HF and MASLD is commendable, particularly in its discussion of pharmacological interventions such as ACEIs, ARBs, SGLT-2 inhibitors, and MRAs. The authors also emphasize the critical role of Guideline-Directed Medical Therapy and lifestyle modifications in addressing these comorbidities. Additionally, their examination of emerging therapies like resmetirom for MASH with fibrosis underscores the potential impact of new treatments in this field. However, the manuscript points to several promising areas for further study. For instance, long-term data on resmetirom’s effects on HF risk are lacking, and there is limited evidence on the benefits of GLP-1 receptor agonists and tirzepatide in HF management within MASLD patients. Also notably absent is research on the effects of sacubitril/valsartan, beta-blockers, and other HF medications on MASLD outcomes. A prospective, randomized controlled trial examining the effectiveness and safety of these pharmacologic therapies in patients with both HF and MASLD would be a valuable contribution, offering essential guidance for the management of these frequently overlapping but insufficiently studied conditions. The topic holds significant clinical relevance and presents a valuable research opportunity in advancing the treatment landscape for both MASLD and HF." [Collapse]

Hirao Y, Morihara C, Sempokuya T. Kill two birds with one stone: Hapatologist’s approach to metabolic dysfunction-associated steatotic liver disease and heart failure. World J Cardiol 2024; 16(11): 660-664

"Dear Author, The Helicobacter pylori is involved in the pathogenesis of both duodenal and gastric ulcers. The duodenal ulcer patients ..." [Read more]

"Dear Author, The Helicobacter pylori is involved in the pathogenesis of both duodenal and gastric ulcers. The duodenal ulcer patients need to eat more frequent meals causing overweight (risk factor in MASLD) in the majority of cases. On the other hand, gastric ulcer patients show anorexia and post prandial pain. This condition cause weight loss in a large number of patients (protective factor in MASLD). Therefore, while evaluating the effect of H. pylori in MASLD, we should consider the existence of ulcer and its location. I recommend the respect authors to address the immunogenicity potency (existence of cag Pathogenicity Island) of the helicobacter, the severity of histology in upper gastrointestinal tract (duodenal versus gastric), and the duration of infection (assuming the patient age). " [Collapse]

Abdel-Razeq R, Bitar L, Bitar ER, Onwuzo C, Abu-Hammour MN, Eren B, Mohamed I, Johnson A, Boustany A, Onwuzo S, Asaad I. Prevalence and risk factors associated with metabolic dysfunction-associated steatohepatitis in patients with Helicobacter pylori infection: A population-based study. World J Hepatol 2024; 16(10): 1169-1176

"Dear Author, One important way of transmission is the vertical one. To eradicate the HBV, one preventive method is the identification ..." [Read more]

"Dear Author, One important way of transmission is the vertical one. To eradicate the HBV, one preventive method is the identification of seropositive pregnant woman and the application of early vaccination combined with HBIG in infants born to HBsAg-positive mothers. Besides the application of screening methods in the high-risk populations especially those with IV drug abuse and the medical staff is necessary. " [Collapse]

Marrapu S, Kumar R. Chronic hepatitis B: Prevent, diagnose, and treat before the point of no return. World J Hepatol 2024; 16(10): 1151-1157

"Dear Author, Please consider the role of gut microbiome in the pathogenesis of metabolic dysfunction-associated steatotic liver ..." [Read more]

"Dear Author, Please consider the role of gut microbiome in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD). Especially discuss the steatohepatitis caused after gut diversion methods. The prototype example is the steatohepatitis caused by the induction of small bowel bacterial overgrowth syndrome after gastric by-pass surgeries. In this setting the steatohepatitis aggravates inspite of appropriate weight loss." [Collapse]

Shan GY, Wan H, Zhang YX, Cheng JY, Qiao DR, Liu YY, Shi WN, Li HJ. Pathogenesis and research progress of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. World J Hepatol 2024; 16(10): 1142-1150

"Helicobacter pylori infection remains the most prevalent infectious disease worldwide. Although the incidence of infection has ..." [Read more]

"Helicobacter pylori infection remains the most prevalent infectious disease worldwide. Although the incidence of infection has decreased worldwide in recent years, it remains high in many countries, including the most populous country, China. Xie L et al., in their meta-analysis, found that in the years between 2014 and 2023, the prevalence of infection in China decreased compared to the previous decade (infection rate now 42.8%), with infection rates varying significantly in different geographical parts of the country. Given the relationship between HP infection and gastric cancer, any data on the incidence of HP infection in different countries is, by definition, of considerable interest since, in countries with a high incidence of gastric cancer, reducing HP infection represents the most important factor in reducing the prevalence of gastric cancer. The results of this insightful meta-analysis suggest a promising future regarding HP infection. With a further reduction in the incidence of Hp, a decrease in gastric cancer incidence in China is anticipated in the coming decades." [Collapse]

Xie L, Liu GW, Liu YN, Li PY, Hu XN, He XY, Huan RB, Zhao TL, Guo HJ. Prevalence of Helicobacter pylori infection in China from 2014-2023: A systematic review and meta-analysis. World J Gastroenterol 2024; 30(43): 4636-4656

"Summary The paper argues that the gut microbiota and the gut-brain axis (GBA) offer a promising approach to treating insomnia, ..." [Read more]

"Summary The paper argues that the gut microbiota and the gut-brain axis (GBA) offer a promising approach to treating insomnia, particularly in light of the side effects and challenges of long-term medication in Western medicine. It emphasizes the potential efficacy of TCM, including acupuncture and herbal therapies, to address these limitations. Introduction and Background Insomnia is described as a condition that impacts sleep quality and duration, leading to cognitive and social functioning deficits. The introduction of the brain-gut axis concept has illuminated the bidirectional influence between the gastrointestinal system and the central nervous system (CNS), impacting sleep through pathways involving neurotransmitters, immune responses, and the hypothalamic-pituitary-adrenal (HPA) axis. Studies suggest that insomnia may be related to dysregulation within these pathways, with inflammation and immune response playing significant roles. Intestinal Flora and Insomnia The paper explains how the composition of the gut microbiota influences brain function and sleep. Insomnia may disrupt the gut microbiome, leading to changes in specific bacterial populations, which in turn affects neurotransmitter levels and contributes to inflammatory responses. This highlights a cycle where insomnia both affects and is affected by the gut microbial ecosystem. TCM Approach to Insomnia TCM, particularly acupuncture, is posited as a therapeutic approach that influences neurotransmitters, hormones, and cytokines, potentially stabilizing circadian rhythms and sleep quality. The paper suggests that TCM could regulate the gut-brain axis to improve sleep, though it acknowledges that the precise mechanisms are not yet fully understood and calls for further research into these pathways. Conclusion The authors conclude that while TCM shows promise in treating insomnia by potentially modulating the gut-brain axis, additional studies are necessary to elucidate the specific mechanisms. This research may contribute to a deeper understanding of insomnia treatments from a microbiome perspective. Overall, this paper provides a valuable theoretical foundation for considering TCM as a viable, integrative approach to insomnia, particularly in cases where Western medication presents challenges due to side effects or dependency concerns." [Collapse]

Wang XJ. Traditional Chinese medicine treatment of insomnia based on microbial-gut-brain axis theory. World J Clin Cases 2024; 12(36): 6867-6870

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of your manuscript in World Journal of Experimental Medicine. The manuscript meets the basic requirements of scope and quality. The scientific quality of the manuscript also reaches the publication standard of World Journal of Experimental Medicine. We are grateful for your contributions." [Collapse]

Alshaikhsalama A, Archer H, Xi Y, Ljuhar R, Wells JE, Chhabra A. HIPPO artificial intelligence: Correlating automated radiographic femoroacetabular measurements with patient-reported outcomes in developmental hip dysplasia. World J Exp Med 2024; 14(4): 99359

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

Sridhar GR, Gumpeny L. Melanocortin 4 receptor mutation in obesity. World J Exp Med 2024; 14(4): 99239

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

Arora A, Morya AK, Gupta PC, Menia NK, Nishant P, Gupta V. Intravitreal therapy for the management of diabetic retinopathy: A concise review. World J Exp Med 2024; 14(4): 99235

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication ..." [Read more]

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication of your manuscript in World Journal of Experimental Medicine. The manuscript meets the basic requirements of scope and quality. The scientific quality of the manuscript also reaches the publication standard of World Journal of Experimental Medicine. We are grateful for your contributions." [Collapse]

Cheng CH, Hao WR, Cheng TH. Harnessing aryl hydrocarbon receptor dynamics: Unveiling therapeutic pathways in esophageal squamous cell carcinoma. World J Exp Med 2024; 14(4): 98599

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

Tarar ZI, Farooq U, Inayat F, Basida SD, Ibrahim F, Gandhi M, Nawaz G, Afzal A, Chaudhary AJ, Kamal F, Ali AH, Ghouri YA. Statins decrease the risk of hepatocellular carcinoma in metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis. World J Exp Med 2024; 14(4): 98543

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication ..." [Read more]

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication of your manuscript in World Journal of Experimental Medicine. The manuscript meets the basic requirements of scope and quality. The scientific quality of the manuscript also reaches the publication standard of World Journal of Experimental Medicine. We are grateful for your contributions." [Collapse]

Schuch LF, Silveira FM, Pereira-Prado V, Sicco E, Pandiar D, Villarroel-Dorrego M, Bologna-Molina R. Clinicopathological and molecular insights into odontogenic tumors associated with syndromes: A comprehensive review. World J Exp Med 2024; 14(4): 98005

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

de Paulo CB, Miglino MA, Castelucci P. Perspectives on the extracellular matrix in inflammatory bowel disease and bowel decellularization protocols. World J Exp Med 2024; 14(4): 97179

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

Cavaillon JM, Chaudry IH. Facing stress and inflammation: From the cell to the planet. World J Exp Med 2024; 14(4): 96422

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

Suleman A, Aluyi-Osa G, Ashipa F, Spadea L, Gagliano C, D’Esposito F, Zeppieri M, Musa M. Autologous blood in the management of ocular surface disorders. World J Exp Med 2024; 14(4): 96412

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication ..." [Read more]

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication of your manuscript in World Journal of Experimental Medicine. The manuscript meets the basic requirements of scope and quality. The scientific quality of the manuscript also reaches the publication standard of World Journal of Experimental Medicine. We are grateful for your contributions." [Collapse]

Maiti A, Mondal S, Choudhury S, Bandopadhyay A, Mukherjee S, Sikdar N. Oncometabolites in pancreatic cancer: Strategies and its implications. World J Exp Med 2024; 14(4): 96005

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"Thank you for submitting your manuscript to the World Journal of Experimental Medicine. Congratulations on the online publication of your manuscript in World Journal of Experimental Medicine. The manuscript meets the basic requirements of scope and quality. The scientific quality of the manuscript also reaches the publication standard of World Journal of Experimental Medicine. We are grateful for your contributions." [Collapse]

Xiang Z, Li JR, Wan WM, Li SH, Wu J. Familial hypercholesterolemia: Current limitations and future breakthroughs. World J Exp Med 2024; 14(4): 99968

"Thank you for submitting your manuscript to the World Journal of Experimental Medicine.Congratulations on the online publication of ..." [Read more]

Wibowo DP, Agustiningsih A, Jayanti S, Sukowati CHC, El Khobar KE. Exploring the impact of hepatitis B immunoglobulin and antiviral interventions to reduce vertical transmission of hepatitis B virus. World J Exp Med 2024; 14(4): 95960

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Seif El-Din Z, Afify M, Zayed E, Elsabaawy D, Tharwa ES, Elsharawy A, Abdelsameea E, Rady MA. Dapagliflozin as an oral antihyperglycemic agent in the management of diabetes mellitus in patients with liver cirrhosis. World J Exp Med 2024; 14(4): 95272

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 3064

Peer-reviewers: 25733

Manuscripts received today: 12

Manuscript reviews today: 45

Unhandled manuscripts today: 142

Active peer-reviewers today: 7301

Reviewer acceptance today: 48

Reviewer refusals today: 101

Total accepted manuscripts: 33707

Total rejected manuscripts: 39072

Total peer-reviewers: 3566519

Total submissions: 31898